Visualizing transient Watson–Crick-like mispairs in DNA and RNA duplexes

The M06 suite of density functionals for main group thermochemistry, thermochemical kinetics, noncovalent interactions, excited states, and transition elements: two new functionals and systematic testing of four M06-class functionals and 12 other functionals

Zhao, Y., & Truhlar, D. G. (2007) · Theoretical Chemistry Accounts · doi:10.1007/s00214-007-0310-x · Cited by 30,407 · see citing works

NMRPipe: A multidimensional spectral processing system based on UNIX pipes

Delaglio, F., Grzesiek, S., Vuister, G. W., Zhu, G., Pfeifer, J., & Bax, A. (1995) · Journal of Biomolecular NMR · doi:10.1007/bf00197809 · Cited by 15,994 · see citing works

Protein NMR Spectroscopy: Principles and Practice

Cavanagh, J. (1995) · Cited by 1,642 · see citing works

Reaction Rates by Nuclear Magnetic Resonance

McConnell, H. M. (1958) · The Journal of Chemical Physics · doi:10.1063/1.1744152 · Cited by 1,624 · see citing works

THE STRUCTURE OF DNAPreprint

Watson, J. D., & Crick, F. H. C. (1953) · Cold Spring Harbor Symposia on Quantitative Biology · doi:10.1101/sqb.1953.018.01.020 · Cited by 1,123 · see citing works

DNA Replication Fidelity

Kunkel, T. A., & Bebenek, K. (2000) · Annual Review of Biochemistry · doi:10.1146/annurev.biochem.69.1.497 · Cited by 1,003 · see citing works

Complementary base pairing and the origin of substitution mutations

Topal, M. D., & Fresco, J. R. (1976) · Nature · doi:10.1038/263285a0 · Cited by 843 · see citing works

DNA Replication Fidelity

Kunkel, T. A. (2004) · Journal of Biological Chemistry · doi:10.1074/jbc.r400006200 · Cited by 754 · see citing works

Selection of tRNA by the Ribosome Requires a Transition from an Open to a Closed Form

Ogle, J. M., Murphy, F. V., Tarry, M. J., & Ramakrishnan, V. (2002) · Cell · doi:10.1016/s0092-8674(02)01086-3 · Cited by 663 · see citing works

STRUCTURAL INSIGHTS INTO TRANSLATIONAL FIDELITY

Ogle, J. M., & Ramakrishnan, V. (2005) · Annual Review of Biochemistry · doi:10.1146/annurev.biochem.74.061903.155440 · Cited by 586 · see citing works

Structural Basis for Discriminative Regulation of Gene Expression by Adenine- and Guanine-Sensing mRNAs

Serganov, A., Yuan, Y.-R., Pikovskaya, O., Polonskaia, A., Malinina, L. V., Phan, A. T., Höbartner, C., Micura, R., Breaker, R. R., & Patel, D. J. (2004) · Chemistry & Biology · doi:10.1016/j.chembiol.2004.11.018 · Cited by 560 · see citing works

The G·U wobble base pair

Varani, G., & McClain, W. H. (2000) · EMBO Reports · doi:10.1093/embo-reports/kvd001 · Cited by 480 · see citing works

Errors and alternatives in reading the universal genetic code

Parker, J. (1989) · Microbiological Reviews · doi:10.1128/mr.53.3.273-298.1989 · Cited by 457 · see citing works

The use of NMR methods for conformational studies of nucleic acids

Wijmenga, S. S., & van Buuren, B. N. M. (1998) · Progress in Nuclear Magnetic Resonance Spectroscopy · doi:10.1016/s0079-6565(97)00023-x · Cited by 391 · see citing works

Kinetic determinants of high-fidelity tRNA discrimination on the ribosome.

Gromadski, K. B., & Rodnina, M. (2004) · Molecules and Cells · doi:10.1016/s1097-2765(04)00005-x · Cited by 377 · see citing works

A new understanding of the decoding principle on the ribosome

Demeshkina, N., Jenner, L. B., Westhof, É., Yusupov, M., & Yusupova, G. Z. (2012) · Nature · doi:10.1038/nature10913 · Cited by 372 · see citing works

Characterization of the Dynamics of Biomacromolecules Using Rotating-Frame Spin Relaxation NMR Spectroscopy

Palmer, A. G. I., & Massi, F. (2006) · Chemical Reviews · doi:10.1021/cr0404287 · Cited by 355 · see citing works

Transient Hoogsteen base pairs in canonical duplex DNA

Nikolova, E. N., Kim, E., Wise, A. A., O’Brien, P., Andricioaei, I., & Al‐Hashimi, H. M. (2011) · Nature · doi:10.1038/nature09775 · Cited by 346 · see citing works

DNA polymerase insertion fidelity. Gel assay for site-specific kinetics.

Boosalis, M. S., Petruska, J. A., & Goodman, M. F. (1987) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(18)47850-7 · Cited by 334 · see citing works

Base selection, proofreading, and mismatch repair during DNA replication in Escherichia coli.

Schaaper, R. M. (1993) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(20)80446-3 · Cited by 305 · see citing works

Structures of Mismatch Replication Errors Observed in a DNA Polymerase

Johnson, S. J., & Beese, L. S. (2004) · Cell · doi:10.1016/s0092-8674(04)00252-1 · Cited by 300 · see citing works

The base substitution fidelity of eucaryotic DNA polymerases. Mispairing frequencies, site preferences, insertion preferences, and base substitution by dislocation.

Kunkel, T. A., & Alexander, P. S. (1986) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(17)42446-x · Cited by 299 · see citing works

Structural Basis of the Translational Elongation Cycle

Voorhees, R. M., & Ramakrishnan, V. (2013) · Annual Review of Biochemistry · doi:10.1146/annurev-biochem-113009-092313 · Cited by 289 · see citing works

A 1H‐NMR thermometer suitable for cryoprobes

Findeisen, M., Brand, T., & Berger, S. T. A. (2006) · Magnetic Resonance in Chemistry · doi:10.1002/mrc.1941 · Cited by 273 · see citing works

Structural evidence for the rare tautomer hypothesis of spontaneous mutagenesis

Wang, W.-N., Hellinga, H. W., & Beese, L. S. (2011) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1114496108 · Cited by 265 · see citing works

Chemical exchange in biomacromolecules: Past, present, and future

Palmer, A. G. I. (2014) · Journal of Magnetic Resonance · doi:10.1016/j.jmr.2014.01.008 · Cited by 263 · see citing works

Nearest Neighbor Influences on DNA Polymerase Insertion Fidelity

Mendelman, L. V., Boosalis, M. S., Petruska, J. A., & Goodman, M. F. (1989) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(18)71695-5 · Cited by 239 · see citing works

Quality control by the ribosome following peptide bond formation

Zaher, H. S., & Green, R. (2008) · Nature · doi:10.1038/nature07582 · Cited by 224 · see citing works

Visualizing transient low-populated structures of RNA

Dethoff, E. A., Petzold, K., Chugh, J., Casiano‐Negroni, A., & Al‐Hashimi, H. M. (2012) · Nature · doi:10.1038/nature11498 · Cited by 212 · see citing works

