Global Distribution of O Serotypes and Antibiotic Resistance in Extraintestinal Pathogenic Escherichia coli Collected From the Blood of Patients With Bacteremia Across Multiple Surveillance Studies
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Background: Extraintestinal pathogenic Escherichia coli (ExPEC) is the leading cause of bacteremia worldwide, with older populations having increased risk of invasive bacterial disease. Increasing resistance to first-line antibiotics and emergence of multidrug-resistant (MDR) strains represent major treatment challenges. ExPEC O serotypes are key targets for potential multivalent conjugate vaccine development. Therefore, we evaluated the O serotype distribution and antibiotic resistance profiles of ExPEC strains causing bloodstream infections across 4 regions. Methods: Blood culture isolates from patients aged ≥60 years collected during 5 retrospective E. coli surveillance studies in Europe, North America, Asia-Pacific, and South America (2011–2017) were analyzed. Isolates were O serotyped by agglutination; O genotyping was performed for nontypeable isolates. Antimicrobial susceptibility testing was also conducted. Results: Among 3217 ExPEC blood culture isolates, the most ubiquitous O serotype was O25 (n = 737 [22.9%]), followed by O2, O6, O1, O75, O15, O8, O16, O4, O18, O77 group, O153, O9, O101/O162, O86, and O13 (prevalence of ≥1%). The prevalence of these O serotypes was generally consistent across regions, apart from South America; together, these 16 O serotypes represented 77.6% of all ExPEC bacteremia isolates analyzed. The overall MDR frequency was 10.7%, with limited variation between regions. Within the MDR subset (n = 345), O25 showed a dominant prevalence of 63.2% (n = 218). Conclusions: Predominant O serotypes among ExPEC bacteremia isolates are widespread across different regions. O25 was the most prevalent O serotype overall and particularly dominant among MDR isolates. These findings may inform the design of multivalent conjugate vaccines that can target the predominant O serotypes associated with invasive ExPEC disease in older adults.
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E. coli Nissle 1917 has O6 repeating units for LPS, K5-type capsule, and H1-type flagella.
“having O6 repeating units for LPS (a feature commonly found in extra-intestinal pathogenic E. coli strains), K5-type for capsule (described to make serum-resistant the extra-intestinal pathogenic E. coli strains), and H1-type for flagella (responsible for strain motility) [26, 29, 30]”
From Selection, Comparative Genomics, and Potential Probiotic Features of Escherichia coli 5C, a pks-Negative Strain Isolated from Healthy Infant Donor Feces (2026) · cites this paper as [30]
The Results (Other Prevalent Serotypes; page not provided) report that O6 accounted for 8.1% of the ExPEC bloodstream isolates studied, supporting the parenthetical description of O6 as common in ExPEC. Our copy does not identify E. coli Nissle 1917 as O6 or address its K5 capsule, H1 flagella, serum resistance, or motility. (LLM, conf=0.88)
Experimental — accuracy not yet measuredE. coli Nissle 1917 is characterized by an LPS-type O6, commonly found in extra-intestinal pathogenic E. coli.
“E. coli Nissle 1917 is characterized by an LPS-type, O6, commonly found in extra-intestinal pathogenic E. coli [29, 30, 146].”
