Female-to-female transmission of human immunodeficiency virus.
Abstract
We describe a case of female-to-female transmission of human immunodeficiency virus (HIV). A 20-year-old African American woman with no obvious risk factors received a diagnosis of HIV infection, and the genotype of the infecting strain closely matched that of the strain infecting her openly bisexual female partner. The route of transmission was probably use of sex toys, used vigorously enough to cause exchange of blood-tinged body fluids.
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This possibility is most directly supported by reports of shared trichomonas infections and by concordant drug-resistance genotype testing and phylogenetic linkage analysis identifying HIV transmitted sexually between women.
“This possibility is most directly supported by reports of shared trichomonas infections (293,294) and by concordant drug-resistance genotype testing and phylogenetic linkage analysis identifying HIV transmitted sexually between women (295,296).”
From Sexually Transmitted Infections Treatment Guidelines, 2021 (2021) · cites this paper as [296]
Cites
Sexually transmitted infections and risk behaviours in women who have sex with women.
Fethers, K. (2000) · Sexually Transmitted Infections · doi:10.1136/sti.76.5.345 · Cited by 251 · see citing works
Bevier, P., Chiasson, M. A., Heffernan, R. T., & Castro, K. G. (1995) · American Journal of Public Health · doi:10.2105/ajph.85.10.1366 · Cited by 125 · see citing works
FEMALE-TO-FEMALE TRANSMISSION OF HIV
Monzon, O. T., & Capellan, J. B. (1987) · The Lancet · doi:10.1016/s0140-6736(87)93071-6 · Cited by 84 · see citing works
Rich, J. D., Buck, A., TUOMALA, R. E., & Kazanjian, P. H. (1993) · Clinical Infectious Diseases · doi:10.1093/clinids/17.6.1003 · Cited by 55 · see citing works
Lr, P., Doll, L., White, C., & Chu, S. (1992) · PubMed · Cited by 34 · see citing works
HIV infection in Romanian children: a call for antiretroviral therapy.
Leibovitz, E., Cooper, D., Orlow, S. J., Lawrence, R. M., Petrea, S., Jipa, G., Carausu, S., & Coman, G. (1993) · PubMed · Cited by 26 · see citing works
Lesbian sex and risk of HIV transmission.
Raiteri, R., Baussano, I., Giobbia, M., Fora, R., & Sinicco, A. (1998) · PubMed · Cited by 10 · see citing works
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Cited by
Sorted by citations
Sexually Transmitted Infections Treatment Guidelines, 2021
Workowski, K. A., Bachmann, L. H., Chan, P. A., Johnston, C. M., Muzny, C. A., Park, I., Reno, H., Zenilman, J. M., & Bolan, G. A. (2021) · MMWR. Recommendations and Reports · doi:10.15585/mmwr.rr7004a1 · Cited by 2,759 · see citing works
Sexually Transmitted Diseases Treatment Guidelines, 2010
Workowski, K., & BOLAN, G. A. (2011) · Annals of Emergency Medicine · doi:10.1016/j.annemergmed.2011.04.006 · Cited by 2,074 · see citing works
Marrazzo, J. M., Coffey, P. S., & Bingham, A. (2005) · PubMed · doi:10.1363/psrh.37.006.05 · Cited by 131 · see citing works
Reisner, S. L., Hughto, J. M. W., Mayer, K. H., & Mimiaga, M. J. (2013) · AIDS Care · doi:10.1080/09540121.2013.855701 · Cited by 122 · see citing works
Barriers to Infectious Disease Care among Lesbians1
Marrazzo, J. M. (2004) · Emerging infectious diseases · doi:10.3201/eid1011.040467 · Cited by 109 · see citing works
Sexually transmitted disease/HIV risk behaviour among women who have sex with women
Pinto, V. M., Tancredi, M. V., Neto, A. T., & Buchalla, C. M. (2005) · AIDS · doi:10.1097/01.aids.0000191493.43865.2a · Cited by 104 · see citing works
Doyal, L. (2009) · Culture Health & Sexuality · doi:10.1080/13691050802560336 · Cited by 94 · see citing works
The risk less known: female-to-male transgender persons’ vulnerability to HIV infection
Kenagy, G. P., & Hsieh, C. (2004) · AIDS Care · doi:10.1080/19540120512331325680 · Cited by 94 · see citing works
Some Considerations on Sexuality and Gender in the Context of AIDS
Dowsett, G. W. (2003) · Reproductive Health Matters · doi:10.1016/s0968-8080(03)02290-0 · Cited by 92 · see citing works
Sexually Transmitted Infections Among Women Who Have Sex With Women
Gorgos, L. M., & Marrazzo, J. M. (2011) · Clinical Infectious Diseases · doi:10.1093/cid/cir697 · Cited by 83 · see citing works
Sexual orientation and sexual health services utilization among women in the United States
Agénor, M., Muzny, C. A., Schick, V., Austin, E. L., & Potter, J. E. (2016) · Preventive Medicine · doi:10.1016/j.ypmed.2016.11.023 · Cited by 75 · see citing works
Muzny, C. A., Sunesara, I. R., Martin, D. H., & Mena, L. A. (2011) · Sexually Transmitted Diseases · doi:10.1097/olq.0b013e31822e6179 · Cited by 73 · see citing works
Prevalence and risk factors for infection with herpes simplex virus type-1 and -2 among lesbians.
