The DOI matches its Crossref record; 29 of the 29 references it cites were found in a registry or an index.
Pediatric Psychotropic Medication Compliance: A Literature Review and Research-Based Suggestions for Improving Treatment Compliance
Abstract
Without good compliance the best psychiatric treatment is ineffective. This article reviews what is known or can be inferred about compliance with psychiatric medications in the pediatric population. The review includes discussions of assessment techniques, risk and protective factors, the relevant research literature, and research-based practical techniques to improve compliance. A Medline search surveying the years from 1966 to August 2000 yielded only seven peer-reviewed papers reporting on compliance with pediatric psychopharmacology. All seven studies looked at stimulant compliance among children with attention deficit hyperactivity disorder. Reported levels of compliance range from 56% to 75%. These rates, although low, are likely to be overestimates of actual compliance. We review two related areas of research for which there are small but significant bodies of knowledge: pharmacological compliance studies among adult psychiatric populations and pediatric medical populations. This literature supports the idea that medication compliance is a significant obstacle to the effective treatment of patients. Because compliance rates are lower for children as compared to adults and psychiatric patients as compared to medical patients, we suspect that children with psychiatric illness may be at great risk for poor medication compliance. Fortunately, the research literature demonstrates several simple techniques that clinicians can use to improve medication compliance among their patients. The treatment alliance; education; and medication duration, dosing, palatability, and cost can all be tailored to improve medication compliance.
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In the citing paper
“estimated adherence rates in children with ADHD only range from 56% to 75%, 16 and more than 50% of patients with ADHD discontinue treatment regardless of its efficacy or symptom severity.17,18”
From Medication Adherence in the MTA: Saliva Methylphenidate Samples Versus Parent Report and Mediating Effect of Concomitant Behavioral Treatment (2009) · cites this paper as [16]
In the citing paper
“Despite our high reported adherence rates, our physiological adherence findings are consistent with studies 1, 16,18,29 that have linked poor adherence to adverse outcomes.”
From Medication Adherence in the MTA: Saliva Methylphenidate Samples Versus Parent Report and Mediating Effect of Concomitant Behavioral Treatment (2009) · cites this paper as [16]
In the citing paper
“However, unlike some previous studies, we found no associations between adherence and demographic factors such as age, sex, 17,22 family income, and single-parent status 1, 16,18,29,30”
From Medication Adherence in the MTA: Saliva Methylphenidate Samples Versus Parent Report and Mediating Effect of Concomitant Behavioral Treatment (2009) · cites this paper as [16]
Citations
Cites
Compliance With Medication Regimens for Mental and Physical Disorders
Cramer, J. A., & Rosenheck, R. (1998) · Psychiatric Services · doi:10.1176/ps.49.2.196 · Cited by 725
Blackwell, B. (1973) · New England Journal of Medicine · doi:10.1056/nejm197308022890506 · Cited by 510
HOW WELL DO PATIENTS TAKE ORAL PENICILLIN? A COLLABORATIVE STUDY IN PRIVATE PRACTICE
Charney, E., BYNUM, R. S., Eldredge, D., Frank, D., MacWhinney, J. B., McNabb, N., Scheiner, A. P., Sumpter, E. A., & Iker, H. P. (1967) · PEDIATRICS · doi:10.1542/peds.40.2.188 · Cited by 343
Psychological Factors Associated with Medication Nonadherence in Asthmatic Children
Bender, B., Milgrom, H., Rand, C. S., & Ackerson, L. (1998) · Journal of Asthma · doi:10.3109/02770909809075667 · Cited by 209
Factors associated with children's adherence to stimulant medication
Firestone, P. (1982) · American Journal of Orthopsychiatry · doi:10.1111/j.1939-0025.1982.tb01431.x · Cited by 143
Locus of Control, Social Support, and Adherence to the Diabetes Regimen
Tillotson, L. M., & Smith, M. S. (1996) · The Science of Diabetes Self-Management and Care · doi:10.1177/014572179602200206 · Cited by 142
Matsui, D. M. (1997) · Pediatric Clinics of North America · doi:10.1016/s0031-3955(05)70459-4 · Cited by 129
Compliance with Medical Regimens During Adolescence
Litt, I. F., & Cuskey, W. R. (1980) · Pediatric Clinics of North America · doi:10.1016/s0031-3955(16)33815-9 · Cited by 128
Beck, D. E., Fennell, R. S., Yost, R. L., Robinson, J. D., Geary, D., & Richards, G. A. (1980) · The Journal of Pediatrics · doi:10.1016/s0022-3476(80)80653-6 · Cited by 128
(1981) · Patient Counselling and Health Education · doi:10.1016/s0738-3991(81)80067-5 · Cited by 108
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Research works printed but not linked: 2
- Brown RT, 1985, Psychopharmacol Bull, 21, 28
- Lansky S, 1983, Am J Pediatr Hematol Oncol, 5, 87
Cited by
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Items 101–120 of 120
Medication Adherence: What Adolescents are Saying and What Prescribers Can Do
Townsend, L. D., Gearing, R. E., & Floersch, J. E. (2010) · Child and Adolescent Psychopharmacology News · doi:10.1521/capn.2010.15.2.7 · Cited by 2
Compliance of Herbal Medicine in Children and the Factors Associated with Compliance
Haeng, L. S., & Tae, C. G. (2010) · The Journal of Pediatrics of Korean Medicine · Cited by 2
Psychiatric Evaluation of Children and Adolescents: It Takes Time
Bereiter, J. (2007) · Cited by 1
Feldman, M., Bélanger, S. A., de pédiatrie, S. C., & communautaire, C. D. L. P. (2009) · Paediatrics & Child Health · doi:10.1093/pch/14.9.598 · Cited by 1
“Selon les sondages [25][26][27], près de la moitié des patients à qui on prescrit un stimulant à LI admettent ne pas le prendre.”
