Redox regulation of cell survival

Trachootham, Dunyaporn, Lu, Weiqin, Ogasawara, Marcia A., Valle, Nilsa Rivera-Del, Huang, Peng·2008·Antioxidants & Redox Signaling

Cites (354)

Items 201–354 of 354

  1. Stress-Responsive Protein Kinases in Redox-Regulated Apoptosis Signaling
    Atsushi Matsuzawa, Hidenori Ichijo · 2005 · Antioxidants and Redox Signaling
  2. Genetic Evidence that Small Maf Proteins Are Essential for the Activation of Antioxidant Response Element-Dependent Genes
    Fumiki Katsuoka, Hozumi Motohashi, Tetsuro Ishii, Hiroyuki Aburatani, James Douglas Engel, Masayuki P. Yamamoto · 2005 · Molecular and Cellular Biology
  3. Apoptosis-based therapies and drug targets
    Ute Fischer, Klaus Schulze‐Osthoff · 2005 · Cell Death and Differentiation
  4. Mitochondrial Manganese-Superoxide Dismutase Expression in Ovarian Cancer
    Yu-Min Hu, D. Rosen, Yan Zhou, Li Feng, Gong Yang, Jin-Song Liu, Peng Huang · 2005 · Journal of Biological Chemistry
  5. BCR/ABL oncogenic kinase promotes unfaithful repair of the reactive oxygen species–dependent DNA double-strand breaks
    Michal Oskar Nowicki, Rafal Falinski, Mateusz Koptyra, Artur Słupianek, Tomasz Stokłosa, Ewa Gloc, Margaret Nieborowska-Skorska, Janusz Błasiak, Tomasz Skórski · 2004 · Blood
  6. ReviewRegulation of protein function by glutathionylation
    Pietro Ghezzi · 2005 · Free Radical Research
  7. S-Nitrosylation-dependent Inactivation of Akt/Protein Kinase B in Insulin Resistance
    Takashi Yasukawa, Eriko Tokunaga, Hidetaka Ota, Hiroki Sugita, J. A. Jeevendra Martyn, Masao Kaneki · 2005 · Journal of Biological Chemistry
  8. Oxidative stress and TNF-a induce histone Acetylation and NF-кB/AP-1 activation in Alveolar epithelial cells: Potential mechanism In gene transcription in lung inflammation
    Irfan Rahman, Peter S. Gilmour, Luis Albert Jimenez, William MacNee · 2002 · Springer eBooks
  9. Role of Glutaredoxin in Metabolic Oxidative Stress
    Jae Jin Song, Juong G. Rhee, Mohan Suntharalingam, Susan A. Walsh, Douglas R. Spitz, Yong Jun Lee · 2002 · Journal of Biological Chemistry
  10. Mitochondrial Reactive Oxygen Species Activation of p38 Mitogen-Activated Protein Kinase Is Required for Hypoxia Signaling
    Brooke M. Emerling, Leonidas C. Platanias, Emma V. I. Black, Ángel R. Nebreda, Roger J. Davis, Navdeep S. Chandel · 2005 · Molecular and Cellular Biology
  11. Lipoxidation products as biomarkers of oxidative damage to proteins during lipid peroxidation reactions
    Jesús R. Requena, Min-Xin Fu, Mushtaq Ahmed, Alicia Josephine Jenkins, Timothy J. Lyons, Susan R. Thorpe · 1996 · Nephrology Dialysis Transplantation
  12. Reactive Oxygen Species and Regulation of Gene Expression
    Kyril T. Turpaev · 2002 · Biochemistry (Moscow)
  13. WT p53, but Not Tumor-derived Mutants, Bind to Bcl2 via the DNA Binding Domain and Induce Mitochondrial Permeabilization
    York A. Tomita, N D Marchenko, Susan H. Erster, Alice Nemajerová, Alexander Dehner, Christian Klein, Hongguang Pan, Horst Kessler, Petr Pančoška, Ute Martha Moll · 2006 · Journal of Biological Chemistry
  14. Nitric oxide negatively regulates c-Jun N-terminal kinase/stress-activated protein kinase by means of S -nitrosylation
    Hee-Sae Park, Sung‐Ho Huh, Mi-Sung Kim, Soo‐Hwan Lee, Eui‐Ju Choi · 2000 · Proceedings of the National Academy of Sciences
  15. Blockade of Histone Deacetylase Inhibitor-Induced RelA/p65 Acetylation and NF-κB Activation Potentiates Apoptosis in Leukemia Cells through a Process Mediated by Oxidative Damage, XIAP Downregulation, and c-Jun N-Terminal Kinase 1 Activation
    Yun Dai, Mohamed Rahmani, Paul Dent, Steven Grant · 2005 · Molecular and Cellular Biology
  16. Effects of age and caloric restriction on glutathione redox state in mice
    Igor Rebrin, Sergey Kamzalov, Rajindar S. Sohal · 2003 · Free Radical Biology and Medicine
  17. Mitochondrial membrane permeabilization: the sine qua non for cell death
    Jeffrey S. Armstrong · 2006 · BioEssays
