The DOI matches its Crossref record; 31 of the 31 references it cites were found in a registry or an index.
The Human Intestinal Microbiome: A New Frontier of Human Biology
Open accessAbstract
To analyze the vast number and variety of microorganisms inhabiting the human intestine, emerging metagenomic technologies are extremely powerful. The intestinal microbes are taxonomically complex and constitute an ecologically dynamic community (microbiota) that has long been believed to possess a strong impact on human physiology. Furthermore, they are heavily involved in the maturation and proliferation of human intestinal cells, helping to maintain their homeostasis and can be causative of various diseases, such as inflammatory bowel disease and obesity. A simplified animal model system has provided the mechanistic basis for the molecular interactions that occur at the interface between such microbes and host intestinal epithelia. Through metagenomic analysis, it is now possible to comprehensively explore the genetic nature of the intestinal microbiome, the mutually interacting system comprising the host cells and the residing microbial community. The human microbiome project was recently launched as an international collaborative research effort to further promote this newly developing field and to pave the way to a new frontier of human biology, which will provide new strategies for the maintenance of human health.
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Cites
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Cited by
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Interaction of dietary compounds, especially polyphenols, with the intestinal microbiota: a review
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Nonalcoholic fatty liver disease and aging: epidemiology to management.
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Metadata
- Authors
- Hattori, M., & Taylor, T. D.
- Venue
- DNA Research
- Publisher
- Oxford University Press (OUP)
- Published
- 2009-01-08
- Volume
- 16
- Issue
- 1
- Pages
- 1-12
- ISSN
- 1340-2838 (ISSN-L)
- 1756-1663
- OpenAlex
- W2125755185
- Cited by
- 281
- References
- 31
- FWCI
- 11.04
- Type
- journal article
- Language
- en
- Open access
- gold
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.