Inflammatory signaling regulates hematopoietic stem and progenitor cell development and homeostasis

The Placenta Harbors a Unique Microbiome

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Hematopoietic Stem Cells Reversibly Switch from Dormancy to Self-Renewal during Homeostasis and Repair

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IFNα activates dormant haematopoietic stem cells in vivo

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Haematopoietic stem cells derive directly from aortic endothelium during development

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Blood stem cells emerge from aortic endothelium by a novel type of cell transition

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Mice lacking granulocyte colony-stimulating factor have chronic neutropenia, granulocyte and macrophage progenitor cell deficiency, and impaired neutrophil mobilization

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Hematopoietic stem cells through the ages: A lifetime of adaptation to organismal demands

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The impact of interleukin-6 (IL-6) and mesenchymal stem cell-derived IL-6 on neurological conditions

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Myeloid progenitor dysregulation fuels immunosuppressive macrophages in tumours

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Maternal inflammation regulates fetal emergency myelopoiesis

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Blood and guts: how the intestinal microbiome shapes hematopoiesis and treatment of hematologic disease

Sanchez, J. F., Maknojia, A., & King, K. Y. (2024) · Blood · doi:10.1182/blood.2023021174 · Cited by 41

STING activation in TET2-mutated hematopoietic stem/progenitor cells contributes to the increased self-renewal and neoplastic transformation

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IRF1 regulates self-renewal and stress responsiveness to support hematopoietic stem cell maintenance

Nilsson, A. R., Xian, H., Shalapour, S., Cammenga, J., & Karin, M. (2023) · Science Advances · doi:10.1126/sciadv.adg5391 · Cited by 33

Modeling the Effects of Protracted Cosmic Radiation in a Human Organ‐on‐Chip Platform

Tavakol, D. N., Nash, T. R., Kim, Y., Graney, P. L., Liberman, M., Fleischer, S., Lock, R. I., O'Donnell, A., Andrews, L., Ning, D., et al. (2024) · Advanced Science · doi:10.1002/advs.202401415 · Cited by 30

Emergency myelopoiesis in solid cancers

Aliazis, K., Yenyuwadee, S., Phikulsod, P., & Boussiotis, V. A. (2024) · British Journal of Haematology · doi:10.1111/bjh.19656 · Cited by 34

The microbiota regulates hematopoietic stem and progenitor cell development by mediating inflammatory signals in the niche

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The fetal programming effect of maternal immune activation (MIA) on the offspring’s immune system

Hofsink, N., Groenink, L., & Plösch, T. (2024) · Seminars in Immunopathology · doi:10.1007/s00281-024-01023-8 · Cited by 25

Ecological insights into hematopoiesis regulation: unraveling the influence of gut microbiota

Zheng, K., Wei, Z., & Li, W. (2024) · Gut Microbes · doi:10.1080/19490976.2024.2350784 · Cited by 22

Hematopoietic Progenitors and the Bone Marrow Niche Shape the Inflammatory Response and Contribute to Chronic Disease

Xu, Y., Murphy, A. J., & Fleetwood, A. J. (2022) · International Journal of Molecular Sciences · doi:10.3390/ijms23042234 · Cited by 23

Vasopressin drives aberrant myeloid differentiation of hematopoietic stem cells, contributing to depression in mice

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Maternal NO 2 exposure and fetal growth restriction: Hypoxia transmission and lncRNAs-proinflammation-mediated abnormal hematopoiesis

Qin, L., Yue, H., Gong, Z., Guo, Y., Li, D., Ma, L., YiXi, Z., He, J., Li, Z., Li, G., et al. (2024) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.2409597121 · Cited by 18

Microbial Sensing by Hematopoietic Stem and Progenitor Cells

Barman, P. K., & Goodridge, H. S. (2022) · Stem Cells · doi:10.1093/stmcls/sxab007 · Cited by 19