Base pairing and fidelity in codon–anticodon interaction

Topal, M. D., & Fresco, J. R. (1976) · Nature · doi:10.1038/263289a0 · Cited by 202 · see citing works

Mechanism for expanding the decoding capacity of transfer RNAs by modification of uridines

Weixlbaumer, A., Murphy, F. V., Dziergowska, A., Małkiewicz, A. J., Vendeix, F. A. P., Agris, P. F., & Ramakrishnan, V. (2007) · Nature Structural & Molecular Biology · doi:10.1038/nsmb1242 · Cited by 196 · see citing works

Base pair opening within B-DNA: free energy pathways for GC and AT pairs from umbrella sampling simulations

Giudice, E. (2003) · Nucleic Acids Research · doi:10.1093/nar/gkg239 · Cited by 169 · see citing works

Catalytic Strategies of Self-Cleaving Ribozymes

Cochrane, J. C., & Strobel, S. A. (2008) · Accounts of Chemical Research · doi:10.1021/ar800050c · Cited by 167 · see citing works

The structural basis for the mutagenicity of O 6 -methyl-guanine lesions

Warren, J. J., Forsberg, L. J., & Beese, L. S. (2006) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0609580103 · Cited by 164 · see citing works

Replication infidelity via a mismatch with Watson–Crick geometry

Bębenek, K., Pedersen, L. C., & Kunkel, T. A. (2011) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1012825108 · Cited by 164 · see citing works

NMR R1ρ Rotating-Frame Relaxation with Weak Radio Frequency Fields

Massi, F., Johnson, E., Wang, C., Rance, M., & Palmer, A. G. I. (2004) · Journal of the American Chemical Society · doi:10.1021/ja038721w · Cited by 160 · see citing works

NMR of enzymatically synthesized uniformly 13C15N-labeled DNA oligonucleotides.

Zimmer, D. P., & Crothers, D. M. (1995) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.92.8.3091 · Cited by 135 · see citing works

Adaptive Ligand Binding by the Purine Riboswitch in the Recognition of Guanine and Adenine Analogs

Gilbert, S. D., Reyes, F. E., Edwards, A. L., & Batey, R. (2009) · Structure · doi:10.1016/j.str.2009.04.009 · Cited by 132 · see citing works

Off-Resonance R1ρ NMR Studies of Exchange Dynamics in Proteins with Low Spin-Lock Fields: An Application to a Fyn SH3 Domain

Korzhnev, D. M., Orekhov, V., & Kay, L. E. (2004) · Journal of the American Chemical Society · doi:10.1021/ja0446855 · Cited by 128 · see citing works

Measurement of histidine pK a values and tautomer populations in invisible protein states

Hansen, A. L., & Kay, L. E. (2014) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1400577111 · Cited by 127 · see citing works

Extending the Range of Microsecond-to-Millisecond Chemical Exchange Detected in Labeled and Unlabeled Nucleic Acids by Selective Carbon R1ρ NMR Spectroscopy

Hansen, A. L., Nikolova, E. N., Casiano‐Negroni, A., & Al‐Hashimi, H. M. (2009) · Journal of the American Chemical Society · doi:10.1021/ja8091399 · Cited by 124 · see citing works

Human DNA Polymerase ι Incorporates dCTP Opposite Template G via a G.C+ Hoogsteen Base Pair

Nair, D. T., Johnson, R. E., Prakash, L., Prakash, S., & Aggarwal, A. K. (2005) · Structure · doi:10.1016/j.str.2005.08.010 · Cited by 123 · see citing works

Nucleobase catalysis in ribozyme mechanism

Bevilacqua, P. C., & Yajima, R. (2006) · Current Opinion in Chemical Biology · doi:10.1016/j.cbpa.2006.08.014 · Cited by 119 · see citing works

Effect of 3' flanking neighbors on kinetics of pairing of dCTP or dTTP opposite O6-methylguanine in a defined primed oligonucleotide when Escherichia coli DNA polymerase I is used.

Singer, B. A., Chavez, F., Goodman, M. F., Essigmann, J. M., & Dosanjh, M. K. (1989) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.86.21.8271 · Cited by 115 · see citing works

The Effect of Tautomeric Constant on the Specificity of Nucleotide Incorporation during DNA Replication: Support for the Rare Tautomer Hypothesis of Substitution Mutagenesis

Harris, V. H., Smith, C. L., Cummins, W. J., Hamilton, A. L., Adams, H., Dickman, M. J., HORNBY, D. P., & Williams, D. M. (2003) · Journal of Molecular Biology · doi:10.1016/s0022-2836(03)00051-2 · Cited by 110 · see citing works

Longitudinal-Relaxation-Enhanced NMR Experiments for the Study of Nucleic Acids in Solution

Farjon, J., Boisbouvier, J., Schanda, P., Pardi, A., Simorre, J., & Brutscher, B. (2009) · Journal of the American Chemical Society · doi:10.1021/ja901633y · Cited by 109 · see citing works

Characterizing the Protonation State of Cytosine in Transient G·C Hoogsteen Base Pairs in Duplex DNA

Nikolova, E. N., Goh, G. B., Brooks, C. L., & Al‐Hashimi, H. M. (2013) · Journal of the American Chemical Society · doi:10.1021/ja400994e · Cited by 107 · see citing works

Structural studies of the O6meG.cntdot.C interaction in the d(C-G-C-G-A-A-T-T-C-O6meG-C-G) duplex

Patel, D. J., Shapiro, L. S., Kozlowski, S. A., Gaffney, B. L., & Jones, R. A. (1986) · Biochemistry · doi:10.1021/bi00353a012 · Cited by 106 · see citing works

Effects of solvent, protonation, and N-alkylation on the nitrogen-15 chemical shifts of pyridine and related compounds

Duthaler, R. O., & Roberts, J. D. (1978) · Journal of the American Chemical Society · doi:10.1021/ja00484a008 · Cited by 99 · see citing works

Ionization of bromouracil and fluorouracil stimulates base mispairing frequencies with guanine

Yu, H., Eritja, R., Bloom, L. B., & Goodman, M. F. (1993) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(18)82342-0 · Cited by 97 · see citing works

Active Site Dynamics in the Lead-Dependent Ribozyme

Hoogstraten, C. G., Wank, J. R., & Pardi, A. (2000) · Biochemistry · doi:10.1021/bi0007627 · Cited by 96 · see citing works

Dynamics of spontaneous flipping of a mismatched base in DNA duplex

Yin, Y., Yang, L., Zheng, G., Gu, C., Yi, C., He, C., Gao, Y. Q., & Zhao, X. S. (2014) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1400667111 · Cited by 93 · see citing works

Probing Transient Hoogsteen Hydrogen Bonds in Canonical Duplex DNA Using NMR Relaxation Dispersion and Single-Atom Substitution

Nikolova, E. N., Gottardo, F. L., & Al‐Hashimi, H. M. (2012) · Journal of the American Chemical Society · doi:10.1021/ja2117816 · Cited by 90 · see citing works

