The DOI matches its Crossref record; 41 of the 41 references it cites were found in a registry or an index.
Validation of a device to measure arterial pulse wave velocity by a photoplethysmographic method
Open accessAbstract
We aimed to validate a new method for measuring arterial pulsewave transit time and pulsewave velocity (a measure of arterial elasticity), based on the principle of photoplethysmography (PPG), and to compare transcutaneous values with those obtained by intra-arterial measurements. Three validation experiments are described. (a) PPG pulse wave delay times (defined as the time interval between the ECG R wave and the foot of the arterial pulse wave measured at the wrist or ankle) were compared to values obtained simultaneously from an established methodology (Doppler ultrasound). (b) Aortic pulsewave delay times in 17 subjects obtained non-invasively by the PPG method were compared with those obtained from the intra-arterial pressure wave. (c) Repeatability measurements of PWV on the same subjects were carried out over two timescales (minutes and hours) in the arm, the leg and the trunk. The Doppler and PPG delay times correlated well, as did intra-arterial and transcutaneous values. Repeatability at short timescales was good (coefficients of variation (CV) < 6% for all measurement sites) and, at the longer timescale, was satisfactory (CVs in the aorta, the arm and leg were 6.3, 13.1 and 16.0, respectively). The PWV values agreed well with others in the literature. We conclude that the PPG technique provides a complement to existing methods for the non-invasive measurement of arterial compliance. Its simplicity and ease of use make it suitable for large-scale epidemiological studies.
Overview
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
In the citing paper
“advances in sensor technology for arterial pulse waveform and speed detection have paved the way for the potential development of devices for cuffless measurement of BP, in the perspective of continuous, beat-by-beat monitoring [103–106]”
In the citing paper
“some of such devices have been validated according to ad hoc draft protocols whereas others according to standard protocols [107,108], thus resulting in heterogenous and difficult to interpret evidence on their accuracy”
Citations
Cites
STATISTICAL METHODS FOR ASSESSING AGREEMENT BETWEEN TWO METHODS OF CLINICAL MEASUREMENT
Martin Bland, J., & Altman, D. (1986) · The Lancet · doi:10.1016/s0140-6736(86)90837-8 · Cited by 47,965
Avolio, A. P., Chen, S. G., Wang, R. P., Zhang, C. L., Li, M., & OʼRourke, M. F. (1983) · Circulation · doi:10.1161/01.cir.68.1.50 · Cited by 965
The Fluid Mechanics of Large Blood Vessels
Pedley, T. J., & Fung, Y. C. (1980) · Journal of Biomechanical Engineering · doi:10.1115/1.3138235 · Cited by 916
KARAMANOGLU, M., O'ROURKE, M. F., AVOLIO, A. P., & KELLY, R. P. (1993) · European Heart Journal · doi:10.1093/eurheartj/14.2.160 · Cited by 873
Avolio, A. P., Deng, F. Q., Li, W. Q., Luo, Y., Huang, Z., Xing, L. F., & O’Rourke, M. F. (1985) · Circulation · doi:10.1161/01.cir.71.2.202 · Cited by 838
Arterial stiffness, systolic blood pressure, and logical treatment of arterial hypertension.
O'Rourke, M. (1990) · Hypertension · doi:10.1161/01.hyp.15.4.339 · Cited by 621
Latham, R. D., Westerhof, N., Sipkema, P., Rubal, B., Reuderink, P., & Murgo, J. (1985) · Circulation · doi:10.1161/01.cir.72.6.1257 · Cited by 499
Growth in utero, adult blood pressure, and arterial compliance.
Martyn, C. N., Barker, D. J. P., Jespersen, S., Greenwald, S. E., Osmond, C., & Berry, C. L. (1995) · Heart · doi:10.1136/hrt.73.2.116 · Cited by 362
Self-citationDetermination of pulse wave velocities with computerized algorithms
Chiu, Y. C., Arand, P. W., Shroff, S. G., Feldman, T. E., & Carroll, J. D. (1991) · American Heart Journal · doi:10.1016/0002-8703(91)90153-9 · Cited by 313
Tardy, Y., Meister, J. ‐., Perret, F., Brunner, H. R., & Arditi, M. (1991) · Clinical Physics and Physiological Measurement · doi:10.1088/0143-0815/12/1/003 · Cited by 268
Pulse Pressure, Arterial Stiffness, and Drug Treatment of Hypertension
Bortel, L. M. V., Struijker-Boudier, H. A. J., & Safar, M. E. (2001) · Hypertension · doi:10.1161/hy1001.095773 · Cited by 240
Laurent, S., Girerd, X. J., Mourad, J., Lacolley, P. J., Beck, L., Boutouyrie, P., Mignot, J. P., & Safar, M. E. (1994) · Arteriosclerosis and Thrombosis A Journal of Vascular Biology · doi:10.1161/01.atv.14.7.1223 · Cited by 236
Farrar, D. J., Bond, M. G., Riley, W. A., & Sawyer, J. K. (1991) · Circulation · doi:10.1161/01.cir.83.5.1754 · Cited by 214
A manual of psychophysiological methods
Venables, P. H., & de Miguel, I. M. (1967) · Medical Entomology and Zoology · Cited by 201
Opposing effects of ageing on distal and proximal large arteries in hypertensives
Boutouyrie, P., Laurent, S., Bénétos, A., Girerd, X. J., Hoeks, A. P. G., & Safar, M. E. (1992) · Journal of Hypertension · doi:10.1097/00004872-199208001-00023 · Cited by 199
DOMANSKI, M. J., Norman, J. E., WOLZ, M. M., Mitchell, G. F., & Pfeffer, M. A. (2001) · Hypertension · doi:10.1161/hy1001.092966 · Cited by 193
In vivo arterial compliance in man
Laogun, A. A., & Gosling, R. G. (1982) · Clinical Physics and Physiological Measurement · doi:10.1088/0143-0815/3/3/004 · Cited by 188
Mohiaddin, R. H., Firmin, D. N., & Longmore, D. B. (1993) · Journal of Applied Physiology · doi:10.1152/jappl.1993.74.1.492 · Cited by 184
A phase-locked echo tracking system for recording arterial diameter changes in vivo.