  18. Transgenic Mice Overexpressing Glutathione Peroxidase 4 Are Protected against Oxidative Stress-induced Apoptosis*
    Qi-Tao Ran, Han-Yu Liang, Minjun Gu, W. Qi, C. Walter, L. Roberts, B. Herman, A. Richardson, H. Van Remmen · 2004 · Journal of Biological Chemistry
  19. p53 and Metabolism: Inside the TIGAR
    Douglas R. Green, Jerry E. Chipuk · 2006 · Cell
  20. Oxidative stress and TNF-α induce histone acetylation and NF-κB/AP-1 activation in alveolar epithelial cells: Potential mechanism in gene transcription in lung inflammation
    Irfan Rahman, Peter S. Gilmour, Luis Albert Jimenez, William MacNee · 2002 · Molecular and Cellular Biochemistry
  21. S -Nitrosylation: NO-Related Redox Signaling to Protect Against Oxidative Stress
    Junhui Sun, Charles Steenbergen, Elizabeth Murphy · 2006 · Antioxidants and Redox Signaling
  22. The mitochondrial theory of aging and its relationship to reactive oxygen species damage and somatic mtDNA mutations
    Lawrence A. Loeb, Douglas C. Wallace, George M. Martin · 2005 · Proceedings of the National Academy of Sciences
  23. JNK Signalling: A Possible Target to Prevent Neurodegeneration
    Tiziana Borsello, Gianluigi Forloni · 2007 · Current Pharmaceutical Design
  24. Coordinate Regulation of IκB Kinases by Mitogen-Activated Protein Kinase Kinase Kinase 1 and NF-κB-Inducing Kinase
    Shino Nemoto, Joseph A. DiDonato, Anning Lin · 1998 · Molecular and Cellular Biology
  25. Shift of the Cellular Oxidation‐Reduction Potential in Neural Cells Expressing Bcl‐2
    Lisa Ellerby, H. Michael Ellerby, Sunghi M. Park, Anne L. Holleran, Anne N. Murphy, Gary M. Fiskum, Darci J. Kane, Maria Pia Testa, Çelík Kayalar, Dale E. Bredesen · 1996 · Journal of Neurochemistry
  26. The Importance of Proteins in Defense Against Oxidation
    Bourdon, Emmanuel, Blache, Denis · 2001 · Antioxidants & Redox Signaling
  27. Protection against Cisplatin-Induced Toxicities by N-Acetylcysteine and Sodium Thiosulfate as Assessed at the Molecular, Cellular, and in Vivo Levels
    D. Thomas Dickey, Y. Jeffrey Wu, Leslie L. Muldoon, Edward A. Neuwelt · 2005 · Journal of Pharmacology and Experimental Therapeutics
  28. Mitogen-activated protein kinase pathways in redox signaling
    Martine Torrès · 2003 · Frontiers in bioscience
  29. Narrative Review: Protein Degradation and Human Diseases: The Ubiquitin Connection
    Eyal Reinstein, Aaron J. Ciechanover · 2006 · Annals of Internal Medicine
  30. Neuronal Life-and-Death Signaling, Apoptosis, and Neurodegenerative Disorders
    Mark P. Mattson · 2006 · Antioxidants and Redox Signaling
  31. Role of cardiolipin in cytochrome c release from mitochondria
    Martin Ott, Boris Zhivotovsky, Sten Orrenius · 2007 · Cell Death and Differentiation
  32. c-Myc Phosphorylation Is Required for Cellular Response to Oxidative Stress
    Barbara Benassi, Maurizio Fanciulli, Francesco Fiorentino, Alessandro Porrello, Giovanna Chiorino, Massimo F. Loda, Gabriella Zupi, Annamaria Biroccio · 2006 · Molecular Cell
  33. N-acetylcysteine and neurodegenerative diseases: Basic and clinical pharmacology
    Motoki Arakawa, Yoshihisa Ito · 2007 · The Cerebellum
  34. Human p53 Is Inhibited by Glutathionylation of Cysteines Present in the Proximal DNA-Binding Domain during Oxidative Stress,
    Chinavenmeni Subramani Velu, Suryakant K. Niture, Catalin E. Doneanu, Nagarajan Pattabiraman, Kalkunte S. Srivenugopal · 2007 · Biochemistry
  35. Improvement of the Therapeutic Index of Anticancer Drugs by the Superoxide Dismutase Mimic Mangafodipir
    Jérôme Alexandre, Carole Nicco, Christiane Chéreau, Alexis Laurent, Bernard J. Weill, François Goldwasser, Frédéric Batteux · 2006 · JNCI Journal of the National Cancer Institute
  36. Oxidative stress inhibits MEKK1 by site-specific glutathionylation in the ATP-binding domain
    Janet V. Cross, Dennis J. Templeton · 2004 · Biochemical Journal
  37. A genomic screen for activators of the antioxidant response element
    Liu, Yanxia, Kern, Jonathan T., Walker, John R., Johnson, Jeffrey A., Schultz, Peter G., Luesch, Hendrik · 2007 · Proceedings of the National Academy of Sciences
