The DOI matches its Crossref record; 56 of the 56 references it cites were found in a registry or an index.
T cell metabolism drives immunity
Open accessAbstract
Lymphocytes must adapt to a wide array of environmental stressors as part of their normal development, during which they undergo a dramatic metabolic remodeling process. Research in this area has yielded surprising findings on the roles of diverse metabolic pathways and metabolites, which have been found to regulate lymphocyte signaling and influence differentiation, function and fate. In this review, we integrate the latest findings in the field to provide an up-to-date resource on lymphocyte metabolism.
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Citations
Cites
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“This leads to overreduction of the electron carrier coenzyme Q, causing reverse electron transport through mitochondrial complex I and, subsequently, excessive ROS production (Chouchani et al., 2014; O’Neill, 2014).”
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Cited by
Bile acid metabolites control TH17 and Treg cell differentiation
Hang, S., Paik, D., Yao, L., Kim, E., Trinath, J., Lu, J., Ha, S., Nelson, B. N., Kelly, S. P., Wu, L., et al. (2019) · Nature · doi:10.1038/s41586-019-1785-z · Cited by 1,457
Mitochondrial Dynamics Controls T Cell Fate through Metabolic Programming
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Self-citationAnti-inflammatory effect of IL-10 mediated by metabolic reprogramming of macrophages
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Biology and therapeutic potential of interleukin-10
Saraiva, M., Vieira, P., & O’Garra, A. (2020) · Journal of Experimental Medicine · doi:10.1084/jem.20190418 · Cited by 1,118
Bengsch, B., Johnson, A. L., Kurachi, M., Odorizzi, P. M., Pauken, K. E., Attanasio, J., Stelekati, E., McLane, L. M., Paley, M. A., Delgoffe, G. M., et al. (2016) · Immunity · doi:10.1016/j.immuni.2016.07.008 · Cited by 868
“Teff cells generated during acute infections switch to anabolic metabolism dominated by aerobic glycolysis (Buck et al., 2015).”
BackgroundInfluential
Metadata
- Authors
- Buck, M. D., O’Sullivan, D., & Pearce, E. L.
- Venue
- Journal of Experimental Medicine
- Publisher
- Rockefeller University Press
- Published
- 2015-08-10
- Volume
- 212
- Issue
- 9
- Pages
- 1345-1360
- ISSN
- 0022-1007 (ISSN-L)
- 1540-9538
- OpenAlex
- W2116676186
- Cited by
- 1,179
- References
- 56
- FWCI
- 41.91
- Type
- journal article
- Language
- en
- Open access
- bronze
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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