CoChat
Sign Up
Cited by 162Dementia and Cognitive Impairment ResearchObesity, Physical Activity, DietCancer Risks and Factors

The DOI matches its Crossref record; 30 of the 32 references it cites were found in a registry or an index.

The risk of dementia with increased body mass index

Gorospe, E. C., Dave, J. K.·2006·Age and Ageing
DOI 10.1093/ageing/afl123
Open this paper in CoChat — free account

Abstract

BACKGROUND: identification of modifiable risk factors is crucial in the prevention of dementia, given its limited treatment options. Studies on increased body mass index (BMI) as a risk factor for dementia show conflicting results. METHODS: we systematically retrieved and reviewed longitudinal population-based studies on increased BMI and dementia using a standard protocol. We searched Medline (1966-2006), Ageline (1978-2006), PsychInfo (1966-2006), CINAHL (1982-2006), and other relevant databases, including the reference lists of the eligible articles for review. Included studies were subjected to a quality assessment protocol. RESULTS: we identified eight studies that met our selection criteria. These studies covered 1,688 cases of dementia from 28,697 participants. After adjustment for age, smoking, comorbidities, and other confounders, four studies presented significantly increased risk of dementia with elevated BMI. CONCLUSION: this systematic review supports the hypothesis that increased BMI is independently associated with increased risk of dementia. Long-term studies to examine the mechanisms underlying the relationship between obesity and dementia are needed.

Overview

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

A few free checks a day · papers already verified open instantly · results are public

Integrity signals

Registry

Crossref · 10.1093/ageing/afl123

Cites

30 of 30 references verified0 citation errors · 0 not checkable

Statistics

Verification

Claims the paper makes

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

A few free checks a day · papers already verified open instantly · results are public

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

Self-check

Percentages, sums and reported differences re-computed from the paper’s own numbers.

The self-check needs the paper’s full text.

Citations

Cites

Show all 32 references

Research works printed but not linked: 3

  1. The long list of references supporting this review has meant that only the most important are here and bold on the ://www.ageing.oxfordjournals.org/ as appendix 1.
  2. Centers of Disease Control and Prevention. Death: preliminary data 2003. Natl Vital Stat Rep 2005; 53: 2.
  3. Stroup DF, Berlin JA, Morton SC et al. Meta-analysis of observational studies in epidemiology: a proposal for reporting. Meta-analysis Of Observational Studies in Epidemiology (MOOSE) group. JAMA 2000; 283: 2008-12.

Cited by

Sorted by citations

Items 101–162 of 162

Related

See all

Metadata

Authors
Gorospe, E. C., & Dave, J. K.
Affiliations
Brigham and Women's Hospital (US)
Corresponding author
Gorospe, E. C.
ORCID
Dave, J. K.
Venue
Age and Ageing
Publisher
Oxford University Press (OUP)
Published
2006-11-17
Volume
36
Issue
1
Pages
23-29
ISSN
  • 0002-0729 (ISSN-L)
  • 1468-2834
DOI
10.1093/ageing/afl123
OpenAlex
W2155607826
Cited by
162
References
32
Citations by year
2026: 1 · 2025: 3 · 2024: 7 · 2023: 6 · 2022: 7 · 2021: 4 · 2020: 8 · 2019: 9 · 2018: 7 · 2017: 10 · 2016: 11 · 2015: 8 · 2014: 9 · 2013: 8 · 2012: 7
FWCI
1.33
Type
journal article
Language
en
Open access
closed
Locations
  • Age and Ageing (publishedVersion)
  • PubMed (publishedVersion)
Funders
Karolinska Institutet
Topics
  • Health Sciences › Medicine › Psychiatry and Mental health › Dementia and Cognitive Impairment Research
  • Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Obesity, Physical Activity, Diet
  • Health Sciences › Medicine › Oncology › Cancer Risks and Factors
Keywords
dementia, body mass index, obesity, dementia risk factors, modifiable risk factors, dementia prevention, longitudinal cohort
MeSH terms
Adult, Aged, Aged, 80 and over, Dementia, Female, Humans, Longitudinal Studies, Male, Middle Aged, Obesity, Risk Factors, Body Mass Index

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review