G/U and Certain Wobble Position Mismatches as Possible Main Causes of Amino Acid Misincorporations

Zhang, Z., Shah, B., & Bondarenko, P. V. (2013) · Biochemistry · doi:10.1021/bi401002c · Cited by 87 · see citing works

Theoretical study of R1ρ rotating-frame and R2 free-precession relaxation in the presence of n-site chemical exchange

Trott, O., & Palmer, A. G. I. (2004) · Journal of Magnetic Resonance · doi:10.1016/j.jmr.2004.06.005 · Cited by 83 · see citing works

Expanded use of sense codons is regulated by modified cytidines in tRNA

Cantara, W. A., Murphy, F. V., DeMi̇rci̇, H., & Agris, P. F. (2013) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1222641110 · Cited by 79 · see citing works

Tautomerism of 1-Methyl Derivatives of Uracil, Thymine, and 5-Bromouracil. Is Tautomerism the Basis for the Mutagenicity of 5-Bromouridine?

Orozco, M., Hernández, B., & Luque, F. J. (1998) · The Journal of Physical Chemistry B · doi:10.1021/jp981005+ · Cited by 77 · see citing works

The nature of the transition mismatches with Watson–Crick architecture: the G*·T or G·T* DNA base mispair or both? A QM/QTAIM perspective for the biological problem

Brovarets’, O. O., & Hovorun, D. М. (2014) · Journal of Biomolecular Structure and Dynamics · doi:10.1080/07391102.2014.924879 · Cited by 74 · see citing works

Opening Mechanism of G·T/U Pairs in DNA and RNA Duplexes: A Combined Study of Imino Proton Exchange and Molecular Dynamics Simulation

Várnai, P., Canalia, M., & Leroy, J. (2004) · Journal of the American Chemical Society · doi:10.1021/ja0470721 · Cited by 74 · see citing works

R1ρ relaxation for two-site chemical exchange: General approximations and some exact solutions

Miloushev, V. Z., & Palmer, A. G. I. (2005) · Journal of Magnetic Resonance · doi:10.1016/j.jmr.2005.07.023 · Cited by 73 · see citing works

Ionized and wobble base-pairing for bromouracil-guanine in equilibrium under physiological conditions

Sowers, L. C., Goodman, M. F., Eritja, R., Kaplan, B., & Fazakerley, G. V. (1989) · Journal of Molecular Biology · doi:10.1016/0022-2836(89)90353-7 · Cited by 72 · see citing works

Nitrogen-15 nuclear magnetic resonance studies on the tautomerism of 8-hydroxy-2'-deoxyguanosine, 8-hydroxyguanosine, and other C8-substituted guanine nucleosides

Cho, B. P., Kadlubar, F. F., Culp, S. J., & Evans, F. E. (1990) · Chemical Research in Toxicology · doi:10.1021/tx00017a010 · Cited by 71 · see citing works

A suite of Mathematica notebooks for the analysis of protein main chain 15N NMR relaxation data

Spyracopoulos, L. (2006) · Journal of Biomolecular NMR · doi:10.1007/s10858-006-9083-0 · Cited by 71 · see citing works

Kinetics of extension of O6-methylguanine paired with cytosine or thymine in defined oligonucleotide sequences

Dosanjh, M. K., Galeros, G., Goodman, M. F., & Singer, B. C. (1991) · Biochemistry · doi:10.1021/bi00113a015 · Cited by 67 · see citing works

Effect of reaction pH on the fidelity and processivity of exonuclease-deficient Klenow polymerase

Eckert, K. A., & Kunkel, T. A. (1993) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(19)38672-7 · Cited by 62 · see citing works

The spontaneous replication error and the mismatch discrimination mechanisms of human DNA polymerase β

Koag, M., Nam, K., & Lee, S. (2014) · Nucleic Acids Research · doi:10.1093/nar/gku789 · Cited by 56 · see citing works

Transition-state destabilization reveals how human DNA polymerase β proceeds across the chemically unstable lesion N7-methylguanine

Koag, M., Kou, Y., Ouzon‐Shubeita, H., & Lee, S. (2014) · Nucleic Acids Research · doi:10.1093/nar/gku554 · Cited by 53 · see citing works

Hydrogen Bonding Effects on the 15N and 1H Shielding Tensors in Nucleic Acid Base Pairs

Czernek, J., Fiala, R., & Sklenář, V. (2000) · Journal of Magnetic Resonance · doi:10.1006/jmre.2000.2091 · Cited by 52 · see citing works

Site-directed mutagenesis for quantitation of base-base interactions at defined sites

Singer, B. C., & Dosanjh, M. K. (1990) · Mutation research. Fundamental and molecular mechanisms of mutagenesis · doi:10.1016/0027-5107(90)90150-3 · Cited by 51 · see citing works

RB69 DNA Polymerase Structure, Kinetics, and Fidelity

Xia, S., & Konigsberg, W. H. (2014) · Biochemistry · doi:10.1021/bi4014215 · Cited by 49 · see citing works

Tautomerism provides a molecular explanation for the mutagenic properties of the anti-HIV nucleoside 5-aza-5,6-dihydro-2′-deoxycytidine

Li, D., Fedeles, B. I., Singh, V., Peng, C. S., Silvestre, K. J., Simi, A. K., Simpson, J. H., Tokmakoff, A., & Essigmann, J. M. (2014) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1405635111 · Cited by 47 · see citing works

Development and application of aromatic [13C, 1H] SOFAST-HMQC NMR experiment for nucleic acids

Sathyamoorthy, B., Lee, J., Kimsey, I. J., Ganser, L. R., & Al‐Hashimi, H. M. (2014) · Journal of Biomolecular NMR · doi:10.1007/s10858-014-9856-9 · Cited by 45 · see citing works

Is there adequate ionization mechanism of the spontaneous transitions? Quantum-chemical investigation

Brovarets’, O. O., Zhurakivsky, R. O., & Hovorun, D. М. (2010) · Biopolymers and Cell · doi:10.7124/bc.00016f · Cited by 44 · see citing works

Evaluating the uncertainty in exchange parameters determined from off-resonance R1ρ relaxation dispersion for systems in fast exchange

Bothe, J. R., Stein, Z. W., & Al‐Hashimi, H. M. (2014) · Journal of Magnetic Resonance · doi:10.1016/j.jmr.2014.04.010 · Cited by 43 · see citing works

Investigation of Chemical Shift and Structure Relationships in Nucleic Acids Using NMR and Density Functional Theory Methods

Xu, X., & Au‐Yeung, S. C. F. (2000) · The Journal of Physical Chemistry B · doi:10.1021/jp0007538 · Cited by 40 · see citing works

Comparative efficiency of forming m4T.cntdot.G versus m4T.cntdot.A base pairs at a unique site by use of Escherichia coli DNA polymerase I (Klenow fragment) and Drosophila melanogaster polymerase .alpha.-primase complex

