The DOI matches its Crossref record; 2 of the 2 references it cites were found in a registry or an index.
The G·U wobble base pair: A fundamental building block of RNA structure crucial to RNA function in diverse biological systems
Open accessAbstract
The G·U wobble base pair is a fundamental unit of RNA secondary structure that is present in nearly every class of RNA from organisms of all three phylogenetic domains. It has comparable thermodynamic stability to Watson–Crick base pairs and is nearly isomorphic to them. Therefore, it often substitutes for G·C or A·U base pairs. The G·U wobble base pair also has unique chemical, structural, dynamic and ligand‐binding properties, which can only be partially mimicked by Watson–Crick base pairs or other mispairs. These features mark sites containing G·U pairs for recognition by proteins and other RNAs and allow the wobble pair to play essential functional roles in a remarkably wide range of biological processes.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
Mathews, D. H., Sabina, J., Zuker, M., & Turner, D. H. (1999) · Journal of Molecular Biology · doi:10.1006/jmbi.1999.2700 · Cited by 3,795
Codon—anticodon pairing: The wobble hypothesis
Crick, F. H. C. (1966) · Journal of Molecular Biology · doi:10.1016/s0022-2836(66)80022-0 · Cited by 2,029
Cited by
Kino, T., Hurt, D. E., Ichijo, T., Nader, N., & Chrousos, G. P. (2010) · Science Signaling · doi:10.1126/scisignal.2000568 · Cited by 1,231
Geometric nomenclature and classification of RNA base pairs
LEONTIS, N. B., & WESTHOF, E. (2001) · RNA · doi:10.1017/s1355838201002515 · Cited by 1,073
Giraud, T., Koch, M., Hoschtettler, P., Pickaert, G., Averlant‐Petit, M., & Stefan, L. (2026) · ACS Materials Au · doi:10.1021/acsmaterialsau.5c00240 · Cited by 716
tRNA’s Wobble Decoding of the Genome: 40 Years of Modification
Agris, P. F., Vendeix, F. A. P., & Graham, W. D. (2007) · Journal of Molecular Biology · doi:10.1016/j.jmb.2006.11.046 · Cited by 543
Visualizing transient Watson–Crick-like mispairs in DNA and RNA duplexes
Kimsey, I. J., Petzold, K., Sathyamoorthy, B., Stein, Z. W., & Al-Hashimi, H. M. (2015) · Nature · doi:10.1038/nature14227 · Cited by 261
Metadata
- Authors
- Varani, G., & McClain, W. H.
- Venue
- EMBO reports
- Published
- 2000-07
- Volume
- 1
- Issue
- 1
- Pages
- 18-23
- ISSN
- 1469-221X (ISSN-L)
- 1469-3178
- OpenAlex
- W1767395388
- Cited by
- 479
- References
- 2
- FWCI
- 1.80
- Type
- journal article
- Language
- en
- Open access
- green
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
How to cite
Cite CoChat for the checks on this page, and the paper for its own findings.
- This page
- CoChat. (2026). Citation check: The G·U wobble base pair: A fundamental building block of RNA structure crucial to RNA function in diverse biological systems. https://app.cochat.ai/papers/10.1093/embo-reports/kvd001
- The paper
- Varani, G., & McClain, W. H. (2000). The G·U wobble base pair: A fundamental building block of RNA structure crucial to RNA function in diverse biological systems. EMBO reports. https://doi.org/10.1093/embo-reports/kvd001
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