Regulation of lymphoid-myeloid lineage bias through regnase-1/3-mediated control of Nfkbiz

Uehata, T., Yamada, S., Ori, D., Vandenbon, A., Giladi, A., Jelinski, A., Murakawa, Y., Watanabe, H., Takeuchi, K., Toratani, K., et al. (2023) · Blood · doi:10.1182/blood.2023020903 · Cited by 17

Acute and Chronic Tnf-α-Induced Effects on Hematopoietic Stem Cells are Fully Reversible

Nilsson, A. R., Hidalgo, I., Bryder, D., & Pronk, C. J. (2022) · iScience · doi:10.1016/j.isci.2023.106341 · Cited by 17

Single-cell omics identifies inflammatory signaling as a trans-differentiation trigger in mouse embryos

Zhang, Y., Kang, Z., Liu, M., Wang, L., & Liu, F. (2024) · Developmental Cell · doi:10.1016/j.devcel.2024.02.010 · Cited by 15

TLR2 regulates hair follicle cycle and regeneration via BMP signaling

Xiong, L., Zhevlakova, I., West, X. Z., Gao, D., Murtazina, R., Horak, A. J., Brown, J. M., Molokotina, I., Podrez, E. A., & Byzova, T. V. (2024) · eLife · doi:10.7554/elife.89335.3 · Cited by 15

PU.1 is required to restrain myelopoiesis during chronic inflammatory stress

Chavez, J. S., Rabe, J. L., Niño, K. E., Wells, H. H., Gessner, R. L., Mills, T. S., Hernandez, G., & Pietras, E. M. (2023) · Frontiers in Cell and Developmental Biology · doi:10.3389/fcell.2023.1204160 · Cited by 14

A microbiome-macrophage-iron axis guides stressed hematopoietic stem cell fate

Caiado, F., & Manz, M. G. (2022) · Cell stem cell · doi:10.1016/j.stem.2022.01.009 · Cited by 13

Hematopoietic stem cell a reservoir of innate immune memory

Ruffinatto, L., Groult, Y., Iacono, J., Sarrazin, S., & de Laval, B. (2024) · Frontiers in Immunology · doi:10.3389/fimmu.2024.1491729 · Cited by 14

Maintenance of hematopoietic stem cells by tyrosine-unphosphorylated STAT5 and JAK inhibition

Williams, M., Wang, X., Bastos, H. P., Grondys-Kotarba, G., Johnson, C., Mende, N., Calderbank, E. F., Wantoch, M., Park, H. J., Wu, Q., et al. (2024) · Blood Advances · doi:10.1182/bloodadvances.2024014046 · Cited by 17

Baseline neutrophil-lymphocyte ratio (NLR) predicts toxicity and survival in HR+/HER-2 breast cancer patients treated with CDK4/6 inhibitors

Badran, O., Darawshe, A., Sharif, S., Yosef, S., & Bar‐Sela, G. (2025) · The Breast · doi:10.1016/j.breast.2025.104568 · Cited by 11

Deregulated protein homeostasis constrains fetal hematopoietic stem cell pool expansion in Fanconi anemia

Kovuru, N., Mochizuki‐Kashio, M., Menna, T. N., Jeffrey, G., Hong, Y., Yoon, Y. M., Zhang, Z., & Kurre, P. (2024) · Nature Communications · doi:10.1038/s41467-024-46159-1 · Cited by 11

IκBα controls dormancy in hematopoietic stem cells via retinoic acid during embryonic development

Thambyrajah, R., Maqueda, M., Fadlullah, M. Z. H., Proffitt, M., Neo, W. H., Guillén, Y., Casado-Peláez, M., Molinero, P. H., Brujas, C., Castelluccio, N., et al. (2024) · Nature Communications · doi:10.1038/s41467-024-48854-5 · Cited by 15

IFN-I-mediated neutropoiesis bias drives neutrophil priming and inflammatory comorbidities

