Insulin: its relationship to the central nervous system and to the control of food intake and body weight

Hypothalamic and genetic obesity in experimental animals: an autonomic and endocrine hypothesis

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Chronic intracerebroventricular infusion of insulin reduces food intake and body weight of baboons

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Hunger: Basic mechanisms and clinical implications

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Neural control of the endocrine pancreas.

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Increased feeding in response to decreased glucose utilization in the rat and monkey

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Pancreatic Neuroendocrinology: Peripheral Neural Mechanisms in the Regulation of the Islets of Langerhans*

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Eating and Its Disorders

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Central nervous system regulation of liver and adipose tissue metabolism

Shimazu, T. (1981) · Diabetologia · doi:10.1007/bf00254502 · Cited by 261 · see citing works

Effect of Vagotomy and Vagal Stimulation on Insulin Secretion

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Glucose‐sensitive afferent nerve fibres in the hepatic branch of the vagus nerve in the guinea‐pig.

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Reduction of food intake and body weight by chronic intraventricular insulin infusion

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Regional Concentrations of Insulin in the Rat Brain*

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Hyperalimentation in Normal Animals Produced by Protamine Insulin

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Insulin and insulin receptors in rodent brain

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Metabolic hormones and regulation of body weight.

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Insulin acting as a modulator of feeding through the hypothalamus

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Regulation of food intake and body weight by insulin

Porte, D., & Woods, S. C. (1981) · Diabetologia · doi:10.1007/bf00254493 · Cited by 174 · see citing works

Metering of intravenous versus oral nutrients and regulation of energy balance

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Increased feeding in response to bilateral injection of insulin antibodies in the VMH

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Diabetes Mellitus. Theory and Practice

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Neural Regulation of Insulin Secretion in the Dog

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Genetically obese zucker rats have abnormally low brain insulin content

Baskin, D. G., Stein, L. J., Ikeda, H., Woods, S. C., Figlewicz, D. P., Porte, D., Greenwood, M. R. C., & Dorsa, D. M. (1985) · Life Sciences · doi:10.1016/0024-3205(85)90166-3 · Cited by 138 · see citing works

Immunocytochemical Detection of Insulin in Rat Hypothalamus and Its Possible Uptake from Cerebrospinal Fluid*

Baskin, D. G., Woods, S. C., West, D. B., van Houten, M., Posner, B. I., Dorsa, D. M., & Porte, D. (1983) · Endocrinology · doi:10.1210/endo-113-5-1818 · Cited by 122 · see citing works

Textbook of Endocrinology.

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Neuropharmacology of the Pancreatic Islets

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Direct enhancement of insulin secretion by vagal stimulation of the isolated pancreas

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Neural pathways involved in the hypothalamic integration of autonomic responses

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Chronic insulin infusion suppresses food ingestion and body weight gain in Rats

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Increases in Plasma Insulin Levels in Response to Electrical Stimulation of the Dorsal Motor Nucleus of the Vagus Nerve*

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Hyperinsulinemia of preobese and obese fa/fa rats is partly vagus nerve mediated

Rohner‐Jeanrenaud, F., Hochstrasser, A.-C., & Jeanrenaud, B. (1983) · American Journal of Physiology-Endocrinology and Metabolism · doi:10.1152/ajpendo.1983.244.4.e317 · Cited by 83 · see citing works

Effect of Intracisternal Insulin on Plasma Glucose and Insulin in the Dog

Woods, S. C., & Porte, D. (1975) · Diabetes · doi:10.2337/diab.24.10.905 · Cited by 80 · see citing works

Comparative measurements of glucose, beta-hydroxybutyrate, acetoacetate, and insulin in blood and cerebrospinal fluid during starvation

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Cellular basis of direct insulin action in the central nervous system

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Effect of Cerebral Intraventricular Insulin on Pancreatic Insulin Secretion in the Dog

Chen, M., Woods, S. C., & Porte, D. (1975) · Diabetes · doi:10.2337/diab.24.10.910 · Cited by 79 · see citing works

IMMUNOREACTIVE INSULIN LEVELS ARE ELEVATED IN THE CEREBROSPINAL FLUID OF GENETICALLY OBESE ZUCKER RATS

Stein, L. J., Dorsa, D. M., Baskin, D. G., Figlewicz, D. P., Ikeda, H., Frarikmann, S. P., Greenwood, M. R. C., Porte, D., & Woods, S. C. (1983) · Endocrinology · doi:10.1210/endo-113-6-2299 · Cited by 75 · see citing works

Effect of Force-Feeding Upon Basal Insulin Levels of Rats

Bernstein, I. L., Lotter, E. C., Kulkosky, P. J., Porte, D., & Woods, S. C. (1975) · Experimental Biology and Medicine · doi:10.3181/00379727-150-39075 · Cited by 67 · see citing works