Dosanjh, M. K., Essigmann, J. M., Goodman, M. F., & Singer, B. A. (1990) · Biochemistry · doi:10.1021/bi00471a026 · Cited by 35 · see citing works

Nitrogen-15-labeled oligodeoxynucleotides. 5. Use of 15N NMR to probe H-bonding in an O6MeG.cntdot.T base pair

Goswami, B., Gaffney, B. L., & Jones, R. A. (1993) · Journal of the American Chemical Society · doi:10.1021/ja00062a082 · Cited by 35 · see citing works

Direct Observation of Multiple Tautomers of Oxythiamine and their Recognition by the Thiamine Pyrophosphate Riboswitch

Singh, V., Peng, C. S., Li, D., Mitra, K., Silvestre, K. J., Tokmakoff, A., & Essigmann, J. M. (2013) · ACS Chemical Biology · doi:10.1021/cb400581f · Cited by 34 · see citing works

Why base tautomerization does not cause errors in mRNA decoding on the ribosome

Satpati, P., & Åqvist, J. (2014) · Nucleic Acids Research · doi:10.1093/nar/gku1044 · Cited by 30 · see citing works

Mispairs with Watson‐Crick base‐pair geometry observed in ternary complexes of an RB69 DNA polymerase variant

Xia, S., & Konigsberg, W. H. (2014) · Protein Science · doi:10.1002/pro.2434 · Cited by 25 · see citing works

Effect of pH on the base-mispairing properties of 5-bromouracil during DNA synthesis

Driggers, P. H., & Beattie, K. L. (1988) · Biochemistry · doi:10.1021/bi00405a052 · Cited by 22 · see citing works

DFT Calculations on the Effect of Solvation on the Tautomeric Reactions for Wobble Gua-Thy and Canonical Gua-Cyt Base-Pairs

Nomura, K., Hoshino, R., Shimizu, E., Hoshiba, Y., Danilov, V. I., & Kurita, N. (2013) · Journal of Modern Physics · doi:10.4236/jmp.2013.43a059 · Cited by 13 · see citing works

Stem cell divisions, somatic mutations, cancer etiology, and cancer prevention

Tomasetti, C., Li, L., & Vogelstein, B. (2017) · Science · doi:10.1126/science.aaf9011 · Cited by 1,113 · see citing works

RNA Structural Dynamics As Captured by Molecular Simulations: A Comprehensive Overview

Šponer, J., Bussi, G., Krepl, M., Banáš, P., Bottaro, S., Cunha, R. A., Gil-Ley, A., Pinamonti, G., Poblete, S., Jurečka, P., et al. (2018) · Chemical Reviews · doi:10.1021/acs.chemrev.7b00427 · Cited by 584 · see citing works

The roles of structural dynamics in the cellular functions of RNAs

Ganser, L. R., Kelly, M. L., Herschlag, D., & Al‐Hashimi, H. M. (2019) · Nature Reviews Molecular Cell Biology · doi:10.1038/s41580-019-0136-0 · Cited by 561 · see citing works

DSSR: an integrated software tool for dissecting the spatial structure of RNA

Lu, X.-J., Bussemaker, H., & Olson, W. (2015) · Nucleic Acids Research · doi:10.1093/nar/gkv716 · Cited by 349 · see citing works

Fundamental studies of functional nucleic acids: aptamers, riboswitches, ribozymes and DNAzymes

Micura, R., & Höbartner, C. (2020) · Chemical Society Reviews · doi:10.1039/d0cs00617c · Cited by 264 · see citing works

NMR spectroscopy captures the essential role of dynamics in regulating biomolecular function

Alderson, T. R., & Kay, L. E. (2021) · Cell · doi:10.1016/j.cell.2020.12.034 · Cited by 227 · see citing works

Structural basis for Cas9 off-target activity

Pacesa, M., Lin, C.-H., Cléry, A., Saha, A., Arantes, P. R., Bargsten, K., Irby, M. J., Allain, F. H.-T., Palermo, G., Cameron, P., et al. (2022) · Cell · doi:10.1016/j.cell.2022.09.026 · Cited by 198 · see citing works

Celebrating wobble decoding: Half a century and still much is new

Agris, P. F., Eruysal, E., Narendran, A., Väre, V. Y. P., Vangaveti, S., & Ranganathan, S. V. (2017) · RNA Biology · doi:10.1080/15476286.2017.1356562 · Cited by 190 · see citing works

Capturing snapshots of APE1 processing DNA damage

Freudenthal, B., Beard, W. A., Cuneo, M. J., Dyrkheeva, N. S., & Wilson, S. H. (2015) · Nature Structural & Molecular Biology · doi:10.1038/nsmb.3105 · Cited by 176 · see citing works

Quantum Biology: An Update and Perspective

Kim, Y., Bertagna, F., D’Souza, E. M., Heyes, D. J., Johannissen, L. O., Nery, E. T., Pantelias, A., Jiménez, A. S.-P., Slocombe, L., Spencer, M. G., et al. (2021) · Quantum Reports · doi:10.3390/quantum3010006 · Cited by 178 · see citing works

Protein dynamics and function from solution state NMR spectroscopy

Kovermann, M., Rogne, P., & Wolf‐Watz, M. (2016) · Quarterly Reviews of Biophysics · doi:10.1017/s0033583516000019 · Cited by 172 · see citing works

Chemical and Conformational Diversity of Modified Nucleosides Affects tRNA Structure and Function

Väre, V. Y. P., Eruysal, E., Narendran, A., Sarachan, K. L., & Agris, P. F. (2017) · Biomolecules · doi:10.3390/biom7010029 · Cited by 162 · see citing works

The chemical diversity of RNA modifications

Ontiveros, R. J., Stoute, J., & Liu, K. F. (2019) · Biochemical Journal · doi:10.1042/bcj20180445 · Cited by 157 · see citing works

Dynamic basis for dG•dT misincorporation via tautomerization and ionization

Kimsey, I. J., Szymanski, E. S., Zahurancik, W. J., Shakya, A., Xue, Y., Chu, C.-C., Sathyamoorthy, B., Suo, Z., & Al-Hashimi, H. M. (2018) · Nature · doi:10.1038/nature25487 · Cited by 152 · see citing works

Massively parallel kinetic profiling of natural and engineered CRISPR nucleases

Jones, S. K., Hawkins, J. A., Johnson, N. V., Jung, C., Hu, K., Rybarski, J. R., Chen, J. S., Doudna, J. A., Press, W. H., & Finkelstein, I. J. (2020) · Nature Biotechnology · doi:10.1038/s41587-020-0646-5 · Cited by 126 · see citing works

Structural insights into the translational infidelity mechanism

Rozov, A., Demeshkina, N., Westhof, É., Yusupov, M., & Yusupova, G. Z. (2015) · Nature Communications · doi:10.1038/ncomms8251 · Cited by 130 · see citing works

An open quantum systems approach to proton tunnelling in DNA

Slocombe, L., Sacchi, M., & Al-Khalili, J. (2022) · Communications Physics · doi:10.1038/s42005-022-00881-8 · Cited by 122 · see citing works

