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CellProfiler: image analysis software for identifying and quantifying cell phenotypes

Open access
Carpenter, Anne E, Jones, Thouis R, Lamprecht, Michael R, Clarke, Colin, Kang, In Han, Friman, Ola, Guertin, David A, Chang, Joo Han, Lindquist, Robert A, Moffat, Jason, Golland, Polina, Sabatini, David M·2006·Genome Biology
DOI 10.1186/gb-2006-7-10-r100
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Abstract

Biologists can now prepare and image thousands of samples per day using automation, enabling chemical screens and functional genomics (for example, using RNA interference). Here we describe the first free, open-source system designed for flexible, high-throughput cell image analysis, CellProfiler. CellProfiler can address a variety of biological questions quantitatively, including standard assays (for example, cell count, size, per-cell protein levels) and complex morphological assays (for example, cell/organelle shape or subcellular patterns of DNA or protein staining).

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Metadata

Authors
Carpenter, A. E., Jones, T. R., Lamprecht, M. R., Clarke, C., Kang, I. H., Friman, O., Guertin, D. A., Chang, J. H., Lindquist, R. A., Moffat, J., Golland, P., & Sabatini, D. M.
Venue
Genome Biology
Publisher
Springer Science and Business Media LLC
Published
2006-10-31
Volume
7
Issue
10
Pages
R100-R100
ISSN
  • 1465-6906 (ISSN-L)
  • 1474-760X
DOI
10.1186/gb-2006-7-10-r100
OpenAlex
W2107554012
Cited by
5,157
References
3
FWCI
28.53
Type
journal article
Language
en
Open access
gold
Licence

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CoChat. (2026). Citation check: CellProfiler: image analysis software for identifying and quantifying cell phenotypes. https://app.cochat.ai/papers/10.1186/gb-2006-7-10-r100
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Carpenter, A. E., Jones, T. R., Lamprecht, M. R., Clarke, C., Kang, I. H., Friman, O., Guertin, D. A., Chang, J. H., Lindquist, R. A., Moffat, J., Golland, P., & Sabatini, D. M. (2006). CellProfiler: image analysis software for identifying and quantifying cell phenotypes. Genome Biology. https://doi.org/10.1186/gb-2006-7-10-r100

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