Cited by 208Antimicrobial Resistance in Staphylococcusvaccines and immunoinformatics approachesBiochemical and Structural Characterization

The DOI matches its Crossref record; 50 of the 50 references it cites were found in a registry or an index.

Identification of In Vivo–Expressed Antigens of Staphylococcus aureus and Their Use in Vaccinations for Protection against Nasal Carriage

Clarke, Simon R., Brummell, Kirsten J., Horsburgh, Malcolm J., McDowell, Philip W., Mohamad, Sharifah A. Syed, Stapleton, Melanie R., Acevedo, Jorge, Read, Robert C., Day, Nicholas P. J., Peacock, Sharon J., Mond, James J., Kokai‐Kun, John F., Foster, Simon J.·2006·The Journal of Infectious Diseases

DOI 10.1086/501471

Open this paper in CoChat — free account

Abstract

A spectrum of in vivo-expressed Staphylococcus aureus antigens was identified by probing bacteriophage expression libraries of S. aureus with serum samples from infected and uninfected individuals. Eleven recombinant antigenic proteins were produced, and specific antibody titers in a large collection of human serum samples were determined. Significantly increased concentrations of reactive immunoglobulin G (IgG) to 7 antigens were found in serum samples from ill individuals, compared with those in healthy individuals. Significantly higher concentrations of reactive IgG to 4 antigens, including iron-responsive surface determinant (Isd) A and IsdH, were found in serum samples from healthy individuals who were not nasal carriers of S. aureus, compared with those in healthy carriers. Vaccination of cotton rats with IsdA or IsdH protected against nasal carriage. Also, IsdA is involved in adherence of S. aureus to human desquamated nasal epithelial cells and is required for nasal colonization in the cotton rat model. Thus, vaccination with these antigens may prevent S. aureus carriage and reduce the prevalence of human disease.

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

Integrity signals

Registry

Crossref · 10.1086/501471

Cites

50 of 50 references verified0 citation errors · 0 not checkable

Statistics

Claims the paper makes

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

Self-check

Percentages, sums and reported differences re-computed from the paper’s own numbers.

The self-check needs the paper’s full text.

Principles and Practice of Infectious Diseases.
(1991) · Annals of Internal Medicine · doi:10.7326/0003-4819-114-9-818_5 · Cited by 12,045
Bacterial iron homeostasis
Andrews, S. C., Robinson, A. K., & Rodríguez-Quiñones, F. (2003) · FEMS Microbiology Reviews · doi:10.1016/s0168-6445(03)00055-x · Cited by 2,702
Nasal Carriage as a Source of Staphylococcus aureus Bacteremia
von Eiff, C., Becker, K., Machka, K., Stammer, H., & Peters, G. (2001) · New England Journal of Medicine · doi:10.1056/nejm200101043440102 · Cited by 1,984
Whole genome sequencing of meticillin-resistant Staphylococcus aureus
Kuroda, M., Ohta, T., Uchiyama, I., Baba, T., Yuzawa, H., Kobayashi, I., Cui, L., Oguchi, A., Aoki, K.-I., Nagai, Y., et al. (2001) · The Lancet · doi:10.1016/s0140-6736(00)04403-2 · Cited by 1,950
Identification of Vaccine Candidates Against Serogroup B Meningococcus by Whole-Genome Sequencing
Pizza, M., Scarlato, V., Masignani, V., Giuliani, M. M., Aricò, B., Comanducci, M., Jennings, G. T., Baldi, L., Bartolini, E., Capecchi, B., et al. (2000) · Science · doi:10.1126/science.287.5459.1816 · Cited by 1,403
An overview of nosocomial infections, including the role of the microbiology laboratory
Emori, T. G., & Gaynes, R. P. (1993) · Clinical Microbiology Reviews · doi:10.1128/cmr.6.4.428 · Cited by 1,262
Risk and outcome of nosocomial Staphylococcus aureus bacteraemia in nasal carriers versus non-carriers
Wertheim, H. F. L., Vos, M. D., Ott, A., van Belkum, A., Voß, A., Kluytmans, J. A. J. W., van Keulen, P. H. J., Vandenbroucke‐Grauls, C. M. J. E., Meester, M. H. M., & Verbrugh, H. A. (2004) · The Lancet · doi:10.1016/s0140-6736(04)16897-9 · Cited by 891
Properties of a cryptic high-frequency transducing phage in Staphylococcus aureus
Novick, R. P. (1967) · Virology · doi:10.1016/0042-6822(67)90105-5 · Cited by 745
σ B Modulates Virulence Determinant Expression and Stress Resistance: Characterization of a Functional rsbU Strain Derived from Staphylococcus aureus 8325-4
Horsburgh, M. J., Aish, J., White, I. J., Shaw, L., Lithgow, J. K., & Foster, S. J. (2002) · Journal of Bacteriology · doi:10.1128/jb.184.19.5457-5467.2002 · Cited by 699
Self-citation
Staphylococcal Coagulase: Mode of Action and Antigenicity
Duthie, E. S., & Lorenz, L. (1952) · Microbiology · doi:10.1099/00221287-6-1-2-95 · Cited by 623