Hokanson, D. E., Mozersky, D. J., Sumner, D. S., & Strandness, D. E. (1972) · Journal of Applied Physiology · doi:10.1152/jappl.1972.32.5.728 · Cited by 152
Aortic and large artery stiffness: Current methodology and clinical correlations
Hickler, R. B. (1990) · Clinical Cardiology · doi:10.1002/clc.4960130504 · Cited by 120
Adams, J., Brooks, M., Redpath, T. W., Smith, F. W., Dean, J., Gray, J. A., Walton, S., & Trent, R. J. (1995) · Heart · doi:10.1136/hrt.73.3.265 · Cited by 116
Pulse wave velocity in healthy subjects and in patients with various disease states
ELIAKIM, M., Sapoznikov, D., & Weinman, J. (1971) · American Heart Journal · doi:10.1016/0002-8703(71)90229-8 · Cited by 107
Relationship between pulse-wave velocity and arterial elasticity
CALLAGHAN, F., Geddes, L. A., Babbs, C. F., & BOURLAND, J. D. (1986) · Medical & Biological Engineering & Computing · doi:10.1007/bf02441620 · Cited by 83
Wright, J. S., Cruickshank, J. K., Kontis, S., Doré, C. J., & Gosling, R. G. (1990) · Clinical Science · doi:10.1042/cs0780463 · Cited by 80
Effect of age on the in vitro reflection coefficient of the aortoiliac bifurcation in humans.
Greenwald, S. E., Carter, A., & Berry, C. L. (1990) · Circulation · doi:10.1161/01.cir.82.1.114 · Cited by 53
Self-citationMechanical properties of the ascending thoracic aorta of man
GOZNA, E. R., Marble, A. E., SHAW, A. J., & Winter, D. A. (1973) · Cardiovascular Research · doi:10.1093/cvr/7.2.261 · Cited by 42
Noninvasive measurements of aortic stiffness: methodological considerations.
Ed, L. (1999) · PubMed · Cited by 40
Techniques in the Determination of the Mechanical Properties and Constitutive Laws of Arterial Walls
Hayash, K., Stergiopulos, N., Meister, J.-J., Greenwald, S. E., & Rachev, A. (2000) · CRC Press eBooks · doi:10.1201/9781420049534.ch-06 · Cited by 33
Self-citationGreenwald, S. E., Newman, D. L., & Bowden, N. L. R. (1978) · Cardiovascular Research · doi:10.1093/cvr/12.7.407 · Cited by 28
Self-citationOn-line Doppler ultrasound measurement of aortic compliance and its repeatability in normal subjects
Kontis, S., & Gosling, R. G. (1989) · Clinical Physics and Physiological Measurement · doi:10.1088/0143-0815/10/2/002 · Cited by 27
Photoplethysmographic evaluation of the relationship between skin reflectance and skin blood volume
Higgins, J. L., & Fronek, A. S. (1986) · Journal of Biomedical Engineering · doi:10.1016/0141-5425(86)90047-6 · Cited by 19
Equipment for continuous measurements of pulse wave velocities
Weinman, J., & Sapoznikov, D. (1971) · Medical & Biological Engineering & Computing · doi:10.1007/bf02474741 · Cited by 18
Eze, C. U., Gupta, R., & Newman, D. L. (2000) · Physics in Medicine and Biology · doi:10.1088/0031-9155/45/9/312 · Cited by 18
Behaviour of Conduit Arteries in Hypertension
Me, S., & Laurent, S. (1993) · Clinical and Experimental Hypertension · doi:10.3109/10641969309037091 · Cited by 17
Noninvasive measurement of vascular compliance by a photoplesythmographic technique
Greenwald, S. E., Denyer, H. T., & Sobeh, M. S. (1997) · Proceedings of SPIE, the International Society for Optical Engineering/Proceedings of SPIE · doi:10.1117/12.275024 · Cited by 17
Self-citationArterial pulse wave velocity and left ventricular tension period in cardiac arrhythmias
Weinman, J., Sapoznikov, D., & ELIAKIM, M. (1971) · Cardiovascular Research · doi:10.1093/cvr/5.4.513 · Cited by 9
Sapoznikov, D., Weinman, J., & ELIAKIM, M. (1974) · PubMed · Cited by 8
