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DADP: the database of anuran defense peptides
Abstract
Summary: Anuran tissues, and especially skin, are a rich source of bioactive peptides and their precursors. We here present a manually curated database of antimicrobial and other defense peptides with a total of 2571 entries, most of them in the precursor form with demarcated signal peptide (SP), acidic proregion(s) and bioactive moiety(s) corresponding to 1923 non-identical bioactive sequences. Search functions on the corresponding web server facilitate the extraction of six distinct SP classes. The more conserved of these can be used for searching cDNA and UniProtKB databases for potential bioactive peptides, for creating PROSITE search patterns, and for phylogenetic analysis. Availability: DADP is accessible at http://split4.pmfst.hr/dadp/ Contact: juretic@pmfst.hr Supplementary information: Supplementary data are available at Bioinformatics online.
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Cited by
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Torres, M. D. T., Sothiselvam, S., Lu, T. K., & de la Fuente-Nunez, C. (2019) · Journal of Molecular Biology · doi:10.1016/j.jmb.2018.12.015 · Cited by 438
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Bin Hafeez, A., Jiang, X., Bergen, P. J., & Zhu, Y. (2021) · International Journal of Molecular Sciences · doi:10.3390/ijms222111691 · Cited by 341
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“The training set consists of 1554 AMP sequences, which are collected from three publicly opened databases: the database of Anuran defense peptides (DADP) 38 , the antimicrobial peptide database (APD) 39 , and the a database for antimicrobial peptides (ADAM) 40 .”
In Silico Models for Designing and Discovering Novel Anticancer Peptides
Tyagi, A., Kapoor, P., Kumar, R., Chaudhary, K., Gautam, A., & Raghava, G. P. S. (2013) · Scientific Reports · doi:10.1038/srep02984 · Cited by 320
Metadata
- Authors
- Novković, M., Simunić, J., Bojović, V., Tossi, A., & Juretić, D.
- Venue
- Bioinformatics
- Publisher
- Oxford University Press (OUP)
- Published
- 2012-03-29
- Volume
- 28
- Issue
- 10
- Pages
- 1406-1407
- ISSN
- 1367-4803 (ISSN-L)
- 1367-4811
- OpenAlex
- W2147454197
- Cited by
- 218
- References
- 0
- FWCI
- 7.28
- Type
- journal article
- Language
- en
- Open access
- closed
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- Novković, M., Simunić, J., Bojović, V., Tossi, A., & Juretić, D. (2012). DADP: the database of anuran defense peptides. Bioinformatics. https://doi.org/10.1093/bioinformatics/bts141
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