Parenteral thyroxine administration
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Case reports have shown that parenteral (mostly intravenous) levothyroxine therapy can be used in patients with uncharacterised malabsorption.
“Case reports have shown that parenteral (mostly intravenous) levothyroxine therapy can be used in patients with uncharacterised malabsorption.159”
From Hypothyroidism (2024) · cites this paper as [159]
Some patients may experience considerable discomfort at subcutaneous injection sites.
“However, some patients may experience considerable discomfort at injection sites (236).”
From Levothyroxine: conventional and novel drug delivery formulations. (2023) · cites this paper as [236]
Cites
Aspects of the absorption of oral L-thyroxine in normal man
Wenzel, K. W., & Kirschsieper, H. E. (1977) · Metabolism · doi:10.1016/0026-0495(77)90121-4 · Cited by 151 · see citing works
L-Thyroxine Absorption in Patients with Short Bowel
STONE, E., LEITER, L. A., LAMBERT, J. R., SILVERBERG, J. D. H., JEEJEEBHOY, K. N., & BURROW, G. N. (1984) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jcem-59-1-139 · Cited by 66 · see citing works
Choe, W., & Hays, M. T. (1995) · The Endocrinologist · doi:10.1097/00019616-199505000-00009 · Cited by 34 · see citing works
Self-citationUnusual malabsorption of levothyroxine
Jauk, B., Mikosch, P., Gallowitsch, H. J., Kresnik, E., Molnar, M., Gomez, I., & Lind, P. (2000) · Thyroid · doi:10.1089/thy.2000.10.93 · Cited by 34 · see citing works
Intermittent Therapy with L-Thyroxine
Bernstein, R. S., & ROBBINS, J. J. (1969) · New England Journal of Medicine · doi:10.1056/nejm196912252812603 · Cited by 30 · see citing works
Tönjes, A., Karger, S., Koch, C. A., Paschke, R., Tannapfel, A., Stümvoll, M., & Führer, D. (2006) · Thyroid · doi:10.1089/thy.2006.16.1047 · Cited by 28 · see citing works
Hays, M. T., & McGUIRE, R. A. (1980) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jcem-51-5-1112 · Cited by 17 · see citing works
Self-citationTHEIN-WAI, W., & Larsen, P. R. (1980) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jcem-50-3-560 · Cited by 16 · see citing works
[A rare case of malabsorption of thyroid hormones].
Nobre, E. L., Jorge, Z., Anselmo, J., Lopes, C., César, R., Santos, V., & de Castro, J. J. (2004) · PubMed · Cited by 9 · see citing works
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Jonklaas, J., Bianco, A. C., Bauer, A. J., Burman, K. D., Cappola, A. R., Celi, F. S., Cooper, D. S., Kim, B. W., Peeters, R. P., Rosenthal, M. S., et al. (2014) · Thyroid® · doi:10.1089/thy.2014.0028 · Cited by 1,928 · see citing works
“Mathematical modeling of twice weekly or weekly administration of intramuscular LT4 showed some fluctuations of T4 levels, but with these levels remaining in the reference range (335).”
Treatment with thyroid hormone
Biondi, B., & Wartofsky, L. (2014) · Endocrine Reviews · doi:10.1210/er.2013-1083 · Cited by 259 · see citing works
Timing of levothyroxine administration affects serum thyrotropin concentration
Bach-Huynh, T.-G., Nayak, B., Loh, J., Soldin, S., & Jonklaas, J. (2009) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2009-0860 · Cited by 198 · see citing works
Taylor, P. N., Medici, M. M., Hubalewska-Dydejczyk, A., & Boelaert, K. (2024) · The Lancet · doi:10.1016/s0140-6736(24)01614-3 · Cited by 128 · see citing works
Eisenberg, M., Samuels, M., & DiStefano, J. J. (2008) · Thyroid · doi:10.1089/thy.2007.0388 · Cited by 65 · see citing works
Levothyroxine: conventional and novel drug delivery formulations.
Liu, H., Li, W., Zhang, W., Sun, S., & Chen, C. (2023) · Endocrine Reviews · doi:10.1210/endrev/bnac030 · Cited by 63 · see citing works
Levothyroxine absorption test results in patients with TSH elevation resistant to treatment
Yildirim Simsir, I., Soyaltin, U. E., & Ozgen, A. G. (2019) · Endocrine · doi:10.1007/s12020-019-01889-x · Cited by 16 · see citing works
Santos Monteiro, S., Santos, T. S., Lopes, A. M., Oliveira, J. C., Freitas, C., & Couto Carvalho, A. (2022) · Endocrine Connections · doi:10.1530/ec-22-0355 · Cited by 9 · see citing works
- Authors
- Hays, M. T.
- Affiliations
- VA Palo Alto Health Care System (US)
- Corresponding author
- Hays, Marguerite T.
- Venue
- Thyroid
- Publisher
- SAGE Publications
- Published
- 2007-02
- Volume
- 17
- Issue
- 2
- Pages
- 127-129
- ISSN
- 1050-7256 (ISSN-L)
- 1557-9077
- OpenAlex
- W2007054599
- Cited by
- 27
- References
- 9
- Citations by year
- 2025: 2 · 2024: 3 · 2023: 1 · 2022: 3 · 2021: 2 · 2019: 3 · 2016: 1 · 2015: 5 · 2014: 3
- FWCI
- 0.73
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Thyroid (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Thyroid Disorders and Treatments
- Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Thyroid Cancer Diagnosis and Treatment
- Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Adrenal Hormones and Disorders
- Keywords
- thyroxine, parenteral administration, thyroid hormone replacement
- MeSH terms
- Humans, Injections, Intramuscular, Intestinal Absorption, Models, Theoretical, Thyroxine
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
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