Show all 49 references

Research works printed but not linked: 4

Marchese A, Schito GC, Debbia EA. Emergence of drug-resistant gram- positive pathogenic bacteria. J Chemother 2000; 12:459-62.
Bredius RGM, de Vries CE, Troelstra A, et al. Phagocytosis of Staph- ylococcus aureus and Haemophilus influenzae type B opsonized with polyclonal human IgG1 and IgG2 antibodies. J Immunol 1993; 151: 1463-72.
Kauppi M, Saarinen L, Ka ¨yhty H. Anti-capsular polysaccharide anti- bodies reduce nasopharyngeal colonization by Haemophilus influenzae type b in infant rats. J Infect Dis 1993; 167:365-71.
Andrews SC, Robinson AK, Rodrı ´guez-Quin ˜ones F. Bacterial iron ho- meostasis. FEMS Microbiol Rev 2003; 27:215-37.

Sorted by citations

Adhesion, invasion and evasion: the many functions of the surface proteins of Staphylococcus aureus
Foster, T. J., Geoghegan, J. A., Ganesh, V. K., & Höök, M. (2013) · Nature Reviews Microbiology · doi:10.1038/nrmicro3161 · Cited by 1,606
Atopic dermatitis: a disease of altered skin barrier and immune dysregulation
Boguniewicz, M., & Leung, D. Y. M. (2011) · Immunological Reviews · doi:10.1111/j.1600-065x.2011.01027.x · Cited by 1,100
Staphylococcus aureus Nasal Colonization: An Update on Mechanisms, Epidemiology, Risk Factors, and Subsequent Infections
Sakr, A., Brégeon, F., Mège, J., Rolain, J., & Blin, O. (2018) · Frontiers in Microbiology · doi:10.3389/fmicb.2018.02419 · Cited by 598
Staphylococcus aureus and Atopic Dermatitis: A Complex and Evolving Relationship
Geoghegan, J. A., Irvine, A. D., & Foster, T. J. (2017) · Trends in Microbiology · doi:10.1016/j.tim.2017.11.008 · Cited by 533
Scenery of Staphylococcus Implant Infections in Orthopedics
Montanaro, L., Speziale, P., Campoccia, D., Ravaioli, S., Cangini, I., Pietrocola, G., Giannini, S., & Arciola, C. R. (2011) · Future Microbiology · doi:10.2217/fmb.11.117 · Cited by 368
Catalase (KatA) and Alkyl Hydroperoxide Reductase (AhpC) Have Compensatory Roles in Peroxide Stress Resistance and Are Required for Survival, Persistence, and Nasal Colonization in Staphylococcus aureus
Cosgrove, K., Coutts, G., Jonsson, I.-M., Tarkowski, A., Kokai-Kun, J. F., Mond, J. J., & Foster, S. J. (2007) · Journal of Bacteriology · doi:10.1128/jb.01524-06 · Cited by 334
Self-citation
The role of Staphylococcus aureus surface protein SasG in adherence and biofilm formation
Corrigan, R. M., Rigby, D., Handley, P. S., & Foster, T. J. (2007) · Microbiology · doi:10.1099/mic.0.2007/006676-0 · Cited by 335
Recent insights into atopic dermatitis and implications for management of infectious complications
Boguniewicz, M., & Leung, D. Y. M. (2010) · Journal of Allergy and Clinical Immunology · doi:10.1016/j.jaci.2009.11.027 · Cited by 334
Staphylococcus aureus IsdB Is a Hemoglobin Receptor Required for Heme Iron Utilization
Torres, V. J., Pishchany, G., Humayun, M., Schneewind, O., & Skaar, E. P. (2006) · Journal of Bacteriology · doi:10.1128/jb.01335-06 · Cited by 302
Recent developments in understanding the iron acquisition strategies of gram positive pathogens
Sheldon, J. R., & Heinrichs, D. E. (2015) · FEMS Microbiology Reviews · doi:10.1093/femsre/fuv009 · Cited by 272
Staphylococcus aureus Colonization: Modulation of Host Immune Response and Impact on Human Vaccine Design
Brown, A. F., Leech, J. M., Rogers, T. R., & McLoughlin, R. M. (2014) · Frontiers in Immunology · doi:10.3389/fimmu.2013.00507 · Cited by 265
Cell wall peptidoglycan architecture in Bacillus subtilis
Hayhurst, E. J., Kailas, L., Hobbs, J. K., & Foster, S. J. (2008) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0804138105 · Cited by 244
Self-citation
Effect of filaggrin breakdown products on growth of and protein expression by Staphylococcus aureus
Miajlović, H., Fallon, P. G., Irvine, A. D., & Foster, T. J. (2010) · Journal of Allergy and Clinical Immunology · doi:10.1016/j.jaci.2010.09.015 · Cited by 242
Iron acquisition strategies of bacterial pathogens
Sheldon, J. R., Laakso, H. A., & Heinrichs, D. E. (2016) · Microbiology Spectrum · doi:10.1128/microbiolspec.vmbf-0010-2015 · Cited by 219
The Staphylococcus aureus surface protein IsdA mediates resistance to innate defenses of human skin
Clarke, S. R., Mohamed, R., Bian, L., Routh, A. F., Kokai-Kun, J. F., Mond, J. J., Tarkowski, A., & Foster, S. J. (2007) · Cell Host & Microbe · doi:10.1016/j.chom.2007.04.005 · Cited by 225
Self-citation
Surface proteins that promote adherence of Staphylococcus aureusto human desquamated nasal epithelial cells
