The DOI matches its Crossref record; 2 of the 2 references it cites were found in a registry or an index.
ASEdb: a database of alanine mutations and their effects on the free energy of binding in protein interactions
Open accessAbstract
Summary: The Alanine Scanning Energetics database (ASEdb) is a searchable database of single alanine mutations in protein–protein, protein–nucleic acid, and protein–small molecule interactions for which binding affinities have been experimentally determined. In cases where structures are available, it contains surface areas of the mutated side chain and links to the PDB entries. It is useful for studying the contribution of single amino acids to the energetics of protein interactions, and can be updated by researchers as new data are generated. Availability: ASEdb is accessible on the Web at http://www.asedb.org Contact: thorn@itsa.ucsf.edu * To whom correspondence should be addressed.
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Citations
Cites
Principles of protein-protein interactions
Jones, S., & Thornton, J. M. (1996) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.93.1.13 · Cited by 2,684
Anatomy of hot spots in protein interfaces
Bogan, A. A., & Thorn, K. S. (1998) · Journal of Molecular Biology · doi:10.1006/jmbi.1998.1843 · Cited by 1,988
Self-citation
Cited by
Lu, H., Zhou, Q., He, J., Jiang, Z., Peng, C., Tong, R., & Shi, J. (2020) · Signal Transduction and Targeted Therapy · doi:10.1038/s41392-020-00315-3 · Cited by 891
A simple physical model for binding energy hot spots in protein–protein complexes
Kortemme, T., & Baker, D. (2002) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.202485799 · Cited by 804
Unraveling hot spots in binding interfaces: progress and challenges
DeLano, W. L. (2002) · Current Opinion in Structural Biology · doi:10.1016/s0959-440x(02)00283-x · Cited by 767
Hot spots—A review of the protein–protein interface determinant amino‐acid residues
Moreira, I. S., Fernandes, P. A., & Ramos, M. J. (2007) · Proteins: Structure, Function, and Bioinformatics · doi:10.1002/prot.21396 · Cited by 760
Principles of Protein−Protein Interactions: What are the Preferred Ways For Proteins To Interact?
Keskin, O., Gursoy, A., Ma, B., & Nussinov, R. (2008) · Chemical Reviews · doi:10.1021/cr040409x · Cited by 697
Metadata
- Authors
- Thorn, K. S., & Bogan, A. A.
- Venue
- Bioinformatics
- Publisher
- Oxford University Press (OUP)
- Published
- 2001-03-01
- Volume
- 17
- Issue
- 3
- Pages
- 284-285
- ISSN
- 1367-4803 (ISSN-L)
- 1367-4811
- OpenAlex
- W2157735020
- Cited by
- 403
- References
- 2
- FWCI
- 2.28
- Type
- journal article
- Language
- en
- Open access
- bronze
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- Thorn, K. S., & Bogan, A. A. (2001). ASEdb: a database of alanine mutations and their effects on the free energy of binding in protein interactions. Bioinformatics. https://doi.org/10.1093/bioinformatics/17.3.284
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