The DOI matches its Crossref record; 8 of the 8 references it cites were found in a registry or an index.
Hypoglycemia Prevention and User Acceptance of an Insulin Pump System with Predictive Low Glucose Management
Open accessAbstract
BACKGROUND: The MiniMed 640G sensor-augmented insulin pump system (Medtronic, Inc., Northridge, CA) can automatically suspend insulin delivery in advance of predicted hypoglycemia and restart it upon recovery. The aims of this analysis were to determine the rate at which predicted hypoglycemia was avoided with this strategy, as well as to assess user acceptance of the system and its insulin management features. SUBJECTS AND METHODS: Forty subjects with type 1 diabetes used the system for 4 weeks. We retrospectively evaluated performance of the system, using downloaded pump and sensor data, and evaluated user acceptance via questionnaires. RESULTS: There were 2,322 suspend before low events (2.1 per subject-day). The mean (± SD) duration of pump suspension events was 56.4 ± 9.6 min, and the mean subsequent sensor glucose (SG) nadir was 71.8 ± 5.2 mg/dL. SG values following 1,930 (83.1%) of the predictive suspensions did not reach the preset low limit. Nadir SG values of ≤50 and ≤60 mg/dL were seen in 207 (8.9%) and 356 (15.3%) of the predictive suspensions, respectively. Blood glucose (BG) and SG values before and during the study were comparable (P > 0.05). The mean absolute relative difference between paired SG and BG values was 10.9 ± 13.8%. Subjects felt confident using the system, agreed that it helped protect them from hypoglycemia, and wished to continue using it. CONCLUSIONS: Automatic insulin pump suspension as implemented in the MiniMed 640G system can help patients avoid hypoglycemia, without significantly increasing hyperglycemia.
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“Numerous studies have demonstrated significant clinical benefits of CGM use in people with diabetes regardless of insulin delivery method (1-15).”
From Clinical Targets for Continuous Glucose Monitoring Data Interpretation: Recommendations From the International Consensus on Time in Range (2019) · cites this paper as [10]
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Cites
Threshold-based insulin-pump interruption for reduction of hypoglycemia
Bergenstal, R. M., Klonoff, D. C., Garg, S. K., Bode, B. W., Meredith, M., Slover, R. H., Ahmann, A. J., Welsh, J. B., Lee, S. W., & Kaufman, F. R. (2013) · New England Journal of Medicine · doi:10.1056/nejmoa1303576 · Cited by 652
Self-citationLy, T. T., Nicholas, J. A., Retterath, A., Lim, E. M., Davis, E. A., & Jones, T. W. (2013) · JAMA · doi:10.1001/jama.2013.277818 · Cited by 411
Insulin Pump Therapy With Automated Insulin Suspension in Response to Hypoglycemia
Choudhary, P., Shin, J., Wang, Y., Evans, M. L., Hammond, P. J., Kerr, D., Shaw, J. A. M., Pickup, J. C., & Amiel, S. A. (2011) · Diabetes Care · doi:10.2337/dc10-2411 · Cited by 175
Self-citationPrevention of Nocturnal Hypoglycemia Using Predictive Alarm Algorithms and Insulin Pump Suspension
Buckingham, B., Chase, H. P., Dassau, E., Cobry, E., Clinton, P., Gage, V., Caswell, K., Wilkinson, J., Cameron, F., Lee, H., et al. (2010) · Diabetes Care · doi:10.2337/dc09-2303 · Cited by 169
A Randomized Trial of a Home System to Reduce Nocturnal Hypoglycemia in Type 1 Diabetes
Maahs, D. M., Calhoun, P. M., Buckingham, B. A., Chase, H. P., HRAMIAK, I. M., Lum, J. W., Cameron, F., Bequette, B. W., Aye, T., Paul, T., et al. (2014) · Diabetes Care · doi:10.2337/dc13-2159 · Cited by 163
Danne, T., Tsioli, C., Kordonouri, O., Bläsig, S., Remus, K., Roy, A., Keenan, D. B., Lee, S. W., & KAUFMAN, F. R. (2014) · Diabetes Technology & Therapeutics · doi:10.1089/dia.2013.0327 · Cited by 91
Beck, R. W., Raghinaru, D., Wadwa, R. P., Chase, H. P., Maahs, D. M., Buckingham, B. A., & for the In Home Closed Loop Study Group (2014) · Diabetes Care · doi:10.2337/dc13-2775 · Cited by 44
Giannopoulou, E. Z., Puff, R., Beyerlein, A., von Luettichau, I., Boerschmann, H., Schatz, D., Atkinson, M. A., Haller, M. J., Egger, D., Burdach, S. E. G., et al. (2013) · Pediatric Diabetes · doi:10.1111/pedi.12072 · Cited by 36
Research works printed but not linked: 3
- De Bock MI, , Dart J, , George CE, , Abraham M, , Cooper M, , Paramalingam N, , Keenan B, , Spital G, , Roy A, , Davis EA, , Jones TW: Performance of a predictive insulin pump suspension algorithm for prevention of overnight hypoglycaemia [abstract]. Diabetes, 2014; 63:A240–A241.