From Selection, Comparative Genomics, and Potential Probiotic Features of Escherichia coli 5C, a pks-Negative Strain Isolated from Healthy Infant Donor Feces (2026) · cites this paper as [30]
The Results (“Other Prevalent Serotypes”; page unavailable) report that O6 accounted for 8.1% of the ExPEC bacteremia isolates and was common across regions. The paper also identifies the O antigen as part of lipopolysaccharide, but it does not establish that E. coli Nissle 1917 has the O6 type. (LLM, conf=0.88)
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Cites
Magiorakos, A.-P., Srinivasan, A., Carey, R. B., Carmeli, Y., Falagas, M. E., Giske, C. G., Harbarth, S., Hindler, J. F., Kahlmeter, G., Olsson-Liljequist, B., et al. (2012) · Clinical Microbiology and Infection · doi:10.1111/j.1469-0691.2011.03570.x · Cited by 14,449 · see citing works
Maiden, M. C. J., Bygraves, J. A., Feil, E. J., Morelli, G., Russell, J. E., Urwin, R., Zhang, Q., Zhou, J., Zurth, K., Caugant, D. A., et al. (1998) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.95.6.3140 · Cited by 3,838 · see citing works
BIGSdb: Scalable analysis of bacterial genome variation at the population level
Jolley, K. A., & Maiden, M. C. J. (2010) · BMC Bioinformatics · doi:10.1186/1471-2105-11-595 · Cited by 2,341 · see citing works
Humphries, R. M., Bobenchik, A. M., Hindler, J. A., & Schuetz, A. N. (2021) · Journal of Clinical Microbiology · doi:10.1128/jcm.00213-21 · Cited by 1,538 · see citing works
Serology, chemistry, and genetics of O and K antigens of Escherichia coli
Ørskov, I., Ørskov, F., Jann, B., & Jann, K. (1977) · Bacteriological Reviews · doi:10.1128/br.41.3.667-710.1977 · Cited by 933 · see citing works
Russo, T. A., & Johnson, J. R. (2003) · Microbes and Infection · doi:10.1016/s1286-4579(03)00049-2 · Cited by 801 · see citing works
BSAC standardized disc susceptibility testing method (version 7)
Andrews, J. M., & Testing, F. T. B. W. P. O. S. (2008) · Journal of Antimicrobial Chemotherapy · doi:10.1093/jac/dkn194 · Cited by 737 · see citing works
Weiner, L. M., Abner, S., Edwards, J. R., Kallen, A. J., Karlsson, M., Magill, S. S., Pollock, D. A., See, I., Soe, M. M., Walters, M. S., et al. (2019) · Infection Control and Hospital Epidemiology · doi:10.1017/ice.2019.296 · Cited by 716 · see citing works
Extraintestinal Pathogenic Escherichia coli: A Combination of Virulence with Antibiotic Resistance
Pitout, J. D. D. (2012) · Frontiers in Microbiology · doi:10.3389/fmicb.2012.00009 · Cited by 471 · see citing works
Pandemic lineages of extraintestinal pathogenic Escherichia coli
Riley, L. W. (2014) · Clinical Microbiology and Infection · doi:10.1111/1469-0691.12646 · Cited by 412 · see citing works
Rhee, C., Kadri, S. S., Dekker, J. P., Danner, R. L., Chen, H.-C., Fram, D., Zhang, F., Wang, R., Klompas, M., & Program, F. T. C. P. E. (2020) · JAMA Network Open · doi:10.1001/jamanetworkopen.2020.2899 · Cited by 397 · see citing works
