The DOI matches its Crossref record; 24 of the 24 references it cites were found in a registry or an index.
Inflammation, fracture and bone repair
Open accessAbstract
The reconstitution of lost bone is a subject that is germane to many orthopaedic conditions including fractures and non-unions, infection, inflammatory arthritis, osteoporosis, osteonecrosis, metabolic bone disease, tumors, and periprosthetic particle-associated osteolysis. In this regard, the processes of acute and chronic inflammation play an integral role. Acute inflammation is initiated by endogenous or exogenous adverse stimuli, and can become chronic in nature if not resolved by normal homeostatic mechanisms. Dysregulated inflammation leads to increased bone resorption and suppressed bone formation. Crosstalk amongst inflammatory cells (polymorphonuclear leukocytes and cells of the monocyte-macrophage-osteoclast lineage) and cells related to bone healing (cells of the mesenchymal stem cell-osteoblast lineage and vascular lineage) is essential to the formation, repair and remodeling of bone. In this review, the authors provide a comprehensive summary of the literature related to inflammation and bone repair. Special emphasis is placed on the underlying cellular and molecular mechanisms, and potential interventions that can favorably modulate the outcome of clinical conditions that involve bone repair.
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Citations
Cites
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Cited by
Modulation of the Inflammatory Response and Bone Healing
Maruyama, M., Rhee, C., Utsunomiya, T., Zhang, N., Ueno, M., Yao, Z., & Goodman, S. B. (2020) · Frontiers in Endocrinology · doi:10.3389/fendo.2020.00386 · Cited by 541
Self-citationThe application of hyaluronic acid in bone regeneration
Zhai, P., Peng, X., Li, B., Liu, Y., Sun, H., & Li, X. (2020) · International Journal of Biological Macromolecules · doi:10.1016/j.ijbiomac.2019.10.169 · Cited by 438
More friend than foe: the emerging role of neutrophils in tissue repair
Peiseler, M., & Kubes, P. (2019) · Journal of Clinical Investigation · doi:10.1172/jci124616 · Cited by 423
The Role of the Immune Cells in Fracture Healing
Baht, G. S., Vi, L., & Alman, B. A. (2018) · Current Osteoporosis Reports · doi:10.1007/s11914-018-0423-2 · Cited by 275
Liu, Y., Zhu, Z., Pei, X., Zhang, X., Cheng, X., Hu, S., Gao, X., Wang, J., Chen, J., & Wan, Q. (2020) · ACS Applied Materials & Interfaces · doi:10.1021/acsami.0c12090 · Cited by 259
Metadata
- Authors
- Loi, F., Córdova, L. A., Pajarinen, J., Lin, T.-H., Yao, Z., & Goodman, S. B.
- Venue
- Bone
- Publisher
- Elsevier BV
- Published
- 2016-05
- Volume
- 86
- Pages
- 119-130
- ISSN
- 1873-2763 (ISSN-L)
- 8756-3282
- OpenAlex
- W2291522985
- Cited by
- 1,293
- References
- 24
- FWCI
- 37.32
- Type
- journal article
- Language
- en
- Open access
- green
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- Loi, F., Córdova, L. A., Pajarinen, J., Lin, T.-H., Yao, Z., & Goodman, S. B. (2016). Inflammation, fracture and bone repair. Bone. https://doi.org/10.1016/j.bone.2016.02.020
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
