The DOI matches its Crossref record; 3 of the 3 references it cites were found in a registry or an index.
Emerging role of KLF4 in human gastrointestinal cancer
Abstract
Recent analyses revealed that Krüppel-like factors (KLFs) play important roles in both normal development and carcinogenesis. Of the 16 known KLFs, KLF4 has been shown to be involved in the regulation of proliferation, differentiation and tumorigenesis of gastrointestinal tract epithelium. Clinical, experimental and mechanistic findings indicate that KLF4 is a bona fide tumor suppressor for both gastric and colorectal cancers. In this review, we summarize how this growing area of research has formed and the challenging new frontiers for better understanding of the oncogenic potential of the KLFs.
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Cites
Lessons from hereditary colorectal cancer
Kinzler, K. W., & Vogelstein, B. (1996) · Cell · doi:10.1016/s0092-8674(00)81333-1 · Cited by 4,919
Requirement for p53 and p21 to Sustain G 2 Arrest After DNA Damage
Bunz, F., Dutriaux, A., Lengauer, C., Waldman, T., Zhou, S., Brown, J. P., Sedivy, J. M., Kinzler, K. W., & Vogelstein, B. (1998) · Science · doi:10.1126/science.282.5393.1497 · Cited by 2,803
The biology of the mammalian Krüppel-like family of transcription factors
Dang, D. T., Pevsner, J., & Yang, V. W. (2000) · The International Journal of Biochemistry & Cell Biology · doi:10.1016/s1357-2725(00)00059-5 · Cited by 458
Cited by
Mammalian Krüppel-Like Factors in Health and Diseases
McConnell, B. B., & Yang, V. W. (2010) · Physiological Reviews · doi:10.1152/physrev.00058.2009 · Cited by 1,018
Krüppel-like factor 4 (KLF4): What we currently know
Ghaleb, A. M., & Yang, V. W. (2017) · Gene · doi:10.1016/j.gene.2017.02.025 · Cited by 523
KLF4-dependent perivascular cell plasticity mediates pre-metastatic niche formation and metastasis
Murgai, M., Ju, W., Eason, M., Kline, J., Beury, D. W., Kaczanowska, S., Miettinen, M. M., Kruhlak, M., Lei, H., Shern, J. F., et al. (2017) · Nature Medicine · doi:10.1038/nm.4400 · Cited by 263
miR-7 Suppresses Brain Metastasis of Breast Cancer Stem-Like Cells By Modulating KLF4
Okuda, H., Xing, F., Pandey, P. R., Sharma, S., Watabe, M., Pai, S. K., Mo, Y.-Y., Iiizumi-Gairani, M., Hirota, S., Liu, Y., et al. (2013) · Cancer Research · doi:10.1158/0008-5472.can-12-2037 · Cited by 285
Embryonic stem cell markers expression in cancers
Schoenhals, M., Kassambara, A., Vos, J. D., Hose, D., Moreaux, J., & Klein, B. (2009) · Biochemical and Biophysical Research Communications · doi:10.1016/j.bbrc.2009.02.156 · Cited by 265
Metadata
- Authors
- Wei, D., Kanai, M., Huang, S., & Xie, K.
- Venue
- Carcinogenesis
- Publisher
- Oxford University Press (OUP)
- Published
- 2005-01-01
- Volume
- 27
- Issue
- 1
- Pages
- 23-31
- ISSN
- 0143-3334 (ISSN-L)
- 1460-2180
- OpenAlex
- W2163711719
- Cited by
- 224
- References
- 3
- FWCI
- 1.84
- Type
- journal article
- Language
- en
- Open access
- closed
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