Marrazzo, J. M., Stine, K., & Wald, A. (2003) · Sexually Transmitted Diseases · doi:10.1097/01.olq.0000091151.52656.e5 · Cited by 69 · see citing works
Singh, D., Fine, D. N., & Marrazzo, J. M. (2011) · American Journal of Public Health · doi:10.2105/ajph.2009.169631 · Cited by 69 · see citing works
Sandfort, T. G. M., Baumann, L. R. M., Matebeni, Z., Reddy, V., & Southey-Swartz, I. (2013) · PLoS ONE · doi:10.1371/journal.pone.0053552 · Cited by 67 · see citing works
Emerging Sexual Health Issues Among Women Who Have Sex with Women
Marrazzo, J. M., & Gorgos, L. M. (2012) · Current Infectious Disease Reports · doi:10.1007/s11908-012-0244-x · Cited by 64 · see citing works
Doull, M., Wolowic, J., Saewyc, E., Rosario, M., Prescott, T. L., & Ybarra, M. L. (2017) · Journal of Adolescent Health · doi:10.1016/j.jadohealth.2017.10.005 · Cited by 56 · see citing works
Sexual transmission of giardiasis: A neglected route of spread?
Escobedo, A. A., Almirall, P., Alfonso, M., Cimerman, S., & Chacín‐Bonilla, L. (2014) · Acta Tropica · doi:10.1016/j.actatropica.2013.12.025 · Cited by 51 · see citing works
Foxman, B., Aral, S. O., & Holmes, K. K. (2006) · Sexually Transmitted Diseases · doi:10.1097/01.olq.0000187210.53010.10 · Cited by 51 · see citing works
Muzny, C. A., Harbison, H. S., Pembleton, E. S., Hook, E. W., & Austin, E. L. (2013) · Sexual Health · doi:10.1071/sh12106 · Cited by 50 · see citing works
Likely female-to-female sexual transmission of HIV--Texas, 2012.
(2014) · PubMed Central · Cited by 46 · see citing works
Health Risk Behaviors in an Urban Sample of Young Women Who Have Sex with Women
Herrick, A. L., Matthews, A. K., & Garofalo, R. (2010) · Journal of Lesbian Studies · doi:10.1080/10894160903060440 · Cited by 40 · see citing works
Clinical use and implications of sexual devices and sexually explicit media
Dewitte, M. D., & Reisman, Y. (2021) · Nature Reviews Urology · doi:10.1038/s41585-021-00456-2 · Cited by 34 · see citing works
Invisible and at Risk: STDs Among Young Adult Sexual Minority Women in the United States
Lindley, L. L., Walsemann, K. M., & Carter, J. W. (2013) · Perspectives on Sexual and Reproductive Health · doi:10.1363/4506613 · Cited by 33 · see citing works
A Clinical Reference Guide on Sexual Devices for Obstetrician–Gynecologists
Rubin, E. S., Deshpande, N. A., Vasquez, P. J., & Spadt, S. K. (2019) · Obstetrics and Gynecology · doi:10.1097/aog.0000000000003262 · Cited by 31 · see citing works
Infectious Disease Issues in Underserved Populations
Grief, S. N., & Miller, J. P. (2017) · Primary Care Clinics in Office Practice · doi:10.1016/j.pop.2016.09.011 · Cited by 24 · see citing works
Young, R. M., Friedman, S. R., & Case, P. (2005) · Journal of Lesbian Studies · doi:10.1300/j155v09n03_10 · Cited by 24 · see citing works
Martin, E. G., Ansari, B., Hart-Malloy, R., Smith, D. K., Delaney, K. P., Gift, T. L., Berruti, A. A., Trigg, M., & Rosenberg, E. S. (2021) · PLoS ONE · doi:10.1371/journal.pone.0257583 · Cited by 23 · see citing works
Rullo, J., Lorenz, T. K., Ziegelmann, M. J., Meihofer, L., Herbenick, D., & Faubion, S. S. (2018) · Sexual & Relationship Therapy · doi:10.1080/14681994.2017.1419558 · Cited by 22 · see citing works
Engel, J. L., Fairley, C. K., Greaves, K. E., Vodstrcil, L. A., Ong, J. J., Bradshaw, C. S., Chen, M. Y., Phillips, T. R., & Chow, E. P. F. (2022) · Archives of Sexual Behavior · doi:10.1007/s10508-022-02311-w · Cited by 23 · see citing works