de Kraker, M. E. A., Jarlier, V., Monen, J., Heuer, O. E., van de Sande-Bruinsma, N., & Grundmann, H. (2012) · Clinical Microbiology and Infection · doi:10.1111/1469-0691.12028 · Cited by 384 · see citing works
Epidemiology of Escherichia coli Bacteremia: A Systematic Literature Review
Bonten, M. J. M., Johnson, J. R., van den Biggelaar, A. H. J., Georgalis, L., Geurtsen, J., de Palacios, P. I., Gravenstein, S., Verstraeten, T., Hermans, P. W. M., & POOLMAN, J. T. (2020) · Clinical Infectious Diseases · doi:10.1093/cid/ciaa210 · Cited by 338 · see citing works
Self-citationPopulation-Based Epidemiology and Microbiology of Community-Onset Bloodstream Infections
Laupland, K. B., & Church, D. L. (2014) · Clinical Microbiology Reviews · doi:10.1128/cmr.00002-14 · Cited by 321 · see citing works
Poolman, J. T., & Wacker, M. (2016) · Journal of Infectious Diseases · doi:10.1093/infdis/jiv429 · Cited by 246 · see citing works
Self-citationEscherichia coli ST131: a multidrug-resistant clone primed for global domination
Pitout, J. D. D., & DeVinney, R. (2017) · F1000Research · doi:10.12688/f1000research.10609.1 · Cited by 245 · see citing works
Laupland, K. B., Gregson, D. B., Church, D. L., Ross, T., & Pitout, J. D. D. (2008) · Clinical Microbiology and Infection · doi:10.1111/j.1469-0691.2008.02089.x · Cited by 222 · see citing works
A complete view of the genetic diversity of the Escherichia coli O-antigen biosynthesis gene cluster
Iguchi, A., Iyoda, S., Kikuchi, T., Ogura, Y., Katsura, K., Ohnishi, M., Hayashi, T., & Thomson, N. R. (2014) · DNA Research · doi:10.1093/dnares/dsu043 · Cited by 165 · see citing works
DebRoy, C., Fratamico, P. M., Yan, X., Baranzoni, G. M., Liu, Y., Needleman, D. S., Tebbs, R. S., O’Connell, C. D., Allred, A. F., Swimley, M. S., et al. (2016) · PLoS ONE · doi:10.1371/journal.pone.0147434 · Cited by 118 · see citing works
Self-citationFrenck, R. W., Ervin, J. E., Chu, L., Abbanat, D., Spiessens, B., Go, O. T., Haazen, W., van den Dobbelsteen, G., POOLMAN, J. T., Thoelen, S., et al. (2019) · The Lancet Infectious Diseases · doi:10.1016/s1473-3099(18)30803-x · Cited by 88 · see citing works
Self-citationAssessment of Health Care Exposures and Outcomes in Adult Patients With Sepsis and Septic Shock
Fay, K. T., Sapiano, M. R. P., Gokhale, R. H., Dantes, R., Thompson, N. D., Katz, D. E., Ray, S. M., Wilson, L. E., Perlmutter, R., Nadle, J., et al. (2020) · JAMA Network Open · doi:10.1001/jamanetworkopen.2020.6004 · Cited by 86 · see citing works
BSAC standardized disc susceptibility testing method (version 10)
Andrews, J. M., Howe, R. A., & Testing, F. T. B. W. P. O. S. (2011) · Journal of Antimicrobial Chemotherapy · doi:10.1093/jac/dkr359 · Cited by 84 · see citing works
Begier, E. M., Rosenthal, N. A., Gurtman, A., Kartashov, A. I., Donald, R. G. K., & Lockhart, S. P. (2021) · Clinical Infectious Diseases · doi:10.1093/cid/ciab005 · Cited by 46 · see citing works
Goldstein, E., MacFadden, D. R., Karaca, Z., Steiner, C., Viboud, C. G., & Lipsitch, M. (2019) · International Journal of Antimicrobial Agents · doi:10.1016/j.ijantimicag.2019.03.004 · Cited by 45 · see citing works