  38. Role of 4-hydroxynonenal in stress-mediated apoptosis signaling
    Sanjay Awasthi, Rajendra Sharma, Ji Zhong Cheng, Yusong Yang, Abha Sharma, Sharad S. Singhal, Sanjay Awasthi · 2003 · Molecular Aspects of Medicine
  39. Redox regulation of the hypoxia-inducible factor
    Pouysségur, Jacques, Mechta-Grigoriou, Fatima · 2006 · Biological Chemistry
  40. Role of Reactive Oxygen Intermediates in Activation-induced CD95 (APO-1/Fas) Ligand Expression
    Manuel K.A. Bauer, Markus Vogt, Marek Łoś, Johanna Siegel, Sebastian Wesselborg, Klaus Schulze‐Osthoff · 1998 · Journal of Biological Chemistry
  41. Redox regulation of PTEN and protein tyrosine phosphatases in H2O2‐mediated cell signaling
    Seung-Hyun Cho, Chang‐Hun Lee, Younghee Ahn, Hyun‐Jung Kim, Hoeon Kim, Chiyoung Ahn, Kap‐Seok Yang, Seung-Rock Lee · 2004 · FEBS Letters
  42. Zinc Binding and Redox Control of p53 Structure and Function
    Pierre L. Hainaut, Kristine Mann · 2001 · Antioxidants and Redox Signaling
  43. Hydrogen peroxide activates IκB kinases through phosphorylation of serine residues in the activation loops
    Hideaki Kamata, Tomoyuki Manabe, Shinichi Oka, Keiko Kamata, Hajime Hirata · 2002 · FEBS Letters
  44. Apoptotic interactions of cytochrome c: Redox flirting with anionic phospholipids within and outside of mitochondria
    Bayir, H., Fadeel, B., Palladino, M.J., Witasp, E., Kurnikov, I.V., Tyurina, Y.Y., Tyurin, V.A., Amoscato, A.A., Jiang, J., Kochanek, P.M. et al. · 2006 · Biochimica et Biophysica Acta (BBA) - Bioenergetics
  45. Effect of Altered Redox States on Expression and DNA-Binding Activity of Hypoxia-Inducible Factor 1
    G.L. Wang, Bing‐Hua Jiang, Gregg L. Semenza · 1995 · Biochemical and Biophysical Research Communications
  46. Oxidative signaling pathway for externalization of plasma membrane phosphatidylserine during apoptosis
    Valerian E. Kagan, James P. Fabisiak, Anna A. Shvedova, Yulia Y. Tyurina, Vladimir A. Tyurin, Nina Felice Schor, Kazuaki Kawai · 2000 · FEBS Letters
  47. Disulfide Bond-mediated Multimerization of Ask1 and Its Reduction by Thioredoxin-1 Regulate H2O2-induced c-Jun NH2-terminal Kinase Activation and Apoptosis
    Philippe J. Nadeau, Steve J. Charette, Michel B. Tolédano, Jacques Landry · 2007 · Molecular Biology of the Cell
  48. Glutathiolation Regulates Tumor Necrosis Factor-α–Induced Caspase-3 Cleavage and Apoptosis
    Shi Pan, Bradford C. Berk · 2006 · Circulation Research
  49. A Fenton reaction at the endoplasmic reticulum is involved in the redox control of hypoxia-inducible gene expression
    Liu, Qing, Berchner-Pfannschmidt, Utta, Möller, Ulrike, Brecht, Martina, Wotzlaw, Christoph, Acker, Helmut, Jungermann, Kurt, Kietzmann, Thomas · 2004 · Proceedings of the National Academy of Sciences
  50. Oxidative modification of H-ras: S-thiolation and S-nitrosylation of reactive cysteines
    Robert J. Mallis, Janice E. Buss, James A. Thomas · 2001 · Biochemical Journal
  51. Requirement for Rac1 in a K-ras–Induced Lung Cancer in the Mouse
    Joseph L. Kissil, Marita J. Walmsley, Linda Hanlon, Kevin M. Haigis, Carla F. Bender Kim, Alejandro Sweet-Cordero, Matthew S. Eckman, David Arthur Tuveson, Anthony J. Capobianco, Victor L. J. Tybulewicz et al. · 2007 · Cancer Research
  52. Neuroprotection by S ‐nitrosoglutathione of brain dopamine neurons from oxidative stress
    Pekka Veli Rauhala, Anya Maan‐Yuh Lin, Chuang C. Chiueh · 1998 · The FASEB Journal
  53. Redox modulation of cellular signaling and metabolism through reversible oxidation of methionine sensors in calcium regulatory proteins
    Diana J. Bigelow, Thomas C. Squier · 2004 · Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics
  54. Axis determination by inhibition of Wnt signaling in Xenopus
    Ken Itoh, Sergei Y. Sokol · 1999 · Genes & Development
  55. Regulation of Signal Transduction Through Protein Cysteine Oxidation
    Janet V. Cross, Dennis J. Templeton · 2006 · Antioxidants and Redox Signaling
