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Cited by 389

The DOI matches its Crossref record; 22 of the 22 references it cites were found in a registry or an index.

Development of epitope‐based peptide vaccine against novel coronavirus 2019 (SARS‐COV‐2): Immunoinformatics approach

Open access
Bhattacharya, Manojit, Sharma, Ashish R., Patra, Prasanta, Ghosh, Pratik, Sharma, Garima, Patra, Bidhan C., Lee, Sang‐Soo, Chakraborty, Chiranjib·2020·Journal of Medical Virology

Abstract

Recently, a novel coronavirus (SARS‐COV‐2) emerged which is responsible for the recent outbreak in Wuhan, China. Genetically, it is closely related to SARS‐CoV and MERS‐CoV. The situation is getting worse and worse, therefore, there is an urgent need for designing a suitable peptide vaccine component against the SARS‐COV‐2. Here, we characterized spike glycoprotein to obtain immunogenic epitopes. Next, we chose 13 Major Histocompatibility Complex‐(MHC) I and 3 MHC‐II epitopes, having antigenic properties. These epitopes are usually linked to specific linkers to build vaccine components and molecularly dock on toll‐like receptor‐5 to get binding affinity. Therefore, to provide a fast immunogenic profile of these epitopes, we performed immunoinformatics analysis so that the rapid development of the vaccine might bring this disastrous situation to the end earlier.

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Metadata

Authors
Bhattacharya, M., Sharma, A. R., Patra, P., Ghosh, P., Sharma, G., Patra, B. C., Lee, S., & Chakraborty, C.
Venue
Journal of Medical Virology
Publisher
Wiley
Published
2020-03-05
Volume
92
Issue
6
Pages
618-631
ISSN
  • 0146-6615 (ISSN-L)
  • 1096-9071
OpenAlex
W3007407747
Cited by
389
References
22
FWCI
24.96
Type
journal article
Language
en
Open access
bronze

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CoChat. (2026). Citation check: Development of epitope‐based peptide vaccine against novel coronavirus 2019 (SARS‐COV‐2): Immunoinformatics approach. https://app.cochat.ai/papers/10.1002/jmv.25736
The paper
Bhattacharya, M., Sharma, A. R., Patra, P., Ghosh, P., Sharma, G., Patra, B. C., Lee, S., & Chakraborty, C. (2020). Development of epitope‐based peptide vaccine against novel coronavirus 2019 (SARS‐COV‐2): Immunoinformatics approach. Journal of Medical Virology. https://doi.org/10.1002/jmv.25736

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