Corrigan, R. M., Miajlovic, H., & Foster, T. J. (2009) · BMC Microbiology · doi:10.1186/1471-2180-9-22 · Cited by 226
Antimicrobial Agents in Orthopaedic Surgery
Trampuž, A., & Zimmerli, W. (2006) · Drugs · doi:10.2165/00003495-200666080-00005 · Cited by 225
Identification of Staphylococcus aureus Proteins Recognized by the Antibody-Mediated Immune Response to a Biofilm Infection
Brady, R. A., Leid, J. G., Camper, A. K., Costerton, J. W., & Shirtliff, M. E. (2006) · Infection and Immunity · doi:10.1128/iai.00392-06 · Cited by 219
Differential Expression and Roles of Staphylococcus aureus Virulence Determinants during Colonization and Disease
Jenkins, A. L., Diep, B. A., Mai, T. T., Vo, N. H., Warrener, P., Suzich, J., Stover, C. K., & Sellman, B. R. (2015) · mBio · doi:10.1128/mbio.02272-14 · Cited by 202
Staphylococcus aureus colonisation and strategies for decolonisation
Piewngam, P., & Otto, M. J. (2024) · The Lancet Microbe · doi:10.1016/s2666-5247(24)00040-5 · Cited by 192
Anti-Staphylococcal Humoral Immune Response in Persistent Nasal Carriers and Noncarriers ofStaphylococcus aureus
Verkaik, N. J., de Vogel, C. P., Boelens, H. A. M., Grumann, D., Hoogenboezem, T., Vink, C., Hooijkaas, H., Foster, T. J., Verbrugh, H. A., van Belkum, A., et al. (2009) · The Journal of Infectious Diseases · doi:10.1086/596743 · Cited by 178
Global analysis of community-associated methicillin-resistant Staphylococcus aureus exoproteins reveals molecules produced in vitro and during infection
Burlak, C., Hammer, C. H., Robinson, M.-A., Whitney, A. R., Mcgavin, M. J., Kreiswirth, B. N., & DeLeo, F. R. (2007) · Cellular Microbiology · doi:10.1111/j.1462-5822.2006.00858.x · Cited by 177
Haem recognition by a Staphylococcus aureus NEAT domain
Grigg, J. C., Vermeiren, C. L., Heinrichs, D. E., & Murphy, M. E. P. (2007) · Molecular Microbiology · doi:10.1111/j.1365-2958.2006.05502.x · Cited by 166
Inferring Reasons for the Failure of Staphylococcus aureus Vaccines in Clinical Trials
Bagnoli, F., Bertholet, S., & Grandi, G. (2012) · Frontiers in Cellular and Infection Microbiology · doi:10.3389/fcimb.2012.00016 · Cited by 172
Nasal Colonisation by Staphylococcus aureus Depends upon Clumping Factor B Binding to the Squamous Epithelial Cell Envelope Protein Loricrin
Mulcahy, M. E., Geoghegan, J. A., Monk, I. R., O’Keeffe, K. M., Walsh, E. J., Foster, T. J., & McLoughlin, R. M. (2012) · PLoS Pathogens · doi:10.1371/journal.ppat.1003092 · Cited by 170
Structural biology of heme binding in the Staphylococcus aureus Isd system
Grigg, J. C., Ukpabi, G., Gaudin, C. F. M., & Murphy, M. E. P. (2010) · Journal of Inorganic Biochemistry · doi:10.1016/j.jinorgbio.2009.09.012 · Cited by 169
Staphylococcus aureus Toxins and Diabetic Foot Ulcers: Role in Pathogenesis and Interest in Diagnosis
Dunyach‐Remy, C., Essebe, C. N., Sotto, A., & Lavigne, J. (2016) · Toxins · doi:10.3390/toxins8070209 · Cited by 184
A review on nanosystems as an effective approach against infections of Staphylococcus aureus
Zhou, K., Li, C., Chen, D., Pan, Y., Tao, Y., Qu, W., Liu, Z., Wang, X., & Xie, S. (2018) · International Journal of Nanomedicine · doi:10.2147/ijn.s169935 · Cited by 164
Characterization of IsaA and SceD, Two Putative Lytic Transglycosylases of Staphylococcus aureus
Stapleton, M. R., Horsburgh, M. J., Hayhurst, E. J., Wright, L., Jonsson, I., Tarkowski, A., Kokai‐Kun, J. F., Mond, J. J., & Foster, S. J. (2007) · Journal of Bacteriology · doi:10.1128/jb.00734-07 · Cited by 164
Self-citation
Proteomics uncovers extreme heterogeneity in the Staphylococcus aureus exoproteome due to genomic plasticity and variant gene regulation
Ziebandt, A., Kusch, H., Degner, M., Jaglitz, S., Sibbald, M. J. J. B., Arends, J. P., Chlebowicz, M. A., Albrecht, D., Pantůček, R., Doškař, J., et al. (2010) · PROTEOMICS · doi:10.1002/pmic.200900313 · Cited by 158
Metal ion acquisition in Staphylococcus aureus: overcoming nutritional immunity
Cassat, J. E., & Skaar, E. P. (2012) · Seminars in Immunopathology · doi:10.1007/s00281-011-0294-4 · Cited by 155
Staphylococcus aureus determinants for nasal colonization
Weidenmaier, C., Goerke, C., & Wolz, C. (2012) · Trends in Microbiology · doi:10.1016/j.tim.2012.03.004 · Cited by 153
Surface Proteins ofStaphylococcus aureus
Foster, T. J. (2019) · Microbiology Spectrum · doi:10.1128/microbiolspec.gpp3-0046-2018 · Cited by 178
Host–pathogen interactions between the skin and Staphylococcus aureus