Gil‐Llario, M. D., Morell‐Mengual, V., García-Barba, M., García, J. E. N., & Ballester‐Arnal, R. (2022) · AIDS and Behavior · doi:10.1007/s10461-022-03752-z · Cited by 22 · see citing works
Pretreatment integrase strand transfer inhibitor resistance in North Carolina from 2010–2016
Menza, T. W., Billock, R. M., Samoff, E., Eron, J. J., & Dennis, A. M. (2017) · AIDS · doi:10.1097/qad.0000000000001611 · Cited by 22 · see citing works
Morillo, C. C. E., Botina, M. A., Solarte, M. A., Ramírez, I. H., Riascos, R. A., & Meyer, J. F. D. C. A. (2022) · Journal of Computational Biology · doi:10.1089/cmb.2021.0323 · Cited by 21 · see citing works
Lindley, L. L., Kerby, M. B., Nicholson, T. J., & Lü, N. (2007) · Journal of LGBT Health Research · doi:10.1080/15574090802093323 · Cited by 21 · see citing works
Dangerous Assumptions: Lesbians and Sexual Death
Marrazzo, J. M. (2005) · Sexually Transmitted Diseases · doi:10.1097/01.olq.0000175368.82940.61 · Cited by 21 · see citing works
Desir, F. A., Lesko, C. R., Moore, R. D., Horberg, M. A., Wong, C., Crane, H. M., Silverberg, M. J., Thorne, J. E., Rachlis, B., Rabkin, C. S., et al. (2018) · Clinical Infectious Diseases · doi:10.1093/cid/ciy556 · Cited by 19 · see citing works
Women Who have Sex with Women in the Global HIV Pandemic
Lenke, K., & Piehl, M. (2009) · Development · doi:10.1057/dev.2008.77 · Cited by 19 · see citing works
Kaida, A., Patterson, S., Carter, A., Loutfy, M. R., Ding, E., Sereda, P., Webster, K., Pick, N., Kestler, M., & de Pokomandy, A. (2017) · Perspectives on Sexual and Reproductive Health · doi:10.1363/psrh.12046 · Cited by 17 · see citing works
Marrazzo, J. M., Coffey, P. S., & Bingham, A. (2005) · Perspectives on Sexual and Reproductive Health · doi:10.1363/370605 · Cited by 17 · see citing works
Pour une promotion de la santé lesbienne : état des lieux des recherches, enjeux et propositions
Genon, C., Chartrain, C., & Delebarre, C. (2009) · Genre sexualité & société · doi:10.4000/gss.951 · Cited by 15 · see citing works
Sexually Transmitted Infections and Associated Conditions Among Women Who Have Sex with Women
Singh, D., & Marrazzo, J. M. (2009) · The Open Infectious Diseases Journal · doi:10.2174/1874279301004010128 · Cited by 12 · see citing works
Sexual behaviors of women who have sex with women: A qualitative explorative study
Emetu, R. E., Hernandez, E. N., Calleros, L., & Missari, S. (2022) · Sexual and Gender Diversity in Social Services · doi:10.1080/10538720.2022.2044952 · Cited by 11 · see citing works
Molin, S.-B., de Blasio, B. F., & Olsen, A. O. (2016) · Sexual Health · doi:10.1071/sh15193 · Cited by 11 · see citing works
Teti, M., Bowleg, L., Rubinstein, S., Lloyd, L., Berhane, Z., & Gold, M. J. (2007) · Journal of LGBT Health Research · doi:10.1080/15574090802226592 · Cited by 10 · see citing works
Teti, M., & Bowleg, L. (2011) · Sexual and Gender Diversity in Social Services · doi:10.1080/10538720.2010.538009 · Cited by 10 · see citing works
Muzny, C. A., Kapil, R., Austin, E. L., Hook, E. W., & Geisler, W. M. (2014) · Sexual Health · doi:10.1071/sh14181 · Cited by 8 · see citing works
HIV/AIDS Mathematical Model of Triangle Transmission
Morillo, C. C. E., & Meyer, J. F. D. C. A. (2022) · Viruses · doi:10.3390/v14122749 · Cited by 8 · see citing works
