Efficacy of digital health interventions on depression and anxiety in patients with cardiac disease: a systematic review and meta-analysis
Open accessAbstract
Abstract Aims Depression and anxiety have a detrimental effect on the health outcomes of patients with heart disease. Digital health interventions (DHIs) could offer a solution to treat depression and anxiety in patients with heart disease, but evidence of its efficacy remains scarce. This review summarizes the latest data about the impact of DHIs on depression/anxiety in patients with cardiac disease. Methods and results Articles from 2000 to 2021 in English were searched through electronic databases (PubMed, Cochrane Library, and Embase). Articles were included if they incorporated a randomized controlled trial design for patients with cardiac disease and used DHIs in which depression or anxiety was set as outcomes. A systematic review and meta-analysis were performed. A total of 1675 articles were included and the screening identified a total of 17 articles. Results indicated that telemonitoring systems have a beneficial effect on depression [standardized mean difference for depression questionnaire score −0.78 (P = 0.07), −0.55 (P < 0.001), for with and without involving a psychological intervention, respectively]. Results on PC or cell phone–based psychosocial education and training have also a beneficial influence on depression [standardized mean difference for depression questionnaire score −0.49 (P = 0.009)]. Conclusion Telemonitoring systems for heart failure and PC/cell phone–based psychosocial education and training for patients with heart failure or coronary heart disease had a beneficial effect especially on depression. Regarding telemonitoring for heart failure, this effect was reached even without incorporating a specific psychological intervention. These results illustrate the future potential of DHIs for mental health in cardiology.
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A recent meta-analysis found that web-based health interventions in cardiac patients have beneficial effects on depression.
“A recent meta-analysis found that web-based health interventions in cardiac patients have beneficial effects on depression.17”
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- Authors
- Kaihara, T., Scherrenberg, M., Intan-Goey, V., Falter, M., Kindermans, H., Frederix, I., & Dendale, P.
- Affiliations
- St. Marianna University School of Medicine (JP)
- University of Antwerp (BE)
- Antwerp University Hospital (BE)
- Jessa Hospital (BE)
- Hasselt University (BE)
- Corresponding author
- Kaihara, Toshiki
- ORCID
- Venue
- European Heart Journal - Digital Health
- Publisher
- Oxford University Press (OUP)
- Published
- 2022-07-21
- Volume
- 3
- Issue
- 3
- Pages
- 445-454
- ISSN
- 2634-3916 (ISSN-L)
- PMC
- PMC9707908
- OpenAlex
- W4286007497
- Cited by
- 29
- References
- 50
- Citations by year
- 2026: 12 · 2025: 8 · 2024: 5 · 2023: 4
- FWCI
- 0.75
- Type
- journal article
- Language
- en
- Open access
- gold
- doi.org
- Licence
- Locations
- European Heart Journal - Digital Health (publishedVersion, cc-by-nc)
- PubMed Central (publishedVersion, cc-by-nc)
- PubMed (publishedVersion)
- Document Server@UHasselt (UHasselt) (submittedVersion, cc-by-nc)
- Topics
- Social Sciences › Psychology › Applied Psychology › Digital Mental Health Interventions
- Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Cardiac Health and Mental Health
- Health Sciences › Health Professions › General Health Professions › Mobile Health and mHealth Applications
- Keywords
- digital health interventions, depression, anxiety, heart disease, heart failure, remote patient monitoring, psychosocial education, coronary artery disease, psychological intervention
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