Injections of insulin and changes of body weight

Lotter, E. C., & Woods, S. C. (1977) · Physiology & Behavior · doi:10.1016/0031-9384(77)90136-6 · Cited by 65 · see citing works

The role of glucose in insulin-induced feeding and drinking☆

Booth, D., & ELISABETHPITT, M. (1968) · Physiology & Behavior · doi:10.1016/0031-9384(68)90076-0 · Cited by 64 · see citing works

Lateral hypothalamic control of metabolic factors related to feeding

Nicolaïdis, S. (1981) · Diabetologia · doi:10.1007/bf00254512 · Cited by 55 · see citing works

The modulatory effect of the hypothalamus on glucagon and insulin secretion in the rat

Steffens, A. B. (1981) · Diabetologia · doi:10.1007/bf00254510 · Cited by 52 · see citing works

CNS Regulation of Carbohydrate Metabolism

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The brain-islet axis: the nervous control of the endocrine pancreas.

Helman, A., Marre, M., Bobbioni, E., Poussier, P., Reach, G., & Assan, R. (1982) · PubMed · Cited by 38 · see citing works

Cephalic insulin response as a test for completeness of vagotomy to the pancreas

Woods, S. C., & Bernstein, I. L. (1980) · Physiology & Behavior · doi:10.1016/0031-9384(80)90241-3 · Cited by 36 · see citing works

Visceral afferent and efferent connections in the brain

Novin, D., Rogers, R. C., & Hermann, G. E. (1981) · Diabetologia · doi:10.1007/bf00254500 · Cited by 36 · see citing works

Nervous control of peripheral metabolism.

Shimazu, T. (1979) · PubMed · Cited by 35 · see citing works

Interactions between autonomic nerves and endocrine cells of the gastroenteropancreatic system

Smith, P. H., & Madson, K. L. (1981) · Diabetologia · doi:10.1007/bf00254498 · Cited by 31 · see citing works

Effect of Rat Hypothalamic Extract Administration on Insulin Secretion in Vivo*

Bobbioni, E., & Jeanrenaud, B. (1982) · Endocrinology · doi:10.1210/endo-110-2-631 · Cited by 21 · see citing works

Metabolic hormones and regulation of feeding: A reply to Woods, Decke, and Vasselli.

Panksepp, J. (1975) · Psychological Review · doi:10.1037/h0076800 · Cited by 9 · see citing works

Cerebrospinal fluid leptin levels: Relationship to plasma levels and to adiposity in humans

Schwartz, M. W., Peskind, E., Raskind, M., Boyko, E. J., & Porte, D. (1996) · Nature Medicine · doi:10.1038/nm0596-589 · Cited by 1,014 · see citing works

Saturable transport of insulin from plasma into the central nervous system of dogs in vivo. A mechanism for regulated insulin delivery to the brain.

Baura, G. D., Foster, D. M., Porte, D., Kahn, S. E., Bergman, R. N., Cobelli, C., & Schwartz, M. W. (1993) · Journal of Clinical Investigation · doi:10.1172/jci116773 · Cited by 489 · see citing works

Obesity in Type 1 Diabetes: Pathophysiology, Clinical Impact, and Mechanisms

Corbin, K. D., Driscoll, K. A., Pratley, R. E., Smith, S. R., Maahs, D. M., Mayer-Davis, E. J., & Advancing Care for Type 1 Diabetes and Obesity Network (ACT1ON) (2018) · Endocrine Reviews · doi:10.1210/er.2017-00191 · Cited by 262 · see citing works

Evidence for entry of plasma insulin into cerebrospinal fluid through an intermediate compartment in dogs. Quantitative aspects and implications for transport.

Schwartz, M. W., Bergman, R. N., Kahn, S. E., Taborsky, G. J., Fisher, L. D., Sipols, A. J., Woods, S. C., Steil, G. M., & Porte, D. (1991) · Journal of Clinical Investigation · doi:10.1172/jci115431 · Cited by 183 · see citing works

Insulin receptors in the pituitary gland: morphological evidence for influence on opioid peptide-synthesizing cells

Unger, J. W., & Lange, W. (1997) · Cell and Tissue Research · doi:10.1007/s004410050833 · Cited by 45 · see citing works

Classically conditioned responses following repeated insulin and glucose administration in humans

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Evaluation of the lack of anorectic effect of intracerebroventricular insulin in rats

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A mathematical model of brain glucose homeostasis

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Effects of chlordecone on food intake and body weight in the male rat.

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Influence of Estrogens on Body Growth and Food Intake.

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The ingestion of food and the recovery of body weight following fasting in the naive rat

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Effects of para-chlorophenylalanine on food intake in rats

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[Seasonal fluctuations of food intake and bodyweight in the dormouse Glis glis (author's transl)].

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