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DADP: the database of anuran defense peptides

Novković, Mario, Simunić, Juraj, Bojović, Viktor, Tossi, Alessandro, Juretić, Davor·2012·Bioinformatics

Abstract

Summary: Anuran tissues, and especially skin, are a rich source of bioactive peptides and their precursors. We here present a manually curated database of antimicrobial and other defense peptides with a total of 2571 entries, most of them in the precursor form with demarcated signal peptide (SP), acidic proregion(s) and bioactive moiety(s) corresponding to 1923 non-identical bioactive sequences. Search functions on the corresponding web server facilitate the extraction of six distinct SP classes. The more conserved of these can be used for searching cDNA and UniProtKB databases for potential bioactive peptides, for creating PROSITE search patterns, and for phylogenetic analysis. Availability: DADP is accessible at http://split4.pmfst.hr/dadp/ Contact: juretic@pmfst.hr Supplementary information: Supplementary data are available at Bioinformatics online.

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Research works printed but not linked: 22

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Metadata

Authors
Novković, M., Simunić, J., Bojović, V., Tossi, A., & Juretić, D.
Venue
Bioinformatics
Published
2012-03-29
Volume
28
Issue
10
Pages
1406-1407
ISSN
  • 1367-4803 (ISSN-L)
  • 1367-4811
OpenAlex
W2147454197
Cited by
218
References
0
FWCI
7.28
Type
journal article
Language
en
Open access
closed

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CoChat. (2026). Citation check: DADP: the database of anuran defense peptides. https://app.cochat.ai/papers/10.1093/bioinformatics/bts141
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Novković, M., Simunić, J., Bojović, V., Tossi, A., & Juretić, D. (2012). DADP: the database of anuran defense peptides. Bioinformatics. https://doi.org/10.1093/bioinformatics/bts141

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