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Cited by 935

The DOI matches its Crossref record; 6 of the 6 references it cites were found in a registry or an index.

American Thyroid Association Guidelines for Management of Patients with Anaplastic Thyroid Cancer

Open access
Smallridge, Robert C., Ain, Kenneth B., Asa, Sylvia L., Bible, Keith C., Brierley, James D., Burman, Kenneth D., Kebebew, Electron, Lee, Nancy Y., Nikiforov, Yuri E., Rosenthal, M. Sara, Shah, Manisha H., Shaha, Ashok R., Tuttle for the American Thyroid Ass, R. Michael·2012·Thyroid

Abstract

BACKGROUND: Anaplastic thyroid cancer (ATC) is a rare but highly lethal form of thyroid cancer. Rapid evaluation and establishment of treatment goals are imperative for optimum patient management and require a multidisciplinary team approach. Here we present guidelines for the management of ATC. The development of these guidelines was supported by the American Thyroid Association (ATA), which requested the authors, members the ATA Taskforce for ATC, to independently develop guidelines for ATC. METHODS: Relevant literature was reviewed, including serial PubMed searches supplemented with additional articles. The quality and strength of recommendations were adapted from the Clinical Guidelines Committee of the American College of Physicians, which in turn was developed by the Grading of Recommendations Assessment, Development and Evaluation workshop. RESULTS: The guidelines include the diagnosis, initial evaluation, establishment of treatment goals, approaches to locoregional disease (surgery, radiotherapy, systemic therapy, supportive care during active therapy), approaches to advanced/metastatic disease, palliative care options, surveillance and long-term monitoring, and ethical issues including end of life. The guidelines include 65 recommendations. CONCLUSIONS: These are the first comprehensive guidelines for ATC and provide recommendations for management of this extremely aggressive malignancy. Patients with stage IVA/IVB resectable disease have the best prognosis, particularly if a multimodal approach (surgery, radiation, systemic therapy) is used, and some stage IVB unresectable patients may respond to aggressive therapy. Patients with stage IVC disease should be considered for a clinical trial or hospice/palliative care, depending upon their preference.

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Crossref · 10.1089/thy.2012.0302

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Metadata

Authors
Smallridge, R. C., Ain, K. B., Asa, S. L., Bible, K. C., Brierley, J. D., Burman, K. D., Kebebew, E., Lee, N. Y., Nikiforov, Y. E., Rosenthal, M. S., Shah, M. H., Shaha, A. R., & Tuttle for the American Thyroid Ass, R. M.
Venue
Thyroid
Published
2012-11
Volume
22
Issue
11
Pages
1104-1139
ISSN
  • 1050-7256 (ISSN-L)
  • 1557-9077
OpenAlex
W2113134419
Cited by
935
References
6
FWCI
30.83
Type
journal article
Language
en
Open access
green

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