Krishna, S. M., & Miller, L. S. (2011) · Current Opinion in Microbiology · doi:10.1016/j.mib.2011.11.003 · Cited by 152
The Role of Staphylococcus aureus Virulence Factors in Skin Infection and Their Potential as Vaccine Antigens
Lacey, K. A., Geoghegan, J. A., & McLoughlin, R. M. (2016) · Pathogens · doi:10.3390/pathogens5010022 · Cited by 155
Colonization and infection of the human host by staphylococci: adhesion, survival and immune evasion
Foster, T. J. (2009) · Veterinary Dermatology · doi:10.1111/j.1365-3164.2009.00825.x · Cited by 144
Molecular Characterization of a Novel Staphylococcus Aureus Surface Protein (SasC) Involved in Cell Aggregation and Biofilm Accumulation
Schroeder, K., Jularic, M., Horsburgh, S. M., Nina, H., Neumann, C., Bertling, A., Schulte, A., Foster, S. J., Kehrel, B. E., Peters, G., et al. (2009) · PLoS ONE · doi:10.1371/journal.pone.0007567 · Cited by 143
Self-citation
Temporal Expression of Adhesion Factors and Activity of Global Regulators during Establishment ofStaphylococcus aureusNasal Colonization
Burian, M., Rautenberg, M., Kohler, T. P., Fritz, M., Krismer, B., Unger, C., Hoffmann, W. H., Peschel, A., Wolz, C., & Goerke, C. (2010) · The Journal of Infectious Diseases · doi:10.1086/651619 · Cited by 140
Colonization and Infection of the Skin by S. aureus: Immune System Evasion and the Response to Cationic Antimicrobial Peptides
Ryu, S., Song, P. I., Seo, C., Cheong, H., & Park, Y. (2014) · International Journal of Molecular Sciences · doi:10.3390/ijms15058753 · Cited by 146
Efficacy of Staphylococcus aureus vaccines for bovine mastitis: A systematic review
Pereira, U. D. P., de Oliveira, D. G. S., Mesquita, L. D. R., da Costa, G. M., & Pereira, L. J. (2010) · Veterinary Microbiology · doi:10.1016/j.vetmic.2010.10.003 · Cited by 130
Active Immunization with Extracellular Vesicles Derived from Staphylococcus aureus Effectively Protects against Staphylococcal Lung Infections, Mainly via Th1 Cell-Mediated Immunity
Choi, S. J., Kim, M.-H., Jeon, J., Kim, O. Y., Choi, Y., Seo, J., Hong, S., Lee, W. H., Jeon, S. G., Gho, Y. S., et al. (2015) · PLoS ONE · doi:10.1371/journal.pone.0136021 · Cited by 129
Vaccination and passive immunisation against Staphylococcus aureus
Schaffer, A. C., & Lee, J. C. (2008) · International Journal of Antimicrobial Agents · doi:10.1016/j.ijantimicag.2008.06.009 · Cited by 127
Structural and functional role of Staphylococcus aureus surface components recognizing adhesive matrix molecules of the host
Speziale, P., Pietrocola, G., Rindi, S., Provenzano, M., Provenza, G., Poto, A. D., Visai, L., & Arciola, C. R. (2009) · Future Microbiology · doi:10.2217/fmb.09.102 · Cited by 133
Crystal Structure of the Heme-IsdC Complex, the Central Conduit of the Isd Iron/Heme Uptake System in Staphylococcus aureus
Sharp, K. H., Schneider, S., Cockayne, A., & Paoli, M. (2007) · Journal of Biological Chemistry · doi:10.1074/jbc.m700234200 · Cited by 120
A Nasal Epithelial Receptor for Staphylococcus aureus WTA Governs Adhesion to Epithelial Cells and Modulates Nasal Colonization
Baur, S., Rautenberg, M., Faulstich, M., Grau, T., Severin, Y., Unger, C., Hoffmann, W. H., Rudel, T., Autenrieth, I. B., & Weidenmaier, C. (2014) · PLoS Pathogens · doi:10.1371/journal.ppat.1004089 · Cited by 117
Towards the immune proteome of Staphylococcus aureus – The anti-S. aureus antibody response
Holtfreter, S., Kolata, J., & Bröker, B. M. (2009) · International Journal of Medical Microbiology · doi:10.1016/j.ijmm.2009.10.002 · Cited by 117
Host–Bacterial Crosstalk Determines Staphylococcus aureus Nasal Colonization
Mulcahy, M. E., & McLoughlin, R. M. (2016) · Trends in Microbiology · doi:10.1016/j.tim.2016.06.012 · Cited by 121
Is there a future for a Staphylococcus aureus vaccine?
Proctor, R. A. (2011) · Vaccine · doi:10.1016/j.vaccine.2011.11.006 · Cited by 109
Differential roles of sortase-anchored surface proteins and wall teichoic acid in Staphylococcus aureus nasal colonization
Weidenmaier, C., Kokai‐Kun, J. F., Kulauzovic, E., Kohler, T. P., Thumm, G., Stoll, H., Götz, F., & Peschel, A. (2008) · International Journal of Medical Microbiology · doi:10.1016/j.ijmm.2007.11.006 · Cited by 113
Self-citation
Wall Teichoic Acid Glycosylation Governs Staphylococcus aureus Nasal Colonization
Winstel, V., Kühner, P., Salomon, F., Larsen, J., Skov, R. L., Hoffmann, W. H., Peschel, A., & Weidenmaier, C. (2015) · mBio · doi:10.1128/mbio.00632-15 · Cited by 105
