Hydrogen sulfide and oxygen sensing in the cardiovascular system

Hydrogen sulphide and its therapeutic potential

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Two's company, three's a crowd: can H 2 S be the third endogenous gaseous transmitter?

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Hydrogen sulfide attenuates myocardial ischemia-reperfusion injury by preservation of mitochondrial function

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3-Mercaptopyruvate Sulfurtransferase Produces Hydrogen Sulfide and Bound Sulfane Sulfur in the Brain

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Whole tissue hydrogen sulfide concentrations are orders of magnitude lower than presently accepted values

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Three enzymatic activities catalyze the oxidation of sulfide to thiosulfate in mammalian and invertebrate mitochondria

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Sulfide as an environmental factor and toxicant: tolerance and adaptations in aquatic organisms

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H2S-induced vasorelaxation and underlying cellular and molecular mechanisms

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Massive release of hydrogen sulfide to the surface ocean and atmosphere during intervals of oceanic anoxia

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A direct microdetermination for sulfide

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Hypoxic pulmonary vasoconstriction

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Endogenous hydrogen sulfide regulation of myocardial injury induced by isoproterenol

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Evidence for the formation of a novel nitrosothiol from the gaseous mediators nitric oxide and hydrogen sulphide

Whiteman, M., Li, L., Kostetski, I., Chu, S. H., Siau, J. L., Bhatia, M., & Moore, P. K. (2006) · Biochemical and Biophysical Research Communications · doi:10.1016/j.bbrc.2006.02.154 · Cited by 377 · see citing works

Polarographic measurement of hydrogen sulfide production and consumption by mammalian tissues

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Remote Ischemic Preconditioning: A Novel Protective Method From Ischemia Reperfusion Injury—A Review

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Regulation of vascular nitric oxide in vitro and in vivo; a new role for endogenous hydrogen sulphide?

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H2S generated by heart in rat and its effects on cardiac function

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Reappraisal of H2S/sulfide concentration in vertebrate blood and its potential significance in ischemic preconditioning and vascular signaling

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Preconditioning and postconditioning: United at reperfusion

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Oxygen, the Janus gas; its effects on human placental development and function

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Hypoxia Tolerance in Mammals and Birds: From the Wilderness to the Clinic

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Hydrogen sulfide as an oxygen sensor/transducer in vertebrate hypoxic vasoconstriction and hypoxic vasodilation

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Association between cyclic GMP accumulation and acetylcholine-elicited relaxation of bovine intrapulmonary artery.

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Role of Hydrogen Sulfide in the Cardioprotection Caused by Ischemic Preconditioning in the Rat Heart and Cardiac Myocytes

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The role of hydrogen sulfide generation in the pathogenesis of hypertension in rats induced by inhibition of nitric oxide synthase

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Is hydrogen sulfide a circulating “gasotransmitter” in vertebrate blood?

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Hypoxia, Global Warming, and Terrestrial Late Permian Extinctions

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Hydrogen sulfide and its possible roles in myocardial ischemia in experimental rats

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Oxygen sensors in context

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Regulation of hypoxic pulmonary vasoconstriction: basic mechanisms

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Neuroepithelial oxygen chemoreceptors of the zebrafish gill

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Peripheral arterial chemoreceptors and the evolution of the carotid body

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Effects of hypoxia and other vasoactive agents on pulmonary and cerebral artery smooth muscle cells

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Endogenous hydrogen sulfide contributes to the cardioprotection by metabolic inhibition preconditioning in the rat ventricular myocytes

Pan, T., Feng, Z.-N., Lee, S. W., Moore, P. K., & Bian, J. (2005) · Journal of Molecular and Cellular Cardiology · doi:10.1016/j.yjmcc.2005.10.003 · Cited by 196 · see citing works

Direct inhibition of endothelial nitric oxide synthase by hydrogen sulfide: Contribution to dual modulation of vascular tension

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Cardioprotection induced by hydrogen sulfide preconditioning involves activation of ERK and PI3K/Akt pathways

Hu, Y., Chen, X., Pan, T., Neo, K. L., Lee, S. W., Khin, E. S. W., Moore, P. K., & Bian, J. (2007) · Pflügers Archiv - European Journal of Physiology · doi:10.1007/s00424-007-0321-4 · Cited by 175 · see citing works

Hydrogen sulfide mediates vasoactivity in an O2-dependent manner

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O2 sensing at the mammalian carotid body: why multiple O2 sensors and multiple transmitters?

Prabhakar, N. R. (2005) · Experimental Physiology · doi:10.1113/expphysiol.2005.031922 · Cited by 156 · see citing works

S-allylcysteine mediates cardioprotection in an acute myocardial infarction rat model via a hydrogen sulfide-mediated pathway

Chuah, S. C., Moore, P. K., & Zhu, Y. Z. (2007) · American Journal of Physiology-Heart and Circulatory Physiology · doi:10.1152/ajpheart.00853.2007 · Cited by 154 · see citing works

Responses of type I cells dissociated from the rabbit carotid body to hypoxia.

