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Cited by 441

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ProPred1: prediction of promiscuous MHC Class-I binding sites

Open access
Singh, Harpreet, Raghava, G.P.S.·2003·Bioinformatics

Abstract

Summary: ProPred1 is an on-line web tool for the prediction of peptide binding to MHC class-I alleles. This is a matrix-based method that allows the prediction of MHC binding sites in an antigenic sequence for 47 MHC class-I alleles. The server represents MHC binding regions within an antigenic sequence in user-friendly formats. These formats assist user in the identification of promiscuous MHC binders in an antigen sequence that can bind to large number of alleles. ProPred1 also allows the prediction of the standard proteasome and immunoproteasome cleavage sites in an antigenic sequence. This server allows identification of MHC binders, who have the cleavage site at the C terminus. The simultaneous prediction of MHC binders and proteasome cleavage sites in an antigenic sequence leads to the identification of potential T-cell epitopes. Availability: Server is available at http://www.imtech.res.in/raghava/propred1/. Mirror site of this server is available at http://bioinformatics.uams.edu/mirror/propred1/ Supplementary information: Matrices and document on server are available at http://www.imtech.res.in/raghava/propred1/page2.html Contact: raghava@imtech.res.in * To whom correspondence should be addressed at Bioinformatics Centre, Institute of Microbial Technology, Sector 39A, Chandigarh, India.

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Metadata

Authors
Singh, H., & Raghava, G. P. S.
Venue
Bioinformatics
Published
2003-05-22
Volume
19
Issue
8
Pages
1009-1014
ISSN
  • 1367-4803 (ISSN-L)
  • 1367-4811
OpenAlex
W2132609988
Cited by
441
References
14
FWCI
3.11
Type
journal article
Language
en
Open access
bronze

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CoChat. (2026). Citation check: ProPred1: prediction of promiscuous MHC Class-I binding sites. https://app.cochat.ai/papers/10.1093/bioinformatics/btg108
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Singh, H., & Raghava, G. P. S. (2003). ProPred1: prediction of promiscuous MHC Class-I binding sites. Bioinformatics. https://doi.org/10.1093/bioinformatics/btg108

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