The DOI matches its Crossref record; 70 of the 71 references it cites were found in a registry or an index.
The Neurobiology of Impulsive Aggression
Open accessAbstract
This selective review provides a model of the neurobiology of impulsive aggression from a cognitive neuroscience perspective. It is argued that prototypical cases of impulsive aggression, those associated with anger, involve the recruitment of the acute threat response system structures; that is, the amygdala, hypothalamus, and periaqueductal gray. It is argued that whether the recruitment of these structures results in impulsive aggression or not reflects the functional roles of ventromedial frontal cortex and dorsomedial frontal and anterior insula cortex in response selection. It is also argued that impulsive aggression may occur because of impaired decision making. The aggression may not be accompanied by anger, but it will reflect disrupted evaluation of the rewards/benefits of the action.
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“In addition, the insula has also been reported to mediate the states of anger, aggression, and social emotion [62,[67][68][69].”
From The Insular Cortex: An Interface Between Sensation, Emotion and Cognition (2024) · cites this paper as [68]
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Cites
Affective Neuroscience: The Foundations of Human and Animal Emotions
Panksepp, J. (1998) · doi:10.1093/oso/9780195096736.001.0001 · Cited by 4,428
Delay of gratification in children.
Mischel, W., Shoda, Y., & Rodriguez, M. L. (1989) · Science · doi:10.1126/science.2658056 · Cited by 3,397
The neural basis of economic decision-making in the Ultimatum Game.
Sanfey, A. G., Rilling, J. K., Aronson, J. A., Nystrom, L. E., & Cohen, J. D. (2003) · Science · doi:10.1126/science.1082976 · Cited by 3,375
Emotional processing in anterior cingulate and medial prefrontal cortex
Etkin, A., Egner, T., & Kalisch, R. (2011) · Trends in Cognitive Sciences · doi:10.1016/j.tics.2010.11.004 · Cited by 3,059 · cited 1×
“The dominant view is that the vmPFC inhibits (‘‘puts the brakes on’’) the aggressive responses mediated by the amygdala, hypothalamus, and PAG ( Nelson and Trainor 2007; Schiller and Delgado 2010; Diekhof et al. 2011; Etkin et al. 2011).”
BackgroundSelf-Control in Decision-Making Involves Modulation of the vmPFC Valuation System
Hare, T. A., Camerer, C. F., & Rangel, A. (2009) · Science · doi:10.1126/science.1168450 · Cited by 1,928
Cognitive Reappraisal of Emotion: A Meta-Analysis of Human Neuroimaging Studies
Buhle, J. T., Silvers, J. A., Wager, T. D., Lopez, R., Onyemekwu, C., Kober, H., Weber, J., & Ochsner, K. N. (2014) · Cerebral Cortex · doi:10.1093/cercor/bht154 · Cited by 1,896 · cited 1×
“For example, the fMRI literature indicates that the vmPFC is not involved in emotional regulation (Buhle et al. 2014).”
BackgroundAmygdala, medial prefrontal cortex, and hippocampal function in PTSD
SHIN, L. M., RAUCH, S. L., & PITMAN, R. K. (2006) · Annals of the New York Academy of Sciences · doi:10.1196/annals.1364.007 · Cited by 1,203
Neural mechanisms of aggression
Nelson, R. J., & Trainor, B. C. (2007) · Nature reviews. Neuroscience · doi:10.1038/nrn2174 · Cited by 1,046
Medial prefrontal cortex as an action-outcome predictor
Alexander, W. H., & Brown, J. W. (2011) · Nature Neuroscience · doi:10.1038/nn.2921 · Cited by 1,000
Dodge, K. A., Lochman, J. E., Harnish, J. D., Bates, J. E., & al, E. (1997) · Journal of Abnormal Psychology · doi:10.1037//0021-843x.106.1.37 · Cited by 975
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Items 201–235 of 235
Guillén-Corchado, D. (2024) · Acta Psychologica · doi:10.1016/j.actpsy.2024.104408
Pilechev, D., Mikadze, Y. V., Vandysh-Bubko, V. V., & Владимировна, Г. М. (2024) · Psikhiatriya · doi:10.30629/2618-6667-2024-22-3-73-90
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Oppositionelle, aggressive und dissoziale Verhaltensstörungen in Kindheit und Jugend
Görtz‐Dorten, A., Döpfner, M., & Banaschewski, T. (2024) · Springer Reference Medizin · doi:10.1007/978-3-662-66744-6_125
Anandamide in personality disorders
Kolla, N. J., & Pol, M. D. (2024) · Elsevier eBooks · doi:10.1016/b978-0-443-19081-0.00012-3
Romero‐Martínez, Á., Robles, M. B., Cerdá-Alberich, L., Aparici, F., Martí‐Bonmatí, L., Sarrate‐Costa, C., Lila, M., & Moya‐Albiol, L. (2024) · Journal of Psychiatric Research · doi:10.1016/j.jpsychires.2024.09.019
Seidenbecher, S., Kaufmann, J., Schöne, M., Dobrowolny, H., Schiltz, K., Frodl, T., Steiner, J. H., Bogerts, B., & Nickl‐Jockschat, T. (2024) · NeuroImage Clinical · doi:10.1016/j.nicl.2024.103712
Dubol, M., Gröndal, M., Schmidt, F., Fisher, P. M., Frøkjær, V. G., Eriksson, E., Poromaa, I. S., & Comasco, E. (2025) · Research Square · doi:10.21203/rs.3.rs-6224514/v1