Li, Y., Chen, Y., Deng, C., Niu, Y., Yang, Y., Sun, S., Hu, Z., Wei, Y., Xu, M., Huang, Y., et al. (2025) · Theranostics · doi:10.7150/thno.110859 · Cited by 10

Basal type I interferon signaling has only modest effects on neonatal and juvenile hematopoiesis

Li, Y., Yang, W., Wang, H. C., Patel, R. M., Casey, E. B., Denby, E., & Magee, J. A. (2023) · Blood Advances · doi:10.1182/bloodadvances.2022008595 · Cited by 9

Adverse hematological profiles associated with chlorpromazine antipsychotic treatment in male rats: Preventive and reversal mechanisms of taurine and coenzyme-Q10

Obukohwo, O. M., Ben‐Azu, B., Nwangwa, E. K., Ejiro, O. P., Igweh, J. C., & Adeogun, A. E. (2024) · Toxicology Reports · doi:10.1016/j.toxrep.2024.04.004 · Cited by 10

The indispensability of methyltransferase-like 3 in the immune system: from maintaining homeostasis to driving function

Zhang, M., Gou, Z., Qu, Y., & Su, X. (2024) · Frontiers in Immunology · doi:10.3389/fimmu.2024.1456891 · Cited by 9

Emergency Hematopoiesis in the Pathobiology of COVID-19: The Dark Side of an Early Innate Protective Mechanism

Balandrán, J. C., Zamora-Herrera, G., Romo‐Rodríguez, R., & Pelayo, R. (2022) · Journal of Interferon & Cytokine Research · doi:10.1089/jir.2022.0028 · Cited by 11

Deciphering bone marrow engraftment after allogeneic stem cell transplantation in humans using single-cell analyses

Bordenave, J., Gajda, D., Michonneau, D., Vallet, N., Chevalier, M. F., Clappier, E., Lemaire, P., Mathis, S., Robin, M., Xhaard, A., et al. (2024) · Journal of Clinical Investigation · doi:10.1172/jci180331 · Cited by 9

The impact of prenatal inflammation on hematopoietic development

Tseng, N. A., & Beaudin, A. E. (2023) · Current Opinion in Hematology · doi:10.1097/moh.0000000000000770 · Cited by 8

CAR T cell–mediated bone marrow inflammation causes hematotoxicity and favors clonal hematopoiesis

Khelil, M. B., Arbab, A., Srikanthan, J., Marcos-Kovandzic, L., Vergé, V., Pagès, A., Rengassamy, J., Amine-Hneineh, R., Aglave, M., Jelin, R., et al. (2025) · Science Translational Medicine · doi:10.1126/scitranslmed.adu9790 · Cited by 10

TLR2 regulates hair follicle cycle and regeneration via BMP signaling

Xiong, L., Zhevlakova, I., West, X. Z., Gao, D., Murtazina, R., Horak, A. J., Brown, J. M., Molokotina, I., Podrez, E. A., & Byzova, T. V. (2023) · eLife · doi:10.7554/elife.89335 · Cited by 21

Systematic single-cell analysis reveals dynamic control of transposable element activity orchestrating the endothelial-to-hematopoietic transition

Feng, C., Tie, R., Xin, S., Chen, Y., Li, S., Chen, Y., Hu, X., Zhou, Y., Liu, Y., Hu, Y., et al. (2024) · BMC Biology · doi:10.1186/s12915-024-01939-5 · Cited by 8

Clearing the Haze: How Does Nicotine Affect Hematopoiesis before and after Birth?