  56. S-Nitrosothiols signal hypoxia-mimetic vascular pathology
    Lisa A. Palmer, Allan Doctor, Preeti Chhabra, Mary Lynn Sheram, Victor E. Laubach, Molly Z Karlinsey, Michael S. Forbes, Timothy L. Macdonald, Benjamin M Gaston · 2007 · Journal of Clinical Investigation
  57. The p53-induced Gene-6 (Proline Oxidase) Mediates Apoptosis through a Calcineurin-dependent Pathway
    Armando M Rivera, Steven A. Maxwell · 2005 · Journal of Biological Chemistry
  58. Nitric Oxide-induced Transcriptional Up-regulation of Protective Genes by Nrf2 via the Antioxidant Response Element Counteracts Apoptosis of Neuroblastoma Cells
    Saravanakumar Dhakshinamoorthy, Alan George Porter · 2004 · Journal of Biological Chemistry
  59. Bcl-2 prevents mitochondrial permeability transition and cytochrome c release via maintenance of reduced pyridine nucleotides
    Alicia Juliana Kowaltowski, Aníbal Eugênio Vercesi, Gary M. Fiskum · 2000 · Cell Death and Differentiation
  60. Nitric Oxide Inhibits c-Jun DNA Binding by Specifically TargetedS-Glutathionylation
    Peter Klatt, Estela Pineda‐Molina, Santiago Lamas · 1999 · Journal of Biological Chemistry
  61. The Dual Roles of Nutrients as Antioxidants and Prooxidants: Their Effects on Tumor Cell Growth
    JOEL L. SCHWARTZ · 1996 · Journal of Nutrition
  62. Tumor Promoter Arsenite Activates Extracellular Signal-Regulated Kinase through a Signaling Pathway Mediated by Epidermal Growth Factor Receptor and Shc
    Wei Chen, Jennifer L. Martindale, Nikki J. Holbrook, Liu Y · 1998 · Molecular and Cellular Biology
  63. Two different cellular redox systems regulate the DNA-binding activity of the p50 subunit of NF-κB in vitro
    Katsuyuki Mitomo, Nakayama Kohzo, Fujimoto Kotaro, Sun Xiangao, Seki Shuji, Ken-ichi Yamamoto · 1994 · Gene
  64. Regulation of gene expression by transcription factor acetylation
    Andrew J. Bannister, Eric Alexander Miska · 2000 · Cellular and Molecular Life Sciences
  65. ReviewPTPs versus PTKs: The redox side of the coin
    Paola Chiarugi · 2005 · Free Radical Research
  66. The Redox Regulation of PI 3-Kinase–Dependent Signaling
    Nicholas R. Leslie · 2006 · Antioxidants and Redox Signaling
  67. Repression of Sestrin Family Genes Contributes to Oncogenic Ras-Induced Reactive Oxygen Species Up-regulation and Genetic Instability
    Pavel Kopnin, Larissa S. Agapova, Boris P. Kopnin, Peter M. Chumakov · 2007 · Cancer Research
  68. Inactivation of wild-type p53 protein function by reactive oxygen and nitrogen species in malignant glioma cells.
    Charles Cobbs, Thomas R. Whisenhunt, Duane R. Wesemann, Lualhati E. Harkins, Erwin G. Van Meir, Minu Samanta · 2003 · PubMed
  69. Age-associated decline in γ-glutamylcysteine synthetase gene expression in rats
    Rui-Ming Liu, Jinah Choi · 2000 · Free Radical Biology and Medicine
  70. Melatonin, Aging, and Age-Related Diseases: Perspectives for Prevention, Intervention, and Therapy
    Burkhard Pöeggeler · 2005 · Endocrine
  71. Pag, a Putative Tumor Suppressor, Interacts with the Myc Box II Domain of c-Myc and Selectively Alters Its Biological Function and Target Gene Expression
    Z M Mu, Xiao Ying Yin, Edward V. Prochownik · 2002 · Journal of Biological Chemistry
  72. Activation of Antioxidant Pathways in Ras-Mediated Oncogenic Transformation of Human Surface Ovarian Epithelial Cells Revealed by Functional Proteomics and Mass Spectrometry
    Travis W. Young, Fang C. Mei, Gong She Yang, Jennifer A. Thompson-Lanza, Jinsong Liu, Xiaodong Cheng · 2004 · Cancer Research
  73. Production of DNA Strand Breaks in Vitro and Reactive Oxygen Species in Vitro and in HL-60 Cells by PCB Metabolites
    AR Srinivasan, Hans‐Joachim Lehmler, Larry W. Robertson · 2001 · Toxicological Sciences
  74. Extracellular 8-oxo-dG as a sensitive parameter for oxidative stress in vivo and in vitro
    Siamak Haghdoost, Stefan Czene, Ingemar Näslund, Sven Skog, Mats Harms‐Ringdahl · 2005 · Free Radical Research
