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The DOI matches its Crossref record; 94 of the 94 references it cites were found in a registry or an index.

Bioimage informatics: a new area of engineering biology

Open access
Peng, Hanchuan·2008·Bioinformatics

Abstract

In recent years, the deluge of complicated molecular and cellular microscopic images creates compelling challenges for the image computing community. There has been an increasing focus on developing novel image processing, data mining, database and visualization techniques to extract, compare, search and manage the biological knowledge in these data-intensive problems. This emerging new area of bioinformatics can be called ‘bioimage informatics’. This article reviews the advances of this field from several aspects, including applications, key techniques, available tools and resources. Application examples such as high-throughput/high-content phenotyping and atlas building for model organisms demonstrate the importance of bioimage informatics. The essential techniques to the success of these applications, such as bioimage feature identification, segmentation and tracking, registration, annotation, mining, image data management and visualization, are further summarized, along with a brief overview of the available bioimage databases, analysis tools and other resources. Contact: pengh@janelia.hhmi.org Supplementary information: Supplementary data are available at Bioinformatics online.

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Metadata

Authors
Peng, H.
Venue
Bioinformatics
Published
2008-07-04
Volume
24
Issue
17
Pages
1827-1836
ISSN
  • 1367-4803 (ISSN-L)
  • 1367-4811
OpenAlex
W2154917588
Cited by
346
References
94
FWCI
15.22
Type
journal article
Language
en
Open access
hybrid

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CoChat. (2026). Citation check: Bioimage informatics: a new area of engineering biology. https://app.cochat.ai/papers/10.1093/bioinformatics/btn346
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Peng, H. (2008). Bioimage informatics: a new area of engineering biology. Bioinformatics. https://doi.org/10.1093/bioinformatics/btn346

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