The DOI matches its Crossref record; 19 of the 19 references it cites were found in a registry or an index.
Ancestral Inference from Samples of DNA Sequences with Recombination
Abstract
The sampling distribution of a collection of DNA sequences is studied under a model where recombination can occur in the ancestry of the sequences. The infinitely-many-sites model of mutation is assumed where there may only be one mutation at a given site. Ancestral inference procedures are discussed for: estimating recombination and mutation rates; estimating the times to the most recent common ancestors along the sequences; estimating ages of mutations; and estimating the number of recombination events in the ancestry of the sample. Inferences are made conditional on the configuration of the pattern of mutations at sites in observed sample sequences. A computational algorithm based on a Markov chain simulation is developed, implemented, and illustrated with examples for these inference procedures. This algorithm is very computationally intensive.
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Cites
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Self-citationThe coalescent process in models with selection and recombination.
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Cited by
A Simple and Robust Statistical Test for Detecting the Presence of Recombination
Bruen, T. C., Philippe, H., & Bryant, D. (2006) · Genetics · doi:10.1534/genetics.105.048975 · Cited by 1,382
Drummond, A. J., Nicholls, G. K., Rodrigo, A. G., & Solomon, W. (2002) · Genetics · doi:10.1093/genetics/161.3.1307 · Cited by 1,059
Genealogical trees, coalescent theory and the analysis of genetic polymorphisms
Rosenberg, N. A., & Nordborg, M. (2002) · Nature Reviews Genetics · doi:10.1038/nrg795 · Cited by 750
A Coalescent-Based Method for Detecting and Estimating Recombination From Gene Sequences
McVean, G., Awadalla, P., & Fearnhead, P. (2002) · Genetics · doi:10.1093/genetics/160.3.1231 · Cited by 708
Haplotype blocks and linkage disequilibrium in the human genome
Wall, J. D., & Pritchard, J. K. (2003) · Nature Reviews Genetics · doi:10.1038/nrg1123 · Cited by 642
Metadata
- Authors
- GRIFFITHS, R. C., & MARJORAM, P.
- Venue
- Journal of Computational Biology
- Publisher
- SAGE Publications
- Published
- 1996-01
- Volume
- 3
- Issue
- 4
- Pages
- 479-502
- ISSN
- 1066-5277 (ISSN-L)
- 1557-8666
- OpenAlex
- W1979900996
- Cited by
- 403
- References
- 19
- FWCI
- 2.60
- Type
- journal article
- Language
- en
- Open access
- closed
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