  75. Activation pattern of mitogen‐activated protein kinases elicited by peroxynitrite: attenuation by selenite supplementation
    Stefan M. Schieke, Karlis Briviba, Lars‐Oliver Klotz, Helmut Sies · 1999 · FEBS Letters
  76. Nrf2 Transcriptionally Activates the mafG Gene through an Antioxidant Response Element
    Fumiki Katsuoka, Hozumi Motohashi, James Douglas Engel, Masayuki P. Yamamoto · 2004 · Journal of Biological Chemistry
  77. Effect of Cytochrome c on the Generation and Elimination of O<mml:math xmlns:mml="http://www.w3.org/1998/Math/MathML" altimg="si1.gif"><mml:msubsup><mml:mrow/><mml:mrow><mml:mn>2</mml:mn></mml:mrow><mml:mrow><mml:mo>⨪</mml:mo></mml:mrow></mml:msubsup></mml:math> and H2O2 in Mitochondria
    Zhao, Yungang, Wang, Zhi-Bo, Xu, Jian-Xing · 2003 · Journal of Biological Chemistry
  78. The Role of the NADPH Oxidase Complex, p38 MAPK, and Akt in Regulating Human Monocyte/Macrophage Survival
    Yijie Wang, Mandy M. Zeigler, Gregory K. Lam, Melissa G Hunter, Timothy D. Eubank, Valery V. Khramtsov, Susheela Tridandapani, Chandan K. Sen, Clay B. Marsh · 2006 · American Journal of Respiratory Cell and Molecular Biology
  79. Redox-sensitive regulation of the HIF pathway under non-hypoxic conditions in pulmonary artery smooth muscle cells
    BelAiba, R. S., Djordjevic, T., Bonello, S., Flügel, D., Hess, J., Kietzmann, T., Görlach, A. · 2004 · Biological Chemistry
  80. Oxidized low-density lipoprotein (oxLDL) triggers hypoxia-inducible factor-1α (HIF-1α) accumulation via redox-dependent mechanisms
    Vladimir A. Shatrov, Vadim V. Sumbayev, Jie Zhou, Bernhard Brüne · 2003 · Blood
  81. Nitrosylation of Cytochrome c during Apoptosis
    Christopher M. Schonhoff, Benjamin M Gaston, Joan B. Mannick · 2003 · Journal of Biological Chemistry
  82. Proteasomal Defense of Oxidative Protein Modifications
    Diana Poppek, Tilman Grune · 2006 · Antioxidants and Redox Signaling
  83. Nitric oxide stimulates heme oxygenase-1 gene transcription via the Nrf2/ARE complex to promote vascular smooth muscle cell survival
    X LIU, Kelly J. Peyton, Diana Ensenat, H WANG, M HANNINK, J Alam, William Durante · 2007 · Cardiovascular Research
  84. Subcellular compartmentalization of glutathione: Correlations with parameters of oxidative stress related to genotoxicity
    R. M.Green, M. Graham, Michael R. O’Donovan, James Kevin Chipman, Nikolas John Hodges · 2006 · Mutagenesis
  85. Regulation of MAP kinase-dependent apoptotic pathway: implication of reactive oxygen and nitrogen species
    Vadim V. Sumbayev, Inna M. Yasinska · 2005 · Archives of Biochemistry and Biophysics
  86. NO restores HIF-1α hydroxylation during hypoxia: Role of reactive oxygen species
    Melvin Callapina, Jie Zhou, Tobias Schmid, Roman Köhl, Bernhard Brüne · 2005 · Free Radical Biology and Medicine
  87. Redox Aspects of Bcl-2 Function
    David W. Voehringer, Raymond E. Meyn · 2000 · Antioxidants and Redox Signaling
  88. Direct oxidative modifications of signalling proteins in mammalian cells and their effects on apoptosis
    Karen England, Thomas G. Cotter · 2005 · Redox Report
  89. Hypoxia in cancer cell metabolism and pH regulation
    M. Christiane Brahimi-Horn, Jacques Pouysségur · 2007 · Essays in Biochemistry
  90. Nrf2 regulates the sensitivity of death receptor signals by affecting intracellular glutathione levels
    Naoki Morito, Keigyou Yoh, Ken Itoh, Aki Hirayama, Akio Kôyama, Masayuki P. Yamamoto, Satoru Takahashi · 2003 · Oncogene
  91. Enhanced skin carcinogenesis in transgenic mice with high expression of glutathione peroxidase or both glutathione peroxidase and superoxide dismutase.
    Yingqing Lu, You Rong Lou, P Yen, Harold L. Newmark, Oleg Mirochnitchenko, Masayori Inouye, Mou‐Tuan Huang · 1997 · PubMed
  92. The Role of Nitric Oxide (NO) in Stability Regulation of Hypoxia Inducible Factor-1α (HIF-1α)
    Bernhard Brüne, Jie Zhou · 2003 · Current Medicinal Chemistry
  93. Mitochondrial DNA and ageing
    Aleksandra Trifunović · 2006 · Biochimica et Biophysica Acta (BBA) - Bioenergetics