Cool, T., y Baena, A. R., & Forsberg, E. C. (2021) · Cancers · doi:10.3390/cancers14010184 · Cited by 6

Inhibition of osteosarcoma lung metastases by β-glucan and CD40 agonist is mediated by activation of macrophages and NK cells

Shrestha, P., Shrestha, R., & Kleinerman, E. S. (2025) · Journal for ImmunoTherapy of Cancer · doi:10.1136/jitc-2025-012510 · Cited by 6

Erythropoiesis in health and disease: Distinguishing defective and ineffective erythropoiesis

Hoss, S. E., Lizarralde-Iragorri, M. A., Maciel, T. T., & Hermine, O. (2026) · HemaSphere · doi:10.1002/hem3.70297 · Cited by 8

E3 ubiquitin ligase on the biological properties of hematopoietic stem cell

Zhan, Q., Wang, J., Zhang, H., & Zhang, L. (2023) · Journal of Molecular Medicine · doi:10.1007/s00109-023-02315-6 · Cited by 5

Distinct roles of hematopoietic cytokines in the regulation of leukemia stem cells in murine MLL-AF9 leukemia

Li, Y., Seet, C. S., Mack, R. M., Joshi, K., Runde, A. P., Hagen, P. A., Barton, K., Breslin, P., Kini, A. R., Ji, H., et al. (2023) · Stem Cell Reports · doi:10.1016/j.stemcr.2023.11.003 · Cited by 5

Effects of Staphylococcus aureus on stem cells and potential targeted treatment of inflammatory disorders

Liu, Z., Liu, G., Lin, Z., Chen, Y., Chen, P., Hu, Y., Yu, B., & Jiang, N. (2024) · Stem Cell Research & Therapy · doi:10.1186/s13287-024-03781-6 · Cited by 5

Loss of BAP1 defines a unique subtype of TP53-mutated de novo AML and confers sensitivity to BCL-xL inhibitors

Andricovich, J., Lap, C. J. G., & Tzatsos, A. (2025) · Blood · doi:10.1182/blood.2024026417 · Cited by 6

Chronic Comorbidities in Middle Aged Patients Contribute to Ineffective Emergency Hematopoiesis in Covid-19 Fatal Outcomes

Romo‐Rodríguez, R., Anda, K. V. G.-D., López-Blanco, J. A., Zamora-Herrera, G., Cortés-Hernández, P., Santos‐López, G., Márquez‐Domínguez, L., Vilchis-Ordóñez, A., Ramírez-Ramírez, D., Balandrán, J. C., et al. (2023) · Archives of Medical Research · doi:10.1016/j.arcmed.2023.03.003 · Cited by 6

An interactive resource of molecular signalling in the developing human haematopoietic stem cell niche

Crosse, E. I., Binagui-Casas, A., Gordon-Keylock, S. A. M., Александрович, Р. С., Tamagno, S., Olofsson, D., Anderson, R. A., & Medvinsky, A. (2023) · Development · doi:10.1242/dev.201972 · Cited by 5

Identification of diagnostic molecules and potential therapeutic agents for atopic dermatitis by single-cell RNA sequencing combined with a systematic computing framework that integrates network pharmacology

Zhang, X., Ding, C., & Zhao, Z. (2023) · Functional & Integrative Genomics · doi:10.1007/s10142-023-01005-3 · Cited by 5

Mycobacterium tuberculosis infection drives differential responses in the bone marrow hematopoietic stem and progenitor cells

Bobba, S., Howard, N. C., Das, S., Ahmed, M., Khan, N., Marchante, I. S., Barreiro, L. B., Sanz, J., Divangahi, M., & Khader, S. A. (2023) · Infection and Immunity · doi:10.1128/iai.00201-23 · Cited by 5

Impact of macrophage differentiation on hematopoietic function enhancement by Shenzhu ErKang Syrup

Li, Y., Teng, M., Yang, H., Li, S., Liu, X., Zhang, J., Qiu, Y., & Li, L.-Z. (2024) · Aging · doi:10.18632/aging.205358 · Cited by 5

Zebrafish models of inflammation in hematopoietic development and disease

Ketharnathan, S., Rajan, V., Prykhozhij, S. V., & Berman, J. N. (2022) · Frontiers in Cell and Developmental Biology · doi:10.3389/fcell.2022.955658 · Cited by 4

