The DOI matches its Crossref record; 54 of the 54 references it cites were found in a registry or an index.
Cigarette Smoking and Incidence of First Depressive Episode: An 11-Year, Population-based Follow-up Study
Abstract
Smoking has been found to be associated with depression. Biologic hypotheses support causation in both directions. This study examined the association between cigarette smoking and a subsequent first depression. In 1990, 2,014 adults in Norway were interviewed about their lifestyle and mental health. A 2001 reinterview by trained interviewers defined the study cohort of 1,190 participants. The cases were those who experienced a first depression whose onset was estimated to occur during the follow-up period, based on retrospective assessment by the Composite International Diagnostic Interview (International Classification of Diseases, Tenth Revision). Cox regression was used to estimate the hazard rate of depression during follow-up. Alternative explanations for a direct causal influence from smoking on subsequent depression were assessed, and a sensitivity analysis was performed. The risk of depression was four times as high for heavy smokers compared with never smokers. A dose-response relation with an increasing hazard for past smokers and for an increasing number of cigarettes smoked per day for current smokers was found. Similarly, increasing smoking time was associated with increasing risk. Failure of other plausible alternatives to explain the observed association between smoking and depression might reflect a direct causal influence of smoking on depression.
Overview
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
In the citing paper
“the risk of developing depression was four times higher in heavy smokers than nonsmokers and increased time of smoking dependency was correlated with increased risk of depression (Klungsøyr, Nygård, Sørensen, & Sandanger, 2006)”
From Nicotine addiction and psychiatric disorders (2015) · cites this paper as Klungsøyr et al., 2006
Citations
Cites
Murray, C. J. L., & López, A. D. (1997) · The Lancet · doi:10.1016/s0140-6736(96)07492-2 · Cited by 7,007
Proportional hazards tests and diagnostics based on weighted residuals
GRAMBSCH, P. M., & THERNEAU, T. M. (1994) · Biometrika · doi:10.1093/biomet/81.3.515 · Cited by 5,885 · cited 1×
“Both global and covariate-specific tests for assumptions of proportional hazards were performed (31).”
BackgroundThe Hopkins Symptom Checklist (HSCL): A self-report symptom inventory
Derogatis, L. R., Lipman, R. S., Rickels, K., Uhlenhuth, E. H., & Covi, L. (1974) · Behavioral Science · doi:10.1002/bs.3830190102 · Cited by 4,604
Robins, L. N. (1988) · Archives of General Psychiatry · doi:10.1001/archpsyc.1988.01800360017003 · Cited by 2,909
A structural approach to selection bias
Hernán, M. A., Hernández-Díaz, S., & Robins, J. M. (2004) · Epidemiology · doi:10.1097/01.ede.0000135174.63482.43 · Cited by 2,844 · cited 1×
“This relies on the assumption of no other strong, unmeasured confounder between somatic decline and depression (49, 50).”
BackgroundDieting and binging: A causal analysis.
Polivy, J., & Herman, C. P. (1985) · American Psychologist · doi:10.1037//0003-066x.40.2.193 · Cited by 1,279
The detection of psychiatric illness by questionnaire
Goldberg, D. P. (1972) · Oxford University Press eBooks · Cited by 1,191
The psychometric properties of the Composite International Diagnostic Interview
Andrews, G., & Peters, L. (1998) · Social Psychiatry and Psychiatric Epidemiology · doi:10.1007/s001270050026 · Cited by 881
PSYCHOSOCIAL FACTORS AND CARDIOVASCULAR DISEASES
Everson‐Rose, S. A., & Lewis, T. T. (2005) · Annual Review of Public Health · doi:10.1146/annurev.publhealth.26.021304.144542 · Cited by 838
Smoking and Major Depression: A Causal Analysis
Kendler, K. S. (1993) · Archives of General Psychiatry · doi:10.1001/archpsyc.1993.01820130038007 · Cited by 792
Inhibition of monoamine oxidase B in the brains of smokers
Fowler, J. S., Volkow, N. D., Wang, G., Pappas, N. R., Logan, J., MacGregor, R. R., Alexoff, D. L., Shea, C. E., Schlyer, D. J., Wolf, A. P., et al. (1996) · Nature · doi:10.1038/379733a0 · Cited by 657
Major Depression and Stages of Smoking
Breslau, N., Peterson, E. L., Schultz, L. R., Chilcoat, H. D., & Andreski, P. M. (1998) · Archives of General Psychiatry · doi:10.1001/archpsyc.55.2.161 · Cited by 650
Nicotine dependence, major depression, and anxiety in young adults
Breslau, N. (1991) · Archives of General Psychiatry · doi:10.1001/archpsyc.1991.01810360033005 · Cited by 634
Basic methods for sensitivity analysis of biases.