  94. Does the redox status of cytochrome C act as a fail-safe mechanism in the regulation of programmed cell death?
    John T. Hancock, Radhika Desikan, Steven J. Neill · 2001 · Free Radical Biology and Medicine
  95. Rapid and selective death of leukemia stem and progenitor cells induced by the compound 4-benzyl, 2-methyl, 1,2,4-thiadiazolidine, 3,5 dione (TDZD-8)
    Mónica L. Guzmán, Xiaojie Li, Cheryl A. Corbett, Randall M. Rossi, Timothy P. Bushnell, Jane L. Liesveld, Josée Hébert, Fay M. Young, Craig T. Jordan · 2007 · Blood
  96. Induction of Glutathione Synthesis in Macrophages by Oxidized Low-Density Lipoproteins Is Mediated by Consensus Antioxidant Response Elements
    Florian Bea, Francesca N. Hudson, Alan Chait, Terrance J. Kavanagh, Michael E. Rosenfeld · 2003 · Circulation Research
  97. Aconitase is the main functional target of aging in the citric acid cycle of kidney mitochondria from mice
    Connie S. Yarian, Dikran Toroser, Rajindar S. Sohal · 2005 · Mechanisms of Ageing and Development
  98. Genetic Inactivation of RelA/p65 Sensitizes Adult Mouse Hepatocytes to TNF-induced Apoptosis In Vivo and In Vitro
    Fabian Geisler, Hana Algül, Stephan A Paxian, Roland Michael Schmid · 2007 · Gastroenterology
  99. Oxidized lipoproteins may play a role in neuronal cell death in Alzheimer disease
    Bozena Draczynska‐Lusiak, Ann Doung, Albert Y. Sun · 1998 · Molecular and Chemical Neuropathology
  100. SLCO/OATP-like Transport of Glutathione in FasL-induced Apoptosis
    Rodrigo Franco, John Anthony Cidlowski · 2006 · Journal of Biological Chemistry
  101. Redox Regulation of PTEN by S-Nitrosothiols
    Chang‐Xi Yu, Sheng Li, A. Richard Whorton · 2005 · Molecular Pharmacology
  102. Nutritional intervention in brain aging: reducing the effects of inflammation and oxidative stress.
    Francis C. Lau, Barbara Shukitt‐Hale, James A. Joseph · 2007 · PubMed
  103. Significance of error‐avoiding mechanisms for oxidative DNA damage in carcinogenesis
    Teruhisa Tsuzuki, Yoshimichi Nakatsu, Yusaku Nakabeppu · 2007 · Cancer Science
  104. Nitric Oxide Inhibits Peroxidase Activity of Cytochrome c· Cardiolipin Complex and Blocks Cardiolipin Oxidation
    Irina I. Vlasova, Vladimir A. Tyurin, Alexandr A. Kapralov, Igor V. Kurnikov, Anatoly N. Osipov, M. V. Potapovich, Detcho A. Stoyanovsky, Valerian E. Kagan · 2006 · Journal of Biological Chemistry
  105. Activation of p53 by Oxidative Stress Involves Platelet-derived Growth Factor-β Receptor-mediated Ataxia Telangiectasia Mutated (ATM) Kinase Activation
    Chen, Kai, Albano, Adam, Ho, Alan, Keaney, John F. · 2003 · Journal of Biological Chemistry
  106. Nutritional Intervention in Brain Aging
    Francis C. Lau, Barbara Shukitt‐Hale, James A. Joseph · 2007 · Sub-cellular biochemistry/Subcellular biochemistry
  107. HIF-1-Regulated Glucose Metabolism: A Key to Apoptosis Resistance?
    Simone Fulda, Klaus‐Michael Debatin · 2007 · Cell Cycle
  108. Activation of Maf/AP-1 Repressor Bach2 by Oxidative Stress Promotes Apoptosis and Its Interaction with Promyelocytic Leukemia Nuclear Bodies
    Akihiko Muto, Satoshi Tashiro, Haruka Tsuchiya, Akihiro Kume, Masamoto Kanno, Etsuro Ito, Masayuki P. Yamamoto, Kazuhiko Igarashi · 2002 · Journal of Biological Chemistry
  109. The antiapoptotic effect of fibroblast growth factor-2 is mediated through nuclear factor-κB activation induced via interaction between Akt and IκB kinase-β in breast cancer cells
    Franck Vandermoere, Ikram El Yazidi‐Belkoura, Éric Adriaenssens · 2005 · Oncogene
  110. Hydrogen Peroxide Has Opposing Effects on IKK Activity and I κ B α Breakdown in Airway Epithelial Cells
    Ilona Jaspers, Wenli Zhang, Alison Fraser, James M. Samet, William Reed · 2001 · American Journal of Respiratory Cell and Molecular Biology
  111. Complex Functions of AP-1 Transcription Factors in Differentiation and Survival of PC12 Cells
    Sirpa Leppä, Minna R. Eriksson, Rainer Saffrich, Wilhelm J. Ansorge, Dirk Bohmann · 2001 · Molecular and Cellular Biology
  112. Mitochondrial oxygen sensing: regulation of hypoxia-inducible factor by mitochondrial generated reactive oxygen species
