The DOI matches its Crossref record; 95 of the 95 references it cites were found in a registry or an index.
Structural diversity of ABC transporters
Open accessAbstract
ATP-binding cassette (ABC) transporters form a large superfamily of ATP-dependent protein complexes that mediate transport of a vast array of substrates across membranes. The 14 currently available structures of ABC transporters have greatly advanced insight into the transport mechanism and revealed a tremendous structural diversity. Whereas the domains that hydrolyze ATP are structurally related in all ABC transporters, the membrane-embedded domains, where the substrates are translocated, adopt four different unrelated folds. Here, we review the structural characteristics of ABC transporters and discuss the implications of this structural diversity for mechanistic diversity.
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1 retracted
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Structure of P-Glycoprotein Reveals a Molecular Basis for Poly-Specific Drug Binding
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ABC transporters: the power to change
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P-glycoprotein: from genomics to mechanism
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Cited by
Mechanistic diversity in ATP-binding cassette (ABC) transporters.
Locher, K. P. (2016) · Nature Structural & Molecular Biology · doi:10.1038/nsmb.3216 · Cited by 804
Emran, T. B., Shahriar, A., Mahmud, A. R., Rahman, T., Abir, M. H., Siddiquee, M. F. R., Ahmed, H., Rahman, N., Nainu, F., Wahyudin, E., et al. (2022) · Frontiers in Oncology · doi:10.3389/fonc.2022.891652 · Cited by 606
Iron acquisition strategies of bacterial pathogens
Sheldon, J. R., Laakso, H. A., & Heinrichs, D. E. (2016) · Microbiology Spectrum · doi:10.1128/microbiolspec.vmbf-0010-2015 · Cited by 219
Genovese, I., Ilari, A., Assaraf, Y. G., Fazi, F., & Colotti, G. (2017) · Drug Resistance Updates · doi:10.1016/j.drup.2017.10.003 · Cited by 156
Cuyvers, E., De Roeck, A., Van den Bossche, T., Van Cauwenberghe, C., Bettens, K., Vermeulen, S., Mattheijssens, M., Peeters, K., Engelborghs, S., Vandenbulcke, M., et al. (2015) · The Lancet Neurology · doi:10.1016/s1474-4422(15)00133-7 · Cited by 152
Metadata
- Authors
- ter Beek, J., Guskov, A., & Slotboom, D. J.
- Venue
- Journal of General Physiology
- Publisher
- Rockefeller University Press
- Published
- 2014-03-17
- Volume
- 143
- Issue
- 4
- Pages
- 419-435
- ISSN
- 0022-1295 (ISSN-L)
- 1540-7748
- OpenAlex
- W2145796553
- Cited by
- 384
- References
- 95
- FWCI
- 14.94
- Type
- journal article
- Language
- en
- Open access
- hybrid
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- ter Beek, J., Guskov, A., & Slotboom, D. J. (2014). Structural diversity of ABC transporters. Journal of General Physiology. https://doi.org/10.1085/jgp.201411164
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