Greenland, S. (1996) · International Journal of Epidemiology · doi:10.1093/ije/25.6.1107 · Cited by 605
Fallibility in estimating direct effects
Cole, S. R., & Hernán, M. A. (2002) · International Journal of Epidemiology · doi:10.1093/ije/31.1.163 · Cited by 548
Depression, anxiety, and smoking initiation: a prospective study over 3 years
Patton, G. C., Carlin, J. B., Coffey, C., Wolfe, R., Hibbert, M., & Bowes, G. (1998) · American Journal of Public Health · doi:10.2105/ajph.88.10.1518 · Cited by 513
Marginal Structural Models to Estimate the Joint Causal Effect of Nonrandomized Treatments
Hernán, M. Á., Brumback, B., & Robins, J. M. (2001) · Journal of the American Statistical Association · doi:10.1198/016214501753168154 · Cited by 483
Trends in cigarette smoking in the United States. The changing influence of gender and race
Fiore, M. C. (1989) · JAMA · doi:10.1001/jama.261.1.49 · Cited by 450
Nicotine Dependence and Major Depression: New Evidence From a Prospective Investigation
Breslau, N. (1993) · Archives of General Psychiatry · doi:10.1001/archpsyc.1993.01820130033006 · Cited by 443
A population-based twin study in women of smoking initiation and nicotine dependence
Kendler, K. S., Neale, M. C., Sullivan, P. F., Corey, L. A., GARDNER, C. O., & Prescott, C. A. (1999) · Psychological Medicine · doi:10.1017/s0033291798008022 · Cited by 442
Trends in cigarette smoking in the United States. Educational differences are increasing
Pierce, J. P. (1989) · JAMA · doi:10.1001/jama.261.1.56 · Cited by 419
Depressive Symptoms and Cigarette Smoking Among Teens
Goodman, E., & Capitman, J. (2000) · Pediatrics · doi:10.1542/peds.106.4.748 · Cited by 416
Symptoms of Emotional Distress in a Family Planning Service: Stability over a Four-Week Period
Winokur, A., Winokur, D. F., Rickels, K., & Cox, D. S. (1984) · British Journal of Psychiatry · doi:10.1192/bjp.144.4.395 · Cited by 390
Major depression and cigarette smoking: Results of a 21-year longitudinal study
FERGUSSON, D. M., GOODWIN, R. D., & HORWOOD, L. J. (2003) · Psychological Medicine · doi:10.1017/s0033291703008596 · Cited by 374
Avison, W. R., & Turner, R. J. (1988) · Journal of Health and Social Behavior · doi:10.2307/2137036 · Cited by 365
Sandanger, I., Moum, T., Ingebrigtsen, G., Dalgard, O. S., Sørensen, T., & Bruusgaard, D. (1998) · Social Psychiatry and Psychiatric Epidemiology · doi:10.1007/s001270050064 · Cited by 326
Epidemiology of Tobacco Use and Dependence
Giovino, G. A., Henningfield, J. E., Tomar, S. L., Escobedo, L. G., & SLADE, J. D. (1995) · Epidemiologic Reviews · doi:10.1093/oxfordjournals.epirev.a036185 · Cited by 285
The interview for recent life events
PAYKEL, E. S. (1997) · Psychological Medicine · doi:10.1017/s0033291796004424 · Cited by 275
Trends in Cigarette Smoking in the United States
Garfinkel, L. (1997) · Preventive Medicine · doi:10.1006/pmed.1997.0191 · Cited by 261
Wittchen, H.-U. (1989) · Archives of General Psychiatry · doi:10.1001/archpsyc.1989.01810050051009 · Cited by 219
Cigarette smoking predicts development of depressive symptoms among U.S. Adolescents
Choi, W. S., Patten, C. A., Christian Gillin, J., Kaplan, R. M., & Pierce, J. P. (1997) · Annals of Behavioral Medicine · doi:10.1007/bf02883426 · Cited by 208
Comorbidity Between Depressive Disorders and Nicotine Dependence in a Cohort of 16-Year-Olds
Fergusson, D. M. (1996) · Archives of General Psychiatry · doi:10.1001/archpsyc.1996.01830110081010 · Cited by 200
Peters, L., & Andrews, G. (1995) · Psychological Medicine · doi:10.1017/s0033291700033237 · Cited by 179
