Enhanced Expression of Transgenes from Adeno-Associated Virus Vectors with the Woodchuck Hepatitis Virus Posttranscriptional Regulatory Element: Implications for Gene Therapy

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AAV2 vector optimization for retinal ganglion cell-targeted delivery of therapeutic genes

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Modification of the adenoviral transfer vector enhances expression of the Hantavirus fusion protein GnS0.7 and induces a strong immune response in C57BL/6 mice

Li, P., Lan, Y., Wu, X., Bai, W., Li, K., Wang, H.-T., Hu, G., Zhang, L., Zhang, F., & Xu, Z. (2011) · Journal of Virological Methods · doi:10.1016/j.jviromet.2011.10.005 · Cited by 12

Improvement of lentiviral transfer vectors using cis-acting regulatory elements for increased gene expression

Real, G., Monteiro, F., Burger, C., & Alves, P. M. (2011) · Applied Microbiology and Biotechnology · doi:10.1007/s00253-011-3392-2 · Cited by 11

Construction of recombinant Marek's disease virus (MDV) lacking the meq oncogene and co-expressing AIV-H9N2 HA and NA genes under control of exogenous promoters

Zhang, Z., Chen, W., Ma, C., Zhao, P., Duan, L., Zhang, F., Sun, A., Li, Y., Su, H., Li, S., et al. (2014) · Journal of Biotechnology · doi:10.1016/j.jbiotec.2014.03.032 · Cited by 12

The assessment of adeno‐associated vectors as potential intrinsic treatments for brainstem axon regeneration

Williams, R. R., Pearse, D. D., Tresco, P. A., & Bunge, M. B. (2011) · The Journal of Gene Medicine · doi:10.1002/jgm.1628 · Cited by 11

Neural atrophy produced by AAV tau injections into hippocampus and anterior cortex of middle-aged mice

Tetlow, A. M., Jackman, B. M., Alhadidy, M. M., Muskus, P. C., Morgan, D., & Gordon, M. N. (2022) · Neurobiology of Aging · doi:10.1016/j.neurobiolaging.2022.06.014 · Cited by 10

Adeno-Associated Viral Gene Therapy for Retinal Disorders

Silva, S. R. D., McClements, M. E., Hankins, M. W., & MacLaren, R. E. (2015) · Neuromethods · doi:10.1007/978-1-4939-2306-9_9 · Cited by 10

E2F4-Based Gene Therapy Mitigates the Phenotype of the Alzheimer's Disease Mouse Model 5xFAD

López‐Sánchez, N., Garrido‐García, A., Ramón‐Landreau, M., Cano‐Daganzo, V., & Frade, J. M. (2021) · Neurotherapeutics · doi:10.1007/s13311-021-01151-1 · Cited by 11

Targeted Integration by Adeno-Associated Virus

Weitzman, M. D., Young, S. M., Cathomen, T., & Samulski, R. J. (2003) · Humana Press eBooks · doi:10.1385/1-59259-304-6:201 · Cited by 10

Diverse activities of viralcis-acting RNA regulatory elements revealed using multicolor, long-term, single-cell imaging

Pocock, G. M., Zimdars, L. L., Yuan, M., Eliceiri, K. W., Ahlquist, P., & Sherer, N. M. (2016) · Molecular Biology of the Cell · doi:10.1091/mbc.e16-08-0612 · Cited by 9

Retroviral Vector Technology for Gene Therapy: History, Current Landscape, and Future Prospects

Jaballah, S. A., Ali, L. M., Jehad, M. A., Akhlaq, S., Rizvi, T. A., & Mustafa, F. (2025) · Journal of Molecular Biology · doi:10.1016/j.jmb.2025.169473 · Cited by 10

5-HT1B autoreceptors differentially modulate the expression of conditioned fear in a circuit-specific manner

Liu, Y. K., Kelly, M. A., Sexton, T. J., & Neumaier, J. F. (2015) · Neuroscience · doi:10.1016/j.neuroscience.2015.04.032 · Cited by 10

A SIN lentiviral vector containing piga cdna allows long-term phenotypic correction of CD34+-derived cells from patients with paroxysmal nocturnal hemoglobinuria

Robert, D. B., Mahon, F., Richard, E., Étienne, G., de Verneuil, H., & Moreau‐Gaudry, F. (2003) · Molecular Therapy · doi:10.1016/s1525-0016(03)00011-x · Cited by 9

A Hepadnavirus Regulatory Element Enhances Expression of a Type 2 Bovine Viral Diarrhea Virus E2 Protein from a Bovine Herpesvirus 1 Vector

Wang, L., Menon, S. A., Bolin, S. R., & Bello, L. J. (2003) · Journal of Virology · doi:10.1128/jvi.77.16.8775-8782.2003 · Cited by 9

