The DOI matches its Crossref record; 253 of the 253 references it cites were found in a registry or an index.
Strategies for controlled delivery of growth factors and cells for bone regeneration
Open accessAbstract
The controlled delivery of growth factors and cells within biomaterial carriers can enhance and accelerate functional bone formation. The carrier system can be designed with preprogrammed release kinetics to deliver bioactive molecules in a localized, spatiotemporal manner most similar to the natural wound healing process. The carrier can also act as an extracellular matrix-mimicking substrate for promoting osteoprogenitor cellular infiltration and proliferation for integrative tissue repair. This review discusses the role of various regenerative factors involved in bone healing and their appropriate combinations with different delivery systems for augmenting bone regeneration. The general requirements of protein, cell and gene therapy are described, with elaboration on how the selection of materials, configurations and processing affects growth factor and cell delivery and regenerative efficacy in both in vitro and in vivo applications for bone tissue engineering.
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1 retracted
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Nanomaterials and bone regeneration
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Bone tissue engineering via growth factor delivery: from scaffolds to complex matrices
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Poly (lactic acid)-based biomaterials for orthopaedic regenerative engineering
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The application of hyaluronic acid in bone regeneration
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Metadata
- Authors
- Vo, T. N., Kasper, F. K., & Mikos, A. G.
- Venue
- Advanced Drug Delivery Reviews
- Publisher
- Elsevier BV
- Published
- 2012-09
- Volume
- 64
- Issue
- 12
- Pages
- 1292-1309
- ISSN
- 0169-409X (ISSN-L)
- OpenAlex
- W1981701289
- Cited by
- 666
- References
- 253
- FWCI
- 3.87
- Type
- journal article
- Language
- en
- Open access
- green
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
