The DOI matches its Crossref record; 125 of the 125 references it cites were found in a registry or an index.
Immunosuppression associated with chronic inflammation in the tumor microenvironment
Open accessAbstract
Chronic inflammation contributes to cancer development via multiple mechanisms. One potential mechanism is that chronic inflammation can generate an immunosuppressive microenvironment that allows advantages for tumor formation and progression. The immunosuppressive environment in certain chronic inflammatory diseases and solid cancers is characterized by accumulation of proinflammatory mediators, infiltration of immune suppressor cells and activation of immune checkpoint pathways in effector T cells. In this review, we highlight recent advances in our understanding of how immunosuppression contributes to cancer and how proinflammatory mediators induce the immunosuppressive microenvironment via induction of immunosuppressive cells and activation of immune checkpoint pathways.
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Cites
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Friedmann Angeli, J. P., Krysko, D. V., & Conrad, M. (2019) · Nature Reviews Cancer · doi:10.1038/s41568-019-0149-1 · Cited by 1,259
Ferroptosis in cancer: from molecular mechanisms to therapeutic strategies
Zhou, Q., Meng, Y., Li, D., Yao, L., Le, J., Liu, Y., Sun, Y., Zeng, F., Chen, X., & Deng, G. (2024) · Signal Transduction and Targeted Therapy · doi:10.1038/s41392-024-01769-5 · Cited by 890
The emerging role of ferroptosis in inflammation
Sun, Y., Chen, P., Zhai, B., Zhang, M., Xiang, Y., Fang, J., Xu, S., Gao, Y., Chen, X., Sui, X., et al. (2020) · Biomedicine & Pharmacotherapy · doi:10.1016/j.biopha.2020.110108 · Cited by 739
Senescent cell clearance by the immune system: Emerging therapeutic opportunities
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Salminen, A., Kaarniranta, K., & Kauppinen, A. (2022) · Inflammation Research · doi:10.1007/s00011-022-01598-8 · Cited by 432
Metadata
- Authors
- Wang, D., & DuBois, R. N.
- Venue
- Carcinogenesis
- Publisher
- Oxford University Press (OUP)
- Published
- 2015-09-08
- Volume
- 36
- Issue
- 10
- Pages
- 1085-1093
- ISSN
- 0143-3334 (ISSN-L)
- 1460-2180
- OpenAlex
- W2234490399
- Cited by
- 355
- References
- 125
- FWCI
- 9.62
- Type
- journal article
- Language
- en
- Open access
- green
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- Wang, D., & DuBois, R. N. (2015). Immunosuppression associated with chronic inflammation in the tumor microenvironment. Carcinogenesis. https://doi.org/10.1093/carcin/bgv123
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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