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Contractile and Vasorelaxant Effects of Hydrogen Sulfide and Its Biosynthesis in the Human Internal Mammary Artery

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Hydrogen sulfide as an oxygen sensor in trout gill chemoreceptors

Olson, K. R., Healy, M. J., Qin, Z., Skovgaard, N., Vulesevic, B., Duff, D. W., Whitfield, N. L., Yang, G., Wang, R., & Perry, S. F. (2008) · American Journal of Physiology-Regulatory, Integrative and Comparative Physiology · doi:10.1152/ajpregu.00807.2007 · Cited by 131 · see citing works

Metabolic integration during the evolutionary origin of mitochondria

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Pharmacological profile of a novel H2S-releasing aspirin

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The endogenous production of hydrogen sulphide in intrauterine tissues

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Hydrogen sulfide decreases adenosine triphosphate levels in aortic rings and leads to vasorelaxation via metabolic inhibition

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H2S preconditioning-induced PKC activation regulates intracellular calcium handling in rat cardiomyocytes

Pan, T., Neo, K. L., Hu, L., Yong, Q. C., & Bian, J. (2007) · American Journal of Physiology-Cell Physiology · doi:10.1152/ajpcell.00282.2007 · Cited by 114 · see citing works

Vasoconstrictive effect of hydrogen sulfide involves downregulation of cAMP in vascular smooth muscle cells

Lim, J. J., Liu, Y.-H., Khin, E. S. W., & Bian, J. (2008) · American Journal of Physiology-Cell Physiology · doi:10.1152/ajpcell.00195.2008 · Cited by 107 · see citing works

Regulation of oxygen sensing by ion channels

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Exogenous Hydrogen Sulfide Inhibits Superoxide Formation, NOX-1 Expression and Rac1 Activity in Human Vascular Smooth Muscle Cells

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Hydrogen sulphide regulates intracellular pH in vascular smooth muscle cells

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S-propargyl-cysteine Protects Both Adult Rat Hearts and Neonatal Cardiomyocytes From Ischemia/Hypoxia Injury: The Contribution of the Hydrogen Sulfide-Mediated Pathway

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Acute oxygen sensing: diverse but convergent mechanisms in airway and arterial chemoreceptors

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Hydrogen Sulfide Inhibits Human BKCa Channels

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Negative regulation of β-adrenergic function by hydrogen sulphide in the rat hearts

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Hydrogen sulfide and oxygen sensing: implications in cardiorespiratory control

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Hydrogen sulfide potentiates interleukin-1β-induced nitric oxide production via enhancement of extracellular signal-regulated kinase activation in rat vascular smooth muscle cells

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Detection of exhaled hydrogen sulphide gas in rats exposed to intravenous sodium sulphide

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Postconditioning: a mechanical maneuver that triggers biological and molecular cardioprotective responses to reperfusion

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Airway Chemotransduction: From Oxygen Sensor to Cellular Effector

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Mitochondrial oxygen tension within the heart

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Point:Counterpoint: Hypoxic pulmonary vasoconstriction is/is not mediated by increased production of reactive oxygen species

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Enzymatic hydrogen sulfide production in marine invertebrate tissues

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Hydrogen sulfide mediates hypoxia-induced relaxation of trout urinary bladder smooth muscle

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Cyclooxygenase-2 mediates the delayed cardioprotection induced by hydrogen sulfide preconditioning in isolated rat cardiomyocytes

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Oxygen dependency of hydrogen sulfide-mediated vasoconstriction in cyclostome aortas

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All in the timing: A comparison between the cardioprotection induced by H2S preconditioning and post-infarction treatment

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Potential Applications of Hydrogen Sulfide-Induced Suspended Animation

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Hypoxic vasoconstriction of cyclostome systemic vessels: the antecedent of hypoxic pulmonary vasoconstriction?

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AMP‐activated protein kinase underpins hypoxic pulmonary vasoconstriction and carotid body excitation by hypoxia in mammals

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Coping with cyclic oxygen availability: evolutionary aspects

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Oxygen Sensing in Neuroepithelial and Adrenal Chromaffin Cells

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Hypoxic vasorelaxation: Ca2+-dependent and Ca2+-independent mechanisms

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Mechanisms of oxygen sensing: a key to therapy of pulmonary hypertension and patent ductus arteriosus

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Hydrogen Sulfide Production and Metabolism in Mammalian Tissues

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Oxygen-sensing through production of hydrogen sulphide in peripheral chemoreceptors

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Physiological Implications of Hydrogen Sulfide: A Whiff Exploration That Blossomed

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Physiological roles of hydrogen sulfide in mammalian cells, tissues, and organs

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Assessing bioenergetic function in response to oxidative stress by metabolic profiling

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Regulation of mitochondrial bioenergetic function by hydrogen sulfide. Part I . Biochemical and physiological mechanisms

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Hydrogen Sulfide in Biochemistry and Medicine

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Chemical foundations of hydrogen sulfide biology

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Biology and therapeutic potential of hydrogen sulfide and hydrogen sulfide-releasing chimeras

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Molecular Strategies for Targeting Antioxidants to Mitochondria: Therapeutic Implications

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Hydrogen Sulfide: The Third Gasotransmitter in Biology and Medicine

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Organization of the Human Mitochondrial Hydrogen Sulfide Oxidation Pathway

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Hydrogen Sulfide in the Mammalian Cardiovascular System

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Structure and Kinetic Analysis of H2S Production by Human Mercaptopyruvate Sulfurtransferase

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Mitochondria and Sulfide: A Very Old Story of Poisoning, Feeding, and Signaling?

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A Practical Look at the Chemistry and Biology of Hydrogen Sulfide

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Electrochemical hydrogen sulfide biosensors

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Homocysteine and the pathogenesis of atherosclerosis

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The therapeutic potential of hydrogen sulfide: separating hype from hope

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Passive loss of hydrogen sulfide in biological experiments

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