Iron-Regulated Surface Determinant Protein A Mediates Adhesion of Staphylococcus aureus to Human Corneocyte Envelope Proteins
Clarke, S. R., Andre, G., Walsh, E. J., Dufrêne, Y. F., Foster, T. J., & Foster, S. J. (2009) · Infection and Immunity · doi:10.1128/iai.01304-08 · Cited by 105
Self-citation
Molecular imaging of glycan chains couples cell-wall polysaccharide architecture to bacterial cell morphology
Turner, R. D., Mesnage, S., Hobbs, J. K., & Foster, S. J. (2018) · Nature Communications · doi:10.1038/s41467-018-03551-y · Cited by 101
Self-citation
Staphylococcus aureus Manganese Transport Protein C Is a Highly Conserved Cell Surface Protein That Elicits Protective Immunity Against S. aureus and Staphylococcus epidermidis
Anderson, A. S., Scully, I. L., Timofeyeva, Y., Murphy, E., McNeil, L. K., Mininni, T., Nuñez, L., Carrière, M. B., Singer, C. L., Dilts, D. A., et al. (2012) · The Journal of Infectious Diseases · doi:10.1093/infdis/jis272 · Cited by 100
Host- and microbe determinants that may influence the success of S. aureus colonization
Johannessen, M., Sollid, J. E., & Hanssen, A.-M. (2012) · Frontiers in Cellular and Infection Microbiology · doi:10.3389/fcimb.2012.00056 · Cited by 100
Potentials of nanotechnology in treatment of methicillin-resistant Staphylococcus aureus
Gao, Y., Chen, Y., Cao, Y., Mo, A., & Peng, Q. (2020) · European Journal of Medicinal Chemistry · doi:10.1016/j.ejmech.2020.113056 · Cited by 101
Staphylococcal Vaccines and Immunotherapies
Schaffer, A. C., & Lee, J. C. (2009) · Infectious Disease Clinics of North America · doi:10.1016/j.idc.2008.10.005 · Cited by 98
The interaction between Staphylococcus aureus SdrD and desmoglein 1 is important for adhesion to host cells
Askarian, F., Ajayi, C., Hanssen, A.-M., van Sorge, N. M., Pettersen, I., Diep, D. B., Ericson, J. U., & Johannessen, M. (2016) · Scientific Reports · doi:10.1038/srep22134 · Cited by 104
Bacterial Cell Enlargement Requires Control of Cell Wall Stiffness Mediated by Peptidoglycan Hydrolases
Wheeler, R., Turner, R. D., Bailey, R. G., Salamaga, B., Mesnage, S., Mohamad, S. A. S., Hayhurst, E. J., Horsburgh, M. J., Hobbs, J. K., & Foster, S. J. (2015) · mBio · doi:10.1128/mbio.00660-15 · Cited by 96
Self-citation
Structural and Biochemical Characterization of Staphylococcus aureus Clumping Factor B/Ligand Interactions
Ganesh, V. K., Barbu, E. M., Deivanayagam, C. C. S., Le, B. V., Anderson, A. S., Matsuka, Y. V., Lin, S. L., Foster, T. J., Narayana, S. V. L., & Höök, M. (2011) · Journal of Biological Chemistry · doi:10.1074/jbc.m110.217414 · Cited by 91
Staphylococcus aureusantigens and challenges in vaccine development
Middleton, J. R. (2008) · Expert Review of Vaccines · doi:10.1586/14760584.7.6.805 · Cited by 90
Biofilm Matrix Exoproteins Induce a Protective Immune Response against Staphylococcus aureus Biofilm Infection
Gil, C., Solano, C., Burgui, S., Latasa, C., García, B., Toledo‐Arana, A., Lasa, Í., & Valle, J. (2013) · Infection and Immunity · doi:10.1128/iai.01419-13 · Cited by 88
Hemoglobin Promotes Staphylococcus aureus Nasal Colonization
Pynnonen, M. A., Stephenson, R. E., Schwartz, K., Hernandez, M., & Boles, B. R. (2011) · PLoS Pathogens · doi:10.1371/journal.ppat.1002104 · Cited by 84
Heterogeneity of the humoral immune response following Staphylococcus aureus bacteremia
Verkaik, N. J., Boelens, H. A. M., de Vogel, C. P., Tavakol, M., Bode, L. G. M., Verbrugh, H. A., van Belkum, A., & van Wamel, W. J. B. (2010) · European Journal of Clinical Microbiology & Infectious Diseases · doi:10.1007/s10096-010-0888-0 · Cited by 83
Staphylococcus aureus-Associated Skin and Soft Tissue Infections: Anatomical Localization, Epidemiology, Therapy and Potential Prophylaxis
Olaniyi, R., Pozzi, C., Grimaldi, L., & Bagnoli, F. (2016) · Current topics in microbiology and immunology · doi:10.1007/82_2016_32 · Cited by 85
Novel targeted immunotherapy approaches for staphylococcal infection
Otto, M. J. (2010) · Expert Opinion on Biological Therapy · doi:10.1517/14712598.2010.495115 · Cited by 85
Proteomics-Based Identification of Anchorless Cell Wall Proteins as Vaccine Candidates againstStaphylococcus aureus
Glowalla, E., Tosetti, B., Krönke, M., & Krut, O. (2009) · Infection and Immunity · doi:10.1128/iai.00617-08 · Cited by 83
Staphylococcus aureus keratinocyte invasion is dependent upon multiple high-affinity fibronectin-binding repeats within FnBPA