George, D., & Manges, A. R. (2010) · Epidemiology and Infection · doi:10.1017/s0950268810001639 · Cited by 41 · see citing works
Trends in ExPEC serogroups in the UK and their significance
Ciesielczuk, H., Jenkins, C., Chattaway, M. A., Doumith, M., Hope, R., Woodford, N., & Wareham, D. W. (2016) · European Journal of Clinical Microbiology & Infectious Diseases · doi:10.1007/s10096-016-2707-8 · Cited by 33 · see citing works
Lipworth, S., Vihta, K.-D., Chau, K., Kavanagh, J., Davies, T. J., George, S. A., Barker, L., Vaughan, A., Andersson, M. I., Jeffery, K. J., et al. (2021) · Clinical Infectious Diseases · doi:10.1093/cid/ciab006 · Cited by 33 · see citing works
Self-citationSynthesis and characterization of Escherichia coli O18 O-polysaccharide conjugate vaccines
Cryz, S. J., Cross, A. S., SADOFF, J. C., & Fürer, E. (1990) · Infection and Immunity · doi:10.1128/iai.58.2.373-377.1990 · Cited by 31 · see citing works
Saade, E. A., Gravenstein, S., Donskey, C. J., Wilson, B. M., Spiessens, B., Abbanat, D., POOLMAN, J. T., de Palacios, P. I., & Hermans, P. W. M. (2020) · Vaccine · doi:10.1016/j.vaccine.2020.06.024 · Cited by 17 · see citing works
Self-citationVerboom, D. M., Varkila, M. R. J., Morrow, B. E., Davies, T. A., de Palacios, P. I., POOLMAN, J. T., Hermans, P. W. M., Dudley, E. G., Roberts, E. L., Cremer, O. L., et al. (2021) · Vaccine · doi:10.1016/j.vaccine.2021.02.031 · Cited by 11 · see citing works
Self-citationRoyer, G., Clermont, O., Condamine, B., Mercier-Darty, M., Laouenan, C., Lefort, A., Denamur, É., LASTOURS, V. D., Groups, C. A. S., Wolff, M., et al. (2021) · Clinical Infectious Diseases · doi:10.1093/cid/ciab458 · Cited by 9 · see citing works
Flagged first, then by citations
Cited by
Sorted by citations
Vaccines against extraintestinal pathogenic Escherichia coli (ExPEC): progress and challenges
Qiu, L., Chirman, D. M., Clark, J. R., Xing, Y., Santos, H. H., Vaughan, E. E., & Maresso, A. W. (2024) · Gut Microbes · doi:10.1080/19490976.2024.2359691 · Cited by 38 · see citing works
Fierro, C. A., Sarnecki, M., Doua, J., Spiessens, B., Go, O. T., Davies, T. A., van den Dobbelsteen, G., POOLMAN, J. T., Abbanat, D., & Haazen, W. (2023) · Open Forum Infectious Diseases · doi:10.1093/ofid/ofad417 · Cited by 31 · see citing works
Self-citationVaccines and monoclonal antibodies to prevent healthcare-associated bacterial infections
Sauvat, L., Verhoeven, P., Gagnaire, J., Berthelot, P., Paul, S., Botelho-Nevers, E., & Gagneux-Brunon, A. (2024) · Clinical Microbiology Reviews · doi:10.1128/cmr.00160-22 · Cited by 22 · see citing works
A randomized phase 1/2a trial of ExPEC10V vaccine in adults with a history of UTI
Fierro, C. A., Sarnecki, M., Spiessens, B., Go, O. T., Day, T., Davies, T. A., van den Dobbelsteen, G., POOLMAN, J. T., Abbanat, D., & Haazen, W. (2024) · npj Vaccines · doi:10.1038/s41541-024-00885-1 · Cited by 21 · see citing works
Self-citationCabrera, A., Mason, E. L., Mullins, L. P., & Sadarangani, M. (2025) · npj Antimicrobials and Resistance · doi:10.1038/s44259-025-00100-8 · Cited by 20 · see citing works