Red Ginseng Extract and γ-Aminobutyric Acid Synergistically Enhance Immunity Against Cancer Cells and Antitumor Metastasis Activity in Mice

Lim, J. S., Kim, C. R., Shin, K. S., Park, H. J., & Yoon, T. J. (2022) · Journal of Medicinal Food · doi:10.1089/jmf.2022.k.0079 · Cited by 4

IκBα controls dormancy induction in Hematopoietic stem cell development via retinoic acidPreprint

Thambyrajah, R., Fadlullah, M. Z. H., Proffitt, M., Neo, W. H., Guillén, Y., Casado-Peláez, M., Molinero, P. H., Brujas, C., Castelluccio, N., González, J., et al. (2022) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2022.11.17.516971 · Cited by 4

IFN alpha signaling drives hematopoietic stem cells malfunction under acute inflammation

Han, X., Zhao, M., Wang, K., Ma, W., Wu, B., Yu, Y., Liang, X., Mo, W., Chen, X., Zhou, M. D., et al. (2025) · International Immunopharmacology · doi:10.1016/j.intimp.2025.114012 · Cited by 3

Tissue-scale mapping reveals a central role of hepatoblasts in the regulation of fetal liver hematopoiesis and stem cell maintenance

Vijaykumar, A., Helbling, P. M., Thelen, F., Fazio, S., Mun, Y., Pereira, A. L., Zielińska, K. A., Büschl, P., Zerjatke, T., Loosli, K., et al. (2026) · Developmental Cell · doi:10.1016/j.devcel.2026.01.011 · Cited by 3

KDM6A Deficiency Induces Myeloid Bias and Promotes CMML‐Like Disease Through JAK/STAT3 Activation by Repressing SOCS3

Chen, H., Wang, S., Dong, R., Yu, P., Li, T., Hu, L., Wang, M., Qian, Z., Zhou, H., Yue, X., et al. (2025) · Advanced Science · doi:10.1002/advs.202413091 · Cited by 3

Flared inflammatory episode transforms advanced myelodysplastic syndrome into aplastic pancytopenia: A case report and literature review

Ju, B., Xiu, N.-N., Xu, J. M. S., Yang, X., Sun, X.-Y., & Zhao, X.-C. (2023) · World Journal of Clinical Cases · doi:10.12998/wjcc.v11.i17.4105 · Cited by 3

CD82 expression marks the endothelium to hematopoietic transition at the onset of blood specification in human

Menegatti, S., Potts, B., Paredes, R., García-Alegría, E., Baker, S. M., & Kouskoff, V. (2023) · iScience · doi:10.1016/j.isci.2023.107583 · Cited by 3

Tissue-scale dynamic mapping of Hematopoietic Stem Cells and supportive niche cells in the fetal liverPreprint

Helbling, P. M., Vijaykumar, A., Gomariz, Á., Zerkatje, T., Zielińska, K. A., Loosli, K., Isringhausen, S., Nagasawa, T., Roeder, I., Manz, M. G., et al. (2023) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2023.09.12.554625 · Cited by 3

IL-27 limits HSPC differentiation during infection and protects from stem cell exhaustion

Aldridge, D. L., Lanzar, Z. R., Phan, A. T., Christian, D. A., Pardy, R. D., Min, B., Kedl, R. M., & Hunter, C. A. (2025) · eLife · doi:10.7554/elife.105876.3 · Cited by 2

Bone marrow transplantation attenuates inflammation and improves glycemic control in type 2 non-obese diabetic Goto-Kakizaki rats

Borges, J. C. D. O., Correa, I. S., Gimenes, G. M., Ferreira, L. D. A., Silva, M. A. R. D. M., Pauferro, J. R. B., Lobato, T. B., Alves, A. C. D. A., Pereira, A. C. G., Souza, K. O., et al. (2025) · Molecular and Cellular Endocrinology · doi:10.1016/j.mce.2025.112716 · Cited by 2

