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Generating samples under a Wright–Fisher neutral model of genetic variation

Open access
Hudson, Richard R.·2002·Bioinformatics

Abstract

Summary: A Monte Carlo computer program is available to generate samples drawn from a population evolving according to a Wright–Fisher neutral model. The program assumes an infinite-sites model of mutation, and allows recombination, gene conversion, symmetric migration among subpopulations, and a variety of demographic histories. The samples produced can be used to investigate the sampling properties of any sample statistic under these neutral models. Availability: The source code for the program (in the language C) is available at http://home.uchicago.edu/~rhudson1/source/mksamples.html. Contact: rr-hudson@uchicago.edu

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Crossref · 10.1093/bioinformatics/18.2.337

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Authors
Hudson, R. R.
Venue
Bioinformatics
Published
2002-02-01
Volume
18
Issue
2
Pages
337-338
ISSN
  • 1367-4803 (ISSN-L)
  • 1367-4811
OpenAlex
W2134599124
Cited by
2,364
References
0
FWCI
25.68
Type
journal article
Language
en
Open access
bronze

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