BackgroundStubbe, D. E. (2023) · FOCUS The Journal of Lifelong Learning in Psychiatry · doi:10.1176/appi.focus.20230017 · Cited by 1
Placement hors du milieu familial et usage des médicaments psychotropes
Lafortune, D., Meilleur, D., & Bellavance, J. (2011) · Neuropsychiatrie de l Enfance et de l Adolescence · doi:10.1016/j.neurenf.2011.07.002 · Cited by 1
Laurier, C., Collin, J., & Lafortune, D. (2009) · Psychotropes · doi:10.3917/psyt.151.0093 · Cited by 1
“Malgré une forte proportion de mineurs ayant une prescription psy-chopharmacologique, très peu d’études ont porté sur leur observance de la médication psychotrope (Hack & Chow, 2001) ou sur leur expérience personnelle par rapport aux médicaments prescrits.”
Moore, T. R. (2010) · University of Minnesota Digital Conservancy (University of Minnesota) · Cited by 1
Thatcher, D. L., & Clark, D. B. (2005) · Elsevier eBooks · doi:10.1016/b978-012564370-2/50018-0 · Cited by 1
OTHER ARTICLES NOTED (Nov 01 to 18 Oct 02)
(2003) · Evidence-Based Nursing · doi:10.1136/ebn.6.1.e1 · Cited by 1
Gevensleben, H. (2012) · eDiss (Georg-August-Universität Göttingen) · doi:10.53846/goediss-1440
Child psychopharmacology: how much have we progressed?
Grover, S., & Kate, N. (2013) · World Psychiatry · doi:10.1002/wps.20037
“Some initiatives along this line are flourishing in the area of psychosis (7).”
BackgroundDanov, S. E. (2010) · University of Minnesota Digital Conservancy (University of Minnesota)
Alliance and Mechanisms of Medication Adherence in Pediatric Psychiatric Practice
Nadai, D., & Stevens, A. (2013)
Stigma Perceptions of Adolescents with Emotional and/or Behavioral Difficulties
Barraclough, C. (2014) · The Mathematics Enthusiast
(2001) · Human Psychopharmacology Clinical and Experimental · doi:10.1002/hup.277
Principles of High-Quality Pediatric Pharmacotherapy
Joshi, S. V., & Glowinski, A. L. (2023) · Psychiatric Annals · doi:10.3928/00485713-20230613-02
Psychoéducation chez l’enfant et ses parents : les TDAH de Nolan et de sa maman
Piégelin, F. (2024) · Elsevier eBooks · doi:10.1016/b978-2-294-77539-0.00006-2
Metadata
- Authors
- Hack, S., & Chow, B.
- Affiliations
- New York University (US)
- University of California San Diego (US)
- Venue
- Journal of Child and Adolescent Psychopharmacology
- Publisher
- SAGE Publications
- Published
- 2001-03
- Volume
- 11
- Issue
- 1
- Pages
- 59-67
- ISSN
- 1044-5463 (ISSN-L)
- 1557-8992
- OpenAlex
- W1967979227
- Cited by
- 120
- References
- 29
- Citations by year
- 2024: 5 · 2023: 5 · 2021: 1 · 2020: 2 · 2019: 2 · 2018: 4 · 2017: 4 · 2016: 5 · 2015: 1 · 2014: 7 · 2013: 4 · 2012: 5
- FWCI
- 6.87
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Journal of Child and Adolescent Psychopharmacology (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Family Practice › Medication Adherence and Compliance
- Health Sciences › Medicine › Psychiatry and Mental health › Attention Deficit Hyperactivity Disorder
- Health Sciences › Medicine › Pediatrics, Perinatology and Child Health › Pharmaceutical studies and practices
- Keywords
- medication adherence, pediatric psychopharmacology, attention deficit hyperactivity disorder, stimulant medication, treatment alliance, patient education, drug costs, risk and protective factors
- MeSH terms
- Adult, Child, Humans, Patient Compliance, Patient Education as Topic, Psychotropic Drugs
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