Edwards, A. M., Potter, U., Meenan, N. A. G., Potts, J. R., & Massey, R. C. (2011) · PLoS ONE · doi:10.1371/journal.pone.0018899 · Cited by 80
Induction of antibodies by Staphylococcus aureus nasal colonization in young children
Verkaik, N. J., Lebon, A., de Vogel, C. P., Hooijkaas, H., Verbrugh, H. A., Jaddoe, V. W. V., Albert Hofman, D., Moll, H. A., van Belkum, A., & van Wamel, W. J. B. (2009) · Clinical Microbiology and Infection · doi:10.1111/j.1469-0691.2009.03073.x · Cited by 76
IsdA Protects Staphylococcus aureus against the Bactericidal Protease Activity of Apolactoferrin
Clarke, S. R., & Foster, S. J. (2008) · Infection and Immunity · doi:10.1128/iai.01530-07 · Cited by 75
Self-citation
Sortases, Surface Proteins, and Their Roles in Staphylococcus aureus Disease and Vaccine Development
Schneewind, O., & Missiakas, D. M. (2019) · Microbiology Spectrum · doi:10.1128/microbiolspec.psib-0004-2018 · Cited by 75
Characterization of the Heme Binding Properties of Staphylococcus aureus IsdA
Vermeiren, C. L., Pluym, M., Mack, J. P., Heinrichs, D. E., & Stillman, M. J. (2006) · Biochemistry · doi:10.1021/bi0607711 · Cited by 74
Distinctive patterns in the human antibody response to Staphylococcus aureus bacteremia in carriers and non‐carriers
Kolata, J., Bode, L. G. M., Holtfreter, S., Steil, L., Kusch, H., Holtfreter, B., Albrecht, D., Hecker, M., Engelmann, S., van Belkum, A., et al. (2011) · PROTEOMICS · doi:10.1002/pmic.201000760 · Cited by 73
Immune evasion by Staphylococcus aureus conferred by iron-regulated surface determinant protein IsdH
Visai, L., Yanagisawa, N., Josefsson, E., Tarkowski, A., Pezzali, I., Rooijakkers, S. H. M., Foster, T. J., & Speziale, P. (2009) · Microbiology · doi:10.1099/mic.0.025684-0 · Cited by 73
Immune control of Staphylococcus aureus – Regulation and counter-regulation of the adaptive immune response
Bröker, B. M., Holtfreter, S., & Bekeredjian‐Ding, I. (2013) · International Journal of Medical Microbiology · doi:10.1016/j.ijmm.2013.11.008 · Cited by 72
Haemophore functions revisited
Wandersman, C., & Delepelaire, P. (2012) · Molecular Microbiology · doi:10.1111/j.1365-2958.2012.08136.x · Cited by 70
Levels of Antibody against 11 Staphylococcus aureus Antigens in a Healthy Population
Colque‐Navarro, P., Jacobsson, G., Andersson, R., Flock, J., & Möllby, R. (2010) · Clinical and Vaccine Immunology · doi:10.1128/cvi.00506-09 · Cited by 70
Cell Wall-Anchored Surface Proteins of Staphylococcus aureus: Many Proteins, Multiple Functions
Geoghegan, J. A., & Foster, T. J. (2015) · Current topics in microbiology and immunology · doi:10.1007/82_2015_5002 · Cited by 72
Generation of a Novel Staphylococcus aureus Ghost Vaccine and Examination of Its Immunogenicity against Virulent Challenge in Rats
Vinod, N., Oh, S. J., Park, H. J., Koo, J. M., Choi, C. W., & Kim, S. C. (2015) · Infection and Immunity · doi:10.1128/iai.00009-15 · Cited by 66
Human Defensins: A Novel Approach in the Fight against Skin Colonizing Staphylococcus aureus
Scudiero, O., Brancaccio, M., Mennitti, C., Laneri, S., Lombardo, B., Biasi, M.-G. D., Gregorio, E. D., Pagliuca, C., Colicchio, R., Salvatore, P., et al. (2020) · Antibiotics · doi:10.3390/antibiotics9040198 · Cited by 68
Immunotherapeutic strategies to combat staphylococcal infections
Ohlsen, K., & Lorenz, U. (2010) · International Journal of Medical Microbiology · doi:10.1016/j.ijmm.2010.04.015 · Cited by 61
A Diagnostic Serum Antibody Test for Patients With Staphylococcus aureus Osteomyelitis
Nishitani, K., Beck, C. A., Rosenberg, A. F., Kates, S. L., Schwarz, E. M., & Daiss, J. L. (2015) · Clinical Orthopaedics and Related Research · doi:10.1007/s11999-015-4354-2 · Cited by 60
Identification of Key Determinants of Staphylococcus aureus Vaginal Colonization
Deng, L., Schilcher, K., Burcham, L. R., Kwiecinski, J. M., Johsnon, P. M., Head, S. R., Heinrichs, D. E., Horswill, A. R., & Doran, K. S. (2019) · mBio · doi:10.1128/mbio.02321-19 · Cited by 62
Iron-Regulated Surface Determinant (Isd) Proteins of Staphylococcus lugdunensis
Zapotoczna, M., Heilbronner, S., Speziale, P., & Foster, T. J. (2012) · Journal of Bacteriology · doi:10.1128/jb.01195-12 · Cited by 56
A randomized phase I study of the safety and immunogenicity of three ascending dose levels of a 3-antigen Staphylococcus aureus vaccine (SA3Ag) in healthy adults
Nissen, M. D., Marshall, H. S., Richmond, P., Shakib, S., Jiang, Q. L., Cooper, D., Rill, D., Baber, J., Eiden, J. J., Gruber, W. C., et al. (2015) · Vaccine · doi:10.1016/j.vaccine.2015.02.024 · Cited by 59