Nuin, E. A., Vilken, T., Xavier, B. B., Doua, J., Morrow, B. J., Geurtsen, J., Go, O. T., Spiessens, B., Sarnecki, M., POOLMAN, J. T., et al. (2024) · Journal of Antimicrobial Chemotherapy · doi:10.1093/jac/dkae182 · Cited by 18 · see citing works
Self-citationGladstone, R. A., Pesonen, M., Pöntinen, A. K., Mäklin, T., MacAlasdair, N., Thorpe, H. A., Shao, Y., Mallawaarachchi, S., Arredondo-Alonso, S., Parcell, B. J., et al. (2024) · medRxiv · doi:10.1101/2024.11.22.24317484 · Cited by 15 · see citing works
Yun, C. S., Moon, B., Hwang, M.-H., Lee, S., Ku, B., & Lee, K. (2023) · Scientific Reports · doi:10.1038/s41598-023-32287-z · Cited by 9 · see citing works
Chorro, L., Ndreu, D., Patel, A., Kodali, S., Li, Z.-H., Keeney, D. R., Dutta, K., Sasmal, A., Illenberger, A., Torres, C. L., et al. (2024) · Microbiology Spectrum · doi:10.1128/spectrum.04213-23 · Cited by 8 · see citing works
A Bioconjugate Vaccine Against Extra-Intestinal Pathogenic Escherichia coli (ExPEC)
Hao, L., Huang, W., Guo, Y., Liu, X., Wu, J., Zhu, L., Pan, C., & Wang, H. (2025) · Vaccines · doi:10.3390/vaccines13040362 · Cited by 8 · see citing works
Gladstone, R. A., Pesonen, M., Pöntinen, A. K., Mäklin, T., MacAlasdair, N., Thorpe, H. A., Shao, Y., Mallawaarachchi, S., Arredondo-Alonso, S., Parcell, B. J., et al. (2026) · Nature Microbiology · doi:10.1038/s41564-026-02283-w · Cited by 7 · see citing works
Anušić, M., Marijan, T., Mlinarić-Džepina, A., Tičić, V., Gršković, L., & Vraneš, J. (2025) · Antibiotics · doi:10.3390/antibiotics14020109 · Cited by 6 · see citing works
DMB labelling for detection and analysis of capsular polysaccharidesPreprint
Rutschmann, C., Vershynina, K., Mathew, C., Piëch, L., Sulewska, M., Schilling, P. E., Wenner, N., Larsson, L., Bertola, A., Barazzone, E. C., et al. (2025) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2025.01.29.635457 · Cited by 6 · see citing works
Di Pierro, F., Sagheddu, V., Galletti, S., Casaroli, A., Labrini, E., Soldi, S., Cazzaniga, M., Bertuccioli, A., Matera, M., Cavecchia, I., et al. (2026) · Probiotics and Antimicrobial Proteins · doi:10.1007/s12602-025-10522-5 · Cited by 5 · see citing works
“…to make serum-resistant the extra-intestinal pathogenic E. coli strains), and H1-type for flagella (responsible for strain motility) [26, 29, 30]; (iv) having two plasmids (pMUT1 and pMUT2) synthetizing microcins M and H47 (active against Salmonella strains) [26, 31, 32]; (v) being strong…”
Zhu, D., Li, X., Ma, T.-F., Chen, J., Ge, C.-H., Yang, S.-H., Zhang, W., Chen, J., Zhang, J., Qi, M.-M., et al. (2025) · Microbiology Research · doi:10.3390/microbiolres16030059 · Cited by 5 · see citing works
Han, R., Tang, C., Feng, Y., Li, T., Shen, S., Ding, L., Yang, W., Shi, Q., Yang, Y., Wu, S., et al. (2025) · International Journal of Antimicrobial Agents · doi:10.1016/j.ijantimicag.2025.107607 · Cited by 5 · see citing works
Extraintestinal Invasive Escherichia coli Infections in the US
