The DOI matches its Crossref record; 125 of the 125 references it cites were found in a registry or an index.
Alpha-2 Adrenergic Receptor Agonists for the Treatment of Attention-Deficit/Hyperactivity Disorder: Emerging Concepts from New Data
Abstract
Recent developments in the field of neuroscience have illuminated the understanding of the neural circuits impaired in attention-deficit/hyperactivity disorder (ADHD) and the mechanism of action of treatments used to treat this condition. There is an exciting confluence between emerging studies in basic neurobiology and the genetic, neuroimaging, and neuropsychological analyses of ADHD. The following provides a brief review of this field, explaining how compounds like guanfacine and the traditional stimulant medications can reduce the core symptoms of ADHD by optimizing the neurochemical environment in the prefrontal cortex (PFC). Knowledge of these basic mechanisms may inform our medication choices and facilitate treatment of ADHD and related disorders.
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Cites
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Cited by
Neural mechanisms of selective visual attention.
Moore, T., & Zirnsak, M. (2017) · Annual Review of Psychology · doi:10.1146/annurev-psych-122414-033400 · Cited by 471
Sallee, F. R., Mcgough, J., Wigal, T., Donahue, J., Lyne, A., & Biederman, J. (2009) · Journal of the American Academy of Child & Adolescent Psychiatry · doi:10.1097/chi.0b013e318191769e · Cited by 391
Arnsten, A. F. T. (2009) · CNS Drugs · doi:10.2165/00023210-200923000-00005 · Cited by 371
Self-citationSpencer, T. J., Greenbaum, M., Ginsberg, L. D., & Murphy, W. R. (2009) · Journal of Child and Adolescent Psychopharmacology · doi:10.1089/cap.2008.0152 · Cited by 257
Hannestad, J., Gallezot, J.-D., Planeta-Wilson, B., Lin, S.-F., Williams, W. A., van Dyck, C. H., Malison, R. T., Carson, R. E., & Ding, Y.-S. (2010) · Biological Psychiatry · doi:10.1016/j.biopsych.2010.06.017 · Cited by 236
Metadata
- Authors
- Arnsten, A. F., Scahill, L., & Findling, R. L.
- Venue
- Journal of Child and Adolescent Psychopharmacology
- Publisher
- SAGE Publications
- Published
- 2007-08
- Volume
- 17
- Issue
- 4
- Pages
- 393-406
- ISSN
- 1044-5463 (ISSN-L)
- 1557-8992
- OpenAlex
- W1972551153
- Cited by
- 307
- References
- 125
- FWCI
- 5.64
- Type
- journal article
- Language
- en
- Open access
- closed
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- CoChat. (2026). Citation check: Alpha-2 Adrenergic Receptor Agonists for the Treatment of Attention-Deficit/Hyperactivity Disorder: Emerging Concepts from New Data. https://app.cochat.ai/papers/10.1089/cap.2006.0098
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- Arnsten, A. F., Scahill, L., & Findling, R. L. (2007). Alpha-2 Adrenergic Receptor Agonists for the Treatment of Attention-Deficit/Hyperactivity Disorder: Emerging Concepts from New Data. Journal of Child and Adolescent Psychopharmacology. https://doi.org/10.1089/cap.2006.0098
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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