Factors associated with children's adherence to stimulant medication
Abstract
Hyperactive children and their families were studied to assess adherence to a regimen of stimulant medication. Of those agreeing to participate for one year, 20% had discontinued medication by the fourth month and 44% by the tenth month. Findings are discussed in relation to child and parent characteristics, and unique nature of using medication to treat behavior problems in children, and the difficulty of carrying out such long-term investigations with children.
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Estimated adherence rates in children with ADHD range from 56% to 75%, and more than half discontinue treatment regardless of efficacy or symptom severity.
“estimated adherence rates in children with ADHD only range from 56% to 75%, 16 and more than 50% of patients with ADHD discontinue treatment regardless of its efficacy or symptom severity.17,18”
From Medication Adherence in the MTA: Saliva Methylphenidate Samples Versus Parent Report and Mediating Effect of Concomitant Behavioral Treatment (2009) · cites this paper as [17]
Unlike some previous studies, this study found no associations between adherence and demographic factors such as age, sex, family income, and single-parent status.
“However, unlike some previous studies, we found no associations between adherence and demographic factors such as age, sex, 17,22 family income, and single-parent status 1, 16,18,29,30”
From Medication Adherence in the MTA: Saliva Methylphenidate Samples Versus Parent Report and Mediating Effect of Concomitant Behavioral Treatment (2009) · cites this paper as [17]
Our data suggest that new drug delivery systems such as SLI381 (Adderall XR) represent a successful strategy to extend the benefits of psychostimulant treatment of ADHD without incurring added side effects, thereby avoiding some compliance issues raised by shorter-acting stimulant preparations.
“Our data suggest new drug delivery systems such as SLI381 (Adderall XR) represent a successful strategy to extend the benefits of psychostimulant treatment of ADHD without incurring added side effects, thereby avoiding some of the compliance issues raised by shorter-acting stimulant preparations (Brown et al., 1987;Firestone, 1982;Kauffman et al., 1981).”
From Analog Classroom Assessment of a Once-Daily Mixed Amphetamine Formulation, SLI381 (ADDERALL XR), in Children With ADHD (2003) · cites this paper as Firestone, 1982
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- Authors
- Firestone, P.
- Corresponding author
- Firestone, Philip
- Venue
- American Journal of Orthopsychiatry
- Published
- 1982-07
- Volume
- 52
- Issue
- 3
- Pages
- 447-457
- ISSN
- 0002-9432 (ISSN-L)
- 1939-0025
- OpenAlex
- W2074782146
- Cited by
- 143
- References
- 35
- Citations by year
- 2026: 1 · 2025: 1 · 2024: 1 · 2023: 2 · 2021: 1 · 2019: 2 · 2018: 1 · 2017: 2 · 2015: 2 · 2014: 2 · 2013: 1 · 2012: 9
- FWCI
- 4.50
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- American Journal of Orthopsychiatry (publishedVersion)
- PubMed (publishedVersion)
- Funders
- Ontario Ministry of Health (DM-304; DM-425)
- Topics
- Health Sciences › Medicine › Family Practice › Medication Adherence and Compliance
- Health Sciences › Medicine › Psychiatry and Mental health › Attention Deficit Hyperactivity Disorder
- Social Sciences › Psychology › Developmental and Educational Psychology › Behavioral and Psychological Studies
- Keywords
- medication adherence, stimulant medication, hyperactivity, attention deficit hyperactivity disorder, children, parents, drug discontinuation, long-term follow-up, behavioral problems
- MeSH terms
- Attention Deficit Disorder with Hyperactivity, Behavior Therapy, Child, Female, Humans, Male, Methylphenidate, Patient Compliance, Psychological Tests
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