Recombinant Adeno-Associated Viral Vectors in the Nervous System

Bürger, C., Nash, K. R., & Mandel, R. J. (2005) · Human Gene Therapy · doi:10.1089/hum.2005.16.ft-64 · Cited by 9

Tracing goes viral: Viruses that introduce expression of fluorescent proteins in chemically-specific neurons

Luchicchi, A., Pattij, T., Viaña, J. N. M., de Kloet, S. F., & Marchant, N. J. (2020) · Journal of Neuroscience Methods · doi:10.1016/j.jneumeth.2020.109004 · Cited by 8

Intracellular efficacy of tumor‐targeting group I intron‐based trans‐splicing ribozyme

Kwon, B. S., Jeong, J. S., Won, Y.-S., Lee, C. H., Yoon, K., Jung, M. H., Kim, I., & Lee, S. (2011) · The Journal of Gene Medicine · doi:10.1002/jgm.1545 · Cited by 8

Exogenous Peptide and Protein Expression Levels Using Retroviral Vectors in Human Cells

Sandrock, T. M., Risley, B., Richards, B. T., Poritz, M. A., Austin, H. A., Yoo, S., Kim, M. K. H., Roth, B. L., Repetny, K., Hsu, F., et al. (2001) · Molecular Therapy · doi:10.1006/mthe.2001.0476 · Cited by 8

Construction and Characterization of Helper-Dependent Adenoviral Vectors for Sustained In Vivo Gene Therapy

Oka, K., & Chan, L. (2005) · Humana Press eBooks · doi:10.1385/1-59259-850-1:329 · Cited by 8

Systemic delivery of AAV-GCDH ameliorates HLD-induced phenotype in a glutaric aciduria type I mouse model

Mateu-Bosch, A., Segur‐Bailach, E., Muñoz‐Moreno, E., Barallobre, M. J., Arbonés, M. L., Gea‐Sorlí, S., Tort, F., Ribes, A., García‐Villoria, J., & Fillat, C. (2024) · Molecular Therapy — Methods & Clinical Development · doi:10.1016/j.omtm.2024.101276 · Cited by 7

GCaMP expression in retinal ganglion cells characterized using a low-cost fundus imaging system

Chang, Y.-C., Walston, S. T., Chow, R. H.-P., & Weiland, J. D. (2017) · Journal of Neural Engineering · doi:10.1088/1741-2552/aa7ded · Cited by 7

Gene Therapy for Retinal Disease: What Lies Ahead

MacLaren, R. E. (2015) · Ophthalmologica · doi:10.1159/000438872 · Cited by 7

Assessing adenoviral hammerhead ribozyme and small hairpin RNA cassettes in neurons: Inhibition of endogenous caspase‐3 activity and protection from apoptotic cell death

Bantounas, I., Glover, C. P. J., Kelly, S., Iseki, S., Phylactou, L. A., & Uney, J. B. (2005) · Journal of Neuroscience Research · doi:10.1002/jnr.20389 · Cited by 7

Enhancement of Green Fluorescent Protein Expression in Adeno-Associated Virus with the Woodchuck Hepatitis Virus Post-Transcriptional Regulatory Element

Loeb, J. E., Weitzman, M. D., & Hope, T. J. (2003) · Humana Press eBooks · doi:10.1385/1-59259-280-5:331 · Cited by 6

Woodchuck hepatitis virus post-transcriptional regulation element enhances transgene expression from adenovirus vectors

Xu, Z., Mizuguchi, H., Mayumi, T., & Hayakawa, T. (2003) · Biochimica et Biophysica Acta (BBA) - General Subjects · doi:10.1016/s0304-4165(03)00078-3 · Cited by 43

Woodchuck Hepatitis Virus Posttranscriptional Regulatory Element Enhances Expression of Transgenes Delivered by Retroviral Vectors

Zufferey, R., Donello, J. E., Trono, D., & Hope, T. J. (1999) · Journal of Virology · doi:10.1128/jvi.73.4.2886-2892.1999 · Cited by 1,030

Inclusion of the Woodchuck Hepatitis Virus Posttranscriptional Regulatory Element Enhances AAV2-Driven Transduction of Mouse and Human Retina

Patrício, M. I., Barnard, A. R., Orlans, H. O., McClements, M. E., & MacLaren, R. E. (2017) · Molecular Therapy — Nucleic Acids · doi:10.1016/j.omtn.2016.12.006 · Cited by 59

The hepatitis B virus posttranscriptional regulatory element is composed of two subelements

Zufferey, R., Donello, J. E., Trono, D., & Hope, T. J. (1996)