Health concerns of sexual minority adolescent girls
Brown, J. D., & Melchiono, M. W. (2006) · Current Opinion in Pediatrics · doi:10.1097/01.mop.0000236382.41531.c7 · Cited by 8 · see citing works
Palma, D. M., & Orcasita, L. T. (2017) · Interface - Comunicação Saúde Educação · doi:10.1590/1807-57622016.0790 · Cited by 8 · see citing works
Visual Mining of Epidemic Networks
de Arazoza, H., Fabrice Rossi, A., Tran, V. C., de Arazoza, H., Tran, V. C., & Mining, T. V. (2011) · Cited by 8 · see citing works
HIV and STD Prevention Needs of Bisexual Women: Results from Projet Polyvalence
Namaste, V., Vukov, T., Saghie, N., Jean-Gilles, J., Lafreniére, M., Leclerc, N., & Monette, A. (2007) · Canadian Journal of Communication · doi:10.22230/cjc.2007v32n3a1871 · Cited by 6 · see citing works
“La solución es la tijera”: Programa de Salud Sexual para Mujeres Lesbianas y Bisexuales
Palma, D. M., & Orcasita, L. T. (2018) · Psicologia Teoria e Pesquisa · doi:10.1590/0102.3772e34419 · Cited by 6 · see citing works
Marrazzo, J. M., Coffey, P. S., & Bingham, A. (2005) · Perspectives on Sexual and Reproductive Health · doi:10.1111/j.1931-2393.2005.tb00035.x · Cited by 6 · see citing works
Promoting sexual health in women who have sex with women
Ripley, V. (2011) · Nursing Standard · doi:10.7748/ns.25.51.41.s48 · Cited by 5 · see citing works
Women of Color and HIV/AIDS Epidemiology, Clinical Aspects, and Management
Ojikutu, B. O., Stone, V. E., & Bardeguez, A. D. (2009) · Springer eBooks · doi:10.1007/978-0-387-98152-9_6 · Cited by 5 · see citing works
STIs Among Women Who Have Sex with Women
Gorgos, L. M., & Marrazzo, J. M. (2017) · Springer eBooks · doi:10.1007/978-3-319-56694-8_13 · Cited by 5 · see citing works
La santé sexuelle des hommes trans : entre problèmes de catégorisation et invisibilisation
Rivest, P. (2023) · Santé Publique · doi:10.3917/spub.hs2.0037 · Cited by 5 · see citing works
Taylor, E., Jantzen, A., & Clow, B. (2013) · Cited by 4 · see citing works
Sexual Behavior in Sexual Minority Women and Connections with Discrimination
Smith, E. R., Perrin, P. B., & Rabinovitch, A. E. (2017) · Sexuality Research and Social Policy · doi:10.1007/s13178-017-0293-x · Cited by 3 · see citing works
Infectious Disease Issues in Underserved Populations
Grief, S. N., & Miller, J. P. (2018) · Physician Assistant Clinics · doi:10.1016/j.cpha.2018.08.006 · Cited by 3 · see citing works
Konan, Y. E. D., Dagnan, N. S., Tetchi, E. O., Aké, O., Tiembré, I., Zengbé, P., Ekou, F. K., Sable, P. S., Kpebo, D. O., Saraka, K. W. O., et al. (2014) · Bulletin de la Société de pathologie exotique · doi:10.1007/s13149-014-0382-5 · Cited by 3 · see citing works
Understanding and Reducing Risks via Infection in LBT Women
Tracy, J. K. (2015) · Springer eBooks · doi:10.1007/978-3-319-15057-4_3 · Cited by 2 · see citing works
Enhancing Women’s Sexual Health: Prevention Measures in Diverse Populations of Women
Marrazzo, J. M. (2012) · Springer eBooks · doi:10.1007/978-1-4614-4526-5_11 · Cited by 2 · see citing works
Visual Mining of Epidemic Networks
Clémençon, S., de Arazoza, H., Fabrice Rossi, A., & Tran, V. C. (2011) · Lecture notes in computer science · doi:10.1007/978-3-642-21498-1_35 · Cited by 2 · see citing works
