Cited by 198Physical Activity and HealthCardiovascular and exercise physiologyExercise and Physiological Responses

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Does Strength-Promoting Exercise Confer Unique Health Benefits? A Pooled Analysis of Data on 11 Population Cohorts With All-Cause, Cancer, and Cardiovascular Mortality Endpoints

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Stamatakis, Emmanuel, Lee, I -Min, Bennie, Jason, Freeston, Jonathan, Hamer, Mark, O’Donovan, Gary, Ding, Ding, Bauman, Adrian, Mavros, Yorgi·2018·American Journal of Epidemiology

DOI 10.1093/aje/kwx345

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Abstract

Public health guidance includes recommendations to engage in strength-promoting exercise (SPE), but there is little evidence on its links with mortality. Using data from the Health Survey for England and the Scottish Health Survey from 1994-2008, we examined the associations between SPE (gym-based and own-body-weight strength activities) and all-cause, cancer, and cardiovascular disease mortality. Multivariable-adjusted Cox regression was used to examine the associations between SPE (any, low-/high-volume, and adherence to the SPE guideline (≥2 sessions/week)) and mortality. The core sample comprised 80,306 adults aged ≥30 years, corresponding to 5,763 any-cause deaths (736,463 person-years). Following exclusions for prevalent disease/events occurring in the first 24 months, participation in any SPE was favorably associated with all-cause (hazard ratio (HR) = 0.77, 95% confidence interval (CI): 0.69, 0.87) and cancer (HR = 0.69, 95% CI: 0.56, 0.86) mortality. Adhering only to the SPE guideline was associated with all-cause (HR = 0.79, 95% CI: 0.66, 0.94) and cancer (HR = 0.66, 95% CI: 0.48, 0.92) mortality; adhering only to the aerobic activity guideline (equivalent to 150 minutes/week of moderate-intensity activity) was associated with all-cause (HR = 0.84, 95% CI: 0.78, 0.90) and cardiovascular disease (HR = 0.78, 95% CI: 0.68, 0.90) mortality. Adherence to both guidelines was associated with all-cause (HR = 0.71, 95% CI: 0.57, 0.87) and cancer (HR = 0.70, 95% CI: 0.50, 0.98) mortality. Our results support promoting adherence to the strength exercise guidelines over and above the generic physical activity targets.

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Authors: Stamatakis, E., Lee, I. M., Bennie, J., Freeston, J., Hamer, M., O’Donovan, G., Ding, D., Bauman, A., & Mavros, Y.
Affiliations: The University of Sydney (AU)
Brigham and Women's Hospital (US)
Victoria University (AU)
Loughborough University (GB)
Corresponding author: Stamatakis, Emmanuel
ORCID: Stamatakis, Emmanuel
Lee, I -Min
Bennie, Jason
Freeston, Jonathan
Hamer, Mark
O’Donovan, Gary
Ding, Ding
Bauman, Adrian
Mavros, Yorgi
Venue: American Journal of Epidemiology
Publisher: Oxford University Press (OUP)
Published: 2017-10-31
Volume: 187
Issue: 5
Pages: 1102-1112
ISSN: 0002-9262 (ISSN-L)
1476-6256
DOI: 10.1093/aje/kwx345
OpenAlex: W2766901730
Cited by: 198
References: 48
Citations by year: 2026: 14 · 2025: 22 · 2024: 17 · 2023: 16 · 2022: 32 · 2021: 29 · 2020: 33 · 2019: 17 · 2018: 18
FWCI: 13.75
Type: journal article
Language: en
Open access: bronze
doi.org
Licence: academic.oup.com/journals/pages/about_us/legal/notices (vor)
Locations: American Journal of Epidemiology (publishedVersion)
PubMed (publishedVersion)
Victoria University Research Repository (Victoria University) (submittedVersion)
Loughborough University Institutional Repository (Loughborough University) (submittedVersion, cc-by-nc-nd)
Loughborough University Research Repository (Loughborough University) (submittedVersion, cc-by-nc-nd)
Funders: National Institute for Health Research
National Health and Medicine Research Council
National Institute for Health Research Leicester Biomedical Research Center
Topics: Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Physical Activity and Health
Health Sciences › Medicine › Physiology (medical) › Cardiovascular and exercise physiology
Health Sciences › Medicine › Physiology (medical) › Exercise and Physiological Responses
Keywords: resistance training, all-cause mortality, cancer mortality, cardiovascular mortality, physical activity guidelines, exercise adherence, gym-based exercise, aerobic exercise, Health Survey for England, Scottish Health Survey
MeSH terms: Adult, Aged, Cardiovascular Diseases, Cause of Death, England, Female, Health Promotion, Health Surveys, Humans, Male, Middle Aged, Neoplasms, Population Surveillance, Scotland, Cohort Studies, Resistance Training

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Does Strength-Promoting Exercise Confer Unique Health Benefits? A Pooled Analysis of Data on 11 Population Cohorts With All-Cause, Cancer, and Cardiovascular Mortality Endpoints

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