The DOI matches its Crossref record; 2 of the 2 references it cites were found in a registry or an index.
Breath acetone concentration decreases with blood glucose concentration in type I diabetes mellitus patients during hypoglycaemic clamps
Open accessAbstract
Conventional wisdom is that breath acetone may be markedly elevated in type 1 diabetes, but that this only occurs during poor blood glucose control and/or intercurrent illness. In contrast, little is known about breath acetone at more representative everyday blood glucose levels in diabetes. We used selected ion flow tube mass spectrometry to monitor the breath of eight patients with type 1 diabetes mellitus during 'insulin clamp' studies in which insulin and glucose were infused into patients to lower blood glucose levels in steps from normal values into the low glucose (hypoglycaemic) range. The concentration of acetone in breath and the blood sugar concentration of the patients were monitored at each blood glucose concentration. The blood glucose level at the start of the study was typically about 6 mM L(-1), whereas the breath acetone concentration at this blood glucose level was unexpectedly variable, ranging from 1 part-per-million to 21 ppm, in contrast to what was previously believed, i.e. that type 1 diabetes mellitus is characterized by high acetone levels. In all eight patients, the breath acetone declined linearly with blood glucose concentration.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
Turner, C., Španěl, P., & Smith, D. (2006) · Physiological Measurement · doi:10.1088/0967-3334/27/4/001 · Cited by 379
Self-citationAcetone metabolism during diabetic ketoacidosis
Owen, O. E., Trapp, V. E., Skutches, C. L., Mozzoli, M. A., Hoeldtke, R. D., Boden, G., & Reichard, G. A. (1982) · Diabetes · doi:10.2337/diab.31.3.242 · Cited by 190
Cited by
A review of the volatiles from the healthy human body
de Lacy Costello, B., Amann, A., Al-Kateb, H., Flynn, C., Filipiak, W., Khalid, T., Osborne, D., & Ratcliffe, N. M. (2014) · Journal of Breath Research · doi:10.1088/1752-7155/8/1/014001 · Cited by 1,042
Non-Invasive Blood Glucose Monitoring Technology: A Review
Tang, L., Chang, S. J., Chen, C.-J., & Liu, J.-T. (2020) · Sensors · doi:10.3390/s20236925 · Cited by 481
Li, G., Cheng, Z., Xiang, Q., Yan, L., Wang, X., & Xu, J. (2019) · Sensors and Actuators B: Chemical · doi:10.1016/j.snb.2018.09.117 · Cited by 422
Breath Analysis in Disease Diagnosis: Methodological Considerations and Applications
Lourenço, C., & Turner, C. (2014) · Metabolites · doi:10.3390/metabo4020465 · Cited by 314
Self-citationSensing Technologies for Detection of Acetone in Human Breath for Diabetes Diagnosis and Monitoring
Saasa, V., Malwela, T., Beukes, M., Mokgotho, M., Liu, C.-P., & Mwakikunga, B. (2018) · Diagnostics · doi:10.3390/diagnostics8010012 · Cited by 287
Metadata
- Authors
- Turner, C., Walton, C., Hoashi, S., & Evans, M.
- Venue
- Journal of Breath Research
- Publisher
- IOP Publishing
- Published
- 2009-12-01
- Volume
- 3
- Issue
- 4
- Pages
- 046004
- ISSN
- 1752-7155 (ISSN-L)
- 1752-7163
- OpenAlex
- W1991024809
- Cited by
- 183
- References
- 2
- FWCI
- 1.75
- Type
- journal article
- Language
- en
- Open access
- bronze
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
How to cite
Cite CoChat for the checks on this page, and the paper for its own findings.
- This page
- CoChat. (2026). Citation check: Breath acetone concentration decreases with blood glucose concentration in type I diabetes mellitus patients during hypoglycaemic clamps. https://app.cochat.ai/papers/10.1088/1752-7155/3/4/046004
- The paper
- Turner, C., Walton, C., Hoashi, S., & Evans, M. (2009). Breath acetone concentration decreases with blood glucose concentration in type I diabetes mellitus patients during hypoglycaemic clamps. Journal of Breath Research. https://doi.org/10.1088/1752-7155/3/4/046004
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