    Bell, Eric L., Chandel, Navdeep S. · 2007 · Essays in Biochemistry
  113. Do Antioxidants Interfere With Radiation Therapy for Cancer?
    Ralph W. Moss · 2007 · Integrative Cancer Therapies
  114. Apoptosis signal regulating kinase-1 connects reactive oxygen species to p38 MAPK-induced mitochondrial apoptosis in UVB-irradiated human keratinocytes
    An Van Laethem, Kris Nys, Sofie Van Kelst, Sofie Claerhout, Hidenori Ichijo, Jackie R. Vandenheede, Marjan Garmyn, Patrizia Agostinis · 2006 · Free Radical Biology and Medicine
  115. Activation of Nuclear Factor (Erythroid-2 Like) Factor 2 by Toxic Bile Acids Provokes Adaptive Defense Responses to Enhance Cell Survival at the Emergence of Oxidative Stress
    Kah Poh Tan, Mingdong Yang, Shinya Ito · 2007 · Molecular Pharmacology
  116. Organ-Specific Increase in Mutation Accumulation and Apoptosis Rate in CuZn-Superoxide Dismutase–Deficient Mice
    Rita A. Busuttil, Ana Maria Garcı́a, Carlos Cabrera, Armando Rodriguez, Yousin Suh, Woo Ho Kim, Ting‐Ting Huang, Jan Vijg · 2005 · Cancer Research
  117. Targeting Antioxidants to Mitochondria: A Potential New Therapeutic Strategy for Cardiovascular Diseases
    Víctor M. Víctor, Milagros Rocha · 2007 · Current Pharmaceutical Design
  118. Probing p53 biological functions through the use of genetically engineered mouse models
    Laura Donatella Attardi, Lawrence A. Donehower · 2005 · Mutation research. Fundamental and molecular mechanisms of mutagenesis
  119. c-Jun NH2-Terminal Kinase/c-Jun Signaling Promotes Survival and Metastasis of B Lymphocytes Transformed byTheileria
    Regina Lizundia, Marie Chaussepied, Michel Huerre · 2006 · Cancer Research
  120. Oxidant-induced apoptosis in cultured human retinal pigment epithelial cells.
    Jiyang Cai, Mian Wu, Kasey C. Nelson, P Sternberg, Dean P. Jones · 1999 · PubMed
  121. MEKK1 Mediates the Ubiquitination and Degradation of c-Jun in Response to Osmotic Stress
    Yan Xia, Ji Wang, Shuichan Xu, Gary L. Johnson, Tony R. Hunter, Zhimin Lu · 2006 · Molecular and Cellular Biology
  122. Redox-sensitive signaling factors as a novel molecular targets for cancer therapy
    J. Daniel Pennington, Tony J. C. Wang, Phuongmai Nguyen, Lunching Sun, Kheem Singh Bisht, Dee Dee Smart, David R. Gius · 2005 · Drug Resistance Updates
  123. Evidence for Peroxynitrite-Mediated Modifications to p53 in Human Gliomas: Possible Functional Consequences
    Charles Cobbs, Minu Samanta, Lualhati E. Harkins, G. Yancey Gillespie, Bruce Alex Merrick, Lee Ann MacMillan-Crow · 2001 · Archives of Biochemistry and Biophysics
  124. Single-nucleotide polymorphisms at the TP53-binding or responsive promoter regions of BAX and BCL2 genes and risk of squamous cell carcinoma of the head and neck
    Kexin Chen, Z. Hu, Lie Wang, Erich M. Sturgis, Adel K. El‐Naggar, Weinan Zhang, Qingyi Wei · 2007 · Carcinogenesis
  125. C-Myc Down-Regulation Increases Susceptibility to Cisplatin through Reactive Oxygen Species-Mediated Apoptosis in M14 Human Melanoma Cells
    Annamaria Biroccio, Barbara Benassi, Sarah Amodei, Chiara Gabellini, Donatella Del Bufalo, Gabriella Zupi · 2001 · Molecular Pharmacology
  126. A dominant role for the c-Jun NH2-terminal kinase in oncogenic ras-induced morphologic transformation of human lung carcinoma cells.
    L Xiao, Wenhua Lang · 2000 · PubMed
  127. c-Jun Downregulation by HDAC3-Dependent Transcriptional Repression Promotes Osmotic Stress-Induced Cell Apoptosis
    Yan Xia, Ji Wang, Ta-Jen Liu, W.K. Alfred Yung, Tony R. Hunter, Zhimin Lu · 2007 · Molecular Cell
  128. Nrf2 is an inhibitor of the Fas pathway as identified by Achilles' Heel Method, a new function-based approach to gene identification in human cells
    Kotlo U. Kumar, Furma Yehiely, Elena V. Efimova, Heather Harasty, Bahar Hesabi, Ksenya Shchors, Paz Einat, Ada Rozen, Eva Berent, Louis P. Deiss · 2003 · Oncogene
  129. Characterization of baculovirus recombinant wild‐type p53
    Christian Delphin, Pierre CAHEN, Jean‐Jacques Lawrence, Jacques Baudier · 1994 · European Journal of Biochemistry
  130. ReviewPost-translational disulfide modifications in cell signaling—role of inter-protein, intra-protein, S-glutathionyl, and S-cysteaminyl disulfide modifications in signal transmission
    Catherine A. O’Brian, Feng Chu · 2005 · Free Radical Research
  131. CD95-mediated murine hepatic apoptosis requires an intact glutathione status
    Hannes Hentze, Gerald Künstle, Christiane Volbracht · 1999 · Hepatology
  132. Phosphatidylinositol 3-Kinase/Akt Positively Regulates Fas (CD95)-Mediated Apoptosis in Epidermal Cl41 Cells