Wingen, M. V. S., Andrade, F. R. T., Dalzochio, N. B., Thalheimer, G., Machado, A. B. C., Trivilin, T., & de Almeida, R. M. M. (2025) · Journal of Substance Use · doi:10.1080/14659891.2025.2494528
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Michalska, K. J., & Firat, R. B. (2025) · Handbooks of sociology and social research · doi:10.1007/978-3-031-95615-7_25
Palumbo, S., Grassi, G., Mariotti, V., & Pellegrini, S. (2025) · Aggression and Violent Behavior · doi:10.1016/j.avb.2025.102096
Kausar, N., Farwa, U.-E., Khalid, R., & Ilyas, S. (2025) · journal of social sciences review · doi:10.62843/jssr.v5i4.608
Decrop, R., Rodgers, E. L., Frick, P. J., Steinberg, L. D., & Cauffman, E. E. (2026) · Assessment · doi:10.1177/10731911251407472
Chen, P. (2025) · Journal of management and social development. · doi:10.62517/jmsd.202512605
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Chandarana, M. (2026) · Cambridge University Press eBooks · doi:10.1017/9781009335874.002
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Zhang, X., Li, S., Si, Y., & Sun, L. (2026) · Journal of Adolescence · doi:10.1002/jad.70167
Cima, M., Oosterling, M., Loheide‐Niesmann, L., Meulenbeek, K., Spagnuolo, F., Tonnaer, F., Frankenberger, L., Riem, M. M. E., & Thijssen, S. (2026) · Aggression and Violent Behavior · doi:10.1016/j.avb.2026.102158
Awathale, S. N., Chaudhari, A., Pardeshi, G. N., Popali, C., Goyal, S. N., & Nakhate, K. T. (2026) · Neuropeptides · doi:10.1016/j.npep.2026.102620
Distorsiones cognitivas y conducta antisocial delictiva: una revisión sistemática
Escallón, M. G., & Díaz-Granados, E. T. A. (2026) · Justicia · doi:10.17081/just.31.49.8792
Problems with Anger and Aggression in Individuals Living with Serious Mental Illness
McKeegan, G. F. (2026) · Evidence-based practices in behavioral health · doi:10.1007/978-3-032-18372-9_11
Norouzi, E., Hossieni, S. A., Zandi, K., & Ahmadi, A. (2026) · Pastoral Care in Education · doi:10.1080/02643944.2026.2696461
Ahmad, D. F. (2026) · Integrative Psychological and Behavioral Science · doi:10.1007/s12124-026-10015-2
Kero, D., Marlies, D., & Affenzeller, N. (2026) · Frontiers in Veterinary Science · doi:10.3389/fvets.2026.1869578
Rodent models of aggression: from mechanisms to clinical translation
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Liu, L. (2026) · American Journal of Criminal Justice · doi:10.1007/s12103-026-09942-y
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Nejati, V., & Khorrami, A. S. (2026) · Progress in brain research · doi:10.1016/bs.pbr.2026.08.004
Simpson, P. L., Stephenson, F., Morgan, P. F., Akpanekpo, E. I., Jones, J., Schofield, P. W., Knight, L. G., & Butler, T. G. (2026) · International Journal of Offender Therapy and Comparative Criminology · doi:10.1177/0306624x261490592
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Konrad, K., Reindl, V., Banaschewski, T., Holz, N. E., Chiocchetti, A. G., Ecker, C., Tost, H., Meyer‐Lindenberg, A., Habel, U., & Freitag, C. M. (2026) · Der Nervenarzt · doi:10.1007/s00115-026-02028-4
Metadata
- Authors
- Blair, R. J. R.
- Affiliations
- National Institutes of Health
- Venue
- Journal of Child and Adolescent Psychopharmacology
- Publisher
- SAGE Publications
- Published
- 2016-02
- Volume
- 26
- Issue
- 1
- Pages
- 4-9
- ISSN
- 1044-5463 (ISSN-L)
- 1557-8992
- PMC
- PMC4779272
- OpenAlex
- W2245990605
- Cited by
- 235
- References
- 71
- Citations by year
- 2026: 23 · 2025: 25 · 2024: 29 · 2023: 31 · 2022: 20 · 2021: 36 · 2020: 28 · 2019: 15 · 2018: 13 · 2017: 9 · 2016: 5
- FWCI
- 5.41
- Type
- journal article
- Language
- en
- Open access
- green
- www.ncbi.nlm.nih.gov
- Locations
- Journal of Child and Adolescent Psychopharmacology (publishedVersion)
- Europe PMC (PubMed Central) (publishedVersion)
- PubMed Central (publishedVersion)
- PubMed (publishedVersion)
- Funders
- National Institutes of Health
- National Institute of Mental Health (1-ZIA-MH002860, 1‑ZIA‑MH002860‑08, ZIAMH002860)
- Topics
- Life Sciences › Neuroscience › Cognitive Neuroscience › Neural and Behavioral Psychology Studies
- Social Sciences › Psychology › Clinical Psychology › Psychopathy, Forensic Psychiatry, Sexual Offending
- Social Sciences › Psychology › Social Psychology › Bullying, Victimization, and Aggression
- Keywords
- impulsive aggression, neurobiology of aggression, amygdala, hypothalamus, periaqueductal gray, ventromedial prefrontal cortex, dorsomedial prefrontal cortex, anterior insula, response selection, decision-making, reward evaluation, anger
- MeSH terms
- Aggression, Brain, Humans, Impulsive Behavior, Neurobiology
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