Metabolic and epigenetic interplay in HSPC specification: A balance between extrinsic and intrinsic cues

Kalogeraki, M., Rondeau, V., Nader, Z. A., Espéli, M., & Balabanian, K. (2026) · iScience · doi:10.1016/j.isci.2026.114921 · Cited by 2

The impact of metronidazole on pain persistence after fertility-sparing endometriosis surgery: METROFERT randomized study

Quevedo, A., Parikh, S., Reinstine, J., Chamseddine, P., Gaskins, J., Whalen, C., Biscette, S. M., & Pasic, R. P. (2024) · American Journal of Obstetrics and Gynecology · doi:10.1016/j.ajog.2024.07.006 · Cited by 2

Aryl hydrocarbon receptor restrains tonic cytokine responses by inhibiting microbiota sensing in monocytes

Cros, A., Rigamonti, A., de Juan, A., Coillard, A., Rieux-Laucat, M., Tabtim-On, D., Papillon, E., Goudot, C., Cepika, A., Banchereau, R., et al. (2025) · Journal of Clinical Investigation · doi:10.1172/jci189937 · Cited by 2

TLR2 Regulates Hair Follicle Cycle and Regeneration via BMP SignalingPreprint

Xiong, L., Zhevlakova, I., West, X. Z., Gao, D., Murtazina, R., Horak, A. J., Brown, J. M., Molokotina, I., Podrez, E. A., & Byzova, T. V. (2023) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2023.08.14.553236 · Cited by 2

Bnip3lb-driven mitophagy sustains expansion of the embryonic hematopoietic stem cell poolPreprint

Meader, E., Walcheck, M. T., Leder, M. R., Jing, R., Wrighton, P. J., Sugden, W. W., Najia, M. A. T., Oderberg, I. M., Taylor, V. M., LeBlanc, Z. C., et al. (2024) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2024.09.23.614531 · Cited by 2

IL-27 limits HSPC differentiation during infection and protects from stem cell exhaustionPreprint

Aldridge, D. L., Lanzar, Z. R., Phan, A. T., Christian, D. A., Pardy, R. D., Min, B., Kedl, R. M., & Hunter, C. A. (2025) · eLife · doi:10.7554/elife.105876 · Cited by 2

Towards an integrated understanding of inflammatory pathway influence on hematopoietic stem and progenitor cell differentiation

Allara, M., & Girard, J. R. (2024) · BioEssays · doi:10.1002/bies.202300142 · Cited by 1

Leukemogenic Kras mutation reprograms multipotent progenitors to facilitate its spread through the hematopoietic system

Jang, G., Park, R., Esteva, E., Hsu, P.-F., Feng, J., Upadhaya, S., Sawai, C. M., Aifantis, I., Fooksman, D., & Reizis, B. (2025) · The Journal of Experimental Medicine · doi:10.1084/jem.20240587 · Cited by 2

Causal Effects of Inflammatory Cytokines on Urethral Stricture Disease: A Bidirectional Mendelian Randomization Study

Chong, Y., Li, X., Peng, Z., Wang, Z., Fu, D., Huang, Z. L., & Chong, T. (2025) · Annals of Human Genetics · doi:10.1111/ahg.70002 · Cited by 1

Plasmin and sterile inflammation jointly drive fatal embryonic liver degeneration in endothelial chromatin remodeler mutant mice

Wu, M., Rudenko, Y., & Griffin, C. T. (2026) · Development · doi:10.1242/dev.205538 · Cited by 1

Aging mechanisms and rejuvenation strategies for hematopoietic stem cells

Zhang, Y., Xu, Y., Shi, W., Cao, D., Guo, D.-A., & Yue, R. (2026) · Genome biology · doi:10.1186/s13059-026-04119-6 · Cited by 1

Human HSPC clones balance stochastic diversification with cytokine-induced differentiation

