The DOI matches its Crossref record; 6 of the 6 references it cites were found in a registry or an index.
Harnessing and Modulating Inflammation in Strategies for Bone Regeneration
Open accessAbstract
Inflammation is an immediate response that plays a critical role in healing after fracture or injury to bone. However, in certain clinical contexts, such as in inflammatory diseases or in response to the implantation of a biomedical device, the inflammatory response may become chronic and result in destructive catabolic effects on the bone tissue. Since our previous review 3 years ago, which identified inflammatory signals critical for bone regeneration and described the inhibitory effects of anti-inflammatory agents on bone healing, a multitude of studies have been published exploring various aspects of this emerging field. In this review, we distinguish between regenerative and damaging inflammatory processes in bone, update our discussion of the effects of anti-inflammatory agents on bone healing, summarize recent in vitro and in vivo studies demonstrating how inflammation can be modulated to stimulate bone regeneration, and identify key future directions in the field.
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Cites
T-Cell mediated regulation of osteoclastogenesis by signalling cross-talk between RANKL and IFN-γ.
Takayanagi, H., Ogasawara, K., Hida, S., Chiba, T., Murata, S., Sato, K., Takaoka, A., Yokochi, T., Oda, H., Tanaka, K., et al. (2000) · Nature · doi:10.1038/35046102 · Cited by 1,358
TRANCE/RANKL knockout mice are protected from bone erosion in a serum transfer model of arthritis.
Pettit, A. R., Ji, H., von Stechow, D., Müller, R., Goldring, S. R., Choi, Y., Benoist, C., & Gravallese, E. M. (2001) · The American Journal of Pathology · doi:10.1016/s0002-9440(10)63016-7 · Cited by 807
Kon, T., Cho, T.-J., Aizawa, T., Yamazaki, M., Nooh, N., Graves, D., Gerstenfeld, L. C., & Einhorn, T. A. (2001) · Journal of Bone and Mineral Research · doi:10.1359/jbmr.2001.16.6.1004 · Cited by 552
Fracture healing is accelerated in the absence of the adaptive immune system
Toben, D., Schroeder, I., El Khassawna, T., Mehta, M., Hoffmann, J.-E., Frisch, J.-T., Schell, H., Lienau, J., Serra, A., Radbruch, A., et al. (2011) · Journal of Bone and Mineral Research · doi:10.1002/jbmr.185 · Cited by 236
Tanaka, M., Sakai, A., Uchida, S., Tanaka, S., Nagashima, M., Katayama, T., Yamaguchi, K., & Nakamura, T. (2004) · Bone · doi:10.1016/j.bone.2004.01.002 · Cited by 107
Aspenberg, P. (2005) · Acta Orthopaedica · doi:10.1080/17453670510045318 · Cited by 97
Cited by
Bone Tissue Engineering: Recent Advances and Challenges
Amini, A. R., Laurencin, C. T., & Nukavarapu, S. P. (2012) · Critical Reviews in Biomedical Engineering · doi:10.1615/critrevbiomedeng.v40.i5.10 · Cited by 2,336
Inflammation, fracture and bone repair
Loi, F., Córdova, L. A., Pajarinen, J., Lin, T.-H., Yao, Z., & Goodman, S. B. (2016) · Bone · doi:10.1016/j.bone.2016.02.020 · Cited by 1,293
3D Printing of Scaffolds for Tissue Regeneration Applications
Do, A., Khorsand, B., Geary, S. M., & Salem, A. K. (2015) · Advanced Healthcare Materials · doi:10.1002/adhm.201500168 · Cited by 949
Strategies for controlled delivery of growth factors and cells for bone regeneration
Vo, T. N., Kasper, F. K., & Mikos, A. G. (2012) · Advanced Drug Delivery Reviews · doi:10.1016/j.addr.2012.01.016 · Cited by 666
Self-citationEvaluation of bone regeneration using the rat critical size calvarial defect
Spicer, P. P., Kretlow, J. D., Young, S., Jansen, J. A., Kasper, F. K., & Mikos, A. G. (2012) · Nature Protocols · doi:10.1038/nprot.2012.113 · Cited by 664
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Metadata
- Authors
- Mountziaris, P. M., Spicer, P. P., Kasper, F. K., & Mikos, A. G.
- Venue
- Tissue Engineering Part B: Reviews
- Publisher
- SAGE Publications
- Published
- 2011-12
- Volume
- 17
- Issue
- 6
- Pages
- 393-402
- ISSN
- 1937-3368 (ISSN-L)
- 1937-3376
- OpenAlex
- W2068680564
- Cited by
- 217
- References
- 6
- FWCI
- 6.11
- Type
- journal article
- Language
- en
- Open access
- green
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- Mountziaris, P. M., Spicer, P. P., Kasper, F. K., & Mikos, A. G. (2011). Harnessing and Modulating Inflammation in Strategies for Bone Regeneration. Tissue Engineering Part B: Reviews. https://doi.org/10.1089/ten.teb.2011.0182
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