Grome, H. N., Brandenburg, J. M., Kent, A. G., Curtis, L., Raymond, R. E., Ansari, U. A., Gargis, A. S., McKay, S. L., Parker, E., Driscoll, J., et al. (2026) · JAMA Network Open · doi:10.1001/jamanetworkopen.2025.57201 · Cited by 5 · see citing works
Shin, E.-J., Lee, S. J., Jeong, H.-J., & Lee, J.-H. (2023) · Food Control · doi:10.1016/j.foodcont.2023.110171 · Cited by 5 · see citing works
Pearse, O., Zuza, A. M., Tewesa, E., Siyabu, P., Fraser, A. J., Cornick, J., Kawaza, K., Musicha, P., Thomson, N. R., Feasey, N., et al. (2025) · Communications Medicine · doi:10.1038/s43856-025-01007-1 · Cited by 4 · see citing works
Geurtsen, J., Doua, J., Martı́nez-Martı́nez, L., de Palacios, P. I., Powis, J. E., Sims, M. D., Hermans, P. W. M., Barraud, O., Lanotte, P., Thaden, J. T., et al. (2025) · Epidemiology and Infection · doi:10.1017/s0950268825100344 · Cited by 4 · see citing works
Self-citationEconomic and Disease Burden Associated with Invasive Escherichia coli Disease in the United States
Schmidt, M. A., Blum, M., Donald, J. L., Meenan, R. T., Carrió, E., POOLMAN, J. T., Neary, M. P., Verstraeten, T., & Geurtsen, J. (2025) · Infectious Diseases and Therapy · doi:10.1007/s40121-025-01112-7 · Cited by 3 · see citing works
Self-citationAbdelkhalig, S. M., Elmanakhly, A. R., Alblwi, N. A. N., Alharbi, N. K., Alhomrani, M., Alamri, A. S., Alshehri, F., Mosbah, R., Safwat, N. A., Abdelrahman, M., et al. (2025) · Journal of Applied Microbiology · doi:10.1093/jambio/lxaf082 · Cited by 3 · see citing works
Slater, D., Vater, K. R. H., Sridhar, S., Hwang, W., Bielawski, D., Turbett, S. E., LaRocque, R. C., & Harris, J. B. (2024) · Microbiology Spectrum · doi:10.1128/spectrum.00375-24 · Cited by 2 · see citing works
Fazza, O., Karraouane, B., Kopprio, G. A., Bouchrif, B., En-nassiri, H., Ennachachibi, M. F., & Hmyene, A. (2025) · Microbial Pathogenesis · doi:10.1016/j.micpath.2025.107855 · Cited by 2 · see citing works
Madut, D. B., Rubach, M. P., Scheutz, F., Call, D. R., Gogry, F. A., Carugati, M., Kalengo, N. H., Marandu, A., Maze, M. J., Morrissey, A. B., et al. (2025) · The Journal of Infectious Diseases · doi:10.1093/infdis/jiaf437 · Cited by 2 · see citing works
Haindongo, E., Hakanen, A., Vainio, O., Vuopio, J., & Hedimbi, M. (2025) · BMC Infectious Diseases · doi:10.1186/s12879-025-12186-6 · Cited by 2 · see citing works
Li, M., Liu, X., Lan, R., Xiong, Y., Che, Y., Yixin, M., Li, H., Yan, G., Gao, H., Bai, X., et al. (2026) · Genome Medicine · doi:10.1186/s13073-026-01635-9 · Cited by 2 · see citing works
Vorimore, F., Tran, M.-L., Cointe, A., de Larminat, J., Bidet, P., Bonacorsi, S., Nodari, C. S., Weill, F., Fach, P., & Delannoy, S. (2026) · Applied and Environmental Microbiology · doi:10.1128/aem.02449-25 · Cited by 2 · see citing works
Ouattara, A. K., Ouédraogo, B., Tiemtoré, R. Y. W., Dabiré, A. M., Sougué, S., & Simporè, J. (2023) · OALib · doi:10.4236/oalib.1110534 · Cited by 2 · see citing works
POOLMAN, J. T., Geurtsen, J., & Weerdenburg, E. (2023) · Elsevier eBooks · doi:10.1016/b978-0-323-99967-0.00050-8 · Cited by 2 · see citing works