Colin, E., Brook, D., Izraeli, J., Milman, O., Lifshitz, A., Bacharach, T., Chapal-Ilani, N., Shlush, L. I., & Tanay, A. (2026) · Blood · doi:10.1182/blood.2026033834 · Cited by 2

Integrated Multi-Omics and Interactome Analysis of CDK8 Inhibition Reveals Erythroid Differentiation Programs and Therapeutic Synergy with BET Blockade in AML

Statkiewicz, M., Rumieńczyk, I., Pakulska, U., Obacz, M., Kulecka, M., Cendrowski, J., Cubulska-Lubak, M., Kaniuga, E., Sandowska-Markiewicz, Z., Ślusarczyk‐Kacprzyk, W., et al. (2026) · Cells · doi:10.3390/cells15151414 · Cited by 1

Emergency granulopoiesis and innate immune memory in inflammatory bowel disease

Pires, S., & Longman, R. (2026) · Trends in Immunology · doi:10.1016/j.it.2026.07.004 · Cited by 1

Can Lacticaseibacillus rhamnosus CRL1505 postbiotic improve emergency myelopoiesis in immunocompromised mice?

Lopez, A. G., Vasile, B., Kolling, Y., Ivir, M., Gutiérrez, F., Alvarez, S., & Salva, S. (2024) · Microbes and Infection · doi:10.1016/j.micinf.2024.105311 · Cited by 2

HES1 is required for mouse fetal hematopoiesis

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Trained and ready - the case for an inflammatory memory for hematopoietic stem and progenitor cells in the AML niche

Chen, D.-W., Wafula, E. K., & Kurre, P. (2024) · Oncotarget · doi:10.18632/oncotarget.28642 · Cited by 1

Connexin 41.8 governs timely haematopoietic stem and progenitor cell specification

Petzold, T., Brivio, S., Linnerz, T., Watanabe, M., Gerhardt, H., & Bertrand, J. Y. (2025) · Biology Open · doi:10.1242/bio.062118 · Cited by 1

Acute and Chronic Tnf-α-Induced Effects on Hematopoietic Stem Cells are Fully ReversiblePreprint

Nilsson, A. J. S. R., Hidalgo, I., Bryder, D., & Pronk, C. J. (2022) · SSRN Electronic Journal · doi:10.2139/ssrn.4169244 · Cited by 1

TLR2 Regulates Hair Follicle Cycle and Regeneration via BMP SignalingPreprint

Xiong, L., Zhevlakova, I., West, X. Z., Gao, D., Murtazina, R., Horak, A. J., Brown, J. M., Molokotina, I., Podrez, E. A., & Byzova, T. V. (2024) · eLife · doi:10.7554/elife.89335.2 · Cited by 1

Maintenance of haematopoietic stem cells by JAK inhibition and increased tyrosine-unphosphorylated STAT5Preprint

Williams, M., Wang, X., Bastos, H. P., Grondys-Kotarba, G., Johnson, C. S., Mende, N., Calderbank, E. F., Wantoch, M., Park, H. J., Wu, Q., et al. (2024) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2024.05.29.596460 · Cited by 1

Semaphorin 4A maintains functional diversity of the hematopoietic stem cell poolPreprint

Toghani, D., Gupte, S., Zeng, S., Mahammadov, E., Crosse, E. I., Seyedhassantehrani, N., Burns, C. S., Gravano, D. M., Radtke, S., Kiem, H., et al. (2024) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2024.11.12.622506 · Cited by 1

Caspase-1 self-terminates protease activity to enforce homeostasis and prevent inflammasome-driven diseasesPreprint

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IL-27 limits HSPC differentiation during infection and protects from stem cell exhaustionPreprint

Aldridge, D. L., Lanzar, Z. R., Phan, A. T., Christian, D. A., Pardy, R. D., Min, B., Kedl, R. M., & Hunter, C. A. (2025) · eLife · doi:10.7554/elife.105876.2 · Cited by 1