Rickels, K., García, C.-R., Lipman, R. S., Derogatis, L. R., & Fisher, E. (1976) · Primary Care Clinics in Office Practice · doi:10.1016/s0095-4543(21)00578-9 · Cited by 162
The Genetics of Smoking Persistence in Men and Women: A Multicultural Study
Madden, P. A. F., Heath, A. C., Pedersen, N. L., Kaprio, J. A., Koskenvuo, M. J., & Martin, N. G. (1999) · Behavior Genetics · doi:10.1023/a:1021674804714 · Cited by 154
Sandanger, I., Moum, T., Ingebrigtsen, G., Sørensen, T., Dalgard, O. S., & Bruusgaard, D. (1999) · Social Psychiatry and Psychiatric Epidemiology · doi:10.1007/s001270050112 · Cited by 137
Reasons Women Do Not Attend Screening for Cervical Cancer: A Population-Based Study in Sweden
Eaker, S., Adami, H.-O., & Sparén, P. (2001) · Preventive Medicine · doi:10.1006/pmed.2001.0844 · Cited by 137
Prevalence, incidence and age at onset of psychiatric disorders in Norway
Sandanger, I., Nygård, J. F., Ingebrigtsen, G., Sørensen, T., & Dalgard, O. S. (1999) · Social Psychiatry and Psychiatric Epidemiology · doi:10.1007/s001270050177 · Cited by 136
Genetic and environmental risk factors in adolescent substance use
Silberg, J. L., Rutter, M. L., D'Onofrio, B. M., & Eaves, L. J. (2003) · Journal of Child Psychology and Psychiatry · doi:10.1111/1469-7610.00153 · Cited by 134
Smoking and mental health: results from a community survey
Jorm, A. F., Rodgers, B., Jacomb, P. A., Christensen, H. M., Henderson, S., & Korten, A. E. (1999) · The Medical Journal of Australia · doi:10.5694/j.1326-5377.1999.tb126887.x · Cited by 124
Euphoriant effects of nicotine in smokers
Pomerleau, C. S., & Pomerleau, O. F. (1992) · Psychopharmacology · doi:10.1007/bf02247422 · Cited by 120
Interacting Effects of Genetic Predisposition and Depression on Adolescent Smoking Progression
Audrain-McGovern, J. E., Lerman, C. E., Wileyto, E. P., Rodriguez, D., & Shields, P. G. (2004) · American Journal of Psychiatry · doi:10.1176/appi.ajp.161.7.1224 · Cited by 117
Is women?s mental health more susceptible than men?s to the influence of surrounding stress?
Sandanger, I., Nygård, J. F., S�rensen, T. I. A., & Moum, T. (2004) · Social Psychiatry and Psychiatric Epidemiology · doi:10.1007/s00127-004-0728-6 · Cited by 114
Elucidating the role of genetic factors in smoking behavior and nicotine dependence
Lerman, C., & Berrettini, W. (2003) · American Journal of Medical Genetics Part B: Neuropsychiatric Genetics · doi:10.1002/ajmg.b.10003 · Cited by 114
Onset of major depression during treatment for nicotine dependence
Killen, J. D., Fortmann, S. P., Schatzberg, A. F., Hayward, C., & Varady, A. N. (2003) · Addictive Behaviors · doi:10.1016/s0306-4603(01)00266-0 · Cited by 81
Ismail, K. (2000) · American Journal of Epidemiology · doi:10.1093/aje/152.7.651 · Cited by 63
Smoking and depressive symptoms in Chinese elderly in Hong Kong
Lam, T., Li, Z. B., Ho, S. Y., Chan, W. M., Ho, K. S., Li, M. P., & Leung, G. M. (2004) · Acta Psychiatrica Scandinavica · doi:10.1111/j.1600-0447.2004.00342.x · Cited by 54
Psychoneurotic profiles of smokers and non-smokers.
Haines, A., Imeson, J., & Meade, T. W. (1980) · BMJ · doi:10.1136/bmj.280.6229.1422 · Cited by 51
Albers, A. B., & Biener, L. (2002) · Preventive Medicine · doi:10.1006/pmed.2002.1029 · Cited by 50
Thompson, R., Bogner, H. R., Coyne, J. C., Gallo, J. J., & Eaton, W. W. (2004) · Acta Psychiatrica Scandinavica · doi:10.1111/j.1600-0447.2003.00284.x · Cited by 36
Smoking and depression: a community survey.
