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Cited by 438Antifungal resistance and susceptibilityFungal Infections and StudiesOcular Infections and Treatments

The DOI matches its Crossref record; 26 of the 26 references it cites were found in a registry or an index.

Excess Mortality, Hospital Stay, and Cost Due to Candidemia: A Case-Control Study Using Data From Population-Based Candidemia Surveillance

Morgan, Juliette, Meltzer, Martin I., Plikaytis, Brian D., Sofair, Andre N., Huie-White, Sharon, Wilcox, Steven, Harrison, Lee H., Seaberg, Eric C., Hajjeh, Rana A., Teutsch, Steven M.·2005·Infection Control & Hospital Epidemiology
DOI 10.1086/502581
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Abstract

Objective: To determine the mortality, hospital stay, and total hospital charges and cost of hospitalization attributable to candidemia by comparing patients with candidemia with control-patients who have otherwise similar illnesses. Prior studies lack broad patient and hospital representation or cost-related information that accurately reflects current medical practices. Design: Our case-control study included case-patients with candidemia and their cost-related data, ascertained from laboratory-based candidemia surveillance conducted among all residents of Connecticut and Baltimore and Baltimore County, Maryland, during 1998 to 2000. Control-patients were matched on age, hospital type, admission year, discharge diagnoses, and duration of hospitalization prior to candidemia onset. Results: We identified 214 and 529 sets of matched case-patients and control-patients from the two locations, respectively. Mortality attributable to candidemia ranged between 19% and 24%. On multivariable analysis, candidemia was associated with mortality (OR, 5.3 for Connecticut and 8.5 for Baltimore and Baltimore County;P< .05), whereas receiving adequate treatment was protective (OR, 0.5 and 0.4 for the two locations, respectively;P< .05). Candidemia itself did not increase the total hospital charges and cost of hospitalization; when treatment status was accounted for, having received adequate treatment for candidemia significantly increased the total hospital charges and cost of hospitalization ($6,000 to $29,000 and $3,000 to $22,000, respectively) and the length of stay (3 to 13 days). Conclusion: Our findings underscore the burden of candidemia, particularly regarding the risk of death, length of hospitalization, and cost associated with treatment (Infect Control Hosp Epidemiol 2005;26:540-547).

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Crossref · 10.1086/502581

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Research works printed but not linked: 5

  1. Haddix, 2003, Prevention Effectiveness, 53
  2. Consumer Price Index
  3. ChimeData Program
  4. Health Services Cost Review
  5. 10.1001/archinte.1995.00430110089009 · DOI · Paper page

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Metadata

Authors
Morgan, J., Meltzer, M. I., Plikaytis, B. D., Sofair, A. N., Huie-White, S., Wilcox, S., Harrison, L. H., Seaberg, E. C., Hajjeh, R. A., & Teutsch, S. M.
Affiliations
  • Centers for Disease Control and Prevention (US)
  • Johns Hopkins University (US)
  • Merck & Co., Inc., Rahway, NJ, USA (United States) (US)
Corresponding author
Morgan, Juliette
ORCID
Venue
Infection Control & Hospital Epidemiology
Publisher
Cambridge University Press (CUP)
Published
2005-06
Volume
26
Issue
6
Pages
540-547
ISSN
  • 0899-823X (ISSN-L)
  • 1559-6834
DOI
10.1086/502581
OpenAlex
W2138648278
Semantic Scholar
fbb5a839e0dc3b43795b4bba8e920640a069b23b
Cited by
437
References
26
Citations by year
2026: 9 · 2025: 13 · 2024: 16 · 2023: 15 · 2022: 18 · 2021: 15 · 2020: 21 · 2019: 24 · 2018: 10 · 2017: 19 · 2016: 24 · 2015: 27 · 2014: 18 · 2013: 26 · 2012: 36
FWCI
11.94
Type
journal article
Language
en
Open access
closed
Licence
www.cambridge.org/core/terms (unspecified, 4038 d)
Locations
  • Infection Control and Hospital Epidemiology (publishedVersion)
  • PubMed (publishedVersion)
Topics
  • Health Sciences › Medicine › Infectious Diseases › Antifungal resistance and susceptibility
  • Health Sciences › Medicine › Infectious Diseases › Fungal Infections and Studies
  • Health Sciences › Medicine › Ophthalmology › Ocular Infections and Treatments
Keywords
candidemia, excess mortality, length of hospital stay, hospital costs, fungemia, Connecticut, Baltimore
MeSH terms
Adolescent, Adult, Candidiasis, Child, Child, Preschool, Connecticut, Cross Infection, Female, Humans, Infant, Length of Stay, Male, Middle Aged, Population Surveillance, Baltimore, Multivariate Analysis, Linear Models, Case-Control Studies, Fungemia, Hospital Mortality, Cost of Illness, Age Distribution, Hospital Costs, Hospital Charges

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