A human monoclonal antibody targeting the conserved staphylococcal antigen IsaA protects mice against Staphylococcus aureus bacteremia
van den Berg, S., Bonarius, H. P. J., van Kessel, K. P. M., Elsinga, G. S., Kooi, N. M., Westra, H., Bosma, T., van der Kooi‐Pol, M. M., Koedijk, D. G. A. M., Groen, H., et al. (2014) · International Journal of Medical Microbiology · doi:10.1016/j.ijmm.2014.11.002 · Cited by 59
Localization of Staphylococcus aureus in tissue from the nasal vestibule in healthy carriers
Hanssen, A.-M., Kindlund, B., Stenklev, N. C., Furberg, A., Fismen, S., Olsen, R. S., Johannessen, M., & Ericson, J. U. (2017) · BMC Microbiology · doi:10.1186/s12866-017-0997-3 · Cited by 59
Structural Basis for Hemoglobin Capture by Staphylococcus aureus Cell-surface Protein, IsdH
Kumar, K. K., Jacques, D. A., Pishchany, G., Caradoc-Davies, T. T., Spirig, T., Malmirchegini, G. R., Langley, D. B., Dickson, C. F., Mackay, J. P., Clubb, R., et al. (2011) · Journal of Biological Chemistry · doi:10.1074/jbc.m111.287300 · Cited by 58
Iron-Coordinating Tyrosine Is a Key Determinant of NEAT Domain Heme Transfer
Grigg, J. C., Mao, C. X., & Murphy, M. E. P. (2011) · Journal of Molecular Biology · doi:10.1016/j.jmb.2011.08.047 · Cited by 57
Functional Antibodies Targeting IsaA of Staphylococcus aureus Augment Host Immune Response and Open New Perspectives for Antibacterial Therapy
Lorenz, U., Lorenz, B., Schmitter, T., Streker, K., Erck, C., Wehland, J., Nickel, J., Zimmermann, B., & Ohlsen, K. (2010) · Antimicrobial Agents and Chemotherapy · doi:10.1128/aac.01144-10 · Cited by 59
Targeted Immunotherapy for Staphylococcal Infections
Otto, M. J. (2008) · BioDrugs · doi:10.2165/00063030-200822010-00003 · Cited by 55
Staphylococcal Protein A Contributes to Persistent Colonization of Mice with Staphylococcus aureus
Sun, Y., Emolo, C., Holtfreter, S., Wiles, S., Kreiswirth, B. N., Missiakas, D. M., & Schneewind, O. (2018) · Journal of Bacteriology · doi:10.1128/jb.00735-17 · Cited by 55
Does Staphylococcus Aureus Nasal Colonization Involve Biofilm Formation?
Krismer, B., & Peschel, A. (2011) · Future Microbiology · doi:10.2217/fmb.11.37 · Cited by 54
Strategies for and advances in the development ofStaphylococcus aureusprophylactic vaccines
Broughan, J. H., Anderson, R., & Anderson, A. S. (2011) · Expert Review of Vaccines · doi:10.1586/erv.11.54 · Cited by 52
Comparison of carboxylated and Penta-His microspheres for semi-quantitative measurement of antibody responses to His-tagged proteins
Verkaik, N. J., Brouwer, E., Hooijkaas, H., van Belkum, A., & van Wamel, W. J. B. (2008) · Journal of Immunological Methods · doi:10.1016/j.jim.2008.02.022 · Cited by 52
Protection from the acquisition of Staphylococcus aureus nasal carriage by cross-reactive antibody to a pneumococcal dehydrogenase
Lijek, R. S., Luque, S. L., Liu, Q., Parker, D., Bae, T., & Weiser, J. N. (2012) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1208075109 · Cited by 54
Innate Immune Memory Contributes to Host Defense against Recurrent Skin and Skin Structure Infections Caused by Methicillin-Resistant Staphylococcus aureus
Chan, L. C., Chaili, S., Filler, S. G., Miller, L. S., Solis, N. V., Wang, H., Johnson, C. W., Lee, H. K., Diaz, L. F., & Yeaman, M. R. (2016) · Infection and Immunity · doi:10.1128/iai.00876-16 · Cited by 50
Immunotherapeutic Approaches against Staphylococcus Aureus
Verkaik, N. J., van Wamel, W. J. B., & van Belkum, A. (2011) · Immunotherapy · doi:10.2217/imt.11.84 · Cited by 49
Staphylococcus aureus seroproteomes discriminate ruminant isolates causing mild or severe mastitis
Maréchal, C. L., Jardin, J., Jan, G., Even, S., Pulido, C., Guibert, J.-M., Hernández, D., François, P., Schrenzel, J., Demon, D., et al. (2011) · Veterinary Research · doi:10.1186/1297-9716-42-35 · Cited by 47
Selection and Characterization of Murine Monoclonal Antibodies toStaphylococcus aureusIron-Regulated Surface Determinant B with Functional Activity In Vitro and In Vivo
Brown, M. J., Kowalski, R., Zorman, J. K., Wang, X.-M., Towne, V., Zhao, Q., Secore, S., Finnefrock, A. C., Ebert, T., Pancari, G., et al. (2009) · Clinical and Vaccine Immunology · doi:10.1128/cvi.00085-09 · Cited by 45
The iron-regulated staphylococcal lipoproteins
Sheldon, J. R., & Heinrichs, D. E. (2012) · Frontiers in Cellular and Infection Microbiology · doi:10.3389/fcimb.2012.00041 · Cited by 46