Maternal IL-10 restricts fetal emergency myelopoiesisPreprint

Collins, A., Swann, J. W., Proven, M. A., Patel, C. M., Mitchell, C. A., Kasbekar, M., Dellorusso, P. V., & Passegue, E. A. (2023) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2023.09.13.557548

TLR2 Regulates Hair Follicle Cycle and Regeneration via BMP SignalingPreprint

Xiong, L., Zhevlakova, I., West, X. Z., Gao, D., Murtazina, R., Horak, A. J., Brown, J. M., Molokotina, I., Podrez, E. A., & Byzova, T. V. (2023) · eLife · doi:10.7554/elife.89335.1

The Immune System and Hematopoietic Stem Cells

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‘Nomadic’ Hematopoietic Stem Cells Navigate the Embryonic Landscape

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Advances in Modern Medical Research on the Hematopoietic Effect of Qi and Blood Replenishing Drugs

段, 爽. (2025) · Medical Diagnosis · doi:10.12677/md.2025.151017

IL-27 limits HSPC differentiation during infection and protects from stem cell exhaustionPreprint

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rapunzel5 is necessary for normal hematopoietic development in zebrafishPreprint

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Plasmin activity and sterile inflammation synergize to promote lethal embryonic liver degenerationPreprint

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Setd2 ensures the establishment of a precise basal inflammatory state within murine hematopoietic stem/progenitor cells

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Additional file 1 of HES1 is required for mouse fetal hematopoiesis

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Gpr171 regulates embryonic hematopoietic stem cell emergence via ERK1/2 and Notch signaling

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Bnip3lb-driven mitophagy maintains fate of the embryonic hematopoietic stem cell pool

Meader, E., Walcheck, M. T., Leder, M. R., Delaney, P., Falchetti, M., Jing, R., Li, C., Kambli, N. K., Wrighton, P. J., Sugden, W. W., et al. (2026) · Nature Communications · doi:10.1038/s41467-026-69593-9

IFN-γ induces hematopoietic stem cell myelopoiesis through Meis1 in tumor

Han, X., Zhao, M., Wang, K., Ma, W., Zhu, S., Zhou, R., Yu, U., Jiang, B., Bai, X., Lei, P., et al. (2026) · Stem Cell Research & Therapy · doi:10.1186/s13287-026-04968-9 · Cited by 1

Integrated Multi-Omics and Interactome Analysis of CDK8 Inhibition Reveals Erythroid Differentiation Programs and BET Synergy in AML Stem-like CellsPreprint

Statkiewicz, M., Rumieńczyk, I., Pakulska, U., Obacz, M., Kulecka, M., Cendrowski, J., Cubulska-Lubak, M., Kaniuga, E., Sandowska-Markiewicz, Z., Ślusarczyk‐Kacprzyk, W., et al. (2026) · Research Square · doi:10.21203/rs.3.rs-8989018/v1

Amelioration of cyclophosphamide-induced myelosuppression by the methanol fraction of Talinum fruticosum

Sheneni, V. D., Anorue, E. C., Joshua, P. E., Ugwuene, F. O., & Agwu, L. O. (2026) · Drug and Chemical Toxicology · doi:10.1080/01480545.2026.2665456

Unexpected role of inflammatory signaling in hematopoietic stem cell development

He, Q., & Liu, F. (2015) · Current Opinion in Hematology · doi:10.1097/moh.0000000000000197 · Cited by 11

Inflammatory signals in HSPC development and homeostasis: Too much of a good thing?

Luis, T. C., Tremblay, C. S., Manz, M. G., North, T. E., King, K. Y., & Challen, G. A. (2016) · Experimental Hematology · doi:10.1016/j.exphem.2016.06.254 · Cited by 20

Impact of inflammation on early hematopoiesis and the microenvironment

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Regulation of stress-induced hematopoiesis

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Stress and Non-Stress Roles of Inflammatory Signals during HSC Emergence and Maintenance

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