ELIAKIM, M., Sapoznikov, D., & Weinman, J. (2008) · Cardiology · doi:10.1159/000169614 · Cited by 7
Measurement of Distensibility of Blood Vessels Using Cineangiograms
Sugahara, T., Yanagihara, Y., Uyama, C., Maeda, H., Takafuchi, M., & Azumi, T. (1989) · Investigative Radiology · doi:10.1097/00004424-198909000-00005 · Cited by 4
Reduction of Arterial Wall Mechanical Stress as a Goal for Antihypertensive Therapy
Laurent, S. (1994) · Journal of Cardiovascular Pharmacology · doi:10.1097/00005344-199423005-00008 · Cited by 4
Bt, P., Lehmann, E. D., Rp, K., Hayward, C., Avolio, A. P., & OʼRourke, M. F. (1996) · PubMed · Cited by 4
Research works printed but not linked: 4
- Greenwald S E, 1991, Med. Razgl., 30, 143
- Lehmann E D, 1999, Pathol. Biol. (Paris), 47, 716
- Plunkett B T, 1996, Zeit. Kardiol., 85, 136
- Sapoznikov D, 1974, Eur. J. Cardiol., 1, 447
Cited by
Sorted by citations
Photoplethysmography and its application in clinical physiological measurement
Allen, J. (2007) · Physiological Measurement · doi:10.1088/0967-3334/28/3/r01 · Cited by 3,967
Ageing of the conduit arteries
Greenwald, S. E. (2007) · The Journal of Pathology · doi:10.1002/path.2101 · Cited by 638
Self-citationPhotoplethysmography Revisited: From Contact to Noncontact, From Point to Imaging
Sun, Y., & Thakor, N. V. (2015) · IEEE Transactions on Biomedical Engineering · doi:10.1109/tbme.2015.2476337 · Cited by 589
Smart Vest: Wearable multi-parameter remote physiological monitoring system
Pandian, P. S., Mohanavelu, K., Safeer, K. P., Kotresh, T. M., Shakunthala, D. T., Gopal, P., & Padaki, V. C. (2007) · Medical Engineering & Physics · doi:10.1016/j.medengphy.2007.05.014 · Cited by 420
Pulse transit time measured from the ECG: an unreliable marker of beat-to-beat blood pressure
Payne, R. A., Symeonides, C. N., Webb, D. J., & Maxwell, S. R. J. (2006) · Journal of Applied Physiology · doi:10.1152/japplphysiol.00657.2005 · Cited by 418
Metadata
- Authors
- Loukogeorgakis, S., Dawson, R., Phillips, N., Martyn, C. N., & Greenwald, S. E.
- Affiliations
- St Bartholomew's Hospital (GB)
- Southampton General Hospital (GB)
- Venue
- Physiological Measurement
- Publisher
- IOP Publishing
- Published
- 2002-07-15
- Volume
- 23
- Issue
- 3
- Pages
- 581-596
- ISSN
- 0967-3334 (ISSN-L)
- OpenAlex
- W2006542548
- Cited by
- 164
- References
- 41
- Citations by year
- 2025: 5 · 2024: 3 · 2023: 6 · 2022: 4 · 2021: 12 · 2020: 6 · 2019: 3 · 2018: 7 · 2017: 8 · 2016: 4 · 2015: 9 · 2014: 2 · 2013: 6 · 2012: 11
- FWCI
- 6.34
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Locations
- Physiological Measurement (publishedVersion)
- PubMed (publishedVersion)
- ePrints Soton (University of Southampton) (submittedVersion)
- UCL Discovery (University College London) (submittedVersion)
- Topics
- Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Cardiovascular Health and Disease Prevention
- Physical Sciences › Engineering › Biomedical Engineering › Non-Invasive Vital Sign Monitoring
- Health Sciences › Medicine › Surgery › Hemodynamic Monitoring and Therapy
- Keywords
- pulse wave velocity, photoplethysmography, arterial compliance, pulse transit time, aortic pulse wave, Doppler ultrasound comparison, repeatability
- MeSH terms
- Ankle, Catheterization, Peripheral, Circadian Rhythm, Compliance, Femoral Artery, Heart Rate, Humans, Pulsatile Flow, Pulse, Wrist, Reproducibility of Results, Photoplethysmography, Ultrasonography, Doppler
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