Authors: Clarke, S. R., Brummell, K. J., Horsburgh, M. J., McDowell, P. W., Mohamad, S. A. S., Stapleton, M. R., Acevedo, J., Read, R. C., Day, N. P. J., Peacock, S. J., Mond, J. J., Kokai‐Kun, J. F., & Foster, S. J.
Affiliations: University of Sheffield (GB)
Mahidol University (TH)
ORCID: Clarke, Simon R.
Horsburgh, Malcolm J.
Mohamad, Sharifah A. Syed
Read, Robert C.
Peacock, Sharon J.
Kokai‐Kun, John F.
Foster, Simon J.
Venue: The Journal of Infectious Diseases
Publisher: Oxford University Press (OUP)
Published: 2006-04-15
Volume: 193
Issue: 8
Pages: 1098-1108
ISSN: 0022-1899 (ISSN-L)
1537-6613
DOI: 10.1086/501471
OpenAlex: W2103675658
Cited by: 208
References: 49
Citations by year: 2026: 2 · 2025: 4 · 2024: 7 · 2023: 4 · 2022: 4 · 2021: 1 · 2020: 6 · 2019: 9 · 2018: 10 · 2017: 8 · 2016: 12 · 2015: 19 · 2014: 8 · 2013: 12 · 2012: 16
FWCI: 9.50
Type: journal article
Language: en
Open access: closed
Locations: The Journal of Infectious Diseases (publishedVersion)
PubMed (publishedVersion)
ePrints Soton (University of Southampton) (submittedVersion)
Funders: Vanderbilt University
Wellcome Trust
Topics: Health Sciences › Medicine › Infectious Diseases › Antimicrobial Resistance in Staphylococcus
Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › vaccines and immunoinformatics approaches
Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Biochemical and Structural Characterization
Keywords: Staphylococcus aureus, nasal carriage, bacterial antigens, IgG, ISDA, IsdH, vaccine development, bacterial adhesion, cotton rat model, antibody titers
MeSH terms: Animals, Antibodies, Bacterial, Antigens, Bacterial, Bacterial Vaccines, Carrier State, Cells, Cultured, Epithelial Cells, Female, Humans, Immunoglobulin G, Nasal Cavity, Receptors, Cell Surface, Recombinant Proteins, Staphylococcal Infections, Staphylococcus aureus, Sigmodontinae, DNA Primers, Cation Transport Proteins

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review

Identification of In Vivo–Expressed Antigens of Staphylococcus aureus and Their Use in Vaccinations for Protection against Nasal Carriage

Abstract

Overview

Integrity signals

Verification

Claims the paper makes

Claims other papers make about this one

Self-check

Citations

Cites

Cited by

Related

Metadata

Record

About these checks