The DOI matches its Crossref record; 3 of the 3 references it cites were found in a registry or an index.
Risk Factors for Severe Illness with 2009 Pandemic Influenza A (H1N1) Virus Infection in China
Open accessAbstract
BACKGROUND: Data on risk factors for severe outcomes from 2009 pandemic influenza A (H1N1) virus infection are limited outside of developed countries. METHODS: We reviewed medical charts to collect data from patients hospitalized with laboratory-confirmed 2009 H1N1 infection who were identified across China during the period from September 2009 through February 2010, and we analyzed potential risk factors associated with severe illness (defined as illness requiring intensive care unit admission or resulting in death). RESULTS: Among 9966 case patients, the prevalence of chronic medical conditions (33% vs 14%), pregnancy (15% vs 7%), or obesity (19% vs 14%) was significantly higher in those patients with severe illness than it was in those with less severe disease. In multivariable analyses, among nonpregnant case patients aged ≥ 2 years, having a chronic medical condition significantly increased the risk of severe outcome among all age groups, and obesity was a risk factor among those <60 years of age. The risk of severe illness among pregnant case patients was significantly higher for those in the second and third trimesters. The risk of severe illness was increased when oseltamivir treatment was initiated ≥ 5 days after illness onset (odds ratio, 1.42; 95% confidence interval, 1.20-1.67). For persons <60 years of age, the prevalence of obesity among case patients with severe illness was significantly greater than it was among those without severe illness or among the general population. CONCLUSIONS: Risk factors for severe 2009 H1N1 illness in China were similar to those observed in developed countries, but there was a lower prevalence of chronic medical conditions and a lower prevalence of obesity. Obesity was a risk factor among case patients < 60 years of age. Early initiation of oseltamivir treatment was most beneficial, and there was an increased risk of severe disease when treatment was started ≥ 5 days after illness onset.
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Hospitalized patients with 2009 H1N1 influenza in the United States, April-June 2009
Jain, S., Kamimoto, L., Bramley, A. M., Schmitz, A. M., Benoit, S. R., Louie, J., Sugerman, D. E., Druckenmiller, J. K., Ritger, K. A., Chugh, R., et al. (2009) · New England Journal of Medicine · doi:10.1056/nejmoa0906695 · Cited by 1,700
Self-citationCritically Ill Patients With 2009 Influenza A(H1N1) Infection in Canada
Kumar, A. (2009) · JAMA · doi:10.1001/jama.2009.1496 · Cited by 1,425
Critically Ill patients with 2009 influenza A(H1N1) in Mexico
Domínguez-Cherit, G. (2009) · JAMA · doi:10.1001/jama.2009.1536 · Cited by 840
Cited by
Epidemiology of Human Infections with Avian Influenza A(H7N9) Virus in China
Li, Q., Zhou, L., Zhou, M., Chen, Z., Li, F., Wu, H., Xiang, N., Chen, E., Tang, F., Wang, D., et al. (2014) · New England Journal of Medicine · doi:10.1056/nejmoa1304617 · Cited by 688
Self-citationObesity and the risk and outcome of infection
Huttunen, R., & Syrjänen, J. (2013) · International Journal of Obesity · doi:10.1038/ijo.2012.62 · Cited by 594
Qiao, J., Wang, Y., Li, X., Jiang, F., Zhang, Y., Ma, J., Song, Y., Ma, J., Fu, W., Pang, R., et al. (2021) · The Lancet · doi:10.1016/s0140-6736(20)32708-2 · Cited by 569
Self-citationRice, T. W., Rubinson, L., Uyeki, T. M., Vaughn, F. L., John, B. B., Miller, R. R., Higgs, E., Randolph, A. G., Smoot, B. E., & Thompson, B. T. (2012) · Critical Care Medicine · doi:10.1097/ccm.0b013e3182416f23 · Cited by 391
Self-citationObesity and ageing: Two sides of the same coin
Tam, B. T., Morais, J. A., & Santosa, S. (2020) · Obesity Reviews · doi:10.1111/obr.12991 · Cited by 253
Metadata
- Authors
- Yu, H., Feng, Z., Uyeki, T. M., Liao, Q., Zhou, L., Feng, L., Ye, M., Xiang, N., Huai, Y., Yuan, Y., Jiang, H., Zheng, Y., Gargiullo, P., Peng, Z., Feng, Y., Zheng, J., Xu, C., Zhang, Y., Shu, Y., Gao, Z., Yang, W., & Wang, Y.
- Venue
- Clinical Infectious Diseases
- Publisher
- Oxford University Press (OUP)
- Published
- 2011-02-15
- Volume
- 52
- Issue
- 4
- Pages
- 457-465
- ISSN
- 1058-4838 (ISSN-L)
- 1537-6591
- OpenAlex
- W2124517342
- Cited by
- 175
- References
- 3
- FWCI
- 14.70
- Type
- journal article
- Language
- en
- Open access
- bronze
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- Yu, H., Feng, Z., Uyeki, T. M., Liao, Q., Zhou, L., Feng, L., Ye, M., Xiang, N., Huai, Y., Yuan, Y., Jiang, H., Zheng, Y., Gargiullo, P., Peng, Z., Feng, Y., Zheng, J., Xu, C., Zhang, Y., Shu, Y., . . . Wang, Y. (2011). Risk Factors for Severe Illness with 2009 Pandemic Influenza A (H1N1) Virus Infection in China. Clinical Infectious Diseases. https://doi.org/10.1093/cid/ciq144
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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