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Cited by 268

The DOI matches its Crossref record; 11 of the 11 references it cites were found in a registry or an index.

Skin and Soft‐Tissue Infections Caused by Community‐Acquired Methicillin‐Resistant Staphylococcus aureus

Stryjewski, Martin E., Chambers, Henry F.·2008·Clinical Infectious Diseases

Abstract

Community-acquired methicillin-resistant Staphylococcus aureus (MRSA) infection has become epidemic. Skin and soft-tissue infections (SSTIs) are the most frequent forms of the disease. Obtainment of culture specimens is important for documentation of the presence of MRSA and for susceptibility testing to guide therapy. Purulent lesions should be drained whenever possible. In areas where community-acquired MRSA isolates are prevalent, uncomplicated SSTI in healthy individuals may be treated empirically with clindamycin, trimethoprim-sulfamethoxazole, or long-acting tetracyclines, although specific data supporting the efficacy of these treatments are lacking. In healthy patients with small purulent lesions, drainage alone may be sufficient. In patients with complicated SSTI requiring hospitalization or intravenous therapy, vancomycin is the drug of choice because of the low cost, efficacy, and safety. Linezolid, daptomycin, and tigecycline are also effective, although published studies on the last 2 agents for the treatment of SSTI due to MRSA are more limited. Dalbavancin, telavancin, and ceftobiprole are investigational agents that may expand our therapeutic options for the treatment of SSTI caused by MRSA.

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Metadata

Authors
Stryjewski, M. E., & Chambers, H. F.
Venue
Clinical Infectious Diseases
Published
2008-06
Volume
46
Issue
S5
Pages
S368-S377
ISSN
  • 1058-4838 (ISSN-L)
  • 1537-6591
OpenAlex
W2141620414
Cited by
268
References
11
FWCI
17.85
Type
journal article
Language
en
Open access
closed

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This page
CoChat. (2026). Citation check: Skin and Soft‐Tissue Infections Caused by Community‐Acquired Methicillin‐Resistant Staphylococcus aureus. https://app.cochat.ai/papers/10.1086/533593
The paper
Stryjewski, M. E., & Chambers, H. F. (2008). Skin and Soft‐Tissue Infections Caused by Community‐Acquired Methicillin‐Resistant Staphylococcus aureus. Clinical Infectious Diseases. https://doi.org/10.1086/533593

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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.