2′- O -Methylation can increase the abundance and lifetime of alternative RNA conformational states

Assi, H. A., Rangadurai, A., Shi, H., Liu, B., Clay, M. C., Erharter, K., Kreutz, C., Holley, C. L., & Al‐Hashimi, H. M. (2020) · Nucleic Acids Research · doi:10.1093/nar/gkaa928 · Cited by 109 · see citing works

N7 Methylation Alters Hydrogen-Bonding Patterns of Guanine in Duplex DNA

Kou, Y., Koag, M., & Lee, S. (2015) · Journal of the American Chemical Society · doi:10.1021/jacs.5b10172 · Cited by 92 · see citing works

Characterizing micro-to-millisecond chemical exchange in nucleic acids using off-resonance R1ρ relaxation dispersion

Rangadurai, A., Szymanski, E. S., Kimsey, I. J., Shi, H., & Al‐Hashimi, H. M. (2019) · Progress in Nuclear Magnetic Resonance Spectroscopy · doi:10.1016/j.pnmrs.2019.05.002 · Cited by 92 · see citing works

New Structural Insights into Translational Miscoding

Rozov, A., Demeshkina, N., Westhof, É., Yusupov, M., & Yusupova, G. Z. (2016) · Trends in Biochemical Sciences · doi:10.1016/j.tibs.2016.06.001 · Cited by 87 · see citing works

A guide to large-scale RNA sample preparation

Baronti, L., Karlsson, H., Marušič, M., & Petzold, K. (2018) · Analytical and Bioanalytical Chemistry · doi:10.1007/s00216-018-0943-8 · Cited by 87 · see citing works

The ribosome prohibits the G•U wobble geometry at the first position of the codon–anticodon helix

Rozov, A., Westhof, É., Yusupov, M., & Yusupova, G. Z. (2016) · Nucleic Acids Research · doi:10.1093/nar/gkw431 · Cited by 82 · see citing works

RNA Dynamics by NMR Spectroscopy

Marušič, M., Schlagnitweit, J., & Petzold, K. (2019) · ChemBioChem · doi:10.1002/cbic.201900072 · Cited by 82 · see citing works

Chemical Exchange

Palmer, A. G. I., & Koss, H. (2018) · Methods in enzymology on CD-ROM/Methods in enzymology · doi:10.1016/bs.mie.2018.09.028 · Cited by 81 · see citing works

How DNA polymerases catalyse replication and repair with contrasting fidelity

Wu, W.-J., Yang, W., & Tsai, M.-D. (2017) · Nature Reviews Chemistry · doi:10.1038/s41570-017-0068 · Cited by 76 · see citing works

NMR Chemical Exchange Measurements Reveal That N 6 -Methyladenosine Slows RNA Annealing

Shi, H., Liu, B., Nußbaumer, F., Rangadurai, A., Kreutz, C., & Al‐Hashimi, H. M. (2019) · Journal of the American Chemical Society · doi:10.1021/jacs.9b10939 · Cited by 67 · see citing works

Excited States of Nucleic Acids Probed by Proton Relaxation Dispersion NMR Spectroscopy

Juen, M. A., Wunderlich, C. H., Nußbaumer, F., Tollinger, M., Kontaxis, G., Konrat, R., Hansen, D. F., & Kreutz, C. (2016) · Angewandte Chemie International Edition · doi:10.1002/anie.201605870 · Cited by 66 · see citing works

A methyl-TROSY approach for NMR studies of high-molecular-weight DNA with application to the nucleosome core particle

Abramov, G., Vėlyvis, A., Rennella, E., Wong, L. E., & Kay, L. E. (2020) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.2004317117 · Cited by 64 · see citing works

Drug design from the cryptic inhibitor envelope

Lee, C.-J., Liang, X., Wu, Q., Najeeb, J., Zhao, J., Gopalaswamy, R., Titécat, M., Sebbane, F., Lemaître, N., Toone, E. J., et al. (2016) · Nature Communications · doi:10.1038/ncomms10638 · Cited by 64 · see citing works

Tautomerization-dependent recognition and excision of oxidation damage in base-excision DNA repair

Zhu, C., Lu, L., Zhang, J., Yue, Z., Song, J., Zong, S., Liu, M., Stovicek, O., Gao, Y. Q., & Yi, C. (2016) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1604591113 · Cited by 64 · see citing works

How many tautomerization pathways connect Watson–Crick-like G*·T DNA base mispair and wobble mismatches?

Brovarets’, O. O., & Hovorun, D. М. (2015) · Journal of Biomolecular Structure and Dynamics · doi:10.1080/07391102.2015.1046936 · Cited by 62 · see citing works

Direct NMR Evidence that Transient Tautomeric and Anionic States in dG·dT Form Watson–Crick-like Base Pairs

Szymanski, E. S., Kimsey, I. J., & Al‐Hashimi, H. M. (2017) · Journal of the American Chemical Society · doi:10.1021/jacs.7b01156 · Cited by 60 · see citing works

New structural hypostases of the A·T and G·C Watson–Crick DNA base pairs caused by their mutagenic tautomerisation in a wobble manner: a QM/QTAIM prediction

Brovarets’, O. O., & Hovorun, D. М. (2015) · RSC Advances · doi:10.1039/c5ra19971a · Cited by 58 · see citing works

Integrated structural biology to unravel molecular mechanisms of protein-RNA recognition

Schlundt, A., Tants, J., & Sattler, M. (2017) · Methods · doi:10.1016/j.ymeth.2017.03.015 · Cited by 58 · see citing works

G-quadruplex dynamics

Harkness, R. W., V, & Mittermaier, A. (2017) · Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics · doi:10.1016/j.bbapap.2017.06.012 · Cited by 55 · see citing works

Modulation of Hoogsteen dynamics on DNA recognition

Xu, Y., McSally, J., Andricioaei, I., & Al‐Hashimi, H. M. (2018) · Nature Communications · doi:10.1038/s41467-018-03516-1 · Cited by 55 · see citing works

Errors in translational decoding: tRNA wobbling or misincorporation?

Ou, X., Cao, J., Cheng, A., Peppelenbosch, M. P., & Pan, Q. (2019) · PLoS Genetics · doi:10.1371/journal.pgen.1008017 · Cited by 51 · see citing works

The influence of base pair tautomerism on single point mutations in aqueous DNA

Gheorghiu, A., Coveney, P. V., & Arabi, A. A. (2020) · Interface Focus · doi:10.1098/rsfs.2019.0120 · Cited by 52 · see citing works

Proton tunneling in the A∙T Watson-Crick DNA base pair: myth or reality?

