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Acute Respiratory Distress Syndrome and Pneumonia: A Comprehensive Review of Clinical Data
Open accessAbstract
Acute respiratory distress syndrome (ARDS) and pneumonia are closely correlated in the critically ill patient. Whereas ARDS is often complicated by nosocomial pneumonia, pulmonary infection is also the most frequent single cause of ARDS. The prevalence of pneumonia during the course of ARDS seems to be particularly high, but whether persons with ARDS are more susceptible to pneumonia or simply have more risk factors remains unknown because of methodological limitations. Recent research suggests that host factors have a major bearing on the development of ARDS. To date, sepsis seems to be the principal link between pneumonia and ARDS. However, prospective observational data on this supposed sequence are not available. The individual role of specific pathogens for the development of ARDS is difficult to assess, because prospective studies are missing. Respiratory viruses have received particular attention, but this review suggests that infections with coronavirus and avian influenza virus (H5N1) are associated with a high incidence of ARDS.
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“roughly half of patients with established ARDS develop pneumonia during intensive care.”
From The microbiome and critical illness (2016) · cites this paper as [114]
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“Pneumonia is the most common cause of ARDS”
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Narasaraju, T., Yang, E., Samy, R. P., Ng, H. H., Poh, W. P., Liew, A.-A., Phoon, M. C., van Rooijen, N., & Chow, V. T. K. (2011) · American Journal Of Pathology · doi:10.1016/j.ajpath.2011.03.013 · Cited by 918
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Metadata
- Authors
- Bauer, T. T., Ewig, S., Rodloff, A. C., & Muller, E. E.
- Affiliations
- Helios Klinikum Emil von Behring (DE)
- Universitätsklinikum Knappschaftskrankenhaus Bochum (DE)
- Leipzig University (DE)
- Corresponding author
- Bauer, T. T.
- ORCID
- Bauer, T. T.
- Venue
- Clinical Infectious Diseases
- Publisher
- Oxford University Press (OUP)
- Published
- 2006-09-15
- Volume
- 43
- Issue
- 6
- Pages
- 748-756
- ISSN
- 1058-4838 (ISSN-L)
- 1537-6591
- PMC
- PMC7107989
- OpenAlex
- W2156551852
- Cited by
- 151
- References
- 81
- Citations by year
- 2026: 3 · 2025: 11 · 2024: 7 · 2023: 6 · 2022: 10 · 2021: 19 · 2020: 12 · 2019: 8 · 2018: 10 · 2017: 12 · 2016: 5 · 2015: 2 · 2014: 10 · 2013: 3 · 2012: 6
- FWCI
- 0.61
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Locations
- Clinical Infectious Diseases (publishedVersion)
- Europe PMC (PubMed Central) (publishedVersion)
- PubMed Central (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Pulmonary and Respiratory Medicine › Respiratory Support and Mechanisms
- Health Sciences › Medicine › Critical Care and Intensive Care Medicine › Nosocomial Infections in ICU
- Health Sciences › Medicine › Critical Care and Intensive Care Medicine › Sepsis Diagnosis and Treatment
- Keywords
- acute respiratory distress syndrome, pneumonia, nosocomial pneumonia, sepsis, host factors, respiratory viruses, coronavirus, H5N1 avian influenza, critically ill patients
- MeSH terms
- Animals, Bacteria, Disease Susceptibility, Humans, Parasites, Pneumonia, Respiratory Distress Syndrome, Respiratory Tract Infections, Risk Factors, Coronavirus, Sepsis, Influenza A Virus, H5N1 Subtype
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