Identification of Structural Elements in Nox1 and Nox4 Controlling Localization and Activity

The NOX Family of ROS-Generating NADPH Oxidases: Physiology and Pathophysiology

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Common Principles of Protein Translocation Across Membranes

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Subcellular localization of the b-cytochrome component of the human neutrophil microbicidal oxidase: translocation during activation.

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Nox proteins in signal transduction

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Identification of Renox, an NAD(P)H oxidase in kidney

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Functional analysis of Nox4 reveals unique characteristics compared to other NADPH oxidases

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NOX4 activity is determined by mRNA levels and reveals a unique pattern of ROS generation

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Distinct Subcellular Localizations of Nox1 and Nox4 in Vascular Smooth Muscle Cells

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Direct Interaction of the Novel Nox Proteins with p22phox Is Required for the Formation of a Functionally Active NADPH Oxidase

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SIGNAL-MEDIATED SORTING OF MEMBRANE PROTEINS BETWEEN THE ENDOPLASMIC RETICULUM AND THE GOLGI APPARATUS

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Two Novel Proteins Activate Superoxide Generation by the NADPH Oxidase NOX1

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NOX Enzymes in the Central Nervous System: From Signaling to Disease

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Regulation of ROS signal transduction by NADPH oxidase 4 localization

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Oxidative stress and glutathione in TGF-β-mediated fibrogenesis

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NADPH oxidase-4 mediates protection against chronic load-induced stress in mouse hearts by enhancing angiogenesis

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Assembly of the phagocyte NADPH oxidase

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Novel Human Homologues of p47 and p67 Participate in Activation of Superoxide-producing NADPH Oxidases

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Targeting and Regulation of Reactive Oxygen Species Generation by Nox Family NADPH Oxidases

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Nox4 Is Required for Maintenance of the Differentiated Vascular Smooth Muscle Cell Phenotype

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Ouabain-sensitive (Na+ + K+)-ATPase activity expressed in mouse L cells by transfection with DNA encoding the alpha-subunit of an avian sodium pump.

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Proteins Homologous to p47 and p67 Support Superoxide Production by NAD(P)H Oxidase 1 in Colon Epithelial Cells

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The superoxide‐producing NAD(P)H oxidase Nox4 in the nucleus of human vascular endothelial cells

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Regulation of NAD(P)H Oxidase by Associated Protein Disulfide Isomerase in Vascular Smooth Muscle Cells

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Hide and run. Arginine-based endoplasmic-reticulum-sorting motifs in the assembly of heteromultimeric membrane proteins

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Cytokine Activation of Nuclear Factor κB in Vascular Smooth Muscle Cells Requires Signaling Endosomes Containing Nox1 and ClC-3

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NOXO1, Regulation of Lipid Binding, Localization, and Activation of Nox1 by the Phox Homology (PX) Domain

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Receptor Activation of NADPH Oxidases

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Mapping sites of interaction of p47-phox and flavocytochrome b with random-sequence peptide phage display libraries.

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Association of gp91phox homolog Nox1 with anchorage-independent growth and MAP kinase-activation of transformed human keratinocytes

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Noxa1 is a central component of the smooth muscle NADPH oxidase in mice

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Functional association of nox1 with p22phox in vascular smooth muscle cells

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Determinants of UDP Glucuronosyltransferase Membrane Association and Residency in the Endoplasmic Reticulum

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The amino-terminal 29 amino acids of cytochrome P450 2C1 are sufficient for retention in the endoplasmic reticulum.

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The Cytoplasmic and N-terminal Transmembrane Domains of Cytochrome P450 Contain Independent Signals for Retention in the Endoplasmic Reticulum

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Crucial Role of Two Potential Cytosolic Regions of Nox2, 191TSSTKTIRRS200 and 484DESQANHFAVHHDEEKD500, on NADPH Oxidase Activation

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Mutagenesis of an Arginine- and Lysine-rich Domain in the gp91 Subunit of the Phagocyte NADPH-oxidase Flavocytochromeb 558

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NADPH oxidases are responsible for the failure of nitric oxide to inhibit migration of smooth muscle cells exposed to high glucose

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Synthetic Peptides Corresponding to Various Hydrophilic Regions of the Large Subunit of Cytochrome b558Inhibit Superoxide Generation in a Cell-Free System from Neutrophils

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Nox4 Is a Protective Reactive Oxygen Species Generating Vascular NADPH Oxidase

Schröder, K., Zhang, M., Benkhoff, S., Mieth, A., Pliquett, R., Kosowski, J., Kruse, C., Luedike, P., Michaelis, U. R., Weissmann, N., et al. (2012) · Circulation Research · doi:10.1161/circresaha.112.267054 · Cited by 622 · see citing works

Sources of Vascular Nitric Oxide and Reactive Oxygen Species and Their Regulation

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The NOX toolbox: validating the role of NADPH oxidases in physiology and disease

Altenhöfer, S., Kleikers, P. W. M., Radermacher, K. A., Scheurer, P., Rob Hermans, J. J., Schiffers, P., Ho, H., Wingler, K., & Schmidt, H. H. H. W. (2012) · Cellular and Molecular Life Sciences · doi:10.1007/s00018-012-1010-9 · Cited by 371 · see citing works

NADPH Oxidase 4 Promotes Endothelial Angiogenesis Through Endothelial Nitric Oxide Synthase Activation

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NADPH oxidases in oxidant production by microglia: activating receptors, pharmacology and association with disease

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Receptor Activation of NADPH Oxidases

Petry, A., Weitnauer, M., & Görlach, A. (2010) · Antioxidants & Redox Signaling · doi:10.1089/ars.2009.3026 · Cited by 162 · see citing works

Constitutive NADPH-Dependent Electron Transferase Activity of the Nox4 Dehydrogenase Domain

Nisimoto, Y., Jackson, H. M., Ogawa, H., Kawahara, T., & Lambeth, J. D. (2010) · Biochemistry · doi:10.1021/bi9022285 · Cited by 161 · see citing works

Endothelial NADPH oxidase 4 protects ApoE-/- mice from atherosclerotic lesions

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Novel Nox homologues in the vasculature: focusing on Nox4 and Nox5

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The contribution of Nox4 to NADPH oxidase activity in mouse vascular smooth muscle

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JAK/STAT Signaling Pathway Regulates Nox1 and Nox4-Based NADPH Oxidase in Human Aortic Smooth Muscle Cells

AdrianManea, IrinaTanase, L., MonicaRaicu, et al. (2010) · Arteriosclerosis Thrombosis and Vascular Biology

The Nox Family of NADPH Oxidases: Friend or Foe of the Vascular System?

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NADPH oxidase upregulates intermediate‐conductance Ca2+ ‐ activated K+ channels (KCa3.1) in coronary smooth muscle

Gole, H., & Bowles, D. K. (2011) · The FASEB Journal · doi:10.1096/fasebj.25.1_supplement.1026.16