Brovarets’, O. O., & Hovorun, D. М. (2015) · Journal of Biomolecular Structure and Dynamics · doi:10.1080/07391102.2015.1092886 · Cited by 49 · see citing works

A novel conception for spontaneous transversions caused by homo-pyrimidine DNA mismatches: a QM/QTAIM highlight

Brovarets’, O. O., & Hovorun, D. М. (2015) · Physical Chemistry Chemical Physics · doi:10.1039/c5cp03211c · Cited by 48 · see citing works

A quantitative model predicts how m6A reshapes the kinetic landscape of nucleic acid hybridization and conformational transitions

Liu, B., Shi, H., Rangadurai, A., Nußbaumer, F., Chu, C.-C., Erharter, K., Case, D. A., Kreutz, C., & Al‐Hashimi, H. M. (2021) · Nature Communications · doi:10.1038/s41467-021-25253-8 · Cited by 46 · see citing works

Integrative Structural Biology of Protein-RNA Complexes

Dimitrova-Paternoga, L., Jagtap, P. K. A., Chen, P., & Hennig, J. (2019) · Structure · doi:10.1016/j.str.2019.11.017 · Cited by 44 · see citing works

A Secondary Structural Element in a Wide Range of Fucosylated Glycoepitopes

Aeschbacher, T., Zierke, M., Smieško, M., Collot, M., Mallet, J., Ernst, B., Allain, F. H. ‐., & Schubert, M. (2017) · Chemistry - A European Journal · doi:10.1002/chem.201701866 · Cited by 45 · see citing works

A novel form of RNA double helix based on G·U and C·A+ wobble base pairing

Garg, A., & Heinemann, U. (2017) · RNA · doi:10.1261/rna.064048.117 · Cited by 44 · see citing works

Atomic structures of excited state A–T Hoogsteen base pairs in duplex DNA by combining NMR relaxation dispersion, mutagenesis, and chemical shift calculations

Shi, H., Clay, M. C., Rangadurai, A., Sathyamoorthy, B., Case, D. A., & Al‐Hashimi, H. M. (2018) · Journal of Biomolecular NMR · doi:10.1007/s10858-018-0177-2 · Cited by 44 · see citing works

Tautomeric G•U pairs within the molecular ribosomal grip and fidelity of decoding in bacteria

Rozov, A., Wolff, P., Grosjean, H., Yusupov, M., Yusupova, G. Z., & Westhof, É. (2018) · Nucleic Acids Research · doi:10.1093/nar/gky547 · Cited by 44 · see citing works

RNA modifications stabilize the tertiary structure of tRNAfMet by locally increasing conformational dynamics

Biedenbänder, T., de Jesus, V., Schmidt, M., Helm, M., Corzilius, B., & Fürtig, B. (2022) · Nucleic Acids Research · doi:10.1093/nar/gkac040 · Cited by 44 · see citing works

Massively parallel analysis of single-molecule dynamics on next-generation sequencing chips

Rivera, J. A., Mao, G., Владимирович, С. А., Panfilov, M., Hou, Q., Lindell, M., Chanez, C., Ritort, F., Jínek, M., & Deindl, S. (2024) · Science · doi:10.1126/science.adn5371 · Cited by 38 · see citing works

Physics‐based all‐atom modeling of RNA energetics and structure

Smith, L. G., Zhao, J., Mathews, D. H., & Turner, D. H. (2017) · Wiley Interdisciplinary Reviews - RNA · doi:10.1002/wrna.1422 · Cited by 40 · see citing works

Probing RNA Conformational Equilibria within the Functional Cellular Context

Ganser, L. R., Chu, C.-C., Bogerd, H. P., Kelly, M. L., Cullen, B. R., & Al‐Hashimi, H. M. (2020) · Cell Reports · doi:10.1016/j.celrep.2020.02.004 · Cited by 40 · see citing works

Incorporating uracil and 5-halouracils into short peptide nucleic acids for enhanced recognition of A–U pairs in dsRNAs

Patil, K. M., Toh, D. K., Yuan, Z. H., Meng, Z., Shu, Z., Zhang, H., Ong, A. A. L., Krishna, M. S., Lu, L., Lu, Y., et al. (2018) · Nucleic Acids Research · doi:10.1093/nar/gky631 · Cited by 39 · see citing works

Extending the Sensitivity of CEST NMR Spectroscopy to Micro‐to‐Millisecond Dynamics in Nucleic Acids Using High‐Power Radio‐Frequency Fields

Rangadurai, A., Shi, H., & Al‐Hashimi, H. M. (2020) · Angewandte Chemie International Edition · doi:10.1002/anie.202000493 · Cited by 39 · see citing works

Sensing the DNA-mismatch tolerance of catalytically inactive Cas9 via barcoded DNA nanostructures in solid-state nanopores

Sandler, S. E., Weckman, N. E., Yorke, S. K., Das, A., Chen, K., Gutierrez, R., & Keyser, U. F. (2023) · Nature Biomedical Engineering · doi:10.1038/s41551-023-01078-2 · Cited by 38 · see citing works

Wobble↔Watson-Crick tautomeric transitions in the homo-purine DNA mismatches: a key to the intimate mechanisms of the spontaneous transversions

Brovarets’, O. O., & Hovorun, D. М. (2015) · Journal of Biomolecular Structure and Dynamics · doi:10.1080/07391102.2015.1077737 · Cited by 38 · see citing works

A new color image encryption algorithm based on DNA and spatial chaotic map

Liu, P., Zhang, T., & Li, X. (2018) · Multimedia Tools and Applications · doi:10.1007/s11042-018-6758-y · Cited by 38 · see citing works

An intricate balance of hydrogen bonding, ion atmosphere and dynamics facilitates a seamless uracil to cytosine substitution in the U-turn of the neomycin-sensing riboswitch

Krepl, M., Vögele, J., Kruse, H., Duchardt, E., Wöhnert, J., & Šponer, J. (2018) · Nucleic Acids Research · doi:10.1093/nar/gky490 · Cited by 37 · see citing works

Dynamic ensemble of HIV-1 RRE stem IIB reveals non-native conformations that disrupt the Rev-binding site

Chu, C.-C., Plangger, R., Kreutz, C., & Al‐Hashimi, H. M. (2019) · Nucleic Acids Research · doi:10.1093/nar/gkz498 · Cited by 35 · see citing works

Chemical shift prediction of RNA imino groups: application toward characterizing RNA excited states

Wang, Y., Han, G., Jiang, X., Yuwen, T., & Xue, Y. (2021) · Nature Communications · doi:10.1038/s41467-021-21840-x · Cited by 36 · see citing works

The multiple flavors of GoU pairs in RNA

Westhof, É., Yusupov, M., & Yusupova, G. Z. (2019) · Journal of Molecular Recognition · doi:10.1002/jmr.2782 · Cited by 35 · see citing works

Structural insights into viral genome replication by the severe fever with thrombocytopenia syndrome virus L protein

Williams, H. M., Thorkelsson, S. R., Vogel, D., Milewski, M., Busch, C., Cusack, S., Grünewald, K., Quemin, E. R. J., & Rosenthal, M. (2022) · Nucleic Acids Research · doi:10.1093/nar/gkac1249 · Cited by 34 · see citing works

Iterative crRNA design and a PAM-free strategy enabled an ultra-specific RPA-CRISPR/Cas12a detection platform

