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Cited by 824Clinical Nutrition and GastroenterologyBody Composition Measurement TechniquesNutrition and Health in Aging

The DOI matches its Crossref record; 18 of the 19 references it cites were found in a registry or an index.

The Harris Benedict equation reevaluated: resting energy requirements and the body cell mass

Roza, A M, Shizgal, H M·1984·The American Journal of Clinical Nutrition
DOI 10.1093/ajcn/40.1.168
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Abstract

The Harris Benedict equations (HBE) were derived from indirect calorimetric data obtained in 239 normal subjects. Using these data and additional data published by Benedict, which were obtained from subjects spanning a wider age range (n = 98), the present study evaluated the relationship between measured resting energy expenditure and age, sex, and predicted body cell mass (BCM). When the additional subjects from the subsequently published series are included, the regression equations, standard error of the estimate, and 95% confidence limits are similar to the original equations. The HBE estimate resting energy expenditure of a normal subject with a precision of 14%. Resting energy expenditure is directly related to the size of the BCM and is independent of age and sex. The variables of height, weight, age, and sex in the HBE reflect the relationship between body weight and the BCM. Indirect calorimetry and body composition measurements were performed in both normally nourished and malnourished patients (n = 74) to assess the accuracy of the HBE in malnourished patients. Malnutrition is associated with an increase in resting oxygen consumption (VO2) which becomes apparent only when VO2 is expressed as a function of the BCM. There is no difference in resting VO2 between the sexes when expressed as a function of BCM. A regression equation was derived from the Harris Benedict data to predict resting VO2 from age, height, weight, and sex. Predicted VO2 was not significantly different from measured VO2 for the normally nourished patients (n = 33) whereas in the malnourished (n = 41) predicted VO2 underestimated the measured value. The HBE accurately predict resting energy expenditure in normally nourished individuals with a precision of +/- 14%, but are unreliable in the malnourished patient.

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Crossref · 10.1093/ajcn/40.1.168

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Citations

Cites

Research works printed but not linked: 6

  1. Kinney JM. The application of indirect calorimetry to clinical studies. In Kinney JM ed. Assessment of energy metabolism in health and disease. Report of the First Ross Conference on Medical Research. Columbus, OH: Ross Laboratories, 1980:42-8.
  2. Armitage P. Statistical methods in medical research. New York, NY: John Wiley and Sons, 1971.
  3. Forse, 1980, The Nae/Ke ratio: a predictor of malnutrition., Surg Forum, 31, 89
  4. Forse, 1981, Effect of malnutrition on oxygen consumption., Surg Forum, 32, 99
  5. Grande F. Energy expenditure of tissue and organs. In: Kinney JM, ed. Assessment of energy metabolism in health and disease. Report of the First Ross Conference on Medical Research. Columbus, OH: Ross Laboratories, 1980:88-92.
  6. Stewart, 1981, Energy expenditure in the critically ill ventilated patient., JPEN, 5

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Metadata

Authors
Roza, A. M., & Shizgal, H. M.
Corresponding author
Shizgal, H M
Venue
The American Journal of Clinical Nutrition
Publisher
Elsevier BV
Published
1984-07
Volume
40
Issue
1
Pages
168-182
ISSN
0002-9165 (ISSN-L)
DOI
10.1093/ajcn/40.1.168
OpenAlex
W2125884465
Semantic Scholar
379f53c98ea8429493ffe111f85b57dd87adcaeb
Cited by
824
References
19
Citations by year
2026: 31 · 2025: 45 · 2024: 40 · 2023: 45 · 2022: 42 · 2021: 45 · 2020: 58 · 2019: 48 · 2018: 41 · 2017: 52 · 2016: 35 · 2015: 48 · 2014: 25 · 2013: 24 · 2012: 16
FWCI
9.64
Type
journal article
Language
en
Open access
closed
Licence
Locations
  • American Journal of Clinical Nutrition (publishedVersion)
  • PubMed (publishedVersion)
Topics
  • Health Sciences › Nursing › Nutrition and Dietetics › Clinical Nutrition and Gastroenterology
  • Health Sciences › Medicine › Physiology (medical) › Body Composition Measurement Techniques
  • Health Sciences › Medicine › Physiology (medical) › Nutrition and Health in Aging
Keywords
Harris-Benedict equation, resting energy expenditure, body cell mass, indirect calorimetry, resting oxygen consumption, malnutrition, body composition, load forecasting, regression equations, sex differences
MeSH terms
Adult, Age Factors, Aged, Body Composition, Body Weight, Calorimetry, Indirect, Deficiency Diseases, Energy Metabolism, Female, Humans, Male, Middle Aged, Oxygen Consumption, Regression Analysis, Sex Factors

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