The DOI matches its Crossref record; 101 of the 101 references it cites were found in a registry or an index.
Robot-based hand motor therapy after stroke
Open accessAbstract
Robots can improve motor status after stroke with certain advantages, but there has been less emphasis to date on robotic developments for the hand. The goal of this study was to determine whether a hand-wrist robot would improve motor function, and to evaluate the specificity of therapy effects on brain reorganization. Subjects with chronic stroke producing moderate right arm/hand weakness received 3 weeks therapy that emphasized intense active movement repetition as well as attention, speed, force, precision and timing, and included virtual reality games. Subjects initiated hand movements. If necessary, the robot completed movements, a feature available at all visits for seven of the subjects and at the latter half of visits for six of the subjects. Significant behavioural gains were found at end of treatment, for example, in Action Research Arm Test (34 +/- 20 to 38 +/- 19, P< 0.0005) and arm motor Fugl-Meyer score (45 +/- 10 to 52 +/- 10, P < 0.0001). Results suggest greater gains for subjects receiving robotic assistance in all sessions as compared to those receiving robotic assistance in half of sessions. The grasp task practiced during robotic therapy, when performed during functional MRI, showed increased sensorimotor cortex activation across the period of therapy, while a non-practiced task, supination/pronation, did not. A robot-based therapy showed improvements in hand motor function after chronic stroke. Reorganization of motor maps during the current therapy was task-specific, a finding useful when considering generalization of rehabilitation therapy.
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Cites
The assessment and analysis of handedness: The Edinburgh inventory
Oldfield, R. C. (1971) · Neuropsychologia · doi:10.1016/0028-3932(71)90067-4 · Cited by 35,900
Measurements of acute cerebral infarction: a clinical examination scale.
Brott, T., Adams, H. P., Olinger, C. P., Marler, J. R., Barsan, W. G., Biller, J., Spilker, J., Holleran, R., Eberle, R., & Hertzberg, V (1989) · Stroke · doi:10.1161/01.str.20.7.864 · Cited by 5,911
The post-stroke hemiplegic patient. 1. a method for evaluation of physical performance
Fugl-Meyer, A., Jääskö, L., Leyman, I., Olsson, S., & Steglind, S. (1975) · Journal of Rehabilitation Medicine · doi:10.2340/1650197771331 · Cited by 5,564
More hippocampal neurons in adult mice living in an enriched environment
Kempermann, G., Kuhn, H. G., & Gage, F. H. (1997) · Nature · doi:10.1038/386493a0 · Cited by 3,511
AN IMPLICIT TECHNOLOGY OF GENERALIZATION 1
Stokes, T. F., & Baer, D. M. (1977) · Journal of Applied Behavior Analysis · doi:10.1901/jaba.1977.10-349 · Cited by 3,351
Neural consequences of enviromental enrichment
van Praag, H., Kempermann, G., & Gage, F. H. (2000) · Nature Reviews Neuroscience · doi:10.1038/35044558 · Cited by 2,468
Region of interest analysis using an SPM toolbox
Brett, M. (2002) · NeuroImage · Cited by 2,273
Adult Norms for the Box and Block Test of Manual Dexterity
Mathiowetz, V., Volland, G., Kashman, N., & Weber, K. (1985) · The American Journal of Occupational Therapy · doi:10.5014/ajot.39.6.386 · Cited by 2,105
Wolf, S. L., Winstein, C. J., Miller, J. P., Taub, E., Uswatte, G., Morris, D., Giuliani, C., Light, K. E., Nichols-Larsen, D., & EXCITE Investigators, F. T. (2006) · JAMA · doi:10.1001/jama.296.17.2095 · Cited by 1,889
Functional MRI evidence for adult motor cortex plasticity during motor skill learning
Kami, A., Meyer, G., Jezzard, P., Adams, M. M., Turner, R., & Ungerleider, L. G. (1995) · Nature · doi:10.1038/377155a0 · Cited by 1,883
Cited by
Harnessing neuroplasticity for clinical applications
Cramer, S. C., Sur, M., Dobkin, B. H., O'Brien, C., Sanger, T. D., Trojanowski, J. Q., Rumsey, J. M., Hicks, R., Cameron, J., Chen, D., et al. (2011) · Brain · doi:10.1093/brain/awr039 · Cited by 1,259
Self-citationWhat Is the Evidence for Physical Therapy Poststroke? A Systematic Review and Meta-Analysis
Veerbeek, J. M., van Wegen, E., van Peppen, R., van der Wees, P. J., Hendriks, E., Rietberg, M., & Kwakkel, G. (2014) · PLoS ONE · doi:10.1371/journal.pone.0087987 · Cited by 1,203
Review of control strategies for robotic movement training after neurologic injury
Marchal-Crespo, L., & Reinkensmeyer, D. J. (2009) · Journal of NeuroEngineering and Rehabilitation · doi:10.1186/1743-0003-6-20 · Cited by 1,182
Mehrholz, J., Pohl, M., Platz, T., Kugler, J., & Elsner, B. (2015) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd006876.pub4 · Cited by 678
Robot-assisted Therapy in Stroke Rehabilitation
Chang, W. H., & Kim, Y.-H. (2013) · Journal of Stroke · doi:10.5853/jos.2013.15.3.174 · Cited by 499
Metadata
- Authors
- Takahashi, C. D., Der-Yeghiaian, L., Le, V., Motiwala, R. R., & Cramer, S. C.
- Venue
- Brain
- Publisher
- Oxford University Press (OUP)
- Published
- 2008-02-01
- Volume
- 131
- Issue
- 2
- Pages
- 425-437
- ISSN
- 0006-8950 (ISSN-L)
- 1460-2156
- OpenAlex
- W2136192280
- Cited by
- 624
- References
- 101
- FWCI
- 25.95
- Type
- journal article
- Language
- en
- Open access
- bronze
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