    Bin Lu, Liying Wang, Christian Stehlik · 2006 · The Journal of Immunology
  133. Kinetic analysis of copper-induced peroxidation of LDL
    Ilya Pinchuk, Edit Schnitzer, Dov A. Lichtenberg · 1998 · Biochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism
  134. Regulation of cys-based protein tyrosine phosphatases via reactive oxygen and nitrogen species in mast cells and basophils
    Heneberg, P., Draber, P. · 2005 · Current Medicinal Chemistry
  135. Nitric oxide-induced carbonylation of Bcl-2, GAPDH and ANT precedes apoptotic events in insulin-secreting RINm5F cells
    Gladys Margot Cahuana, Juan Rigoberto Tejedo, Juan Jiménez, Remedios Ramı́rez, Francisco Sobrino, Francisco Javier Bedoya · 2003 · Experimental Cell Research
  136. Antioxidants prevent oxidative DNA damage and cellular transformation elicited by the over-expression of c-MYC
    Sagun KC, Juan M. Cárcamo, David W. Golde · 2005 · Mutation research. Fundamental and molecular mechanisms of mutagenesis
  137. Myc Down-Regulation Sensitizes Melanoma Cells to Radiotherapy by Inhibiting MLH1 and MSH2 Mismatch Repair Proteins
    Barbara Bucci, Igea D’Agnano, Donatella Amendola, Arianna Citti, Giorgio Hamid Raza, Roberto Miceli, Ugo De Paula, Rodolfo Marchese, Sonia Albini, Armando Felsani et al. · 2005 · Clinical Cancer Research
  138. Molecular Physics
    Wolfgang Demtröder · 2005 · Wiley eBooks
  139. Ros-Induced Histone Modifications and their Role in Cell Survival and Cell Death
    Terrence J. Monks, Ruiyu Xie, Kulbhushan Tikoo, Serrine S. Lau · 2006 · Drug Metabolism Reviews
  140. Reactive Nitrogen Species-Induced Cell Death Requires Fas-Dependent Activation of c-Jun N-Terminal Kinase
    Punya Shrivastava, Cristen Pantano, Richard Watkin, Brian McElhinney, Amy S. Guala, Matthew E. Poynter, Rebecca L. Persinger, Ralph C. Budd, Yvonne M. W. Janssen-Heininger · 2004 · Molecular and Cellular Biology
  141. Posttranslational modifications of Bcl2 family members-a potential therapeutic target for human malignancy
    Aruna Basu · 2006 · Frontiers in bioscience
  142. MEK kinase 1 mediates the antiapoptotic effect of the Bcr-Abl oncogene through NF-κB activation
    Ryouhei Nawata, Toshiaki Yujiri, Yukinori Nakamura, Koichi Ariyoshi, Toru Takahashi, Yutaka Satō, Yoshitomo Oka, Yukio Tanizawa · 2003 · Oncogene
  143. Bcr-Abl and inhibition of apoptosis in chronic myelogenous leukemia cells
    José L. Fernández-Luna · 2000 · APOPTOSIS
  144. Regulation of the gluconeogenic phosphoenolpyruvate carboxykinase and the glycolytic aldolase A gene expression by O2 in rat hepatocyte cultures. Involvement of hydrogen peroxide as mediator in the response to O2
    Thomas Kietzmann, Stefanie Freimann, Jutta Bratke · 1996 · FEBS Letters
  145. Role of p53 in antioxidant defense of HPV-positive cervical carcinoma cells following H2O2 exposure
    Boxiao Ding, Sung‐Gil Chi, Se Heon Kim, Suki Kang, Jaeho Cho, Dong Su Kim, Nam Hoon Cho · 2007 · Journal of Cell Science
  146. The Deficit in Low Molecular Weight Thiols as a Target for Antiageing Therapy
    Wulf Dröge, Ralf Kinscherf, Wulf Hildebrandt · 2006 · Current Drug Targets
  147. Airing Out an Antioxidant Role for the Tumor Suppressor p53
    Robert J. Tomko · 2006 · Molecular Interventions
  148. Pro-Oxidant Milieu Blunts Scissors: Insight into Tumor Progression, Drug Resistance, and Novel Druggable Targets
    Shazib Pervaiz · 2006 · Current Pharmaceutical Design
  149. Probing the presumed catalytic triad of a selenium-containing peroxidase by mutational analysis.
    Matilde Maiorino, Klaus-Dieter Aumann, R. Brigelius‐Flohé · 1998 · PubMed
  150. Redox Modulation of Cellular Metabolism Through Targeted Degradation of Signaling Proteins by the Proteasome
    Thomas C. Squier · 2006 · Antioxidants and Redox Signaling
  151. Protective Effect of Antioxidant Ebselen (PZ51) on the Cerebral Cortex of Stroke-Prone Spontaneously Hypertensive Rats
    Hui SUI, Wen Wang, Pei He WANG · 2005 · Hypertension Research
  152. Protein kinases and their therapeutic exploitation
    Louise Johnson · 2007 · Biochemical Society Transactions
  153. Contribution of glutamatergic signaling to nitrosative stress‐induced protein misfolding in normal brain aging and neurodegenerative diseases
    Tomohiro Nakamura, Zezong Gu, Stuart A. Lipton · 2007 · Aging Cell
  154. Antiapoptotic role of p38 mitogen activated protein kinase in Jurkat T cells and normal human T lymphocytes treated with 8-methoxypsoralen and ultraviolet-A radiation
    Alessandra Cappellini, Pier Luigi Tazzari, Irina Mantovani, Anna Maria Billi, Cristina Tassi, Francesca Ricci, Roberto Conte, Alberto Maria Martelli · 2005 · APOPTOSIS