CoChat
Sign Up
Cited by 117Antifungal resistance and susceptibilityYeasts and Rust Fungi StudiesFungal Infections and Studies

The DOI matches its Crossref record; 19 of the 19 references it cites were found in a registry or an index.

Vaginitis due to Saccharomyces cerevisiae: epidemiology, clinical aspects and therapy

Sobel, J. D., Vazquez, J., Lynch, M., Meriwether, C., Zervos, M. J.·1993·Clinical Infectious Diseases
DOI 10.1093/clinids/16.1.93
Open this paper in CoChat — free account

Abstract

Vaginitis due to Saccharomyces species is extremely rare. Nine patients with 20 vaginal isolates of Saccharomyces cerevisiae who presented with either asymptomatic vaginal colonization or symptomatic vaginitis indistinguishable from that caused by Candida albicans are described. All patients had a history of chronic or recurrent vaginitis, and all but two had systemic or local predisposing factors. In vitro tests of antimycotic sensitivity revealed reduced susceptibility of S. cerevisiae to the majority of available azole agents, with outright resistance to fluconazole. In accordance with these findings, the clinical response to conventional topical and oral antimycotic drugs was frequently suboptimal and incomplete. Electrophoretic karyotyping of strains revealed several distinct types of S. cerevisiae; this information permitted both longitudinal follow-up and differentiation of relapse from reinfection. In three patients with recurrent vaginitis, a unique epidemiological relationship was documented between S. cerevisiae and Torulopsis glabrata, another unusual and resistant vaginal pathogen. Isolation of S. cerevisiae from the vagina of symptomatic patients should not be ignored; treatment of vaginal infection with this yeast requires selected, often prolonged therapy.

Overview

Integrity signals

Registry

Crossref · 10.1093/clinids/16.1.93

Cites

19 of 19 references verified0 citation errors · 0 not checkable

Statistics

Recomputing p-values needs the paper’s full text.

Verification

Claims the paper makes

This paper’s full text isn’t openly available, so its claims and self-check weren’t run. The registry and citation checks still apply.

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

Citations

Cites

Flagged first, then by citations

Cited by

Sorted by citations

See all 117

Related

See all

Metadata

Authors
Sobel, J. D., Vazquez, J., Lynch, M., Meriwether, C., & Zervos, M. J.
Affiliations
Wayne State University (US)
Corresponding author
Sobel, J. D.
ORCID
Venue
Clinical Infectious Diseases
Publisher
Oxford University Press (OUP)
Published
1993-01-01
Volume
16
Issue
1
Pages
93-99
ISSN
  • 1058-4838 (ISSN-L)
  • 1537-6591
DOI
10.1093/clinids/16.1.93
OpenAlex
W2109797093
Cited by
117
References
19
Citations by year
2026: 2 · 2025: 4 · 2024: 5 · 2022: 1 · 2021: 5 · 2020: 3 · 2019: 3 · 2018: 2 · 2017: 2 · 2016: 2 · 2015: 6 · 2014: 3 · 2013: 1 · 2012: 4
FWCI
4.96
Type
journal article
Language
en
Open access
closed
Locations
  • Clinical Infectious Diseases (publishedVersion)
  • PubMed (publishedVersion)
Topics
  • Health Sciences › Medicine › Infectious Diseases › Antifungal resistance and susceptibility
  • Life Sciences › Immunology and Microbiology › Microbiology › Yeasts and Rust Fungi Studies
  • Health Sciences › Medicine › Infectious Diseases › Fungal Infections and Studies
Keywords
Saccharomyces cerevisiae, vaginal candidiasis, vaginal infection, recurrent vaginitis, Candida albicans, azole resistance, fluconazole resistance, Candida glabrata, relapse versus reinfection, vaginal colonization, antifungal therapy
MeSH terms
Adult, Antifungal Agents, Female, Humans, Microbial Sensitivity Tests, Middle Aged, Mycoses, Recurrence, Saccharomyces cerevisiae, Vagina, Vaginitis

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review