Cited by 207Nanoparticle-Based Drug DeliveryAdvanced Drug Delivery SystemsSurfactants and Colloidal Systems

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Polymeric worm micelles as nano-carriers for drug delivery

Kim, Younghoon, Dalhaimer, Paul, Christian, David A, Discher, Dennis E·2005·Nanotechnology

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Abstract

Nanoscale carriers of active compounds, especially drugs, need not be spherical in shape. Worm micelles as blends of degradable polylactic acid (PLA) and inert block copolymer amphiphiles were prepared for controlled release and initial study of carrier transport through nano-porous media. The loading capacity of a typical hydrophobic drug, Triamterene, and the release of hydrophobic dyes were evaluated together with morphological changes of the micelles. Degradation of PLA by hydrolysis led to the self-shortening of worms and a clear transition towards spherical micelles, correlating with the release of hydrophobic dyes. Perhaps equally important for application is the flexibility of worm micelles, which we show allows them to penetrate nanoporous gels where 100 nm sized vesicles cannot enter. Such gels have served as tissue models, and so the results here collectively suggest a new class of hydrophobic drug nano-carriers that are capable of tissue permeation as well as controlled release.

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Deamer, D. W., & Bramhall, J. S. (1986) · Chemistry and Physics of Lipids · doi:10.1016/0009-3084(86)90069-1 · Cited by 332
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Show all 24 references

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Serwer P, 1988, Electrophoresis’ 88, 216

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Authors: Kim, Y., Dalhaimer, P., Christian, D. A., & Discher, D. E.
Affiliations: University of Pennsylvania (US)
Corresponding author: Dalhaimer, Paul
ORCID: Kim, Younghoon
Dalhaimer, Paul
Christian, David A
Discher, Dennis E
Venue: Nanotechnology
Publisher: IOP Publishing
Published: 2005-05-18
Volume: 16
Issue: 7
Pages: S484-S491
ISSN: 0957-4484 (ISSN-L)
1361-6528
DOI: 10.1088/0957-4484/16/7/024
OpenAlex: W2127597183
Cited by: 207
References: 24
Citations by year: 2026: 1 · 2025: 4 · 2024: 6 · 2023: 5 · 2022: 4 · 2021: 7 · 2020: 7 · 2019: 8 · 2018: 9 · 2017: 8 · 2016: 10 · 2015: 9 · 2014: 15 · 2013: 14 · 2012: 12
FWCI: 6.97
Type: journal article
Language: en
Open access: closed
Locations: Nanotechnology (publishedVersion)
PubMed (publishedVersion)
Funders: National Institute of Biomedical Imaging and Bioengineering
Topics: Physical Sciences › Materials Science › Biomaterials › Nanoparticle-Based Drug Delivery
Life Sciences › Pharmacology, Toxicology and Pharmaceutics › Pharmaceutical Science › Advanced Drug Delivery Systems
Physical Sciences › Chemistry › Physical and Theoretical Chemistry › Surfactants and Colloidal Systems
Keywords: wormlike micelles, polymeric micelles, drug delivery, polylactic acid, amphiphilic block copolymers, controlled release, triamterene, hydrophobic drug loading, hydrolytic degradation, micelle morphology

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Polymeric worm micelles as nano-carriers for drug delivery

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