O’Connor, C. A., O’Connor, M. B., Clancy, J., & Ryan, A. (2009) · International Journal of STD & AIDS · doi:10.1258/ijsa.2009.009171 · Cited by 2 · see citing works
Carrick, K. R. (2010) · D-Scholarship@Pitt (University of Pittsburgh) · Cited by 2 · see citing works
Sexually Transmitted Diseases Associated with Women Who Have Sex with Women
Bartzatt, R. (2014) · International STD Research & Reviews · doi:10.9734/isrr/2014/8931 · Cited by 2 · see citing works
Frost, D. M. (2019) · Cited by 2 · see citing works
IST/HIV/AIDS: ESTRATÉGIAS DE PREVENÇÃO PARA MULHERES QUE FAZEM SEXO COM MULHERES
dos Santos, J. K. P. F., de Almeida, L. C. G., de Oliveira, T. F., Silva, R. D. O., Anastácio, Z. F. C., de Sousa, A. R., Couto, T. M., & Santos, R. D. S. (2024) · Enfermagem em Foco · doi:10.21675/2357-707x.2024.v15.e-202414supl2 · Cited by 1 · see citing works
An overview of the Human Immunodeficiency Virus (HIV)
Renshaw, J. (2016) · Journal of Paramedic Practice · doi:10.12968/jpar.2016.8.10.507 · Cited by 1 · see citing works
Facchini, R. (2008) · doi:10.47749/t/unicamp.2008.427789 · Cited by 1 · see citing works
We women are women with a different manner
Henderson, J., Cloete, A., & van Zyl, M. (2011)
"We women are women with a different manner": sexual health of WSW in four Western Cape communities
Henderson, J., Cloete, A., & van Zyl, M. (2011)
Pallangyo, P., Millinga, J., Swai, H., Hemed, N. R., Mkojera, Z., Mosha, S., Granima, M., Bhalia, S. V., Gandye, Y., & Janabi, M. (2021) · Journal of Medical Case Reports · doi:10.1186/s13256-021-02918-y
Guterres, K. L. D. S., Machado, L. F. A., Ishak, R., Miranda, R. D. N. A., Castro, A. J. D. O., Azevedo, V. N., Vallinoto, A. C. R., Feitosa, R. N. M., de Souza, R. G., Vieira, C. R. S. F., et al. (2021) · Editora Reflexão Acadêmica eBooks · doi:10.51497/reflex.0000100
Dennert, G. (2005) · doi:10.1007/978-3-86226-360-8_6
Interamericana, U. A., Gabini, S., Argentina., Consejo Nacional de Investigaciones Científicas y Técnicas, A., Castro, L., Argentina., U. A. I., Coldeira, M. F., Argentina., U. A. I., Consejo Nacional de Investigaciones Científicas y Técnicas, A., Cuenya, L., et al. (2024) · Población & Sociedad · doi:10.19137/pys-2024-310207
Hobson, E. K. (2025) · Signs · doi:10.1086/737474
- Authors
- Kwakwa, H. A., & Ghobrial, M. W.
- Affiliations
- Mercy Catholic Medical Center (US)
- Mercy Fitzgerald Hospital (US)
- Corresponding author
- Kwakwa, Helena A.
- ORCID
- Kwakwa, Helena A.
- Venue
- Clinical Infectious Diseases
- Publisher
- Oxford University Press (OUP)
- Published
- 2003-02
- Volume
- 36
- Issue
- 3
- Pages
- e40-e41
- ISSN
- 1058-4838 (ISSN-L)
- 1537-6591
- OpenAlex
- W2168606211
- Cited by
- 81
- References
- 7
- Citations by year
- 2025: 1 · 2024: 2 · 2023: 1 · 2022: 5 · 2021: 5 · 2019: 3 · 2018: 4 · 2017: 7 · 2016: 3 · 2015: 2 · 2014: 6 · 2013: 5 · 2012: 2
- FWCI
- 2.52
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Clinical Infectious Diseases (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Infectious Diseases › HIV/AIDS Research and Interventions
- Life Sciences › Immunology and Microbiology › Virology › HIV Research and Treatment
- Health Sciences › Medicine › Epidemiology › HIV, Drug Use, Sexual Risk
- Keywords
- HIV infection, bisexual women, sex toys
- MeSH terms
- Adult, Bisexuality, Female, Genotype, HIV, Humans, HIV Infections
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