Self-citationHati, S., Vahora, S., Patel, S. S., Panchal, J., Patel, A. C., CHAUHAN, H. C., Sharma, K. K., Sabara, P. H., & Shrimali, M. D. (2025) · International Dairy Journal · doi:10.1016/j.idairyj.2025.106316 · Cited by 1 · see citing works
Palubeckaitė, I., Moran, A. B., Cramer, D. A. T., Torrente-López, A., Smits, W. K., Weerdenburg, E. M., Kaabi, A. A., Beurret, M., Anish, C., Wuhrer, M., et al. (2025) · Carbohydrate Polymers · doi:10.1016/j.carbpol.2025.123928 · Cited by 1 · see citing works
Self-citationFlórez-Navas, C., Josa, D. F., Silva, E., Ballesteros, N., Castañeda, S., Muñoz, M., Robayo-Amórtegui, H., Buitrago-Bernal, R., & Casallas-Barrera, J. O. (2025) · Journal of International Medical Research · doi:10.1177/03000605251404825 · Cited by 1 · see citing works
Cuchman, S., Benítez-Galeano, M. J., Gianneechini, E., Rivero, R., Rodríguez‐Osorio, N., Corvo, I., & Fontana, C. (2026) · Carbohydrate Polymers · doi:10.1016/j.carbpol.2026.125657 · Cited by 1 · see citing works
de Been, M., Ritmahan, W., Zomer, A., Go, O. T., Aitabi, M., Oriol-Mathieu, V., Willame, C., Geurtsen, J., & Weerdenburg, E. (2026) · Clinical Infectious Diseases · doi:10.1093/cid/ciag453 · Cited by 1 · see citing works
Self-citationNeary, M. P., Catillon, M., Ahmad, N., Gauthier‐Loiselle, M., Geurtsen, J., Qu, A., Willame, C., Cloutier, M., Khoury, A. C. E., & Saade, E. A. (2025) · Infectious Diseases and Therapy · doi:10.1007/s40121-024-01096-w · Cited by 1 · see citing works
Self-citationLepper, H. C., Pujol-Hodge, E., Hackman, J., van Zandvoort, K., Mellor-Wright, K., Lorenz, O., Lo, S. W., Dang, D. A., Do, T. H., Tonkin‐Hill, G. Q., et al. (2025) · medRxiv · doi:10.1101/2025.05.16.25327750 · Cited by 1 · see citing works
Hoshino, T., Takeuchi, N., Okada, H., Takahashi, K., Hirose, S., Nagasawa, K., Kitazawa, K., Igarashi, T., Asano, T., Obinata, K., et al. (2025) · Journal of Infection and Chemotherapy · doi:10.1016/j.jiac.2025.102825
Periasamy, S., Lübbers, J., King, S. B. S., Hovingh, E. S., van der Fits, L., & van den Dobbelsteen, G. P. J. M. (2026) · Frontiers in Immunology · doi:10.3389/fimmu.2026.1753331 · Cited by 2 · see citing works
Moran, A. B., Anish, C., Ravenscroft, N., Weerdenburg, E., Burghout, P., Grijpstra, J., Raghunath, M., Cramer, D. A. T., Torrente-López, A., Wuhrer, M., et al. (2026) · Carbohydrate Research · doi:10.1016/j.carres.2026.109888
Self-citationWeerdenburg, E., de Been, M., Zomer, A., Ritmahan, W., Lübbers, J., Moran, A. B., Nicolardi, S., Wuhrer, M., Ravenscroft, N., Anish, C., et al. (2026) · Scientific Reports · doi:10.1038/s41598-026-45688-7
Self-citationGersemann, A., Reiner, G., & von Berg, S. (2026) · Veterinary Sciences · doi:10.3390/vetsci13070666
Zhang, D., Ding, Y., Kang, W., Zhu, X., Cao, Z., Li, Y., Lai, J., Feng, J., Wang, X., Hou, G., et al. (2026) · Genome Medicine · doi:10.1186/s13073-026-01717-8
Opacic, M., Labovitiadi, O., de Goede, P., & Capelle, M. A. H. (2026) · Vaccines · doi:10.3390/vaccines14080690