Frerichs, R. R., Aneshensel, C. S., Clark, V. A., & Yokopenic, P. A. (1981) · American Journal of Public Health · doi:10.2105/ajph.71.6.637 · Cited by 36
Cervilla, J. A., Prince, M. J., Joels, S., Russ, C., & Lovestone, S. (2004) · American Journal of Geriatric Psychiatry · doi:10.1097/00019442-200403000-00011 · Cited by 24
Depression and Smoking: Examining Correlates in a Subset of Depressed Patients
Roy, K., Parker, G. B., Mitchell, P. B., & Wilhelm, K. A. (2001) · Australian & New Zealand Journal of Psychiatry · doi:10.1046/j.1440-1614.2001.00889.x · Cited by 20
Genetic Screening for Susceptibility to Depression: Can We and Should We?
Morley, K. I., Hall, W., & Carter, L. (2004) · Australian & New Zealand Journal of Psychiatry · doi:10.1111/j.1440-1614.2004.01300.x · Cited by 18
Research works printed but not linked: 2
- Lund KE, Lund M. Smoking and inequality in Norway 1998–2000. (In Norwegian). Tidsskr Nor Laegeforen2005;125:560–3.
- Saunders JB, Aasland OG. WHO collaborative on identification and treatment of persons with harmful alcohol consumption. Oslo, Norway: World Health Organization, 1987:97.
Cited by
Sorted by citations
The association of cigarette smoking with depression and anxiety: a systematic review
Fluharty, M., Taylor, A. E., Grabski, M., & Munafò, M. R. (2017) · Nicotine & Tobacco Research · doi:10.1093/ntr/ntw140 · Cited by 1,299
Tobacco use and cessation in psychiatric disorders: National Institute of Mental Health report
Ziedonis, D., Hitsman, B., Beckham, J. C., Zvolensky, M., Adler, L. E., Audrain-McGovern, J., Breslau, N., Brown, R. A., George, T. P., Williams, J., et al. (2008) · Nicotine & Tobacco Research · doi:10.1080/14622200802443569 · Cited by 735
Nicotine and the adolescent brain
Yuan, M., Cross, S. J., Loughlin, S. E., & Leslie, F. M. (2015) · The Journal of Physiology · doi:10.1113/jp270492 · Cited by 623
“2009), a finding that supports the concept that teen smoking may not only be co-morbid with mood-related disorders but may actually induce them (John et al. 2004; Klungsoyr et al. 2006; Flensborg-Madsen et al. 2011).”
BackgroundSmoking, Mental Illness, and Public Health
Prochaska, J. J., Das, S., & Young-Wolff, K. C. (2017) · Annual Review of Public Health · doi:10.1146/annurev-publhealth-031816-044618 · Cited by 503
“Depression is twice as common in smokers than nonsmokers, and four times as common in heavy smokers (66).”
BackgroundCigarette smoking and depression: tests of causal linkages using a longitudinal birth cohort
Boden, J. M., Fergusson, D. M., & Horwood, L. J. (2010) · British Journal of Psychiatry · doi:10.1192/bjp.bp.109.065912 · Cited by 477
Metadata
- Authors
- Klungsøyr, O., Nygård, J. F., Sørensen, T., & Sandanger, I.
- Affiliations
- University of Oslo (NO)
- Corresponding author
- Klungsøyr, Ole
- Venue
- American Journal of Epidemiology
- Publisher
- Oxford University Press (OUP)
- Published
- 2006-01-04
- Volume
- 163
- Issue
- 5
- Pages
- 421-432
- ISSN
- 0002-9262 (ISSN-L)
- 1476-6256
- OpenAlex
- W2152013172
- Cited by
- 269
- References
- 54
- Citations by year
- 2026: 2 · 2025: 3 · 2024: 9 · 2023: 6 · 2022: 5 · 2021: 14 · 2020: 28 · 2019: 12 · 2018: 9 · 2017: 9 · 2016: 7 · 2015: 21 · 2014: 17 · 2013: 16 · 2012: 17
- FWCI
- 10.94
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- American Journal of Epidemiology (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Smoking Behavior and Cessation
- Health Sciences › Medicine › Psychiatry and Mental health › Mental Health Treatment and Access
- Health Sciences › Medicine › Epidemiology › Substance Abuse Treatment and Outcomes
- Keywords
- cigarette smoking, depression, first-episode depression, dose-response relationship, smoking duration, heavy smoking, causal inference, mental health
- MeSH terms
- Adult, Aged, Aged, 80 and over, Depressive Disorder, Female, Follow-Up Studies, Humans, Male, Middle Aged, Norway, Prospective Studies, Surveys and Questionnaires, Risk Factors, Smoking, Time Factors, Incidence, Confidence Intervals, Proportional Hazards Models
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review