Mao, X., Xu, J., Jiang, J., Li, Q., Yao, P., Jiang, J., Gong, L., Dong, Y., Tu, B., Wang, R., et al. (2024) · Communications Biology · doi:10.1038/s42003-024-07173-7 · Cited by 33 · see citing works

Capturing Excited States in the Fast‐Intermediate Exchange Limit in Biological Systems Using 1 H NMR Spectroscopy

Steiner, E., Schlagnitweit, J., Lundström, P., & Petzold, K. (2016) · Angewandte Chemie International Edition · doi:10.1002/anie.201609102 · Cited by 33 · see citing works

Revealing A-T and G-C Hoogsteen base pairs in stressed protein-bound duplex DNA

Shi, H., Kimsey, I. J., Gu, S., Liu, H.-F., Pham, U., Schumacher, M. A., & Al‐Hashimi, H. M. (2021) · Nucleic Acids Research · doi:10.1093/nar/gkab936 · Cited by 32 · see citing works

Structural Biology of RNA and Protein‐RNA Complexes after AlphaFold3

Hennig, J. (2025) · ChemBioChem · doi:10.1002/cbic.202401047 · Cited by 32 · see citing works

Non-dissociative structural transitions of the Watson-Crick and reverse Watson-Crick А·Т DNA base pairs into the Hoogsteen and reverse Hoogsteen forms

Brovarets’, O. O., Tsiupa, K. S., & Hovorun, D. М. (2018) · Scientific Reports · doi:10.1038/s41598-018-28636-y · Cited by 31 · see citing works

More than Proton Detection—New Avenues for NMR Spectroscopy of RNA

Schnieders, R., Keyhani, S., Schwalbe, H., & Fürtig, B. (2019) · Chemistry - A European Journal · doi:10.1002/chem.201903355 · Cited by 31 · see citing works

Studying sparsely populated conformational states in RNA combining chemical synthesis and solution NMR spectroscopy

Strebitzer, E., Nußbaumer, F., Kremser, J., Tollinger, M., & Kreutz, C. (2018) · Methods · doi:10.1016/j.ymeth.2018.05.007 · Cited by 31 · see citing works

A QM/QTAIM research under the magnifying glass of the DPT tautomerisation of the wobble mispairs involving 2-aminopurine

Brovarets’, O. O., Voiteshenko, I., Pérez‐Sánchez, H., & Hovorun, D. М. (2017) · New Journal of Chemistry · doi:10.1039/c7nj00717e · Cited by 30 · see citing works

Pol μ dGTP mismatch insertion opposite T coupled with ligation reveals promutagenic DNA repair intermediate

Çağlayan, M., & Wilson, S. H. (2018) · Nature Communications · doi:10.1038/s41467-018-06700-5 · Cited by 30 · see citing works

Demonstration that Small Molecules can Bind and Stabilize Low-abundance Short-lived RNA Excited Conformational States

Ganser, L. R., Kelly, M. L., Patwardhan, N. N., Hargrove, A. E., & Al‐Hashimi, H. M. (2019) · Journal of Molecular Biology · doi:10.1016/j.jmb.2019.12.009 · Cited by 30 · see citing works

Investigating Stability and Tautomerization of Gossypol—A Spectroscopy Study

Wang, L., Liu, Y., Zhang, Y., Yasin, A., & Zhang, L. (2019) · Molecules · doi:10.3390/molecules24071286 · Cited by 29 · see citing works

Environmental Effects on Guanine-Thymine Mispair Tautomerization Explored with Quantum Mechanical/Molecular Mechanical Free Energy Simulations

Li, P., Rangadurai, A., Al‐Hashimi, H. M., & Hammes‐Schiffer, S. (2020) · Journal of the American Chemical Society · doi:10.1021/jacs.0c03774 · Cited by 29 · see citing works

A robust and versatile method for production and purification of large-scale RNA samples for structural biology

Karlsson, H., Baronti, L., & Petzold, K. (2020) · RNA · doi:10.1261/rna.075697.120 · Cited by 28 · see citing works

Structural dynamics of double-stranded DNA with epigenome modification

Furukawa, A., Walinda, E., Arita, K., & Sugase, K. (2020) · Nucleic Acids Research · doi:10.1093/nar/gkaa1210 · Cited by 28 · see citing works

Structural grounds for the 2-aminopurine mutagenicity: a novel insight into the old problem of the replication errors

Brovarets’, O. O., Pérez‐Sánchez, H., & Hovorun, D. М. (2016) · RSC Advances · doi:10.1039/c6ra17787e · Cited by 27 · see citing works

An RNA-centric historical narrative around the Protein Data Bank

Westhof, É., & Leontis, N. B. (2021) · Journal of Biological Chemistry · doi:10.1016/j.jbc.2021.100555 · Cited by 26 · see citing works

DNA ligase I fidelity mediates the mutagenic ligation of pol β oxidized and mismatch nucleotide insertion products in base excision repair

Kamble, P., Hall, K., Chandak, M. S., Tang, Q., & Çağlayan, M. (2021) · Journal of Biological Chemistry · doi:10.1016/j.jbc.2021.100427 · Cited by 26 · see citing works

GRINS: Genetic elements that recode assembly-line polyketide synthases and accelerate their diversification

Nivina, A., Paredes, S. H., Fraser, H. B., & Khosla, C. (2021) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.2100751118 · Cited by 26 · see citing works

Influence of electron-withdrawing groups in two-photon absorption of imidazopyridines derivatives

Pelosi, A. G., Cocca, L. H. Z., Abegão, L. M. G., Sciuti, L. F., Piguel, S., Boni, L. D., & Mendonça, C. R. (2021) · Dyes and Pigments · doi:10.1016/j.dyepig.2021.109972 · Cited by 26 · see citing works

Recent Advances in DNA Nanostructures Applied in Sensing Interfaces and Cellular Imaging

Zhang, P., Ouyang, Y., Zhuo, Y., Chai, Y., & Yuan, R. (2023) · Analytical Chemistry · doi:10.1021/acs.analchem.2c04540 · Cited by 27 · see citing works

A Strategically Located Arg/Lys Residue Promotes Correct Base Paring During Nucleic Acid Biosynthesis in Polymerases

Genna, V., Carloni, P., & Vivo, M. D. (2018) · Journal of the American Chemical Society · doi:10.1021/jacs.7b12446 · Cited by 26 · see citing works

Structures of LIG1 that engage with mutagenic mismatches inserted by polβ in base excision repair

Tang, Q., Gulkis, M., McKENNA, R. V., & Çağlayan, M. (2022) · Nature Communications · doi:10.1038/s41467-022-31585-w · Cited by 25 · see citing works

Quantum Tunnelling Effects in the Guanine-Thymine Wobble Misincorporation via Tautomerism

Slocombe, L., Winokan, M., Al-Khalili, J., & Sacchi, M. (2022) · The Journal of Physical Chemistry Letters · doi:10.1021/acs.jpclett.2c03171 · Cited by 24 · see citing works

DNA Polymerase λ Active Site Favors a Mutagenic Mispair between the Enol Form of Deoxyguanosine Triphosphate Substrate and the Keto Form of Thymidine Template: A Free Energy Perturbation Study

