The DOI matches its Crossref record; 1 of the 1 references it cites were found in a registry or an index.
The unfolded protein response coordinates the production of endoplasmic reticulum protein and endoplasmic reticulum membrane.
Open accessAbstract
The endoplasmic reticulum (ER) is a multifunctional organelle responsible for production of both lumenal and membrane components of secretory pathway compartments. Secretory proteins are folded, processed, and sorted in the ER lumen and lipid synthesis occurs on the ER membrane itself. In the yeast Saccharomyces cerevisiae, synthesis of ER components is highly regulated: the ER-resident proteins by the unfolded protein response and membrane lipid synthesis by the inositol response. We demonstrate that these two responses are intimately linked, forming different branches of the same pathway. Furthermore, we present evidence indicating that this coordinate regulation plays a role in ER biogenesis.
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Cites
Mutation of the mouse klotho gene leads to a syndrome resembling ageing
Kuro-o, M., Matsumura, Y., Aizawa, H., Kawaguchi, H., Suga, T., Utsugi, T., Ohyama, Y., Kurabayashi, M., Kaname, T., Kume, E., et al. (1997) · Nature · doi:10.1038/36285 · Cited by 3,837
Cited by
Sriburi, R., Jackowski, S., Mori, K., & Brewer, J. W. (2004) · The Journal of Cell Biology · doi:10.1083/jcb.200406136 · Cited by 653
Schuck, S., Prinz, W. A., Thorn, K. S., Voss, C., & Walter, P. (2009) · Journal of Cell Biology · doi:10.1083/jcb.200907074 · Cited by 580
Self-citationKochendörfer, K., Then, A. R., Kearns, B. G., Bankaitis, V. A., & Mayinger, P. (1999) · The EMBO Journal · doi:10.1093/emboj/18.6.1506 · Cited by 64
Scaling of Subcellular Structures
Marshall, W. F. (2020) · Annual Review of Cell and Developmental Biology · doi:10.1146/annurev-cellbio-020520-113246 · Cited by 54
Membrane biogenesis and the unfolded protein response
Ron, D., & Hampton, R. Y. (2004) · The Journal of Cell Biology · doi:10.1083/jcb.200408117 · Cited by 45
Metadata
- Authors
- Cox, J. S., Chapman, R. E., & Walter, P.
- Venue
- Molecular Biology of the Cell
- Published
- 1997-09
- Volume
- 8
- Issue
- 9
- Pages
- 1805-1814
- ISSN
- 1059-1524 (ISSN-L)
- 1939-4586
- OpenAlex
- W2148125211
- Cited by
- 403
- References
- 1
- FWCI
- 4.96
- Type
- journal article
- Language
- en
- Open access
- green
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- Cox, J. S., Chapman, R. E., & Walter, P. (1997). The unfolded protein response coordinates the production of endoplasmic reticulum protein and endoplasmic reticulum membrane. Molecular Biology of the Cell. https://doi.org/10.1091/mbc.8.9.1805
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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