Madut, D. B., Rubach, M. P., Costales, C., Rolfe, R. J., Carugati, M., Amsi, P. T., Mremi, A., Kalengo, N. H., Mosha, C., Marandu, A., et al. (2026) · American Journal of Clinical Pathology · doi:10.1093/ajcp/aqag088
Shastry, R., Shang, W., Janssen, S., Tete, S., Domínguez, E. G., van den Dobbelsteen, G., Davies, T. A., & Morrow, B. (2026) · Microbiology Spectrum · doi:10.1128/spectrum.00991-26
Self-citationZhang, D., Zou, P., Xiao, R., Li, J., Sheng, S., Xiao, R., Liang, X., & Wang, Y. (2026) · PLoS ONE · doi:10.1371/journal.pone.0354124
Hwang, Y., Cho, W. Y., Lee, W., Joo, I., Shin, J.-I., Seo, M.-R., Shin, S.-H., Ko, K. S., Park, K. T., Chung, Y.-J., et al. (2026) · The Journal of Microbiology · doi:10.71150/jm.2604011
Bonten, M. J. M., Butler, C. C., Edwards, A., Gravenstein, S., Ikeda, H., Johansen, I. S., Lambregts, M. M. C., Matsumoto, T., Patterson, D. L., Rodríguez‐Baño, J., et al. (2026) · The Lancet Infectious Diseases · doi:10.1016/s1473-3099(26)00469-x
Self-citation
- Authors
- Weerdenburg, E., Davies, T., Morrow, B., Zomer, A. L., Hermans, P., Go, O., Spiessens, B., van den Hoven, T., van Geet, G., Aitabi, M., DebRoy, C., Dudley, E. G., Bonten, M., Poolman, J., & Geurtsen, J.
- Affiliations
- Janssen (Netherlands) (NL)
- Janssen Research & Development (United States) (US)
- Utrecht University (NL)
- Janssen (Belgium) (BE)
- Janssen Integrated Data Analytics & Reporting , Beerse , Belgium
- Pennsylvania State University (US)
- University Medical Center Utrecht (NL)
- Corresponding author
- Hermans, Peter
- Geurtsen, Jeroen
- Venue
- Clinical Infectious Diseases
- Publisher
- Oxford University Press (OUP)
- Published
- 2022-06-10
- Volume
- 76
- Issue
- 3
- Pages
- e1236-e1243
- ISSN
- 1058-4838 (ISSN-L)
- 1537-6591
- PMC
- PMC9907479
- OpenAlex
- W4281740135
- Cited by
- 49
- References
- 31
- Citations by year
- 2026: 17 · 2025: 20 · 2024: 7 · 2023: 5
- FWCI
- 5.05
- Type
- journal article
- Language
- en
- Open access
- hybrid
- doi.org
- Licence
- Locations
- Clinical Infectious Diseases (publishedVersion, cc-by-nc-nd)
- PubMed Central (publishedVersion, cc-by-nc-nd)
- PubMed (publishedVersion)
- Utrecht University Repository (Utrecht University) (submittedVersion, other-oa)
- Funders
- Janssen Pharmaceuticals
- Topics
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Endocrinology › Escherichia coli research studies
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Medicine › Antibiotic Resistance in Bacteria
- Health Sciences › Medicine › Epidemiology › Urinary Tract Infections Management
- Keywords
- extraintestinal pathogenic Escherichia coli, O serotypes, bacteremia, multidrug resistance, antibiotic resistance, serotype distribution, older adults, bloodstream infection, antimicrobial susceptibility, global surveillance
- MeSH terms
- Extraintestinal Pathogenic Escherichia coli, Aged, Drug Resistance, Microbial, Escherichia coli, Escherichia coli Infections, Humans, Retrospective Studies, Bacteremia, Serogroup
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