Maximoff, S. N., Kamerlin, S. C. L., & Florián, J. (2017) · The Journal of Physical Chemistry B · doi:10.1021/acs.jpcb.7b04874 · Cited by 24 · see citing works

Probing conformational transitions towards mutagenic Watson–Crick-like G·T mismatches using off-resonance sugar carbon R1ρ relaxation dispersion

Rangadurai, A., Szymanski, E. S., Kimsey, I., Shi, H., & Al-Hashimi, H. M. (2020) · Journal of Biomolecular NMR · doi:10.1007/s10858-020-00337-7 · Cited by 24 · see citing works

The influence of external electric fields on proton transfer tautomerism in the guanine–cytosine base pair

Gheorghiu, A., Coveney, P. V., & Arabi, A. A. (2021) · Physical Chemistry Chemical Physics · doi:10.1039/d0cp06218a · Cited by 24 · see citing works

Inosine and its methyl derivatives: Occurrence, biogenesis, and function in RNA

Dutta, N., Deb, I., Sarzyńska, J., & Lahiri, A. (2022) · Progress in Biophysics and Molecular Biology · doi:10.1016/j.pbiomolbio.2022.01.001 · Cited by 23 · see citing works

MTH1 Substrate Recognition—An Example of Specific Promiscuity

Nissink, J. W. M., Biśta, M., Breed, J., Carter, N., Embrey, K. J., Read, J., & Winter-Holt, J. J. (2016) · PLoS ONE · doi:10.1371/journal.pone.0151154 · Cited by 24 · see citing works

Stable isotope labeling methods for DNA

Nelissen, F. H. T., Tessari, M., Wijmenga, S. S., & Heus, H. A. (2016) · Progress in Nuclear Magnetic Resonance Spectroscopy · doi:10.1016/j.pnmrs.2016.06.001 · Cited by 24 · see citing works

Complexity in pH-Dependent Ribozyme Kinetics: Dark pKa Shifts and Wavy Rate–pH Profiles

Frankel, E. A., & Bevilacqua, P. C. (2017) · Biochemistry · doi:10.1021/acs.biochem.7b00784 · Cited by 24 · see citing works

Characterizing Watson–Crick versus Hoogsteen Base Pairing in a DNA–Protein Complex Using Nuclear Magnetic Resonance and Site-Specifically 13C- and 15N-Labeled DNA

Zhou, H., Sathyamoorthy, B., Stelling, A. L., Xu, Y., Xue, Y., Pigli, Y. Z., Case, D. A., Rice, P. A., & Al‐Hashimi, H. M. (2019) · Biochemistry · doi:10.1021/acs.biochem.9b00027 · Cited by 24 · see citing works

The Molecular Tête‐à‐Tête between G‐Quadruplexes and the i‐motif in the Human Genome

Sengupta, P., Bose, D., & Chatterjee, S. (2020) · ChemBioChem · doi:10.1002/cbic.202000703 · Cited by 24 · see citing works

Whether 2-aminopurine induces incorporation errors at the DNA replication? A quantum-mechanical answer on the actual biological issue

Brovarets’, O. O., & Pérez‐Sánchez, H. (2016) · Journal of Biomolecular Structure and Dynamics · doi:10.1080/07391102.2016.1253504 · Cited by 23 · see citing works

Multi‐Site Conformational Exchange in the Synthetic Neomycin‐Sensing Riboswitch Studied by 19F NMR

Overbeck, J. H., Vögele, J., Nußbaumer, F., Duchardt, E., Kreutz, C., Wöhnert, J., & Sprangers, R. (2023) · Angewandte Chemie International Edition · doi:10.1002/anie.202218064 · Cited by 23 · see citing works

Symmetry in Nucleic-Acid Double Helices

Heinemann, U., & Roske, Y. (2020) · Symmetry · doi:10.3390/sym12050737 · Cited by 22 · see citing works

An RNA excited conformational state at atomic resolution

Geng, A., Ganser, L. R., Roy, R., Shi, H., Pratihar, S., Case, D. A., & Al‐Hashimi, H. M. (2023) · Nature Communications · doi:10.1038/s41467-023-43673-6 · Cited by 22 · see citing works

Mechanisms for guanine–cytosine tautomeric equilibrium in solution via steered molecular dynamic simulations

Tolosa, S., Sansón, J. A., & Hidalgo, A. (2017) · Journal of Molecular Liquids · doi:10.1016/j.molliq.2017.12.091 · Cited by 22 · see citing works

5‐Oxyacetic Acid Modification Destabilizes Double Helical Stem Structures and Favors Anionic Watson–Crick like cmo 5 U‐G Base Pairs

Strebitzer, E., Rangadurai, A., Plangger, R., Kremser, J., Juen, M. A., Tollinger, M., Al‐Hashimi, H. M., & Kreutz, C. (2018) · Chemistry - A European Journal · doi:10.1002/chem.201805077 · Cited by 22 · see citing works

Novel pathway for mutagenic tautomerization of classical А∙Т DNA base pairs via sequential proton transfer through quasi-orthogonal transition states: A QM/QTAIM investigation

Brovarets’, O. O., Tsiupa, K. S., & Hovorun, D. М. (2018) · PLoS ONE · doi:10.1371/journal.pone.0199044 · Cited by 21 · see citing works

Direct NMR Evidence that Transient Tautomeric and Anionic States in dG·dT Form Watson–Crick-like Base Pairs

Szymanski, E. S., Kimsey, I. J., & Al‐Hashimi, H. M. (2017) · Journal of the American Chemical Society · doi:10.1021/jacs.7b01156 · Cited by 60 · see citing works

Visualizing Rare Watson-Crick-Like Tautomeric and Anionic Mismatches in DNA and RNA

Kimsey, I. J. (2016) · DukeSpace (Duke University)

NMR measurements of transient low-populated tautomeric and anionic Watson–Crick-like G·T/U in RNA:DNA hybrids: implications for the fidelity of transcription and CRISPR/Cas9 gene editing

Szekely, O., Rangadurai, A., Gu, S., Manghrani, A., Guseva, S., & Al‐Hashimi, H. M. (2024) · Nucleic Acids Research · doi:10.1093/nar/gkae027 · Cited by 13 · see citing works

Watson-Crick Like Mismatches in Replication Fidelity

Rangadurai, A., Szymanski, E. S., Shi, H., & Al‐Hashimi, H. M. (2019) · Biophysical Journal · doi:10.1016/j.bpj.2018.11.1953

Insight into the conformational ensembles formed by U-U and T-T mismatches in RNA and DNA duplexes from a structure-based survey, NMR, and molecular dynamics simulations.

Geng, A., Roy, R., Gu, S., Guseva, S., Pratihar, S., Lee, Y., Li, L.-S., Kimsey, I. J., Wilson, M. A., & Al-Hashimi, H. M. (2025) · Journal of Molecular Biology · doi:10.1016/j.jmb.2025.169197 · Cited by 5 · see citing works