The DOI matches its Crossref record; 22 of the 22 references it cites were found in a registry or an index.
HLA and Mate Choice in Humans
Open accessAbstract
Evidence from studies in rodents suggests that mate selection is influenced by major-histocompatibility-complex haplotypes, with preferences for dissimilar partners. This study was initiated to determine whether avoidance of a mate with the same HLA haplotype as one's own might be occurring in the Hutterites, a North American reproductive isolate of European ancestry, notable for their large sibships, communal lifestyle, and limited number of five-locus HLA haplotypes (HLA-A, -B, -C, -DR, and -DQ). HLA haplotypes were known for 411 Hutterite couples. The number of couples expected to match for a haplotype was calculated in two ways: first, from population genotype frequencies, with account being taken of the nonrandom mating pattern with respect to colony lineages, and, second, from computer simulations using conservative founder assumptions and the exact genealogy of the 411 couples. We observed fewer matches for HLA haplotypes between spouses than expected (first method, P = .005; second method, P = .020-.067). Among couples who did match for a haplotype, the matched haplotype was inherited from the mother in 29 cases and from the father in 50 cases (P = .018). These results are consistent with the conclusion that Hutterite mate choice is influenced by HLA haplotypes, with an avoidance of spouses with haplotypes that are the same as one's own.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
The Genetics of Human Populations.
Bulmer, M. G., Cavalli-Sforza, L. L., & Bodmer, W. F. (1972) · Journal of the Royal Statistical Society. Series A (General) · doi:10.2307/2344702 · Cited by 1,658
The Genetics of Human Populations
J., A., Cavali-Sforza, L. L., & Bodmer, W. F. (1972) · Population (French Edition) · doi:10.2307/1529365 · Cited by 1,207
Chemical Signals in Vertebrates
(1977) · Springer eBooks · doi:10.1007/978-1-4684-2364-8 · Cited by 1,140
Human Genetics. Problems and Approaches.
(1980) · Annals of Internal Medicine · doi:10.7326/0003-4819-93-1-163_3 · Cited by 991
MHC-dependent mate preferences in humans
(1995) · Proceedings of the Royal Society of London. Series B: Biological Sciences · doi:10.1098/rspb.1995.0087 · Cited by 953
Control of mating preferences in mice by genes in the major histocompatibility complex.
Yamazaki, K., Boyse, E. A., Miké, V, Thaler, H. T., Mathieson, B. J., Abbott, J., Boyse, J., Zayas, Z. A., & Thomas, L. (1976) · The Journal of experimental medicine · doi:10.1084/jem.144.5.1324 · Cited by 687
Mating patterns in seminatural populations of mice influenced by MHC genotype
Potts, W. K., Manning, C. J., & Wakeland, E. K. (1991) · Nature · doi:10.1038/352619a0 · Cited by 638
Mammalian Dispersal Patterns: The Effects of Social Structure on Population Genetics
Simberloff, D., Chepko-Sade, B. D., & Halpin, Z. T. (1989) · The Condor · doi:10.2307/1368098 · Cited by 276
Yamazaki, K., Yamaguchi, M., Baranoski, L., Bard, J., Boyse, E. A., & Thomas, L. (1979) · The Journal of experimental medicine · doi:10.1084/jem.150.4.755 · Cited by 244
Familial Imprinting Determines H-2 Selective Mating Preferences
Yamazaki, K., Beauchamp, G. K., Kupniewski, D., Bard, J., Thomas, L., & Boyse, E. A. (1988) · Science · doi:10.1126/science.3375818 · Cited by 221
Cited by
Disgust: evolved function and structure
Tybur, J. M., Lieberman, D., Kurzban, R., & DeScioli, P. (2013) · Psychological Review · doi:10.1037/a0030778 · Cited by 810
The architecture of human kin detection
Lieberman, D., Tooby, J., & Cosmides, L. (2007) · Nature · doi:10.1038/nature05510 · Cited by 748
An initial evaluation of the functions of human olfaction
Stevenson, R. J. (2010) · Chemical Senses · doi:10.1093/chemse/bjp083 · Cited by 689
The Scent of Genetic Compatibility: Sexual Selection and the Major Histocompatibility Complex
Penn, D. J. (2002) · Ethology · doi:10.1046/j.1439-0310.2002.00768.x · Cited by 503
Wedekind, C., & Füri, S. (1997) · Proceedings of the Royal Society of London. Series B: Biological Sciences · doi:10.1098/rspb.1997.0204 · Cited by 494
Metadata
- Authors
- Ober, C., Weitkamp, L. R., Cox, N., Dytch, H., Kostyu, D., & Elias, S.
- Venue
- The American Journal of Human Genetics
- Publisher
- Elsevier BV
- Published
- 1997-09
- Volume
- 61
- Issue
- 3
- Pages
- 497-504
- ISSN
- 0002-9297 (ISSN-L)
- OpenAlex
- W2123468478
- Cited by
- 373
- References
- 22
- FWCI
- 9.31
- Type
- journal article
- Language
- en
- Open access
- hybrid
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
How to cite
Cite CoChat for the checks on this page, and the paper for its own findings.
- This page
- CoChat. (2026). Citation check: HLA and Mate Choice in Humans. https://app.cochat.ai/papers/10.1086/515511
- The paper
- Ober, C., Weitkamp, L. R., Cox, N., Dytch, H., Kostyu, D., & Elias, S. (1997). HLA and Mate Choice in Humans. The American Journal of Human Genetics. https://doi.org/10.1086/515511
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