- Veeze H, , Rasmussen LG, , Agrawal P, , Zhong A, , Arietta A, , Kooi N, , Liabat S, , Shah R, , Kaufman F: Real-life performance evaluation of the New Generation Enlite™ glucose sensor in patients with diabetes mellitus. Pediatr Diabetes, 2014; 15:100.
- Abraham M, , Davey R, , Paramalingam N, , Keenan B, , Ambler G, , Fairchild J, , Cameron F, , King B, , Jones T, , Davis E: Prevention of hypoglycaemia with predictive low glucose management system: comparison of hypoglycaemia induction with exercise and subcutaneous bolus [abstract]. Diabetes Technol Ther, 2014; 16:A43.
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Sorted by citations
Battelino, T., Danne, T., Bergenstal, R. M., Amiel, S. A., Beck, R., Biester, T., Bosi, E., Buckingham, B. A., Cefalu, W. T., Close, K. L., et al. (2019) · Diabetes Care · doi:10.2337/dci19-0028 · Cited by 4,237
Bolinder, J., Antuna, R., Geelhoed-Duijvestijn, P., Kröger, J., & Weitgasser, R. (2016) · The Lancet · doi:10.1016/s0140-6736(16)31535-5 · Cited by 893
Safety of a hybrid closed-loop insulin delivery system in patients with type 1 diabetes
Bergenstal, R. M., Garg, S., Weinzimer, S. A., Buckingham, B. A., Bode, B. W., Tamborlane, W. V., & Kaufman, F. R. (2016) · JAMA · doi:10.1001/jama.2016.11708 · Cited by 644
Garg, S. K., Weinzimer, S. A., Tamborlane, W. V., Buckingham, B. A., Bode, B. W., Bailey, T. S., Brazg, R. L., Ilany, J., Slover, R. H., Anderson, S. M., et al. (2017) · Diabetes Technology & Therapeutics · doi:10.1089/dia.2016.0421 · Cited by 585
Self-citationCappon, G., Vettoretti, M., Sparacino, G., & Facchinetti, A. (2019) · Diabetes & Metabolism Journal · doi:10.4093/dmj.2019.0121 · Cited by 477
Metadata
- Authors
- Choudhary, P., Olsen, B. S., Conget, I., Welsh, J. B., Vorrink, L., & Shin, J. J.
- Affiliations
- King's College London (GB)
- Herlev Hospital (DK)
- Clinic and University Hospital
- Medtronic (Switzerland) (CH)
- Medtronic (United States) (US)
- Corresponding author
- Choudhary, Pratik
- Venue
- Diabetes Technology & Therapeutics
- Publisher
- SAGE Publications
- Published
- 2016-05
- Volume
- 18
- Issue
- 5
- Pages
- 288-291
- ISSN
- 1520-9156 (ISSN-L)
- 1557-8593
- PMC
- PMC4870649
- OpenAlex
- W2330613462
- Cited by
- 118
- References
- 8
- Citations by year
- 2026: 1 · 2025: 2 · 2024: 3 · 2023: 3 · 2022: 9 · 2021: 7 · 2020: 11 · 2019: 18 · 2018: 23 · 2017: 31 · 2016: 10
- FWCI
- 27.43
- Type
- journal article
- Language
- en
- Open access
- hybrid
- doi.org
- Licence
- Locations
- Diabetes Technology & Therapeutics (publishedVersion, cc-by-nc)
- Europe PMC (PubMed Central) (publishedVersion, cc-by-nc)
- PubMed Central (publishedVersion, cc-by-nc)
- PubMed (publishedVersion)
- Research Portal (King's College London) (publishedVersion, cc-by-nc)
- Topics
- Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Diabetes Management and Research
- Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Diabetes Management and Education
- Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Diabetes Treatment and Management
- Keywords
- hypoglycemia prevention, type 1 diabetes, sensor-augmented pump, user acceptance, continuous glucose monitoring, hyperglycemia
- MeSH terms
- Adult, Blood Glucose, Child, Humans, Hypoglycemia, Hypoglycemic Agents, Insulin, Insulin Infusion Systems, Retrospective Studies
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